ATE239000T1 - 7-substituierte chinazolin-2,4-dionen verwendbar als antibakterielle mittel - Google Patents

7-substituierte chinazolin-2,4-dionen verwendbar als antibakterielle mittel

Info

Publication number
ATE239000T1
ATE239000T1 AT98948473T AT98948473T ATE239000T1 AT E239000 T1 ATE239000 T1 AT E239000T1 AT 98948473 T AT98948473 T AT 98948473T AT 98948473 T AT98948473 T AT 98948473T AT E239000 T1 ATE239000 T1 AT E239000T1
Authority
AT
Austria
Prior art keywords
diones
antibacterial agents
usable
substituted quinazoline
compounds
Prior art date
Application number
AT98948473T
Other languages
English (en)
Inventor
John Michael Domagala
Edmund Lee Ellsworth
Liren Huang
Thomas Eric Renau
Rajeshwar Singh
Michael Andrew Stier
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of ATE239000T1 publication Critical patent/ATE239000T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT98948473T 1997-10-28 1998-09-23 7-substituierte chinazolin-2,4-dionen verwendbar als antibakterielle mittel ATE239000T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6355697P 1997-10-28 1997-10-28
US9858898P 1998-08-31 1998-08-31
PCT/US1998/019877 WO1999021840A1 (en) 1997-10-28 1998-09-23 Novel 7-substituted quinazolin-2,4-diones useful as antibacterial agents

Publications (1)

Publication Number Publication Date
ATE239000T1 true ATE239000T1 (de) 2003-05-15

Family

ID=26743531

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98948473T ATE239000T1 (de) 1997-10-28 1998-09-23 7-substituierte chinazolin-2,4-dionen verwendbar als antibakterielle mittel

Country Status (11)

Country Link
US (2) US6331538B1 (de)
EP (1) EP1028950B1 (de)
AT (1) ATE239000T1 (de)
AU (1) AU9503998A (de)
DE (1) DE69814135T2 (de)
DK (1) DK1028950T3 (de)
ES (1) ES2195397T3 (de)
PT (1) PT1028950E (de)
SI (1) SI1028950T1 (de)
WO (1) WO1999021840A1 (de)
ZA (1) ZA989783B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002534446A (ja) * 1999-01-13 2002-10-15 ワーナー−ランバート・カンパニー 4′ヘテロアリールジアリールアミン
SK10572002A3 (sk) 2000-01-24 2003-10-07 Warner-Lambert Company 3-Aminochinazolín-2,4-diónové antibakteriálne činidlá
US7105682B2 (en) * 2001-01-12 2006-09-12 Amgen Inc. Substituted amine derivatives and methods of use
EP1395585B1 (de) 2001-05-30 2006-01-04 Warner-Lambert Company LLC Antibakterielle mittel
CA2446963A1 (en) * 2001-06-19 2002-12-27 Warner-Lambert Company Llc Quinazolinediones as antibacterial agents
DOP2003000556A (es) 2002-01-23 2003-10-31 Warner Lambert Co Esteres hidroxamato de acido n-(4-fenil-sustituido)-antranilico.
WO2003062191A1 (en) 2002-01-23 2003-07-31 Warner-Lambert Company Llc N-(4-substituted phenyl)-anthranilic acid hydroxamate esters
WO2005026154A1 (en) * 2003-09-12 2005-03-24 Warner-Lambert Company Llc Quinolone antibacterial agents
US20050124562A1 (en) * 2003-09-23 2005-06-09 Joseph Guiles Bis-quinazoline compounds for the treatment of bacterial infections
AU2005205016B2 (en) 2004-01-16 2010-07-15 F. Hoffmann-La Roche Ag 1-benzyl-5-piperazin-1-yl-3,4 dihydro-1H-quinazolin-2-one derivatives and the respective 1H-benzo(1,2,6)thiadiazine-2,2-dioxide and 1,4-dihydro-benzo(D) (1,3)oxazin-2-one derivatives as modulators of the 5-hydroxytryptamine receptor (5-HT) for the treatment of diseases of the central nervous system
WO2006019965A2 (en) * 2004-07-16 2006-02-23 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
CA2590294A1 (en) 2004-12-13 2006-06-22 Sunesis Pharmaceuticals, Inc. Pyrido pyrimidinones, dihydro pyrimido pyrimidinones and pteridinones useful as raf kinase inhibitors
US7973022B2 (en) * 2006-02-17 2011-07-05 Idexx Laboratories, Inc. Fluoroquinolone carboxylic acid salt compositions
WO2008061866A1 (en) * 2006-11-20 2008-05-29 Bayer Cropscience Sa New benzamide derivatives
CA2760911A1 (en) * 2009-05-19 2010-11-25 George E. Davis Compounds and methods for controlling fungi
JP2012529535A (ja) 2009-06-12 2012-11-22 ブリストル−マイヤーズ スクイブ カンパニー キナーゼモジュレーターとして有用なニコチンアミド化合物
WO2011031745A1 (en) 2009-09-09 2011-03-17 Achaogen, Inc. Antibacterial fluoroquinolone analogs
WO2013076590A1 (en) * 2011-11-23 2013-05-30 Oxygen Healthcare Research Pvt. Ltd Benzothiazine compounds as h3 receptor ligands
US11253521B2 (en) 2015-09-25 2022-02-22 Ludwig Institute For Cancer Research Ltd 3-hydroxy-quinazoline-2,4-dione derivatives and their use as nuclease modulators
BR112022022338A2 (pt) 2020-05-04 2023-01-10 Amgen Inc Compostos heterocíclicos como receptor desencadeador expresso em agonistas de células mieloides 2 e métodos de uso
TW202208355A (zh) 2020-05-04 2022-03-01 美商安進公司 作為骨髓細胞觸發受體2促效劑之雜環化合物及使用方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1068263B (de) 1959-11-05
US5155110A (en) * 1987-10-27 1992-10-13 Warner-Lambert Company Fenamic acid hydroxamate derivatives having cyclooxygenase and 5-lipoxygenase inhibition
US5283248A (en) 1989-11-21 1994-02-01 Hoffmann-La Roche Inc. Amino substituted pyrimido[1,6-2]benzimidazoles
JP3002507B2 (ja) 1990-08-03 2000-01-24 大日本製薬株式会社 四環式化合物

Also Published As

Publication number Publication date
EP1028950A1 (de) 2000-08-23
ES2195397T3 (es) 2003-12-01
US6331538B1 (en) 2001-12-18
SI1028950T1 (en) 2003-08-31
US20020115674A1 (en) 2002-08-22
US6825199B2 (en) 2004-11-30
AU9503998A (en) 1999-05-17
DK1028950T3 (da) 2003-09-01
ZA989783B (en) 1999-04-28
DE69814135T2 (de) 2004-04-01
DE69814135D1 (de) 2003-06-05
PT1028950E (pt) 2003-09-30
EP1028950B1 (de) 2003-05-02
WO1999021840A1 (en) 1999-05-06

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