SI1017392T1 - Medicament formulation with a controlled release of an active agent - Google Patents

Medicament formulation with a controlled release of an active agent

Info

Publication number
SI1017392T1
SI1017392T1 SI9830242T SI9830242T SI1017392T1 SI 1017392 T1 SI1017392 T1 SI 1017392T1 SI 9830242 T SI9830242 T SI 9830242T SI 9830242 T SI9830242 T SI 9830242T SI 1017392 T1 SI1017392 T1 SI 1017392T1
Authority
SI
Slovenia
Prior art keywords
active agent
controlled release
medicament formulation
medicament
formulation
Prior art date
Application number
SI9830242T
Other languages
English (en)
Slovenian (sl)
Inventor
Hans-Martin Siefert
Patrick Bosche
Heino Stass
Stefan Kettelhoit
Tobias Laich
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of SI1017392T1 publication Critical patent/SI1017392T1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
SI9830242T 1997-09-25 1998-09-15 Medicament formulation with a controlled release of an active agent SI1017392T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19742243 1997-09-25
EP98946454A EP1017392B1 (de) 1997-09-25 1998-09-15 Arzneimittelformulierung mit kontrollierter wirkstofffreisetzung
PCT/EP1998/005842 WO1999015172A1 (de) 1997-09-25 1998-09-15 Arzneimittelformulierung mit kontrollierter wirkstofffreisetzung

Publications (1)

Publication Number Publication Date
SI1017392T1 true SI1017392T1 (en) 2002-12-31

Family

ID=7843534

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9830242T SI1017392T1 (en) 1997-09-25 1998-09-15 Medicament formulation with a controlled release of an active agent

Country Status (37)

Country Link
US (1) US6270799B1 (es)
EP (1) EP1017392B1 (es)
JP (2) JP2001517625A (es)
KR (1) KR100531065B1 (es)
CN (3) CN1895233A (es)
AR (3) AR013967A1 (es)
AT (1) ATE220547T1 (es)
AU (1) AU731693B2 (es)
BG (1) BG64745B1 (es)
BR (1) BR9812553B1 (es)
CA (1) CA2304135C (es)
CO (1) CO5011082A1 (es)
CZ (1) CZ293062B6 (es)
DE (1) DE59804823D1 (es)
DK (1) DK1017392T3 (es)
ES (1) ES2179533T3 (es)
GT (1) GT199800152A (es)
HK (1) HK1032010A1 (es)
HN (1) HN1998000144A (es)
HU (1) HU226583B1 (es)
ID (1) ID24259A (es)
IL (1) IL134591A0 (es)
MY (1) MY129437A (es)
NO (1) NO327492B1 (es)
NZ (1) NZ503538A (es)
PE (1) PE20000224A1 (es)
PL (1) PL192273B1 (es)
PT (1) PT1017392E (es)
SI (1) SI1017392T1 (es)
SK (1) SK283462B6 (es)
SV (1) SV1998000119A (es)
TR (1) TR200000752T2 (es)
TW (1) TW523412B (es)
UA (1) UA66812C2 (es)
UY (1) UY25192A1 (es)
WO (1) WO1999015172A1 (es)
ZA (1) ZA988718B (es)

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US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
AR020661A1 (es) * 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
DE10031043A1 (de) * 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
US20030091634A1 (en) * 2001-09-14 2003-05-15 Pawan Seth Delayed release tablet of venlafaxin
EP1482910A1 (en) * 2002-03-05 2004-12-08 Ranbaxy Laboratories, Ltd. Modified release oral pharmaceutical composition
ITMI20020515A1 (it) * 2002-03-12 2003-09-12 Jagotec Ag Sistema per il rilasco controllato di uno o piu' principi attivi
US7125563B2 (en) * 2002-04-12 2006-10-24 Dava Pharmaceuticals, Inc. Sustained release pharmaceutical preparations and methods for producing the same
US20050031683A1 (en) * 2003-08-04 2005-02-10 Ashish Kapoor Solid pharmaceutical composition
WO2005053655A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Method for making pharmaceutical multiparticulates
GB2409204A (en) * 2003-12-19 2005-06-22 Reckitt Benckiser Nv Plasticized thermoplastic polymer
DK1868581T3 (da) * 2005-04-11 2012-07-09 Abbott Lab Farmaceutiske sammensætninger med forbedrede opløsningsprofiler til dårligt opløselige lægemidler
WO2007033515A1 (fr) * 2005-09-21 2007-03-29 Shenzhen Tys R & D Co., Ltd. Formulation orale contenant de la moxifloxacine et son procédé de préparation
CN1762357B (zh) * 2005-09-21 2010-12-08 深圳市天一时科技开发有限公司 一种莫西沙星口服药物制剂及其制备方法
WO2007033522A1 (fr) * 2005-09-21 2007-03-29 Shenzhen Tys R & D Co., Ltd. Formulation de gélule contenant de la moxifloxacine et son procédé de préparation
PL2364141T5 (pl) 2008-12-08 2018-02-28 Ratiopharm Gmbh Kompaktorowana moksyfloksacyna
ITTO20110705A1 (it) * 2011-07-29 2013-01-30 Italiana Sint Spa Procedimento di preparazione della moxifloxacina cloridrato e relativi intermedi
KR20200077712A (ko) 2018-12-21 2020-07-01 한미약품 주식회사 목시플록사신 고형 제제 및 이의 제조방법

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US4002173A (en) 1974-07-23 1977-01-11 International Paper Company Diester crosslinked polyglucan hydrogels and reticulated sponges thereof
US3977404A (en) 1975-09-08 1976-08-31 Alza Corporation Osmotic device having microporous reservoir
US4207893A (en) 1977-08-29 1980-06-17 Alza Corporation Device using hydrophilic polymer for delivering drug to biological environment
FR2471186A1 (fr) * 1979-12-10 1981-06-19 Roussel Uclaf Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation
US4503030A (en) * 1983-06-06 1985-03-05 Alza Corporation Device for delivering drug to certain pH environments
CH668187A5 (de) 1986-08-07 1988-12-15 Ciba Geigy Ag Therapeutisches system mit systemischer wirkung.
ES2039287T3 (es) 1987-01-14 1993-09-16 Ciba-Geigy Ag Procedimiento para la obtencion de un sistema terapeutico peroral para productos activos dificilmente solubles.
SE8704097D0 (sv) * 1987-10-22 1987-10-22 Astra Ab Oral formulation of buspirone and salts thereof
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
IT1246382B (it) * 1990-04-17 1994-11-18 Eurand Int Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
JPH0624959A (ja) * 1991-10-04 1994-02-01 Bayer Yakuhin Kk 胃内浮遊型薬物徐放性固形製剤
TW209865B (es) 1992-01-10 1993-07-21 Bayer Ag
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IE75744B1 (en) * 1995-04-03 1997-09-24 Elan Corp Plc Controlled release biodegradable micro- and nanospheres containing cyclosporin
US5654005A (en) 1995-06-07 1997-08-05 Andrx Pharmaceuticals, Inc. Controlled release formulation having a preformed passageway
DE19546249A1 (de) * 1995-12-12 1997-06-19 Bayer Ag Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
US5874418A (en) * 1997-05-05 1999-02-23 Cydex, Inc. Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use

Also Published As

Publication number Publication date
CN1623533A (zh) 2005-06-08
CO5011082A1 (es) 2001-02-28
BG104256A (en) 2000-12-29
EP1017392B1 (de) 2002-07-17
EP1017392A1 (de) 2000-07-12
KR20010024269A (ko) 2001-03-26
CA2304135C (en) 2009-01-06
HK1032010A1 (en) 2001-07-06
WO1999015172A1 (de) 1999-04-01
PL192273B1 (pl) 2006-09-29
HUP0003840A2 (hu) 2001-04-28
CN1271281A (zh) 2000-10-25
DE59804823D1 (de) 2002-08-22
BR9812553B1 (pt) 2010-06-01
US6270799B1 (en) 2001-08-07
HUP0003840A3 (en) 2006-06-28
CA2304135A1 (en) 1999-04-01
TR200000752T2 (tr) 2000-09-21
PT1017392E (pt) 2002-10-31
IL134591A0 (en) 2001-04-30
GT199800152A (es) 2000-03-17
JP2010163455A (ja) 2010-07-29
ATE220547T1 (de) 2002-08-15
CZ293062B6 (cs) 2004-01-14
TW523412B (en) 2003-03-11
NZ503538A (en) 2001-03-30
ES2179533T3 (es) 2003-01-16
PE20000224A1 (es) 2000-05-11
SV1998000119A (es) 1999-03-02
MY129437A (en) 2007-04-30
PL339349A1 (en) 2000-12-18
NO327492B1 (no) 2009-07-20
NO20001375L (no) 2000-03-16
SK283462B6 (sk) 2003-08-05
SK4032000A3 (en) 2000-09-12
CN1178659C (zh) 2004-12-08
AR013967A1 (es) 2001-01-31
ZA988718B (en) 1999-04-01
AU731693B2 (en) 2001-04-05
UY25192A1 (es) 2001-08-27
AR065073A2 (es) 2009-05-13
BG64745B1 (bg) 2006-02-28
CN1895233A (zh) 2007-01-17
AR065072A2 (es) 2009-05-13
CZ20001076A3 (cs) 2000-07-12
KR100531065B1 (ko) 2005-11-28
ID24259A (id) 2000-07-13
HU226583B1 (hu) 2009-04-28
JP2001517625A (ja) 2001-10-09
DK1017392T3 (da) 2002-10-21
UA66812C2 (uk) 2004-06-15
HN1998000144A (es) 1999-06-02
BR9812553A (pt) 2000-07-25
NO20001375D0 (no) 2000-03-16
AU9348498A (en) 1999-04-12

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