SG186385A1 - Treatment of proliferative diseases - Google Patents

Treatment of proliferative diseases Download PDF

Info

Publication number
SG186385A1
SG186385A1 SG2012093050A SG2012093050A SG186385A1 SG 186385 A1 SG186385 A1 SG 186385A1 SG 2012093050 A SG2012093050 A SG 2012093050A SG 2012093050 A SG2012093050 A SG 2012093050A SG 186385 A1 SG186385 A1 SG 186385A1
Authority
SG
Singapore
Prior art keywords
seq
cancer
plant defensin
nad1
defensin
Prior art date
Application number
SG2012093050A
Other languages
English (en)
Inventor
Mark Darren Hulett
Ivan Ka Ho Poon
Marilyn Anne Anderson
Original Assignee
Balmoral Australia Pty Ltd
Hexima Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Balmoral Australia Pty Ltd, Hexima Ltd filed Critical Balmoral Australia Pty Ltd
Publication of SG186385A1 publication Critical patent/SG186385A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • G01N33/5017Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity for testing neoplastic activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/168Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/415Assays involving biological materials from specific organisms or of a specific nature from plants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
SG2012093050A 2010-06-24 2011-06-23 Treatment of proliferative diseases SG186385A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35812610P 2010-06-24 2010-06-24
PCT/AU2011/000760 WO2011160174A1 (en) 2010-06-24 2011-06-23 Treatment of proliferative diseases

Publications (1)

Publication Number Publication Date
SG186385A1 true SG186385A1 (en) 2013-01-30

Family

ID=45370753

Family Applications (1)

Application Number Title Priority Date Filing Date
SG2012093050A SG186385A1 (en) 2010-06-24 2011-06-23 Treatment of proliferative diseases

Country Status (12)

Country Link
US (1) US20120172313A1 (enExample)
EP (1) EP2585095A4 (enExample)
JP (1) JP2013530965A (enExample)
KR (1) KR20140003316A (enExample)
CN (1) CN103037888A (enExample)
AU (1) AU2011269726B2 (enExample)
CA (1) CA2803027A1 (enExample)
MX (1) MX2012014711A (enExample)
NZ (1) NZ603442A (enExample)
SG (1) SG186385A1 (enExample)
WO (1) WO2011160174A1 (enExample)
ZA (1) ZA201208389B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2673365B1 (en) 2011-02-07 2017-12-20 Hexima Limited Modified plant defensins useful as anti-pathogenic agents
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
WO2013039861A2 (en) * 2011-09-12 2013-03-21 modeRNA Therapeutics Engineered nucleic acids and methods of use thereof
EP2768849B1 (en) 2011-10-19 2017-09-27 Hexima Limited Novel plant defensins and use in the treatment of proliferative diseases
WO2016191790A1 (en) * 2015-05-29 2016-12-08 Hexima Limited A method of in vivo treatment
CN111751345A (zh) * 2020-07-08 2020-10-09 深圳海关动植物检验检疫技术中心 一种苜蓿黄萎病菌活性检测方法
KR102371762B1 (ko) * 2020-12-29 2022-03-07 중앙대학교 산학협력단 Brca1 매개 nsd2 유비퀴틴화를 통한 세포 분화 및 세포사멸 조절 용도

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002016423A2 (en) * 2000-08-25 2002-02-28 Basf Plant Science Gmbh PLANT POLYNUCLEOTIDES ENCODING NOVEL Na+/H+ ANTIPORTERS
CA2437606A1 (en) * 2001-02-08 2002-08-15 Marilyn Anne Anderson Plant-derived molecules and genetic sequences encoding same and uses therefor
US20070207209A1 (en) * 2004-08-27 2007-09-06 Murphy Christopher J Trophic factor combinations for nervous system treatment
CN104522032B (zh) * 2008-08-05 2017-01-18 赫希玛有限公司 植物抗病原体系统

Also Published As

Publication number Publication date
CA2803027A1 (en) 2011-12-29
US20120172313A1 (en) 2012-07-05
WO2011160174A1 (en) 2011-12-29
NZ603442A (en) 2013-09-27
ZA201208389B (en) 2013-06-26
EP2585095A4 (en) 2013-11-13
JP2013530965A (ja) 2013-08-01
AU2011269726A1 (en) 2012-11-29
KR20140003316A (ko) 2014-01-09
AU2011269726B2 (en) 2013-11-28
CN103037888A (zh) 2013-04-10
EP2585095A1 (en) 2013-05-01
MX2012014711A (es) 2013-03-21

Similar Documents

Publication Publication Date Title
AU2011269726B2 (en) Treatment of proliferative diseases
Petersen et al. Peanut defensins: Novel allergens isolated from lipophilic peanut extract
Lay et al. Defensins-components of the innate immune system in plants
FI110385B (fi) Menetelmä suvun Dermatofagoides proteiiniallergeenien eristetyn peptidin valmistamiseksi
Segura et al. Novel defensin subfamily from spinach (Spinacia oleracea)
Kim et al. In vitro activities of native and designed peptide antibiotics against drug sensitive and resistant tumor cell lines
Wang et al. Characterization of a desiccation-related protein in lily pollen during development and stress
Ravipati et al. Lysine-rich cyclotides: A new subclass of circular knotted proteins from violaceae
Palavalli et al. Imbibition of soybean seeds in warm water results in the release of copious amounts of Bowman–Birk protease inhibitor, a putative anticarcinogenic agent
Banerjee et al. IgE from latex-allergic patients binds to cloned and expressed B cell epitopes of prohevein
Ghosh et al. Primary identification, biochemical characterization, and immunologic properties of the allergenic pollen cyclophilin cat R 1
EP2768849B1 (en) Novel plant defensins and use in the treatment of proliferative diseases
PT1071767E (pt) Gene que codifica a heliomicina e a sua utilização
Montesinos et al. Antimicrobial peptides for plant disease control. From discovery to application
Zhang et al. A survey of the venom of the spider Lycosa vittata by biochemical, pharmacological and transcriptomic analyses
Bahk et al. Identification of crystallin family proteins in vitreous body in rat endotoxin‐induced uveitis: Involvement of crystallin truncation in uveitis pathogenesis
Ahmad et al. Characterization of anti-dengue and cytotoxic activity of protein hydrolysates from the exophytic bacteria of brown algae Sargassum sp
WO2008133929A2 (en) Cell permeable miniature proteins
TWI634210B (zh) 抑制熱休克蛋白質表現之胜肽及包含其之組成物
Kumari Discovery and application of cysteine-rich peptides from medicinal plants in drug development
Kaas et al. Antimicrobial peptides in plants.
CN115505574B (zh) 一种分泌抗CLas分泌蛋白R1g单克隆抗体的杂交瘤细胞株R1g1 4B4及应用
NZ622284B2 (en) Novel plant defensins and use in the treatment of proliferative diseases
Barkhuizen Mode of action studies of defensin peptides from native South African Brassicaceae species
Landi et al. Effects of indicitin, a novel ribosome-targeting enzyme from milky mushrooms, on four human cell lines and the gut microbiota