SI1028950T1 - Novi 7-substituirani kinazolin-2,4-dioni, uporabni kot protibakterijska zdravila - Google Patents

Novi 7-substituirani kinazolin-2,4-dioni, uporabni kot protibakterijska zdravila

Info

Publication number
SI1028950T1
SI1028950T1 SI9830412T SI9830412T SI1028950T1 SI 1028950 T1 SI1028950 T1 SI 1028950T1 SI 9830412 T SI9830412 T SI 9830412T SI 9830412 T SI9830412 T SI 9830412T SI 1028950 T1 SI1028950 T1 SI 1028950T1
Authority
SI
Slovenia
Prior art keywords
antibacterial agents
substituted quinazolin
diones useful
diones
useful
Prior art date
Application number
SI9830412T
Other languages
English (en)
Inventor
John Michael Domagala
Edmund Lee Ellsworth
Liren Huang
Thomas Eric Renau
Rajeshwar Singh
Michael Andrew Stier
Original Assignee
Warner-Lambert Company Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company Llc filed Critical Warner-Lambert Company Llc
Publication of SI1028950T1 publication Critical patent/SI1028950T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Furan Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI9830412T 1997-10-28 1998-09-23 Novi 7-substituirani kinazolin-2,4-dioni, uporabni kot protibakterijska zdravila SI1028950T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US6355697P 1997-10-28 1997-10-28
US9858898P 1998-08-31 1998-08-31
PCT/US1998/019877 WO1999021840A1 (en) 1997-10-28 1998-09-23 Novel 7-substituted quinazolin-2,4-diones useful as antibacterial agents
EP98948473A EP1028950B1 (en) 1997-10-28 1998-09-23 7-substituted quinazolin-2,4-diones useful as antibacterial agents

Publications (1)

Publication Number Publication Date
SI1028950T1 true SI1028950T1 (sl) 2003-08-31

Family

ID=26743531

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9830412T SI1028950T1 (sl) 1997-10-28 1998-09-23 Novi 7-substituirani kinazolin-2,4-dioni, uporabni kot protibakterijska zdravila

Country Status (11)

Country Link
US (2) US6331538B1 (sl)
EP (1) EP1028950B1 (sl)
AT (1) ATE239000T1 (sl)
AU (1) AU9503998A (sl)
DE (1) DE69814135T2 (sl)
DK (1) DK1028950T3 (sl)
ES (1) ES2195397T3 (sl)
PT (1) PT1028950E (sl)
SI (1) SI1028950T1 (sl)
WO (1) WO1999021840A1 (sl)
ZA (1) ZA989783B (sl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002534446A (ja) * 1999-01-13 2002-10-15 ワーナー−ランバート・カンパニー 4′ヘテロアリールジアリールアミン
EA005585B1 (ru) 2000-01-24 2005-04-28 Уорнер-Ламберт Компани 3-аминохиназолин-2,4-дионовые антибактериальные агенты
US7105682B2 (en) * 2001-01-12 2006-09-12 Amgen Inc. Substituted amine derivatives and methods of use
MXPA03010799A (es) 2001-05-30 2005-07-25 Warner Lambert Co Agentes antibacterianos.
JP2005501021A (ja) * 2001-06-19 2005-01-13 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 抗細菌剤
BR0307060A (pt) 2002-01-23 2004-10-26 Warner Lambert Co ésteres hidroxamato do ácido n-(fenil 4-substituìdo)-antranìlico
DOP2003000556A (es) 2002-01-23 2003-10-31 Warner Lambert Co Esteres hidroxamato de acido n-(4-fenil-sustituido)-antranilico.
CA2538420A1 (en) * 2003-09-12 2005-03-24 Warner-Lambert Company Llc Quinolone antibacterial agents
WO2005030131A2 (en) * 2003-09-23 2005-04-07 Replidyne, Inc Bis-quinazoline compounds for the treatment of bacterial infections
BRPI0506909A (pt) 2004-01-16 2007-05-29 Hoffmann La Roche derivados de 1-benzil-5piperazin-1-il-3,4 diidro-1h-quinazolin-2-ona e os respectivos derivados de 1h-benzo (1,2,6) tiadiazina-2,2-dióxido e 1,4-diidro-benzo (d) (1,3)oxazin-2-ona como moduladores do receptor de 5-hidroxitriptamina (5-ht) para o tratamento de doenças do sistema nervoso central
WO2006019965A2 (en) * 2004-07-16 2006-02-23 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
CA2590294A1 (en) * 2004-12-13 2006-06-22 Sunesis Pharmaceuticals, Inc. Pyrido pyrimidinones, dihydro pyrimido pyrimidinones and pteridinones useful as raf kinase inhibitors
US7973022B2 (en) * 2006-02-17 2011-07-05 Idexx Laboratories, Inc. Fluoroquinolone carboxylic acid salt compositions
WO2008061866A1 (en) * 2006-11-20 2008-05-29 Bayer Cropscience Sa New benzamide derivatives
PE20120325A1 (es) * 2009-05-19 2012-04-12 Dow Agrosciences Llc Aminopirimidinas sustituidas con arilo como agentes fungicidas
CN102458402B (zh) 2009-06-12 2013-10-02 百时美施贵宝公司 用作激酶调节剂的烟酰胺化合物
WO2011031745A1 (en) 2009-09-09 2011-03-17 Achaogen, Inc. Antibacterial fluoroquinolone analogs
WO2013076590A1 (en) * 2011-11-23 2013-05-30 Oxygen Healthcare Research Pvt. Ltd Benzothiazine compounds as h3 receptor ligands
WO2017051251A1 (en) * 2015-09-25 2017-03-30 Ludwig Institute For Cancer Research Ltd 3-hydroxy-quinazoline-2,4-dione derivatives and their use as nuclease modulators
TW202208355A (zh) 2020-05-04 2022-03-01 美商安進公司 作為骨髓細胞觸發受體2促效劑之雜環化合物及使用方法
IL297845A (en) 2020-05-04 2023-01-01 Amgen Inc Heterocyclic compounds as a stimulating receptor expressed in myeloid cells 2 agonists and methods of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1068263B (sl) 1959-11-05
US5155110A (en) * 1987-10-27 1992-10-13 Warner-Lambert Company Fenamic acid hydroxamate derivatives having cyclooxygenase and 5-lipoxygenase inhibition
US5283248A (en) 1989-11-21 1994-02-01 Hoffmann-La Roche Inc. Amino substituted pyrimido[1,6-2]benzimidazoles
JP3002507B2 (ja) 1990-08-03 2000-01-24 大日本製薬株式会社 四環式化合物

Also Published As

Publication number Publication date
ES2195397T3 (es) 2003-12-01
US20020115674A1 (en) 2002-08-22
ATE239000T1 (de) 2003-05-15
US6825199B2 (en) 2004-11-30
DE69814135T2 (de) 2004-04-01
US6331538B1 (en) 2001-12-18
EP1028950B1 (en) 2003-05-02
DE69814135D1 (de) 2003-06-05
DK1028950T3 (da) 2003-09-01
ZA989783B (en) 1999-04-28
WO1999021840A1 (en) 1999-05-06
EP1028950A1 (en) 2000-08-23
PT1028950E (pt) 2003-09-30
AU9503998A (en) 1999-05-17

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