SG50602A1 - Novel heterocyclic compound - Google Patents

Novel heterocyclic compound

Info

Publication number
SG50602A1
SG50602A1 SG1996006195A SG1996006195A SG50602A1 SG 50602 A1 SG50602 A1 SG 50602A1 SG 1996006195 A SG1996006195 A SG 1996006195A SG 1996006195 A SG1996006195 A SG 1996006195A SG 50602 A1 SG50602 A1 SG 50602A1
Authority
SG
Singapore
Prior art keywords
heterocyclic compound
novel heterocyclic
novel
substituted
hyperalgesic
Prior art date
Application number
SG1996006195A
Other languages
English (en)
Inventor
Knud Erik Anderson
Uff Bang Olsen
Petersen
Frederik Christian Gronvald
Ursula Sonnewald
Tine Krogh Jorgensen
Henrik Sune Andersen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of SG50602A1 publication Critical patent/SG50602A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Indole Compounds (AREA)
SG1996006195A 1994-01-04 1995-01-03 Novel heterocyclic compound SG50602A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK1994 1994-01-04
DK129094 1994-11-09

Publications (1)

Publication Number Publication Date
SG50602A1 true SG50602A1 (en) 1998-07-20

Family

ID=26063135

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996006195A SG50602A1 (en) 1994-01-04 1995-01-03 Novel heterocyclic compound

Country Status (31)

Country Link
US (8) US5595989A (enExample)
EP (1) EP0738262B1 (enExample)
JP (1) JP2944221B2 (enExample)
KR (1) KR100329450B1 (enExample)
CN (1) CN1083431C (enExample)
AT (1) ATE191909T1 (enExample)
AU (1) AU691858B2 (enExample)
BG (1) BG100692A (enExample)
BR (1) BR9506452A (enExample)
CA (1) CA2180238A1 (enExample)
CZ (1) CZ286109B6 (enExample)
DE (1) DE69516394T2 (enExample)
DK (1) DK0738262T3 (enExample)
ES (1) ES2147837T3 (enExample)
FI (1) FI114025B (enExample)
GR (1) GR3033967T3 (enExample)
HU (1) HUT75878A (enExample)
IL (1) IL112222A (enExample)
MY (1) MY113463A (enExample)
NO (1) NO306295B1 (enExample)
NZ (1) NZ277763A (enExample)
PE (1) PE45095A1 (enExample)
PL (1) PL180209B1 (enExample)
PT (1) PT738262E (enExample)
RU (1) RU2167152C2 (enExample)
SG (1) SG50602A1 (enExample)
SI (1) SI9520023A (enExample)
SK (1) SK88196A3 (enExample)
TW (1) TW300887B (enExample)
UA (1) UA47396C2 (enExample)
WO (1) WO1995018793A1 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
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US6239148B1 (en) 1994-01-04 2001-05-29 Novo Nordisk A/S N-substituted azaheterocyclic carboxylic acids and esters thereof
MY113463A (en) * 1994-01-04 2002-03-30 Novo Nordisk As Novel heterocyclic compounds
US6110913A (en) * 1994-01-04 2000-08-29 Novo Nordisk A/S N-substituted azaheterocyclic carboxylic acids and esters thereof
US5716949A (en) * 1995-04-07 1998-02-10 Novo Nordisk A/S Heterocyclic compounds
US5952352A (en) * 1995-04-07 1999-09-14 Novo Nordisk A/S Heterocyclic compounds
US5962449A (en) 1995-04-07 1999-10-05 Novo Nordisk A/S Tricyclic compounds in treating hyperalgesic conditions and NIDDM
UA54385C2 (uk) * 1995-04-07 2003-03-17 Ново Нордіск А/С N-заміщені азагетероциклічні карбонові кислоти та їх ефіри, спосіб їх одержання, фармацевтична композиція та спосіб лікування
US5698551A (en) * 1995-04-07 1997-12-16 Novo Nordisk A/S Heterocyclic compounds
KR20000064411A (ko) 1995-12-15 2000-11-06 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 새로운방법
US6323206B1 (en) 1996-07-12 2001-11-27 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
HUP0000088A3 (en) * 1996-10-04 2000-09-28 Novo Nordisk As N-substituted azaheterocyclic compounds, process for producing them and pharmaceutical compositions containing them
ZA978792B (en) * 1996-10-04 1998-04-06 Novo Nordisk As N-substituted azaheterocyclic compounds.
KR20000048899A (ko) * 1996-10-04 2000-07-25 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 1,4-디치환 피페라진
US6040318A (en) * 1997-06-25 2000-03-21 Novo Nordisk A/S Tricycle substituted with azaheterocyclic carboxylic acids
EP1049684A1 (en) 1997-10-27 2000-11-08 Dr. Reddy's Research Foundation Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them
CA2319077A1 (en) 1998-01-21 1999-07-29 Yoshisuke Nakasato Chemokine receptor antagonists and methods of use therefor
US6613905B1 (en) 1998-01-21 2003-09-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US6509346B2 (en) 1998-01-21 2003-01-21 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
JP2002501052A (ja) * 1998-01-21 2002-01-15 ミレニアム・ファーマシューティカルズ・インコーポレイテッド ケモカイン受容体アンタゴニストおよびその使用方法
ES2137136B1 (es) * 1998-05-18 2000-07-01 Esteve Labor Dr Empleo de derivados de aril (o heteroaril) azolilcarbinoles en la elaboracion de un medicamento para el tratamiento de la inflamacion neurogenica.
US7271176B2 (en) * 1998-09-04 2007-09-18 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use thereof
US6468996B1 (en) * 1998-10-21 2002-10-22 Novo Nordisk A/S Substituted hetero-polycyclic compounds as PPARα and PPARγ activators
EP1140084A1 (en) * 1998-12-22 2001-10-10 Novo Nordisk A/S Novel formulation
US6207682B1 (en) 1998-12-22 2001-03-27 Novo Nordisk A/S Modified release formulations containing (R)-1-(10,11-dihydro-5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1propyl)-3-piperidinecarboxylic acid
US7355042B2 (en) * 2001-10-16 2008-04-08 Hypnion, Inc. Treatment of CNS disorders using CNS target modulators
US7541365B2 (en) 2001-11-21 2009-06-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US20040087642A1 (en) * 2002-10-24 2004-05-06 Zeldis Jerome B. Methods of using and compositions comprising a JNK inhibitor for the treatment, prevention, management and/or modification of pain
TWI291467B (en) 2002-11-13 2007-12-21 Millennium Pharm Inc CCR1 antagonists and methods of use therefor
US20070066570A1 (en) * 2003-06-16 2007-03-22 Michael Solomon Methods for treating sleep disorders
AU2007290386A1 (en) 2006-09-01 2008-03-06 Immune Control, Inc. Novel compositions and methods for treatment of diseases related to activated lymphocytes
US10029995B2 (en) 2015-09-03 2018-07-24 Forma Therapeutics, Inc. [6,6] fused bicyclic HDAC8 inhibitors
EP3651751A4 (en) 2017-07-13 2021-03-31 Tonix Pharmaceuticals Holding Corp. CYCLOBENZAPRINE AND AMITRYPTILENE ANALOGUES
CN115850232B (zh) * 2023-02-16 2023-05-26 广州佳途科技股份有限公司 一种氟哌噻吨ep杂质h的制备方法及其应用

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MY113463A (en) * 1994-01-04 2002-03-30 Novo Nordisk As Novel heterocyclic compounds

Also Published As

Publication number Publication date
AU1311095A (en) 1995-08-01
AU691858B2 (en) 1998-05-28
US5595989A (en) 1997-01-21
EP0738262B1 (en) 2000-04-19
NZ277763A (en) 2001-11-30
DE69516394T2 (de) 2000-10-26
FI962749A0 (fi) 1996-07-04
HUT75878A (en) 1997-05-28
HU9601842D0 (en) 1996-09-30
EP0738262A1 (en) 1996-10-23
SI9520023A (en) 1997-04-30
US5712292A (en) 1998-01-27
ES2147837T3 (es) 2000-10-01
CZ192196A3 (en) 1997-05-14
CA2180238A1 (en) 1995-07-13
JP2944221B2 (ja) 1999-08-30
PL180209B1 (pl) 2001-01-31
US6043239A (en) 2000-03-28
JPH09507239A (ja) 1997-07-22
US5721254A (en) 1998-02-24
ATE191909T1 (de) 2000-05-15
TW300887B (enExample) 1997-03-21
NO962811L (no) 1996-09-04
UA47396C2 (uk) 2002-07-15
US5693649A (en) 1997-12-02
CN1142226A (zh) 1997-02-05
DK0738262T3 (da) 2000-09-04
RU2167152C2 (ru) 2001-05-20
IL112222A (en) 1999-12-31
SK88196A3 (en) 1997-06-04
BR9506452A (pt) 1997-09-02
FI962749L (fi) 1996-09-04
PT738262E (pt) 2000-10-31
GR3033967T3 (en) 2000-11-30
US5795888A (en) 1998-08-18
FI114025B (fi) 2004-07-30
BG100692A (en) 1997-09-30
KR100329450B1 (ko) 2002-10-04
CZ286109B6 (cs) 2000-01-12
NO306295B1 (no) 1999-10-18
DE69516394D1 (de) 2000-05-25
US5688788A (en) 1997-11-18
NO962811D0 (no) 1996-07-03
CN1083431C (zh) 2002-04-24
MY113463A (en) 2002-03-30
PE45095A1 (es) 1995-12-18
US5668129A (en) 1997-09-16
WO1995018793A1 (en) 1995-07-13
IL112222A0 (en) 1995-03-30

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