SI0989851T1 - Self-emulsifying formulation for acidic lipophilic compounds - Google Patents

Self-emulsifying formulation for acidic lipophilic compounds

Info

Publication number
SI0989851T1
SI0989851T1 SI9830303T SI9830303T SI0989851T1 SI 0989851 T1 SI0989851 T1 SI 0989851T1 SI 9830303 T SI9830303 T SI 9830303T SI 9830303 T SI9830303 T SI 9830303T SI 0989851 T1 SI0989851 T1 SI 0989851T1
Authority
SI
Slovenia
Prior art keywords
self
pharmaceutically acceptable
emulsifying formulation
composition
lipophilic compounds
Prior art date
Application number
SI9830303T
Other languages
English (en)
Slovenian (sl)
Inventor
Walter Morozowich
Ping Gao
Original Assignee
Pharmacia & Upjohn Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Company filed Critical Pharmacia & Upjohn Company
Publication of SI0989851T1 publication Critical patent/SI0989851T1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Detergent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cosmetics (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
SI9830303T 1997-07-29 1998-07-27 Self-emulsifying formulation for acidic lipophilic compounds SI0989851T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5401297P 1997-07-29 1997-07-29
EP98936888A EP0989851B1 (en) 1997-07-29 1998-07-27 Self-emulsifying formulation for acidic lipophilic compounds
PCT/US1998/014817 WO1999006044A1 (en) 1997-07-29 1998-07-27 Pharmaceutical composition for acidic lipophilic compounds in a form of a self-emulsifying formulation

Publications (1)

Publication Number Publication Date
SI0989851T1 true SI0989851T1 (en) 2003-04-30

Family

ID=21988155

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9830303T SI0989851T1 (en) 1997-07-29 1998-07-27 Self-emulsifying formulation for acidic lipophilic compounds

Country Status (25)

Country Link
US (1) US6231887B1 (xx)
EP (1) EP0989851B1 (xx)
JP (1) JP4524367B2 (xx)
KR (1) KR100509131B1 (xx)
CN (1) CN1112927C (xx)
AT (1) ATE225174T1 (xx)
AU (1) AU728626B2 (xx)
BR (1) BR9810729B1 (xx)
CA (1) CA2294033C (xx)
CY (1) CY2006002I2 (xx)
CZ (1) CZ296957B6 (xx)
DE (1) DE69808463T2 (xx)
DK (1) DK0989851T3 (xx)
ES (1) ES2184310T3 (xx)
FI (1) FI20000172A (xx)
HK (1) HK1028879A1 (xx)
HU (1) HU228923B1 (xx)
NO (1) NO323425B1 (xx)
NZ (1) NZ502566A (xx)
PL (1) PL192865B1 (xx)
PT (1) PT989851E (xx)
RU (1) RU2202346C2 (xx)
SI (1) SI0989851T1 (xx)
SK (1) SK284616B6 (xx)
WO (1) WO1999006044A1 (xx)

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US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
JP4638053B2 (ja) * 1999-03-31 2011-02-23 ベーリンガー・インゲルハイム・インテルナツィオナール・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング レトロウイルスプロテアーゼインヒビター用医薬エマルジョン
US6956048B2 (en) 1999-03-31 2005-10-18 Pharmacia & Upjohn Company Pharmaceutical emulsions for retroviral protease inhibitors
SE0000774D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
SE0000773D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
WO2002036110A2 (en) * 2000-10-31 2002-05-10 Boehringer Ingelheim Pharmaceuticals, Inc. Oral self-emulsifying formulations of pyranone protease inhibitors
SE0102993D0 (sv) * 2001-09-07 2001-09-07 Astrazeneca Ab New self emulsifying drug delivery system
US20030165545A1 (en) * 2002-01-30 2003-09-04 Allergan, Inc. Ophthalmic compositions including oil-in-water emulsions, and methods for making and using same
CA2474838C (en) * 2002-02-01 2009-01-06 Pfizer Products Inc. Pharmaceutical compositions of amorphous dispersions of drugs and lipophilic microphase-forming materials
US6828301B2 (en) * 2002-02-07 2004-12-07 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for hepatitis C viral protease inhibitors
US20040191332A1 (en) * 2003-03-27 2004-09-30 Allergan, Inc. Preserved ophthalmic compositions
CA2520886A1 (en) 2003-04-02 2004-11-04 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for hepatitis c viral protease inhibitors
WO2005011635A2 (en) 2003-08-04 2005-02-10 Pfizer Products Inc. Pharmaceutical compositions of adsorbates of amorphous drugs and lipophilic microphase-forming materials
JP2007507226A (ja) * 2003-10-07 2007-03-29 イーライ リリー アンド カンパニー ラクトパミンの液状製剤
JP2008520701A (ja) * 2004-11-19 2008-06-19 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング チプラナビル及びレバーセットの同時投与を介したｈｉｖ感染症の治療方法
CA2586231A1 (en) * 2004-11-19 2006-05-26 Boehringer Ingelheim International Gmbh Method for treating hiv infection through co-administration of tipranavir and uk-427, 857
US20060142344A1 (en) * 2004-12-01 2006-06-29 Boehringer Ingelheim International Gmbh Method for treating HIV infection through co-administration of tipranavir and GW695634
JP5028885B2 (ja) * 2006-07-04 2012-09-19 大正製薬株式会社 ユビデカレノン含有自己乳化組成物
MX2009009850A (es) 2007-03-12 2009-09-24 Nektar Therapeutics Conjugados de inhibidor de oligomero-proteasa.
EP2262538B1 (en) * 2008-03-12 2014-12-10 Nektar Therapeutics Oligomer-amino acid conjugate
EP2440249A2 (en) 2009-06-12 2012-04-18 Nektar Therapeutics Covalent conjugates comprising a protease inhibitor, a water-soluble, non-peptidic oligomer and a lipophilic moiety
MY154683A (en) * 2009-07-07 2015-07-15 Boehringer Ingelheim Int Pharmaceutical composition for a hepatitis c viral protease inhibitor
ES2661812T3 (es) 2009-10-16 2018-04-04 Mochida Pharmaceutical Co., Ltd. Composiciones
RU2419426C1 (ru) * 2010-04-26 2011-05-27 Всеволод Иванович Киселев Лекарственное средство на основе дииндолилметана (dim) с повышенной биодоступностью и его использование в лечении гиперпластических и воспалительных заболеваний человека
CA2798180A1 (en) 2010-05-03 2011-11-10 Teikoku Pharma Usa, Inc. Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
AU2014204739B2 (en) * 2013-01-14 2016-08-11 Infirst Healthcare Limited Compositions and methods for treating severe pain

Family Cites Families (14)

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Publication number Priority date Publication date Assignee Title
US4230702A (en) 1978-01-09 1980-10-28 Kali-Chemie Pharma Gmbh Readily enterally absorbable pharmaceutical compositions of per se poorly enterally absorbable pharmacologically active agents
DE3300793A1 (de) * 1983-01-12 1984-07-12 Bayer Ag, 5090 Leverkusen Coccidiosemittel
GB8903804D0 (en) * 1989-02-20 1989-04-05 Sandoz Ltd Improvements in or relating to organic compounds
US5071643A (en) 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
IL102236A0 (en) * 1991-06-27 1993-01-14 Ltt Inst Co Ltd Topical preparations containing cyclosporin
GB9113872D0 (en) 1991-06-27 1991-08-14 Sandoz Ag Improvements in or relating to organic compounds
GB9208712D0 (en) * 1992-04-22 1992-06-10 Sandoz Ltd Pharmaceutical compositions containing cyclosporin derivates
US5376688A (en) 1992-12-18 1994-12-27 R. P. Scherer Corporation Enhanced solubility pharmaceutical solutions
IL129871A (en) * 1994-05-06 2003-11-23 Pharmacia & Upjohn Inc Process for preparing 4-phenyl-substituted octanoyl-oxazolidin-2-one intermediates that are useful for preparing pyran-2-ones useful for treating retroviral infections
CA2195623A1 (en) * 1994-07-22 1996-02-08 Rajeev D. Gokhale Self-emulsifying drug delivery system
WO1996033697A1 (fr) * 1995-04-24 1996-10-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Formulation auto-emulsionnable formant une emulsion huile dans l'eau
TR199701541T1 (xx) 1995-06-06 1998-03-21 F.Hoffmann-La Roche Ag Proteinaz engelleyici ve tekli gliserid i�eren farmas�tik bile�im.
ZA9710071B (en) * 1996-11-21 1998-05-25 Abbott Lab Pharmaceutical composition.

Also Published As

Publication number Publication date
PL192865B1 (pl) 2006-12-29
ES2184310T3 (es) 2003-04-01
NO20000466D0 (no) 2000-01-28
DE69808463T2 (de) 2003-06-26
CA2294033A1 (en) 1999-02-11
CA2294033C (en) 2007-01-09
BR9810729A (pt) 2000-08-08
KR100509131B1 (ko) 2005-08-18
FI20000172A (fi) 2000-01-28
RU2202346C2 (ru) 2003-04-20
US6231887B1 (en) 2001-05-15
ATE225174T1 (de) 2002-10-15
NO20000466L (no) 2000-03-28
JP2002510330A (ja) 2002-04-02
NZ502566A (en) 2002-03-28
CN1261796A (zh) 2000-08-02
AU8573898A (en) 1999-02-22
EP0989851B1 (en) 2002-10-02
DK0989851T3 (da) 2003-01-27
SK284616B6 (sk) 2005-07-01
HK1028879A1 (en) 2001-03-09
CY2006002I2 (el) 2012-01-25
EP0989851A1 (en) 2000-04-05
CN1112927C (zh) 2003-07-02
CZ296957B6 (cs) 2006-08-16
HUP0002440A2 (hu) 2001-09-28
PT989851E (pt) 2002-12-31
BR9810729B1 (pt) 2010-07-13
HU228923B1 (en) 2013-06-28
WO1999006044A1 (en) 1999-02-11
JP4524367B2 (ja) 2010-08-18
PL338335A1 (en) 2000-10-23
NO323425B1 (no) 2007-04-30
KR20010022369A (ko) 2001-03-15
HUP0002440A3 (en) 2001-10-29
AU728626B2 (en) 2001-01-11
DE69808463D1 (de) 2002-11-07
CZ2000156A3 (cs) 2000-05-17
CY2006002I1 (el) 2011-02-02
SK162000A3 (en) 2000-12-11

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