SG177895A1 - Secretion of antibodies without signal peptides from bacteria - Google Patents
Secretion of antibodies without signal peptides from bacteria Download PDFInfo
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- SG177895A1 SG177895A1 SG2011092400A SG2011092400A SG177895A1 SG 177895 A1 SG177895 A1 SG 177895A1 SG 2011092400 A SG2011092400 A SG 2011092400A SG 2011092400 A SG2011092400 A SG 2011092400A SG 177895 A1 SG177895 A1 SG 177895A1
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- antibody
- antibodies
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1214—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
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US70190205P | 2005-07-22 | 2005-07-22 | |
US11/273,906 US8211648B2 (en) | 2005-07-22 | 2005-11-14 | Secretion of antibodies without signal peptides from bacteria |
Publications (1)
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SG177895A1 true SG177895A1 (en) | 2012-02-28 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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SG2011092400A SG177895A1 (en) | 2005-07-22 | 2006-07-07 | Secretion of antibodies without signal peptides from bacteria |
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US (2) | US8211648B2 (de) |
EP (1) | EP1907610B1 (de) |
JP (1) | JP5087541B2 (de) |
KR (1) | KR101014891B1 (de) |
CN (1) | CN101568647B (de) |
AU (1) | AU2006276823B2 (de) |
CA (1) | CA2615776C (de) |
HK (1) | HK1113393A1 (de) |
IL (1) | IL188889A (de) |
NZ (1) | NZ565126A (de) |
SG (1) | SG177895A1 (de) |
WO (1) | WO2007018853A2 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8211648B2 (en) * | 2005-07-22 | 2012-07-03 | Kalobios Pharmaceuticals, Inc. | Secretion of antibodies without signal peptides from bacteria |
JO3076B1 (ar) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
JP5688363B2 (ja) | 2008-04-28 | 2015-03-25 | カロバイオス ファーマシューティカルズ インコーポレイティッド | 顆粒球−マクロファージコロニー刺激因子に対する抗体 |
JP2012516897A (ja) | 2009-02-04 | 2012-07-26 | カロバイオス ファーマシューティカルズ インコーポレイティッド | シュードモナス・エルギノーサ(PseudomonasAeruginosa)感染の治療のための抗生物質と抗体療法との組み合わせ |
WO2010093814A1 (en) | 2009-02-11 | 2010-08-19 | Kalobios Pharmaceuticals, Inc. | Methods of treating dementia using a gm-csf antagonist |
JP2013508292A (ja) | 2009-10-14 | 2013-03-07 | カロバイオス ファーマシューティカルズ インコーポレイティッド | EphA3に対する抗体 |
AR079336A1 (es) | 2009-12-11 | 2012-01-18 | Irm Llc | Antagonistas de la pro-proteina convertasa-subtilisina/quexina tipo 9 (pcsk9) |
KR20140006022A (ko) | 2011-02-11 | 2014-01-15 | 아이알엠 엘엘씨 | Pcsk9 길항제 |
WO2012133119A1 (ja) * | 2011-03-28 | 2012-10-04 | 長瀬産業株式会社 | フェリチンの製造方法 |
WO2012168491A1 (en) | 2011-06-10 | 2012-12-13 | Novartis Ag | Pharmaceutical formulations of pcsk9 antagonists |
WO2012170607A2 (en) | 2011-06-10 | 2012-12-13 | Novartis Ag | Use of pcsk9 antagonists |
JP6415987B2 (ja) * | 2012-03-02 | 2018-10-31 | アブリンクス エン.ヴェー. | シュードモナス・エルギノーサのPcrVに結合する単一可変ドメイン抗体 |
WO2014084859A1 (en) | 2012-11-30 | 2014-06-05 | Novartis Ag | Molecules and methods for modulating tmem16a activities |
BR112015017560A2 (pt) * | 2013-01-24 | 2018-05-15 | Scripps Korea Antibody Institute | biblioteca de fv à base de combinação de proteína e modo de preparação da mesma |
JP5924795B2 (ja) * | 2014-06-13 | 2016-05-25 | テンボロン オイ | 複合体 |
RU2609627C2 (ru) * | 2014-09-26 | 2017-02-02 | Закрытое Акционерное Общество "Биокад" | Высокоаффинные и агрегационно стабильные антитела на основе вариабельных доменов vl и производного vhh |
MA41044A (fr) | 2014-10-08 | 2017-08-15 | Novartis Ag | Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer |
CA3011359A1 (en) * | 2016-01-13 | 2017-07-20 | Regeneron Pharmaceuticals, Inc. | Rodents having an engineered heavy chain diversity region |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US5618920A (en) * | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
US5576184A (en) * | 1988-09-06 | 1996-11-19 | Xoma Corporation | Production of chimeric mouse-human antibodies with specificity to human tumor antigens |
AU643189B2 (en) | 1988-09-06 | 1993-11-11 | Xoma Corporation | Production of chimeric mouse-human antibodies with specificity to human tumor antigens |
AU627591B2 (en) | 1989-06-19 | 1992-08-27 | Xoma Corporation | Chimeric mouse-human km10 antibody with specificity to a human tumor cell antigen |
US5733743A (en) * | 1992-03-24 | 1998-03-31 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
US5563046A (en) * | 1993-08-02 | 1996-10-08 | Celtrix Pharmaceuticals, Inc. | Fusion polypeptides and proteins |
US5914254A (en) * | 1993-08-02 | 1999-06-22 | Celtrix Pharmaceuticals, Inc. | Expression of fusion polypeptides transported out of the cytoplasm without leader sequences |
JPH07289267A (ja) * | 1994-04-25 | 1995-11-07 | Oriental Yeast Co Ltd | 発現増強方法 |
JPH09313191A (ja) | 1996-03-28 | 1997-12-09 | Mitsui Petrochem Ind Ltd | 蛋白質の分泌生産法 |
US5824502A (en) * | 1996-03-28 | 1998-10-20 | Mitsui Chemicals, Inc. | Method for secretory production of protein |
EP1157041B1 (de) * | 1999-03-01 | 2005-06-01 | Genentech, Inc. | Antikörper zur krebsbehandlung und -diagnose |
WO2005019819A1 (en) * | 2003-08-20 | 2005-03-03 | Biosite, Inc. | Methods and compositions for measuring biologically active natriuretic peptides and for improving their therapeutic potential |
US7425328B2 (en) * | 2003-04-22 | 2008-09-16 | Purdue Pharma L.P. | Tissue factor antibodies and uses thereof |
DE10325026B4 (de) | 2003-06-02 | 2013-04-18 | Genencor International,Inc. | Bakterien mit erhöhter Proteinsekretion, Nukleotidsequenzen codierend für ein SecA Protein mit erhöhter Proteinsekretion sowie Verfahren zur Produktion von Proteinen |
US20040266993A1 (en) | 2003-06-30 | 2004-12-30 | Evans Glen A. | Non-immunoglobulin binding polypeptides |
WO2005069970A2 (en) * | 2004-01-20 | 2005-08-04 | Kalobios, Inc. | Antibody specificity transfer using minimal essential binding determinants |
US8211648B2 (en) * | 2005-07-22 | 2012-07-03 | Kalobios Pharmaceuticals, Inc. | Secretion of antibodies without signal peptides from bacteria |
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2006
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- 2006-07-07 WO PCT/US2006/026334 patent/WO2007018853A2/en active Application Filing
- 2006-07-07 EP EP06786474.4A patent/EP1907610B1/de not_active Not-in-force
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- 2006-07-07 JP JP2008522802A patent/JP5087541B2/ja not_active Expired - Fee Related
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- 2006-07-07 CA CA2615776A patent/CA2615776C/en not_active Expired - Fee Related
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2012
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Also Published As
Publication number | Publication date |
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US20120309055A1 (en) | 2012-12-06 |
CN101568647B (zh) | 2012-10-03 |
JP5087541B2 (ja) | 2012-12-05 |
NZ565126A (en) | 2011-03-31 |
EP1907610A4 (de) | 2009-12-23 |
WO2007018853A2 (en) | 2007-02-15 |
KR101014891B1 (ko) | 2011-02-15 |
JP2009510998A (ja) | 2009-03-19 |
CA2615776A1 (en) | 2007-02-15 |
EP1907610B1 (de) | 2013-09-11 |
KR20080031452A (ko) | 2008-04-08 |
CN101568647A (zh) | 2009-10-28 |
IL188889A (en) | 2014-09-30 |
US9127046B2 (en) | 2015-09-08 |
WO2007018853A3 (en) | 2009-04-16 |
AU2006276823A1 (en) | 2007-02-15 |
HK1113393A1 (en) | 2008-10-03 |
US8211648B2 (en) | 2012-07-03 |
IL188889A0 (en) | 2008-04-13 |
US20070020685A1 (en) | 2007-01-25 |
AU2006276823B2 (en) | 2010-04-22 |
CA2615776C (en) | 2014-05-13 |
EP1907610A2 (de) | 2008-04-09 |
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