SG178795A1 - Blocking the migration or metastasis of cancer cells by affecting adhesion proteins and the uses of new compounds thereof - Google Patents

Blocking the migration or metastasis of cancer cells by affecting adhesion proteins and the uses of new compounds thereof Download PDF

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Publication number
SG178795A1
SG178795A1 SG2012011029A SG2012011029A SG178795A1 SG 178795 A1 SG178795 A1 SG 178795A1 SG 2012011029 A SG2012011029 A SG 2012011029A SG 2012011029 A SG2012011029 A SG 2012011029A SG 178795 A1 SG178795 A1 SG 178795A1
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SG
Singapore
Prior art keywords
cancer
angiopoietin
compound
benzoyl
angeloyl
Prior art date
Application number
SG2012011029A
Other languages
English (en)
Inventor
Pui-Kwong Chan
May Sung Mak
Original Assignee
Pacific Arrow Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/683,198 external-priority patent/US8614197B2/en
Priority claimed from PCT/US2007/077273 external-priority patent/WO2008028060A2/en
Application filed by Pacific Arrow Ltd filed Critical Pacific Arrow Ltd
Publication of SG178795A1 publication Critical patent/SG178795A1/en

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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/04Nitro compounds
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
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  • Heart & Thoracic Surgery (AREA)
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  • Oncology (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
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SG2012011029A 2007-02-16 2008-02-15 Blocking the migration or metastasis of cancer cells by affecting adhesion proteins and the uses of new compounds thereof SG178795A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US89038007P 2007-02-16 2007-02-16
US11/683,198 US8614197B2 (en) 2003-10-09 2007-03-07 Anti-tumor compounds with angeloyl groups
US94770507P 2007-07-03 2007-07-03
PCT/US2007/077273 WO2008028060A2 (en) 2006-09-01 2007-08-30 Anti-tumor compounds for inhibiting cancer growth

Publications (1)

Publication Number Publication Date
SG178795A1 true SG178795A1 (en) 2012-03-29

Family

ID=39925959

Family Applications (1)

Application Number Title Priority Date Filing Date
SG2012011029A SG178795A1 (en) 2007-02-16 2008-02-15 Blocking the migration or metastasis of cancer cells by affecting adhesion proteins and the uses of new compounds thereof

Country Status (7)

Country Link
EP (1) EP2121715A4 (de)
JP (1) JP2010519219A (de)
CN (1) CN101772511A (de)
AU (1) AU2008244648A1 (de)
CA (1) CA2676791A1 (de)
SG (1) SG178795A1 (de)
WO (1) WO2008133766A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7524824B2 (en) 2003-09-04 2009-04-28 Pacific Arrow Limited Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
US7727561B2 (en) 2001-08-31 2010-06-01 Pacific Arrow Limited Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
US7514412B2 (en) 2003-10-09 2009-04-07 Pacific Arrow Limited Anticancer biangeloyl saponins
US8614197B2 (en) 2003-10-09 2013-12-24 Pacific Arrow Limited Anti-tumor compounds with angeloyl groups
US7488753B2 (en) 2003-10-09 2009-02-10 Pacific Arrow Limited Composition comprising triterpene saponins and compounds with angeloyl functional group, methods for preparing same and uses thereof
US8586719B2 (en) 2005-04-27 2013-11-19 Pacific Arrow Limited Triterpenes for modulating gene expression and cell membrane, and as antiprotozoal agents
US20120277308A1 (en) 2010-07-16 2012-11-01 Pacific Arrow Limited compounds for treating cancer and other diseases
EP2593111B1 (de) * 2010-07-16 2017-09-27 Pacific Arrow Limited Neue verbindungen zur behandlung von krebs und anderen krankheiten
KR101398079B1 (ko) 2011-10-10 2014-05-27 재단법인 의약바이오컨버젼스연구단 글리실-티알엔에이 합성효소 및 캐드헤린을 이용한 암 예방 또는 치료제의 스크리닝 방법
KR101403019B1 (ko) 2013-02-25 2014-06-03 서울대학교산학협력단 폐암 진단용 마커
CA2903306A1 (en) * 2013-03-15 2014-09-18 Fundacio Institut De Recerca Biomedica (Irb Barcelona) Method for the diagnosis, prognosis and treatment of metastatic cancer
CN103235141A (zh) * 2013-04-27 2013-08-07 上海交通大学医学院附属新华医院 Atf3用于预测膀胱癌转移和判断预后的应用
JP6339814B2 (ja) * 2014-02-05 2018-06-06 株式会社島津製作所 がん転移マーカー及びその分析方法
CN104502603B (zh) * 2014-12-03 2016-04-06 上海交通大学医学院附属上海儿童医学中心 Myo1d作为诊断动脉导管闭合或开放的标志物
KR20170093182A (ko) 2014-12-11 2017-08-14 인바이오모션 에스.엘. 인간 c-maf에 대한 결합 구성원
CN105061545B (zh) * 2015-08-17 2018-01-30 中国人民解放军第二一〇医院 文冠果中三萜皂苷类化合物及其制备方法和应用
US10167293B2 (en) * 2016-05-26 2019-01-01 Bayer Pharma Aktiengesellschaft [8-(phenylsulfonyl)-3,8-diazabicyclo[3.2.1]oct-3-yl](1H-1,2,3-triazol-4-yl)methanones
CN106947821B (zh) * 2017-04-11 2020-06-30 成都望路医药技术有限公司 用于诊治结肠腺癌的生物标志物
CN108410986B (zh) * 2018-02-26 2021-06-22 中国人民解放军总医院 Cdh6促进骨肉瘤生长和转移
CN110272997B (zh) * 2018-03-14 2023-04-28 华中科技大学同济医学院附属同济医院 一种C/EBPβ基因或者蛋白的用途
KR102128331B1 (ko) * 2018-04-30 2020-06-30 인하대학교 산학협력단 Cdh13 또는 이를 코딩하는 유전자의 발현을 억제하는 제제를 포함하는, 방사선 치료로 인하여 노화된 혈관내피세포로 전이가 발생하는 암 전이 억제용 조성물
CN109970839B (zh) * 2019-04-16 2022-03-01 沈阳药科大学 三萜皂苷类化合物及其制备方法和医药用途
CN110672848A (zh) * 2019-10-25 2020-01-10 四川大学华西医院 Apeh自身抗体检测试剂在制备肺癌筛查试剂盒中的用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005037200A2 (en) * 2003-10-09 2005-04-28 Pacific Arrow Limited Composition comprising xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
US6616943B2 (en) * 2001-08-31 2003-09-09 Fountain Silver Limited Composition comprising Wenguanguo extracts and methods for preparing same
AU2005282437B2 (en) * 2004-09-07 2013-01-10 Pacific Arrow Limited Anti-tumor compounds with angeloyl groups
US7488753B2 (en) * 2003-10-09 2009-02-10 Pacific Arrow Limited Composition comprising triterpene saponins and compounds with angeloyl functional group, methods for preparing same and uses thereof
TWI454269B (zh) * 2003-12-23 2014-10-01 Pacific Arrow Ltd 由文冠果(xanthoceras sorbifolia)單離之化合物、其製備方法以及其用途
CN101553497B (zh) * 2006-09-01 2013-03-27 太平洋艾瑞有限公司 能抑止癌细胞生长的抗肿瘤化合物

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Publication number Publication date
CA2676791A1 (en) 2008-11-06
EP2121715A1 (de) 2009-11-25
EP2121715A4 (de) 2010-12-29
CN101772511A (zh) 2010-07-07
AU2008244648A1 (en) 2008-11-06
WO2008133766A1 (en) 2008-11-06
JP2010519219A (ja) 2010-06-03

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