EP2121715A4 - Blockierung der migration oder metastase von krebszellen durch anheftung von haftproteinen sowie anwendungen der daraus gewonnenen neuen verbindungen - Google Patents
Blockierung der migration oder metastase von krebszellen durch anheftung von haftproteinen sowie anwendungen der daraus gewonnenen neuen verbindungenInfo
- Publication number
- EP2121715A4 EP2121715A4 EP08725693A EP08725693A EP2121715A4 EP 2121715 A4 EP2121715 A4 EP 2121715A4 EP 08725693 A EP08725693 A EP 08725693A EP 08725693 A EP08725693 A EP 08725693A EP 2121715 A4 EP2121715 A4 EP 2121715A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- metastasis
- migration
- blocking
- cancer cells
- new compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
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- C07—ORGANIC CHEMISTRY
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- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
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- Organic Chemistry (AREA)
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- Psychiatry (AREA)
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- Biotechnology (AREA)
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Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US89038007P | 2007-02-16 | 2007-02-16 | |
US11/683,198 US8614197B2 (en) | 2003-10-09 | 2007-03-07 | Anti-tumor compounds with angeloyl groups |
US94770507P | 2007-07-03 | 2007-07-03 | |
PCT/US2007/077273 WO2008028060A2 (en) | 2006-09-01 | 2007-08-30 | Anti-tumor compounds for inhibiting cancer growth |
PCT/US2008/002086 WO2008133766A1 (en) | 2007-02-16 | 2008-02-15 | Blocking the migration or metastasis of cancer cells by affecting adhesion proteins and the uses of new compounds thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2121715A1 EP2121715A1 (de) | 2009-11-25 |
EP2121715A4 true EP2121715A4 (de) | 2010-12-29 |
Family
ID=39925959
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP08725693A Withdrawn EP2121715A4 (de) | 2007-02-16 | 2008-02-15 | Blockierung der migration oder metastase von krebszellen durch anheftung von haftproteinen sowie anwendungen der daraus gewonnenen neuen verbindungen |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP2121715A4 (de) |
JP (1) | JP2010519219A (de) |
CN (1) | CN101772511A (de) |
AU (1) | AU2008244648A1 (de) |
CA (1) | CA2676791A1 (de) |
SG (1) | SG178795A1 (de) |
WO (1) | WO2008133766A1 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7524824B2 (en) | 2003-09-04 | 2009-04-28 | Pacific Arrow Limited | Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof |
US7727561B2 (en) | 2001-08-31 | 2010-06-01 | Pacific Arrow Limited | Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof |
US8614197B2 (en) | 2003-10-09 | 2013-12-24 | Pacific Arrow Limited | Anti-tumor compounds with angeloyl groups |
US7514412B2 (en) | 2003-10-09 | 2009-04-07 | Pacific Arrow Limited | Anticancer biangeloyl saponins |
US7488753B2 (en) | 2003-10-09 | 2009-02-10 | Pacific Arrow Limited | Composition comprising triterpene saponins and compounds with angeloyl functional group, methods for preparing same and uses thereof |
US8586719B2 (en) | 2005-04-27 | 2013-11-19 | Pacific Arrow Limited | Triterpenes for modulating gene expression and cell membrane, and as antiprotozoal agents |
US20120277308A1 (en) | 2010-07-16 | 2012-11-01 | Pacific Arrow Limited | compounds for treating cancer and other diseases |
CN106905403B (zh) * | 2010-07-16 | 2020-10-23 | 太平洋艾瑞有限公司 | 可治疗癌症和其它疾病的新化合物 |
KR101398079B1 (ko) * | 2011-10-10 | 2014-05-27 | 재단법인 의약바이오컨버젼스연구단 | 글리실-티알엔에이 합성효소 및 캐드헤린을 이용한 암 예방 또는 치료제의 스크리닝 방법 |
KR101403019B1 (ko) | 2013-02-25 | 2014-06-03 | 서울대학교산학협력단 | 폐암 진단용 마커 |
KR20150122786A (ko) * | 2013-03-15 | 2015-11-02 | 펀다시오 인스티튜트 드 르세르카 바이오메디카 (아이알비 바르셀로나) | 암 전이의 진단, 예후 및 치료를 위한 방법 |
CN103235141A (zh) * | 2013-04-27 | 2013-08-07 | 上海交通大学医学院附属新华医院 | Atf3用于预测膀胱癌转移和判断预后的应用 |
JP6339814B2 (ja) * | 2014-02-05 | 2018-06-06 | 株式会社島津製作所 | がん転移マーカー及びその分析方法 |
CN104502603B (zh) * | 2014-12-03 | 2016-04-06 | 上海交通大学医学院附属上海儿童医学中心 | Myo1d作为诊断动脉导管闭合或开放的标志物 |
KR20170093182A (ko) | 2014-12-11 | 2017-08-14 | 인바이오모션 에스.엘. | 인간 c-maf에 대한 결합 구성원 |
CN105061545B (zh) * | 2015-08-17 | 2018-01-30 | 中国人民解放军第二一〇医院 | 文冠果中三萜皂苷类化合物及其制备方法和应用 |
US10167293B2 (en) * | 2016-05-26 | 2019-01-01 | Bayer Pharma Aktiengesellschaft | [8-(phenylsulfonyl)-3,8-diazabicyclo[3.2.1]oct-3-yl](1H-1,2,3-triazol-4-yl)methanones |
CN106947821B (zh) * | 2017-04-11 | 2020-06-30 | 成都望路医药技术有限公司 | 用于诊治结肠腺癌的生物标志物 |
CN108410986B (zh) * | 2018-02-26 | 2021-06-22 | 中国人民解放军总医院 | Cdh6促进骨肉瘤生长和转移 |
CN110272997B (zh) * | 2018-03-14 | 2023-04-28 | 华中科技大学同济医学院附属同济医院 | 一种C/EBPβ基因或者蛋白的用途 |
KR102128331B1 (ko) * | 2018-04-30 | 2020-06-30 | 인하대학교 산학협력단 | Cdh13 또는 이를 코딩하는 유전자의 발현을 억제하는 제제를 포함하는, 방사선 치료로 인하여 노화된 혈관내피세포로 전이가 발생하는 암 전이 억제용 조성물 |
CN109970839B (zh) * | 2019-04-16 | 2022-03-01 | 沈阳药科大学 | 三萜皂苷类化合物及其制备方法和医药用途 |
CN110672848A (zh) * | 2019-10-25 | 2020-01-10 | 四川大学华西医院 | Apeh自身抗体检测试剂在制备肺癌筛查试剂盒中的用途 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005037200A2 (en) * | 2003-10-09 | 2005-04-28 | Pacific Arrow Limited | Composition comprising xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof |
WO2005063273A1 (en) * | 2003-12-23 | 2005-07-14 | Pacific Arrow Limited | Composition comprising xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof |
WO2006029221A2 (en) * | 2004-09-07 | 2006-03-16 | Pacific Arrow Limited | Anti-tumor compounds with angeloyl groups |
WO2006116656A2 (en) * | 2005-04-27 | 2006-11-02 | Pacific Arrow Limited | Compositions comprising triterpene saponins and compounds with functional angeloyl groups for inhibition of venous insufficiency, leg swelling and tumors |
WO2008028060A2 (en) * | 2006-09-01 | 2008-03-06 | Pacific Arrow Limited | Anti-tumor compounds for inhibiting cancer growth |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6616943B2 (en) * | 2001-08-31 | 2003-09-09 | Fountain Silver Limited | Composition comprising Wenguanguo extracts and methods for preparing same |
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2008
- 2008-02-15 JP JP2009550096A patent/JP2010519219A/ja active Pending
- 2008-02-15 WO PCT/US2008/002086 patent/WO2008133766A1/en active Application Filing
- 2008-02-15 CN CN200880012065A patent/CN101772511A/zh active Pending
- 2008-02-15 SG SG2012011029A patent/SG178795A1/en unknown
- 2008-02-15 AU AU2008244648A patent/AU2008244648A1/en not_active Abandoned
- 2008-02-15 CA CA002676791A patent/CA2676791A1/en not_active Abandoned
- 2008-02-15 EP EP08725693A patent/EP2121715A4/de not_active Withdrawn
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005037200A2 (en) * | 2003-10-09 | 2005-04-28 | Pacific Arrow Limited | Composition comprising xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof |
WO2005063273A1 (en) * | 2003-12-23 | 2005-07-14 | Pacific Arrow Limited | Composition comprising xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof |
WO2006029221A2 (en) * | 2004-09-07 | 2006-03-16 | Pacific Arrow Limited | Anti-tumor compounds with angeloyl groups |
WO2006116656A2 (en) * | 2005-04-27 | 2006-11-02 | Pacific Arrow Limited | Compositions comprising triterpene saponins and compounds with functional angeloyl groups for inhibition of venous insufficiency, leg swelling and tumors |
WO2008028060A2 (en) * | 2006-09-01 | 2008-03-06 | Pacific Arrow Limited | Anti-tumor compounds for inhibiting cancer growth |
Non-Patent Citations (10)
Title |
---|
AHN KYUNG-SEOP ET AL: "Effects of oleanane-type triterpenoids from fabaceous plants on the expression of ICAM-1", BIOLOGICAL AND PHARMACEUTICAL BULLETIN, vol. 25, no. 8, August 2002 (2002-08-01), pages 1105 - 1107, XP002609400, ISSN: 0918-6158 * |
CHEMICAL AND PHARMACEUTICAL BULLETIN (TOKYO), vol. 48, no. 11, November 2000 (2000-11-01), pages 1711 - 1719, ISSN: 0009-2363 * |
CHINESE JOURNAL OF LUNG CANCER 200308 CN, vol. 6, no. 4, August 2003 (2003-08-01), pages 254 - 257, ISSN: 1009-3419 * |
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 2004, OVESNA Z ET AL: "Pentacyclic triterpenoic acids: new chemoprotective compounds", XP002609502, Database accession no. PREV200500050812 * |
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; November 2000 (2000-11-01), TEZUKA YASUHIRO ET AL: "Constituents of the Vietnamese medicinal plant Orthosiphon stamineus", XP002609401, Database accession no. PREV200100067220 * |
DATABASE EMBASE [online] ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL; August 2003 (2003-08-01), HUANG W ET AL: "Study on anti-invasive effect and apoptosis induction of pentacyclic triterpenoid in human lung cancer cells", XP002609399, Database accession no. EMB-2003347021 * |
KONOSHIMA T ET AL: "ANTITUMOR AGENTS 82. CYTOTOXIC SAPOGENOLS FROM AESCULUS-HIPPOCASTANUM", JOURNAL OF NATURAL PRODUCTS, AMERICAN CHEMICAL SOCIETY, US, vol. 49, no. 4, 1 July 1986 (1986-07-01), pages 650 - 656, XP002510554, ISSN: 0163-3864, DOI: 10.1021/NP50046A015 * |
NEOPLASMA (BRATISLAVA), vol. 51, no. 5, 2004, pages 327 - 333, ISSN: 0028-2685 * |
See also references of WO2008133766A1 * |
VOUTQUENNE L ET AL: "Haemolytic acylated triterpenoid saponins from Harpullia austro-caledonica", PHYTOCHEMISTRY, PERGAMON PRESS, GB, vol. 66, no. 7, 1 April 2005 (2005-04-01), pages 825 - 835, XP004846755, ISSN: 0031-9422, DOI: 10.1016/J.PHYTOCHEM.2005.02.009 * |
Also Published As
Publication number | Publication date |
---|---|
AU2008244648A1 (en) | 2008-11-06 |
EP2121715A1 (de) | 2009-11-25 |
CA2676791A1 (en) | 2008-11-06 |
SG178795A1 (en) | 2012-03-29 |
CN101772511A (zh) | 2010-07-07 |
JP2010519219A (ja) | 2010-06-03 |
WO2008133766A1 (en) | 2008-11-06 |
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