SG165344A1 - Method for treating vasculitis - Google Patents
Method for treating vasculitisInfo
- Publication number
- SG165344A1 SG165344A1 SG201006432-7A SG2010064327A SG165344A1 SG 165344 A1 SG165344 A1 SG 165344A1 SG 2010064327 A SG2010064327 A SG 2010064327A SG 165344 A1 SG165344 A1 SG 165344A1
- Authority
- SG
- Singapore
- Prior art keywords
- antibody
- associated vasculitis
- binds
- treating
- treatment
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 206010047115 Vasculitis Diseases 0.000 title abstract 2
- 208000002267 Anti-neutrophil cytoplasmic antibody-associated vasculitis Diseases 0.000 abstract 2
- 210000003719 b-lymphocyte Anatomy 0.000 abstract 2
- 239000002458 cell surface marker Substances 0.000 abstract 2
- 102100022005 B-lymphocyte antigen CD20 Human genes 0.000 abstract 1
- 101000897405 Homo sapiens B-lymphocyte antigen CD20 Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000001086 cytosolic effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/72—Increased effector function due to an Fc-modification
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Genetics & Genomics (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61610404P | 2004-10-05 | 2004-10-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG165344A1 true SG165344A1 (en) | 2010-10-28 |
Family
ID=36148785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG201006432-7A SG165344A1 (en) | 2004-10-05 | 2005-09-28 | Method for treating vasculitis |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US20060110387A1 (enExample) |
| EP (1) | EP1812060A2 (enExample) |
| JP (1) | JP2008515890A (enExample) |
| KR (1) | KR20070100228A (enExample) |
| CN (1) | CN101087807A (enExample) |
| AR (1) | AR052219A1 (enExample) |
| AU (1) | AU2005294666A1 (enExample) |
| BR (1) | BRPI0516297A (enExample) |
| CA (1) | CA2580271A1 (enExample) |
| GT (1) | GT200500276A (enExample) |
| IL (1) | IL181922A0 (enExample) |
| NO (1) | NO20072312L (enExample) |
| PA (1) | PA8647601A1 (enExample) |
| PE (1) | PE20060934A1 (enExample) |
| RU (1) | RU2411956C2 (enExample) |
| SG (1) | SG165344A1 (enExample) |
| SV (1) | SV2006002256A (enExample) |
| TW (1) | TW200628169A (enExample) |
| WO (1) | WO2006041680A2 (enExample) |
| ZA (2) | ZA200702335B (enExample) |
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| AU777970C (en) | 1999-05-07 | 2006-08-17 | F. Hoffman-La Roche Ag | Treatment of autoimmune diseases with antagonists which bind to B cell surface markers |
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| JP4653109B2 (ja) | 2003-11-05 | 2011-03-16 | ロシュ グリクアート アクチェンゲゼルシャフト | 高められたFcレセプター結合親和性及びエフェクター機能をもつCD20抗体 |
| SG10201403526YA (en) | 2005-07-25 | 2014-10-30 | Emergent Product Dev Seattle | B-cell reduction using cd37-specific and cd20-specific binding molecules |
| EP1878747A1 (en) | 2006-07-11 | 2008-01-16 | greenovation Biotech GmbH | Glyco-engineered antibodies |
| EP2178916B1 (en) * | 2007-07-31 | 2014-12-17 | Regeneron Pharmaceuticals, Inc. | Human antibodies to human cd20 and method of using thereof |
| ES2368700T3 (es) | 2008-04-11 | 2011-11-21 | Emergent Product Development Seattle, Llc | Agente inmunoterapéutico para cd37 y combinación con un agente quimioterapéutico bifuncional del mismo. |
| JPWO2010021385A1 (ja) * | 2008-08-22 | 2012-01-26 | 持田製薬株式会社 | Anca関連血管炎治療薬 |
| TW201438738A (zh) | 2008-09-16 | 2014-10-16 | 建南德克公司 | 治療進展型多發性硬化症之方法 |
| WO2010075249A2 (en) | 2008-12-22 | 2010-07-01 | Genentech, Inc. | A method for treating rheumatoid arthritis with b-cell antagonists |
| WO2011028945A1 (en) | 2009-09-03 | 2011-03-10 | Genentech, Inc. | Methods for treating, diagnosing, and monitoring rheumatoid arthritis |
| AR078161A1 (es) * | 2009-09-11 | 2011-10-19 | Hoffmann La Roche | Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento. |
| AU2011215900A1 (en) | 2010-02-10 | 2012-07-26 | Immunogen, Inc. | CD20 antibodies and uses thereof |
| EP2582373A4 (en) | 2010-06-16 | 2013-10-30 | Bruce Chandler May | USE OF LEVOCETIRIZIN AND MONTELUKAST IN THE TREATMENT OF INFLUENZA, COLLECTIONS AND INFLAMMATION |
| RU2013140975A (ru) | 2011-02-28 | 2015-04-10 | Дженентек, Инк. | Биологические маркеры и способы прогнозирования восприимчивости к антагонистам в-клеток |
| JOP20200236A1 (ar) | 2012-09-21 | 2017-06-16 | Regeneron Pharma | الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها |
| WO2014164285A2 (en) | 2013-03-13 | 2014-10-09 | Inflammatory Response Research, Inc. | Use of levocetirizine and montelukast in the treatment of vasculitis |
| ES2660494T3 (es) | 2013-03-13 | 2018-03-22 | 14779507 | Uso de levocetirizina y montelukast en el tratamiento de una lesión traumática |
| CA2901421A1 (en) | 2013-03-13 | 2014-10-09 | Bruce Chandler May | Use of levocetirizine and montelukast in the treatment of autoimmune disorders |
| TWI701042B (zh) | 2014-03-19 | 2020-08-11 | 美商再生元醫藥公司 | 用於腫瘤治療之方法及抗體組成物 |
| CA2947508A1 (en) * | 2014-06-26 | 2015-12-30 | Xigen Inflammation Ltd. | New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
| EP3193875B1 (en) | 2014-09-15 | 2022-02-16 | Inflammatory Response Research, Inc. | Levocetirizine and montelukast in the treatment of inflammation mediated conditions |
| SMT202000438T1 (it) | 2014-11-17 | 2020-09-10 | Regeneron Pharma | Metodi per trattamento di tumore usando l'anticorpo bispecifico cd3xcd20 |
| CN105688208A (zh) * | 2016-03-04 | 2016-06-22 | 刘文霞 | 一种用于治疗视网膜血管炎的复方颗粒及其制备方法 |
| WO2018071524A1 (en) * | 2016-10-11 | 2018-04-19 | The University Of North Carolina At Chapel Hill | Gene-specific dna methylation changes predict relapse/remission in anca-associated vasculitis patients |
| CA3089240A1 (en) * | 2018-02-07 | 2019-08-15 | Insmed Incorporated | Certain (2s)-n-[(1s)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides for treating anca associated vasculitides |
| US11819520B2 (en) | 2018-02-23 | 2023-11-21 | Duke University | Cultured thymus tissue transplantation promotes donor-specific tolerance to allogeneic solid organ transplants |
| US12364715B2 (en) | 2018-02-23 | 2025-07-22 | Enzyvant Therapeutics Gmbh | Methods of determining the suitability of cultured thymus tissue for implantation into humans and associated methods of use |
| MX2020008590A (es) | 2018-02-23 | 2020-09-21 | Duke Univ & Medical Center | El trasplante de tejido de timo cultivado promueve la tolerancia especifica de donante a los trasplantes alogenicos de organos solidos. |
| LT3844189T (lt) | 2018-08-31 | 2025-02-25 | Regeneron Pharmaceuticals, Inc. | Cd3/cd20 bispecifinių antikūnų dozavimo strategija, mažinanti citokinų išsiskyrimo sindromą |
| EP3669888B1 (en) * | 2018-12-20 | 2025-09-24 | Gambro Lundia AB | Extracorporeal devices for methods for treating diseases associated with anti-neutrophil cytoplasmic antibodies |
| TW202525323A (zh) * | 2023-07-06 | 2025-07-01 | 大陸商榮昌生物製藥(煙臺)股份有限公司 | 用TACI-Fc融合蛋白治療ANCA相關性血管炎的方法 |
| CN119322175A (zh) * | 2024-10-18 | 2025-01-17 | 武汉塞力斯生物技术有限公司 | 一种血管炎抗体联检试剂盒 |
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-
2005
- 2005-09-28 JP JP2007535709A patent/JP2008515890A/ja active Pending
- 2005-09-28 US US11/238,281 patent/US20060110387A1/en not_active Abandoned
- 2005-09-28 WO PCT/US2005/034647 patent/WO2006041680A2/en not_active Ceased
- 2005-09-28 CA CA002580271A patent/CA2580271A1/en not_active Abandoned
- 2005-09-28 RU RU2007116980/15A patent/RU2411956C2/ru not_active IP Right Cessation
- 2005-09-28 AU AU2005294666A patent/AU2005294666A1/en not_active Abandoned
- 2005-09-28 CN CNA2005800417165A patent/CN101087807A/zh active Pending
- 2005-09-28 EP EP05810224A patent/EP1812060A2/en not_active Withdrawn
- 2005-09-28 BR BRPI0516297-1A patent/BRPI0516297A/pt not_active IP Right Cessation
- 2005-09-28 KR KR1020077007778A patent/KR20070100228A/ko not_active Ceased
- 2005-09-28 SG SG201006432-7A patent/SG165344A1/en unknown
- 2005-09-28 ZA ZA200702335A patent/ZA200702335B/xx unknown
- 2005-10-04 PA PA20058647601A patent/PA8647601A1/es unknown
- 2005-10-05 GT GT200500276A patent/GT200500276A/es unknown
- 2005-10-05 SV SV2005002256A patent/SV2006002256A/es unknown
- 2005-10-05 TW TW094134821A patent/TW200628169A/zh unknown
- 2005-10-05 AR ARP050104207A patent/AR052219A1/es not_active Application Discontinuation
- 2005-10-05 PE PE2005001180A patent/PE20060934A1/es not_active Application Discontinuation
-
2006
- 2006-09-28 US US11/536,571 patent/US20070025987A1/en not_active Abandoned
-
2007
- 2007-03-14 IL IL181922A patent/IL181922A0/en unknown
- 2007-05-04 NO NO20072312A patent/NO20072312L/no not_active Application Discontinuation
-
2008
- 2008-05-20 ZA ZA200804339A patent/ZA200804339B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20072312L (no) | 2007-07-05 |
| CN101087807A (zh) | 2007-12-12 |
| WO2006041680A3 (en) | 2007-08-23 |
| RU2007116980A (ru) | 2008-11-20 |
| RU2411956C2 (ru) | 2011-02-20 |
| JP2008515890A (ja) | 2008-05-15 |
| AR052219A1 (es) | 2007-03-07 |
| US20060110387A1 (en) | 2006-05-25 |
| CA2580271A1 (en) | 2006-04-20 |
| EP1812060A2 (en) | 2007-08-01 |
| US20070025987A1 (en) | 2007-02-01 |
| AU2005294666A1 (en) | 2006-04-20 |
| WO2006041680A2 (en) | 2006-04-20 |
| ZA200702335B (en) | 2009-05-27 |
| GT200500276A (es) | 2006-05-08 |
| PE20060934A1 (es) | 2006-10-11 |
| ZA200804339B (en) | 2010-03-31 |
| BRPI0516297A (pt) | 2008-09-02 |
| PA8647601A1 (es) | 2007-01-17 |
| SV2006002256A (es) | 2006-04-20 |
| TW200628169A (en) | 2006-08-16 |
| KR20070100228A (ko) | 2007-10-10 |
| IL181922A0 (en) | 2008-04-13 |
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