SG190140A1 - RABIES GLYCOPROTEIN VIRUS-LIKE PARTICLES (VLPs) - Google Patents

RABIES GLYCOPROTEIN VIRUS-LIKE PARTICLES (VLPs) Download PDF

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Publication number
SG190140A1
SG190140A1 SG2013034178A SG2013034178A SG190140A1 SG 190140 A1 SG190140 A1 SG 190140A1 SG 2013034178 A SG2013034178 A SG 2013034178A SG 2013034178 A SG2013034178 A SG 2013034178A SG 190140 A1 SG190140 A1 SG 190140A1
Authority
SG
Singapore
Prior art keywords
protein
vlp
proteins
vlps
cell
Prior art date
Application number
SG2013034178A
Other languages
English (en)
Inventor
Gale Smith
Ye Liu
Original Assignee
Novavax Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novavax Inc filed Critical Novavax Inc
Publication of SG190140A1 publication Critical patent/SG190140A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/205Rhabdoviridae, e.g. rabies virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20111Lyssavirus, e.g. rabies virus
    • C12N2760/20134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG2013034178A 2010-11-05 2011-11-07 RABIES GLYCOPROTEIN VIRUS-LIKE PARTICLES (VLPs) SG190140A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41076710P 2010-11-05 2010-11-05
PCT/US2011/059602 WO2012061815A2 (en) 2010-11-05 2011-11-07 RABIES GLYCOPROTEIN VIRUS-LIKE PARTICLES (VLPs)

Publications (1)

Publication Number Publication Date
SG190140A1 true SG190140A1 (en) 2013-06-28

Family

ID=46025156

Family Applications (1)

Application Number Title Priority Date Filing Date
SG2013034178A SG190140A1 (en) 2010-11-05 2011-11-07 RABIES GLYCOPROTEIN VIRUS-LIKE PARTICLES (VLPs)

Country Status (22)

Country Link
US (3) US9724405B2 (OSRAM)
EP (2) EP2635257B1 (OSRAM)
JP (2) JP6158088B2 (OSRAM)
KR (1) KR101847908B1 (OSRAM)
CN (2) CN103282023B (OSRAM)
AU (1) AU2011323090B2 (OSRAM)
BR (1) BR112013011194B1 (OSRAM)
CA (1) CA2817005C (OSRAM)
CY (1) CY1119284T1 (OSRAM)
DK (1) DK2635257T3 (OSRAM)
ES (1) ES2636965T3 (OSRAM)
HR (1) HRP20171213T1 (OSRAM)
HU (1) HUE034247T2 (OSRAM)
LT (1) LT2635257T (OSRAM)
MX (1) MX354750B (OSRAM)
PL (1) PL2635257T3 (OSRAM)
PT (1) PT2635257T (OSRAM)
RS (1) RS56157B1 (OSRAM)
SG (1) SG190140A1 (OSRAM)
SI (1) SI2635257T1 (OSRAM)
SM (1) SMT201700392T1 (OSRAM)
WO (1) WO2012061815A2 (OSRAM)

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KR102211077B1 (ko) * 2019-01-16 2021-02-02 충남대학교 산학협력단 바이러스 유사 입자를 이용한 슈도-타입 광견병 백신
WO2020154500A1 (en) 2019-01-23 2020-07-30 The Broad Institute, Inc. Supernegatively charged proteins and uses thereof
CN110007080B (zh) * 2019-04-12 2022-09-23 长春西诺生物科技有限公司 一种狂犬病毒抗体定量检测试剂盒及其制备方法与检测方法
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Also Published As

Publication number Publication date
MX354750B (es) 2018-03-20
US20190224307A1 (en) 2019-07-25
CN109157658A (zh) 2019-01-08
CA2817005A1 (en) 2012-05-10
BR112013011194B1 (pt) 2020-12-22
EP3246019A1 (en) 2017-11-22
JP6158088B2 (ja) 2017-07-05
DK2635257T3 (en) 2017-09-04
CY1119284T1 (el) 2018-02-14
CN103282023A (zh) 2013-09-04
US10086065B2 (en) 2018-10-02
LT2635257T (lt) 2017-09-25
WO2012061815A2 (en) 2012-05-10
EP3246019B1 (en) 2021-03-03
AU2011323090B2 (en) 2015-02-12
JP2017035093A (ja) 2017-02-16
JP2014500013A (ja) 2014-01-09
EP2635257B1 (en) 2017-07-05
JP6195965B2 (ja) 2017-09-13
US20140178419A1 (en) 2014-06-26
EP2635257A4 (en) 2014-04-02
PL2635257T3 (pl) 2017-10-31
BR112013011194A2 (pt) 2017-06-27
AU2011323090A1 (en) 2013-04-04
HRP20171213T1 (hr) 2017-10-20
CA2817005C (en) 2018-09-11
KR20130111581A (ko) 2013-10-10
SMT201700392T1 (it) 2017-09-07
ES2636965T3 (es) 2017-10-10
EP2635257A2 (en) 2013-09-11
RS56157B1 (sr) 2017-11-30
WO2012061815A3 (en) 2013-03-14
PT2635257T (pt) 2017-08-16
US9724405B2 (en) 2017-08-08
US20180021428A1 (en) 2018-01-25
CN103282023B (zh) 2018-09-21
MX2013005090A (es) 2013-10-25
SI2635257T1 (en) 2018-01-31
HUE034247T2 (en) 2018-02-28
RU2013125695A (ru) 2014-12-10
KR101847908B1 (ko) 2018-04-11

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