SI0778025T1 - Use of 8,9-dehydroestrone for the manufacture of a medicament for the treatment of diseases caused by free radicals - Google Patents

Use of 8,9-dehydroestrone for the manufacture of a medicament for the treatment of diseases caused by free radicals

Info

Publication number
SI0778025T1
SI0778025T1 SI9630674T SI9630674T SI0778025T1 SI 0778025 T1 SI0778025 T1 SI 0778025T1 SI 9630674 T SI9630674 T SI 9630674T SI 9630674 T SI9630674 T SI 9630674T SI 0778025 T1 SI0778025 T1 SI 0778025T1
Authority
SI
Slovenia
Prior art keywords
dehydroestrone
medicament
manufacture
treatment
free radicals
Prior art date
Application number
SI9630674T
Other languages
English (en)
Slovenian (sl)
Inventor
Steven Jay Adelman
Original Assignee
Wyeth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth filed Critical Wyeth
Publication of SI0778025T1 publication Critical patent/SI0778025T1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/566—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
  • Transplantation (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
SI9630674T 1995-12-04 1996-11-28 Use of 8,9-dehydroestrone for the manufacture of a medicament for the treatment of diseases caused by free radicals SI0778025T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US793195P 1995-12-04 1995-12-04
EP96308632A EP0778025B1 (de) 1995-12-04 1996-11-28 Verwendung von 8,9-Dehydroestron zur Herstellung eines Arzneimittels zur Behandlung von durch freie Radikale verursachte Krankheiten

Publications (1)

Publication Number Publication Date
SI0778025T1 true SI0778025T1 (en) 2004-08-31

Family

ID=21728885

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9630674T SI0778025T1 (en) 1995-12-04 1996-11-28 Use of 8,9-dehydroestrone for the manufacture of a medicament for the treatment of diseases caused by free radicals

Country Status (23)

Country Link
EP (1) EP0778025B1 (de)
JP (1) JPH09169650A (de)
KR (1) KR100444002B1 (de)
CN (1) CN1104900C (de)
AR (2) AR005866A1 (de)
AT (1) ATE263565T1 (de)
AU (1) AU703814B2 (de)
BR (1) BR9605777A (de)
CA (1) CA2191835A1 (de)
CZ (1) CZ289780B6 (de)
DE (1) DE69632117T2 (de)
DK (1) DK0778025T3 (de)
ES (1) ES2215187T3 (de)
HK (1) HK1010095A1 (de)
HU (1) HUP9603329A3 (de)
IL (1) IL119744A (de)
MX (1) MX9606009A (de)
NO (1) NO312654B1 (de)
NZ (1) NZ299858A (de)
PT (1) PT778025E (de)
SI (1) SI0778025T1 (de)
SK (1) SK154296A3 (de)
ZA (1) ZA969923B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19723794A1 (de) * 1997-06-06 1998-12-10 Jenapharm Gmbh Nichtestrogene Derivate des Estradiols mit antioxidativer Aktivität
US7892751B2 (en) 2003-06-09 2011-02-22 Redox-Reactive Reagents Llc Method of detecting or diagnosing of a neurodegenerative disease or condition
CN1832756A (zh) * 2003-06-09 2006-09-13 约翰·A·麦金太尔 通过氧化还原反应改变血浆蛋白质结合专一性的方法
US9557325B2 (en) 2003-06-09 2017-01-31 Redox-Reactive Reagents Llc Method of altering the binding specificity of proteins by oxidation-reduction reactions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5210081A (en) * 1992-02-26 1993-05-11 American Home Products Corporation Alkali metal 8,9-dehydroestrone sulfate esters
DE4334823C2 (de) * 1993-10-09 1998-09-17 Schering Ag Verfahren zur Herstellung von Schwefelsäurehalbestern von Estrogenen
US5395831A (en) * 1994-04-08 1995-03-07 American Home Products Corporation Treating cardiac disorders with Δ9(11)-dehydro-8-isoestrone
DE19509729A1 (de) * 1995-03-13 1996-09-19 Schering Ag 17-Difluormethylen-Estratriene

Also Published As

Publication number Publication date
NO965165L (no) 1997-06-05
CN1104900C (zh) 2003-04-09
CZ289780B6 (cs) 2002-04-17
KR100444002B1 (ko) 2004-11-03
ZA969923B (en) 1998-05-26
KR970032870A (ko) 1997-07-22
HU9603329D0 (en) 1997-01-28
EP0778025A1 (de) 1997-06-11
NO312654B1 (no) 2002-06-17
DE69632117D1 (de) 2004-05-13
AU703814B2 (en) 1999-04-01
HUP9603329A2 (en) 1997-08-28
ES2215187T3 (es) 2004-10-01
IL119744A0 (en) 1997-03-18
DE69632117T2 (de) 2004-08-26
IL119744A (en) 2003-01-12
HUP9603329A3 (en) 1998-01-28
AU7194496A (en) 1997-06-12
EP0778025B1 (de) 2004-04-07
SK154296A3 (en) 1997-08-06
BR9605777A (pt) 1998-08-25
PT778025E (pt) 2004-08-31
CN1158725A (zh) 1997-09-10
NO965165D0 (no) 1996-12-03
NZ299858A (en) 2001-03-30
JPH09169650A (ja) 1997-06-30
CA2191835A1 (en) 1997-06-05
ATE263565T1 (de) 2004-04-15
AR005866A1 (es) 1999-07-21
CZ353296A3 (en) 1997-08-13
HK1010095A1 (en) 1999-06-11
DK0778025T3 (da) 2004-06-07
AR059965A2 (es) 2008-05-14
MX9606009A (es) 1997-08-30

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