PL2640742T3 - Kolekcja sekwencji przeciwciał i jej zastosowanie - Google Patents
Kolekcja sekwencji przeciwciał i jej zastosowanieInfo
- Publication number
- PL2640742T3 PL2640742T3 PL11785411T PL11785411T PL2640742T3 PL 2640742 T3 PL2640742 T3 PL 2640742T3 PL 11785411 T PL11785411 T PL 11785411T PL 11785411 T PL11785411 T PL 11785411T PL 2640742 T3 PL2640742 T3 PL 2640742T3
- Authority
- PL
- Poland
- Prior art keywords
- collection
- antibody sequences
- antibody
- sequences
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/005—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
- C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41536710P | 2010-11-19 | 2010-11-19 | |
| EP10191910 | 2010-11-19 | ||
| US201161494452P | 2011-06-08 | 2011-06-08 | |
| EP11785411.7A EP2640742B1 (en) | 2010-11-19 | 2011-11-18 | A collection of antibody sequences its use |
| PCT/EP2011/070473 WO2012066129A1 (en) | 2010-11-19 | 2011-11-18 | A collection and methods for its use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2640742T3 true PL2640742T3 (pl) | 2019-01-31 |
Family
ID=44041472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL11785411T PL2640742T3 (pl) | 2010-11-19 | 2011-11-18 | Kolekcja sekwencji przeciwciał i jej zastosowanie |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US8367586B2 (enExample) |
| EP (1) | EP2640742B1 (enExample) |
| JP (1) | JP6253986B2 (enExample) |
| KR (1) | KR101938021B1 (enExample) |
| CN (1) | CN103237809B (enExample) |
| AU (1) | AU2011331129B2 (enExample) |
| CA (1) | CA2816558C (enExample) |
| DK (1) | DK2640742T3 (enExample) |
| ES (1) | ES2696548T3 (enExample) |
| HR (1) | HRP20181811T1 (enExample) |
| IL (1) | IL226364B (enExample) |
| MX (1) | MX353795B (enExample) |
| NZ (1) | NZ609707A (enExample) |
| PL (1) | PL2640742T3 (enExample) |
| RU (1) | RU2603080C2 (enExample) |
| SG (2) | SG189950A1 (enExample) |
| WO (1) | WO2012066129A1 (enExample) |
| ZA (1) | ZA201303566B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102993305B (zh) | 2012-11-16 | 2015-05-13 | 上海赛伦生物技术有限公司 | 人源抗人表皮生长因子受体抗体及其编码基因与应用 |
| KR102150414B1 (ko) * | 2013-09-18 | 2020-09-02 | 리제너론 파마슈티칼스 인코포레이티드 | 히스티딘 엔지니어링된 경쇄 항체 및 그것을 생성하기 위한 유전자 변형된 비-인간 동물 |
| US10684289B2 (en) | 2013-12-09 | 2020-06-16 | Adimab, Llc | Polyclonal mixtures of antibodies, and methods of making and using them |
| CN106029682B (zh) * | 2013-12-27 | 2021-04-13 | 中外制药株式会社 | 等电点低的抗体的纯化方法 |
| ES2877376T3 (es) | 2016-02-19 | 2021-11-16 | Morphosys Ag | Anticuerpos para IL-17C |
| JP7086856B2 (ja) * | 2016-04-12 | 2022-06-20 | メディミューン，エルエルシー | 免疫レパートリー発掘 |
| US11254734B2 (en) | 2016-11-14 | 2022-02-22 | Morphosys Ag | Fab molecules with a rodent hinge region and a non-rodent CH1 region |
| WO2019099454A2 (en) | 2017-11-15 | 2019-05-23 | Philippe Valadon | Highly functional antibody libraries |
| EP3793596A1 (en) | 2018-05-16 | 2021-03-24 | MorphoSys AG | Antibodies targeting glycoprotein vi |
| KR102115300B1 (ko) * | 2018-06-01 | 2020-05-26 | 재단법인 목암생명과학연구소 | 항체 라이브러리 및 이를 이용한 항체 스크리닝 방법 |
| AU2021274883A1 (en) | 2020-05-20 | 2022-12-01 | Centre National De La Recherche Scientifique - Cnrs - | Synthetic single domain library |
| EP4154004A1 (en) | 2020-06-08 | 2023-03-29 | Immundiagnostik AG | Improved method and test system for in-vitro determination of drug antibodies in blood |
| AU2021350342A1 (en) | 2020-09-24 | 2023-03-09 | Morphosys Ag | Novel human antibodies binding to human CD3 epsilon |
| AU2023240297A1 (en) | 2022-03-22 | 2024-10-03 | Morphosys Ag | Deimmunized antibodies specific for cd3 |
| WO2024236163A1 (en) | 2023-05-17 | 2024-11-21 | Morphosys Ag | T cell receptor beta constant region 2 (trbc2) antibodies |
| WO2025003511A1 (en) | 2023-06-30 | 2025-01-02 | Morphosys Ag | Dual-targeting of flt3 and cd123 co-expressing tumor cells by functional complementation of cycat® halfbody molecules |
| WO2025082777A1 (en) | 2023-10-17 | 2025-04-24 | Morphosys Ag | Dual-targeting of muc16 and mesothelin co-expressing tumor cells by functional complementation of cycat® halfbody molecules |
Family Cites Families (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5618920A (en) | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
| US5258498A (en) | 1987-05-21 | 1993-11-02 | Creative Biomolecules, Inc. | Polypeptide linkers for production of biosynthetic proteins |
| DE3853515T3 (de) | 1987-05-21 | 2005-08-25 | Micromet Ag | Multifunktionelle proteine mit vorbestimmter zielsetzung. |
| US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| EP1997891A1 (en) | 1988-09-02 | 2008-12-03 | Dyax Corporation | Generation and selection of recombinant varied binding proteins |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| WO1990005144A1 (en) | 1988-11-11 | 1990-05-17 | Medical Research Council | Single domain ligands, receptors comprising said ligands, methods for their production, and use of said ligands and receptors |
| FI915411A7 (fi) | 1989-05-16 | 1991-11-15 | Scripps Research Inst | Heteromeeristen reseptorien koe-ekspressio |
| CA2016841C (en) | 1989-05-16 | 1999-09-21 | William D. Huse | A method for producing polymers having a preselected activity |
| US6291159B1 (en) | 1989-05-16 | 2001-09-18 | Scripps Research Institute | Method for producing polymers having a preselected activity |
| US6291160B1 (en) | 1989-05-16 | 2001-09-18 | Scripps Research Institute | Method for producing polymers having a preselected activity |
| CA2016842A1 (en) | 1989-05-16 | 1990-11-16 | Richard A. Lerner | Method for tapping the immunological repertoire |
| US6291161B1 (en) | 1989-05-16 | 2001-09-18 | Scripps Research Institute | Method for tapping the immunological repertiore |
| US6291158B1 (en) | 1989-05-16 | 2001-09-18 | Scripps Research Institute | Method for tapping the immunological repertoire |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| WO1991010737A1 (en) | 1990-01-11 | 1991-07-25 | Molecular Affinities Corporation | Production of antibodies using gene libraries |
| US5780225A (en) | 1990-01-12 | 1998-07-14 | Stratagene | Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules |
| DE4002897A1 (de) | 1990-02-01 | 1991-08-08 | Behringwerke Ag | Herstellung und verwendung von genbanken synthetischer menschlicher antikoerper ("synthetische human-antikoerper-bibliotheken") |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| AU665190B2 (en) | 1990-07-10 | 1995-12-21 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| ATE439435T1 (de) | 1991-03-01 | 2009-08-15 | Dyax Corp | Chimäres protein mit mikroprotein mit zwei oder mehr disulfidbindungen und ausgestaltungen davon |
| WO1992015678A1 (en) | 1991-03-01 | 1992-09-17 | Stratagene | Pcr generated dicistronic dna molecules for producing antibodies |
| DK0597960T3 (da) | 1991-08-10 | 1999-09-13 | Medical Res Council | Behandling af cellepopulationer |
| JP3540315B2 (ja) | 1991-09-23 | 2004-07-07 | メディカル リサーチ カウンシル | キメラ抗体の製造−組合せアプローチ |
| US5565332A (en) | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| ATE408012T1 (de) | 1991-12-02 | 2008-09-15 | Medical Res Council | Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken |
| US5667988A (en) | 1992-01-27 | 1997-09-16 | The Scripps Research Institute | Methods for producing antibody libraries using universal or randomized immunoglobulin light chains |
| US5395750A (en) | 1992-02-28 | 1995-03-07 | Hoffmann-La Roche Inc. | Methods for producing proteins which bind to predetermined antigens |
| WO1993019172A1 (en) | 1992-03-24 | 1993-09-30 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| US5855885A (en) | 1993-01-22 | 1999-01-05 | Smith; Rodger | Isolation and production of catalytic antibodies using phage technology |
| AU8091694A (en) | 1993-10-26 | 1995-05-22 | United Biomedical Inc. | Structured synthetic antigen libraries as diagnostics, vaccines and therapeutics |
| US20010049107A1 (en) | 1994-01-31 | 2001-12-06 | Boston University | Polyclonal antibody libraries |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| EP2258726A1 (en) | 1995-06-14 | 2010-12-08 | The Regents of the University of California | High affinity human antibodies to c-erbB-2 |
| CA2229043C (en) * | 1995-08-18 | 2016-06-07 | Morphosys Gesellschaft Fur Proteinoptimierung Mbh | Protein/(poly)peptide libraries |
| US7264963B1 (en) | 1995-08-18 | 2007-09-04 | Morphosys Ag | Protein(poly)peptide libraries |
| GB9603507D0 (en) | 1996-02-20 | 1996-04-17 | Isis Innovation | Antibody variants |
| WO1999006587A2 (en) | 1997-08-01 | 1999-02-11 | Morphosys Ag | Novel method and phage for the identification of nucleic acid sequences encoding members of a multimeric (poly)peptide complex |
| GB9722131D0 (en) | 1997-10-20 | 1997-12-17 | Medical Res Council | Method |
| EP1157041B1 (en) | 1999-03-01 | 2005-06-01 | Genentech, Inc. | Antibodies for cancer therapy and diagnosis |
| EP1990409A3 (en) | 1999-07-20 | 2011-05-18 | MorphoSys AG | Bacteriophage |
| IL136459A0 (en) | 2000-05-30 | 2001-06-14 | Galim Galil Immunology Ltd | Antibody library |
| DE60144063D1 (de) | 2000-12-18 | 2011-03-31 | Dyax Corp | Gerichtete bibliotheken die genetisch verpackt sind |
| US7117096B2 (en) | 2001-04-17 | 2006-10-03 | Abmaxis, Inc. | Structure-based selection and affinity maturation of antibody library |
| ES2405551T3 (es) | 2001-10-01 | 2013-05-31 | Dyax Corporation | Vectores de presentación eucariotas multicatenarios y usos de los mismos |
| GB0130267D0 (en) | 2001-12-19 | 2002-02-06 | Neutec Pharma Plc | Focussed antibody technology |
| AU2002360068B2 (en) | 2001-12-21 | 2009-09-03 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Method for cloning of variable domain sequences |
| US7244592B2 (en) | 2002-03-07 | 2007-07-17 | Dyax Corp. | Ligand screening and discovery |
| AU2003253193B2 (en) | 2002-07-30 | 2009-07-02 | Morphosys Ag | Novel tricistronic vectors and uses therefor |
| US8557743B2 (en) | 2002-09-05 | 2013-10-15 | Dyax Corp. | Display library process |
| GB0309126D0 (en) | 2003-04-17 | 2003-05-28 | Neutec Pharma Plc | Clostridium difficile focussed antibodies |
| WO2005023993A2 (en) | 2003-09-09 | 2005-03-17 | Integrigen, Inc. | Methods and compositions for generation of germline human antibody genes |
| TWI333977B (en) | 2003-09-18 | 2010-12-01 | Symphogen As | Method for linking sequences of interest |
| CA2545512A1 (en) | 2003-11-12 | 2005-10-13 | Oncomab Gmbh | Methods of identifying neoplasm-specific antibodies and uses thereof |
| WO2005071112A2 (en) | 2004-01-26 | 2005-08-04 | Isis Innovation Ltd | Molecular analysis |
| US8399200B2 (en) | 2004-05-26 | 2013-03-19 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Isolation of allergen-specific immunoglobulin genes from human B-cells from atopy sufferers |
| WO2006014498A2 (en) | 2004-07-06 | 2006-02-09 | Bioren, Inc. | Universal antibody libraries |
| WO2006028987A2 (en) | 2004-09-02 | 2006-03-16 | Bioarray Solutions Ltd. | Nucleic acid amplification with integrated multiplex detection |
| US20060078898A1 (en) | 2004-10-12 | 2006-04-13 | Curry Bo U | Methods and compositions for reducing label variation in array-based comparative genome hybridization assays II |
| EP1848672A4 (en) | 2005-02-01 | 2009-11-04 | Morphosys Ag | LIBRARIES AND METHOD FOR ISOLATING ANTIBODIES |
| RU2311927C2 (ru) * | 2005-08-15 | 2007-12-10 | Федеральное государственное унитарное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека" | КОМБИНАТОРНАЯ ФАГМИДНАЯ БИБЛИОТЕКА ОДНОЦЕПОЧЕЧНЫХ АНТИТЕЛ ЧЕЛОВЕКА, ОБОГАЩЕННАЯ АНТИТЕЛАМИ ПРОТИВ ВИРУСА ОСПОВАКЦИНЫ, РЕКОМБИНАНТНАЯ ФАГМИДНАЯ ДНК pHEN-2A8, СОДЕРЖАЩАЯ УНИКАЛЬНЫЙ ГЕН ОДНОЦЕПОЧЕЧНОГО АНТИТЕЛА ЧЕЛОВЕКА, СПОСОБНОГО НЕЙТРАЛИЗОВАТЬ ВИРУС ОСПОВАКЦИНЫ И ВИРУС ОСПЫ КОРОВ, И ИСКУССТВЕННОЕ ОДНОЦЕПОЧЕЧНОЕ АНТИТЕЛО ЧЕЛОВЕКА 2A8, СПОСОБНОЕ НЕЙТРАЛИЗОВАТЬ ВИРУС ОСПОВАКЦИНЫ И ВИРУС ОСПЫ КОРОВ |
| EP2465870A1 (en) | 2005-11-07 | 2012-06-20 | Genentech, Inc. | Binding polypeptides with diversified and consensus VH/VL hypervariable sequences |
| AU2006350452B2 (en) | 2005-12-20 | 2012-10-25 | Morphosys Ag | Novel collection of HCDR3 regions and uses therefor |
| EP2420832A1 (en) | 2006-05-04 | 2012-02-22 | Abmaxis, Inc. | Cross-species and multi-species display systems |
| EP1918302A3 (en) * | 2006-05-18 | 2009-11-18 | AvantGen, Inc. | Methods for the identification and the isolation of epitope specific antibodies |
| KR20100089816A (ko) | 2007-08-21 | 2010-08-12 | 모르포시스 아게 | 이황화 결합을 형성하기 위한 개선된 방법 |
| CA2697193C (en) | 2007-09-14 | 2017-06-06 | Adimab, Inc. | Rationally designed, synthetic antibody libraries and uses therefor |
| ES2564523T3 (es) | 2007-12-19 | 2016-03-23 | Janssen Biotech, Inc. | Diseño y generación de bibliotecas de presentación en fago por pIX de novo humanas mediante fusión con pIX o pVII, vectores, anticuerpos y métodos |
| EP2088432A1 (en) * | 2008-02-11 | 2009-08-12 | MorphoSys AG | Methods for identification of an antibody or a target |
| EP2100970B1 (en) | 2008-03-13 | 2017-05-10 | National Institute of Immunology | Ig genes specific oligonucleotides and uses thereof |
| US9873957B2 (en) | 2008-03-13 | 2018-01-23 | Dyax Corp. | Libraries of genetic packages comprising novel HC CDR3 designs |
| EP2331570B1 (en) | 2008-09-10 | 2014-08-27 | Philochem AG | Display library for antibody selection |
| EP2356270B1 (en) | 2008-11-07 | 2016-08-24 | Fabrus Llc | Combinatorial antibody libraries and uses thereof |
| WO2010130824A2 (en) * | 2009-05-15 | 2010-11-18 | Morphosys Ag | Collections and uses thereof |
| NZ596603A (en) | 2009-05-29 | 2013-07-26 | Morphosys Ag | A collection of antibodies or fragments having properties relevant to developability |
| EP2528944B1 (en) | 2010-01-29 | 2015-08-12 | MorphoSys AG | Rodent combinatorial antibody libraries |
-
2011
- 2011-11-18 DK DK11785411.7T patent/DK2640742T3/en active
- 2011-11-18 SG SG2013030085A patent/SG189950A1/en unknown
- 2011-11-18 NZ NZ609707A patent/NZ609707A/en not_active IP Right Cessation
- 2011-11-18 EP EP11785411.7A patent/EP2640742B1/en active Active
- 2011-11-18 PL PL11785411T patent/PL2640742T3/pl unknown
- 2011-11-18 RU RU2013126025/10A patent/RU2603080C2/ru active
- 2011-11-18 JP JP2013539286A patent/JP6253986B2/ja active Active
- 2011-11-18 CN CN201180055462.8A patent/CN103237809B/zh active Active
- 2011-11-18 US US13/299,367 patent/US8367586B2/en active Active
- 2011-11-18 AU AU2011331129A patent/AU2011331129B2/en active Active
- 2011-11-18 CA CA2816558A patent/CA2816558C/en active Active
- 2011-11-18 US US13/884,975 patent/US8728981B2/en active Active
- 2011-11-18 MX MX2013005614A patent/MX353795B/es active IP Right Grant
- 2011-11-18 ES ES11785411T patent/ES2696548T3/es active Active
- 2011-11-18 HR HRP20181811TT patent/HRP20181811T1/hr unknown
- 2011-11-18 WO PCT/EP2011/070473 patent/WO2012066129A1/en not_active Ceased
- 2011-11-18 SG SG10201509257VA patent/SG10201509257VA/en unknown
- 2011-11-18 KR KR1020137015575A patent/KR101938021B1/ko active Active
-
2013
- 2013-05-16 ZA ZA2013/03566A patent/ZA201303566B/en unknown
- 2013-05-16 IL IL226364A patent/IL226364B/en active IP Right Grant
-
2014
- 2014-04-02 US US14/242,906 patent/US9541559B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US8728981B2 (en) | 2014-05-20 |
| KR101938021B1 (ko) | 2019-01-11 |
| US9541559B2 (en) | 2017-01-10 |
| JP2014500725A (ja) | 2014-01-16 |
| US20120129717A1 (en) | 2012-05-24 |
| AU2011331129B2 (en) | 2016-10-06 |
| IL226364B (en) | 2020-11-30 |
| NZ609707A (en) | 2014-12-24 |
| CN103237809A (zh) | 2013-08-07 |
| IL226364A0 (en) | 2013-07-31 |
| CA2816558C (en) | 2020-12-29 |
| MX353795B (es) | 2018-01-30 |
| RU2013126025A (ru) | 2014-12-27 |
| JP6253986B2 (ja) | 2017-12-27 |
| CN103237809B (zh) | 2016-09-07 |
| AU2011331129A1 (en) | 2013-05-23 |
| CA2816558A1 (en) | 2012-05-24 |
| EP2640742B1 (en) | 2018-08-15 |
| MX2013005614A (es) | 2013-11-21 |
| US20140206575A1 (en) | 2014-07-24 |
| RU2603080C2 (ru) | 2016-11-20 |
| DK2640742T3 (en) | 2018-12-03 |
| HRP20181811T1 (hr) | 2018-12-28 |
| ES2696548T3 (es) | 2019-01-16 |
| ZA201303566B (en) | 2014-07-30 |
| US20130236902A1 (en) | 2013-09-12 |
| WO2012066129A1 (en) | 2012-05-24 |
| US8367586B2 (en) | 2013-02-05 |
| SG189950A1 (en) | 2013-06-28 |
| KR20140015274A (ko) | 2014-02-06 |
| SG10201509257VA (en) | 2015-12-30 |
| EP2640742A1 (en) | 2013-09-25 |
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