SG189950A1 - A collection and methods for its use - Google Patents
A collection and methods for its use Download PDFInfo
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- SG189950A1 SG189950A1 SG2013030085A SG2013030085A SG189950A1 SG 189950 A1 SG189950 A1 SG 189950A1 SG 2013030085 A SG2013030085 A SG 2013030085A SG 2013030085 A SG2013030085 A SG 2013030085A SG 189950 A1 SG189950 A1 SG 189950A1
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- G—PHYSICS
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/005—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
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- C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
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- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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| CN102993305B (zh) | 2012-11-16 | 2015-05-13 | 上海赛伦生物技术有限公司 | 人源抗人表皮生长因子受体抗体及其编码基因与应用 |
| PL3046412T3 (pl) * | 2013-09-18 | 2019-11-29 | Regeneron Pharma | Przekształcone histydyną łańcuchy lekkie przeciwciał i genetycznie zmodyfikowane zwierzęta inne niż człowiek do ich wytwarzania |
| WO2015089080A2 (en) | 2013-12-09 | 2015-06-18 | Adimab, Llc | Polyclonal mixtures of antibodies, and methods of making and using them |
| CA2935143C (en) * | 2013-12-27 | 2024-05-07 | Chugai Seiyaku Kabushiki Kaisha | Method for purifying antibody having low isoelectric point |
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| EP3443087B1 (en) * | 2016-04-12 | 2024-09-18 | Medimmune, LLC | Immune repertoire mining |
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| WO2019099454A2 (en) | 2017-11-15 | 2019-05-23 | Philippe Valadon | Highly functional antibody libraries |
| US11542329B2 (en) | 2018-05-16 | 2023-01-03 | Morphosys Ag | Antibodies targeting Glycoprotein VI |
| KR102115300B1 (ko) * | 2018-06-01 | 2020-05-26 | 재단법인 목암생명과학연구소 | 항체 라이브러리 및 이를 이용한 항체 스크리닝 방법 |
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| US20130236902A1 (en) | 2013-09-12 |
| DK2640742T3 (en) | 2018-12-03 |
| HRP20181811T1 (hr) | 2018-12-28 |
| IL226364B (en) | 2020-11-30 |
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| SG10201509257VA (en) | 2015-12-30 |
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| CA2816558A1 (en) | 2012-05-24 |
| MX353795B (es) | 2018-01-30 |
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| US9541559B2 (en) | 2017-01-10 |
| RU2013126025A (ru) | 2014-12-27 |
| ZA201303566B (en) | 2014-07-30 |
| US20120129717A1 (en) | 2012-05-24 |
| EP2640742B1 (en) | 2018-08-15 |
| JP6253986B2 (ja) | 2017-12-27 |
| AU2011331129A1 (en) | 2013-05-23 |
| KR101938021B1 (ko) | 2019-01-11 |
| CN103237809A (zh) | 2013-08-07 |
| IL226364A0 (en) | 2013-07-31 |
| AU2011331129B2 (en) | 2016-10-06 |
| US8367586B2 (en) | 2013-02-05 |
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| CN103237809B (zh) | 2016-09-07 |
| EP2640742A1 (en) | 2013-09-25 |
| KR20140015274A (ko) | 2014-02-06 |
| US20140206575A1 (en) | 2014-07-24 |
| PL2640742T3 (pl) | 2019-01-31 |
| WO2012066129A1 (en) | 2012-05-24 |
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