SI0810225T1 - Process for producing paroxetine - Google Patents

Process for producing paroxetine

Info

Publication number
SI0810225T1
SI0810225T1 SI9730144T SI9730144T SI0810225T1 SI 0810225 T1 SI0810225 T1 SI 0810225T1 SI 9730144 T SI9730144 T SI 9730144T SI 9730144 T SI9730144 T SI 9730144T SI 0810225 T1 SI0810225 T1 SI 0810225T1
Authority
SI
Slovenia
Prior art keywords
represented
general formula
alkoxycarbonylpiperidine
paroxetine
producing
Prior art date
Application number
SI9730144T
Other languages
English (en)
Inventor
Shu-Zhong Wang
Yasushi Matsumura
Original Assignee
Asahi Glass Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Glass Co Ltd filed Critical Asahi Glass Co Ltd
Publication of SI0810225T1 publication Critical patent/SI0810225T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
SI9730144T 1996-05-31 1997-06-02 Process for producing paroxetine SI0810225T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP13904896A JP3882224B2 (ja) 1996-05-31 1996-05-31 パロキセチンの製造方法
EP97108806A EP0810225B1 (en) 1996-05-31 1997-06-02 Process for producing paroxetine

Publications (1)

Publication Number Publication Date
SI0810225T1 true SI0810225T1 (en) 2001-10-31

Family

ID=15236260

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9730144T SI0810225T1 (en) 1996-05-31 1997-06-02 Process for producing paroxetine

Country Status (9)

Country Link
US (2) US6433179B1 (ja)
EP (1) EP0810225B1 (ja)
JP (1) JP3882224B2 (ja)
AT (1) ATE204870T1 (ja)
CA (1) CA2205770A1 (ja)
DE (1) DE69706366T2 (ja)
ES (1) ES2162156T3 (ja)
PT (1) PT810225E (ja)
SI (1) SI0810225T1 (ja)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3882224B2 (ja) * 1996-05-31 2007-02-14 旭硝子株式会社 パロキセチンの製造方法
EP1394160A1 (en) 1996-06-13 2004-03-03 SUMIKA FINE CHEMICALS Co., Ltd. Process for preparing crystalline paroxetin hydrochloride
EP0994872B9 (en) * 1997-06-10 2001-12-05 Synthon B.V. 4-phenylpiperidine compounds
CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
GB9828767D0 (en) * 1998-12-29 1999-02-17 Smithkline Beecham Plc Novel process
GB9914583D0 (en) * 1999-06-22 1999-08-25 Smithkline Beecham Plc Novel process
GB9916187D0 (en) * 1999-07-09 1999-09-08 Smithkline Beecham Plc Novel process
EP1280775A1 (en) 2000-05-12 2003-02-05 Synthon B.V. TOSYLATE SALTS OF 4-(p-FLUOROPHENYL)-PIPERIDINE-3-CARBINOLS
JP2004504319A (ja) * 2000-07-17 2004-02-12 スミスクライン　ビーチャム　パブリック　リミテッド　カンパニー ４−フェニルピペリジン誘導体の新規製造方法
US6777554B2 (en) 2001-02-05 2004-08-17 Teva Pharmaceutical Industries Ltd. Preparation of N-methylparoxetine and related intermediate compounds
NL1017421C2 (nl) * 2001-02-21 2002-01-15 Synthon Bv Werkwijze voor het vervaardigen van paroxetine.
JP2005524656A (ja) * 2002-02-22 2005-08-18 テバ ファーマシューティカル インダストリーズ リミティド 新規中間物質を用いるパロキセチンの調製
US6956121B2 (en) * 2002-03-01 2005-10-18 Teva Pharmaceutical Industries Ltd. Preparation of paroxetine involving novel intermediates
WO2006078470A2 (en) 2005-01-18 2006-07-27 Biocept, Inc. Cell separation using microchannel having patterned posts
US20090136982A1 (en) 2005-01-18 2009-05-28 Biocept, Inc. Cell separation using microchannel having patterned posts
WO2007015262A2 (en) * 2005-04-25 2007-02-08 Sun Pharmaceutical Industries Limited A process for the preparation of (-)-trans-4-(p-fluorophenyl)-3-[[3,4-(methylenedioxy)phenoxy]methyl)]piperidine
US20070112031A1 (en) * 2005-11-14 2007-05-17 Gant Thomas G Substituted phenylpiperidines with serotoninergic activity and enhanced therapeutic properties
US20080033050A1 (en) 2006-08-04 2008-02-07 Richards Patricia Allison Tewe Method of treating thermoregulatory disfunction with paroxetine
US9138430B2 (en) * 2007-12-27 2015-09-22 Mylan Specialty L.P. Formulation and method for the release of paroxetine in the large intestine
CN102718756B (zh) * 2012-07-02 2013-11-20 浙江尖峰药业有限公司 盐酸帕罗西汀化合物及其合成方法
CN104447714A (zh) * 2014-11-18 2015-03-25 成都医路康医学技术服务有限公司 一种盐酸帕罗西汀的生产工艺

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
US4268515A (en) * 1980-02-04 1981-05-19 Hoechst-Roussel Pharmaceuticals Inc. Spiro[dihydrobenzofuran-piperidines and-pyrrolidines], pharmaceutical compositions thereof and methods of use thereof
US4282233B1 (en) * 1980-06-19 2000-09-05 Schering Corp Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines
EP0190496A3 (en) 1984-12-13 1987-05-27 Beecham Group Plc Piperidine derivatives having a gastro-intestinal activity
EP0223403B1 (en) * 1985-10-25 1993-08-04 Beecham Group Plc Piperidine derivative, its preparation, and its use as medicament
US5227379A (en) 1986-11-03 1993-07-13 Novo Nordisk A/S Piperidine compounds and their preparation and use
IE66332B1 (en) 1986-11-03 1995-12-27 Novo Nordisk As Piperidine compounds and their preparation and use
IL101851A (en) * 1991-06-13 1996-05-14 Janssen Pharmaceutica Nv History 01 -) 4 - Pipridinyl - and Pipridinylidene (- Imidazo] A-1,2 [Pirolo, Thiano or Purano (] 3,2 [Azpin, their preparation and pharmaceutical preparations containing them and composition
JP2607784B2 (ja) 1991-09-30 1997-05-07 株式会社神戸製鋼所 廻し溶接用エンドタブ
SK283608B6 (sk) 1995-02-06 2003-10-07 Smithkline Beecham Plc Bezvodý hydrochlorid paroxetínu, spôsob jeho výroby a použitie
JP3882224B2 (ja) * 1996-05-31 2007-02-14 旭硝子株式会社 パロキセチンの製造方法
EP1394160A1 (en) 1996-06-13 2004-03-03 SUMIKA FINE CHEMICALS Co., Ltd. Process for preparing crystalline paroxetin hydrochloride
US5672612A (en) 1996-09-09 1997-09-30 Pentech Pharmaceuticals, Inc. Amorphous paroxetine composition
GB9817195D0 (en) * 1998-08-07 1998-10-07 Smithkline Beecham Plc Novel process

Also Published As

Publication number Publication date
US6433179B1 (en) 2002-08-13
CA2205770A1 (en) 1997-11-30
DE69706366D1 (de) 2001-10-04
US20020198387A1 (en) 2002-12-26
PT810225E (pt) 2001-12-28
ES2162156T3 (es) 2001-12-16
JP3882224B2 (ja) 2007-02-14
EP0810225A1 (en) 1997-12-03
EP0810225B1 (en) 2001-08-29
ATE204870T1 (de) 2001-09-15
DE69706366T2 (de) 2002-05-29
JPH09316072A (ja) 1997-12-09

Similar Documents

Publication Publication Date Title
SI0810225T1 (en) Process for producing paroxetine
TW254943B (ja)
DE3871190D1 (de) Polymerisationsverfahren und polymerisationskatalysator.
EP0989113A4 (en) METHOD FOR PRODUCING 2-AMINOMALONIC ACID DERIVATIVES AND 2-AMINO-1,3-PROPANEDIOL DERIVATIVES AND INTERMEDIATE PRODUCTS FOR PRODUCING THESE COMPOUNDS
EP0738703A3 (en) Acrylic acid derivatives, method for preparing the acrylic acid derivatives, and acrylic acid polymers
HU912884D0 (en) 1-methyl-carba-penem derivatives and method for producing them
EP0554455A4 (ja)
ES2010246A6 (es) Un compuesto.
ES2166021T3 (es) Procedimiento para la preparacion de 4-aril-3-hidroximetilpiperidinas.
WO1993009111A3 (en) Novel methods for the preparation of glycerol carbonate esters
ES2145920T3 (es) Procedimiento de produccion de derivado de alcoxiiminoacetamida.
DE69213184D1 (en) Phospholipase a2 inhibitor
TW326444B (en) An improved process for producing 4-hydroxy-2-pyrrolidone
EP1114812A4 (en) PROCESS FOR THE PREPARATION OF FLUOROUS BENZOIC ACIDS
ES2144327T3 (es) Procedimiento para preparar un compuesto de 2-cianobifenilo.
GB8907008D0 (en) Intermediates useful for the synthesis for delphinidin chloride
AU8310091A (en) Preparation of acylaminomethanephosphonic acids and acylaminomethanephosphinic acids
HU9200629D0 (en) Method for producing alpha-methylene-cyclopentanonne derivatives and preparatives containing said compounds
KR0137673B1 (en) Process for preparing sulfonamide derivative of norbornane
HUT70219A (en) 1-phenylpyrrolidone derivatives, intermediates for producing them and producing them
HU911528D0 (en) Process for producing dihydro-furanone derivatives
KR900009574A (ko) 1,4-가교된 시클로헥산 카르복실산 유도체의 제조방법
GR3035699T3 (en) Process for producing carboxylic acid derivative
KR970042488A (ko) 유기용매를 이용한 아크릴산 에스테르 유도체의 제조방법