SG157225A1 - Process for the manufacture of organic compounds - Google Patents
Process for the manufacture of organic compoundsInfo
- Publication number
- SG157225A1 SG157225A1 SG200605092-6A SG2006050926A SG157225A1 SG 157225 A1 SG157225 A1 SG 157225A1 SG 2006050926 A SG2006050926 A SG 2006050926A SG 157225 A1 SG157225 A1 SG 157225A1
- Authority
- SG
- Singapore
- Prior art keywords
- manufacture
- organic compounds
- dihydroxyester
- ketoester
- hydroxy
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000002894 organic compounds Chemical class 0.000 title 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 2
- -1 alkali metal salt Chemical class 0.000 abstract 2
- LCKIEQZJEYYRIY-UHFFFAOYSA-N Titanium ion Chemical compound [Ti+4] LCKIEQZJEYYRIY-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- SSVSTIGWSOEKDK-UHFFFAOYSA-N methoxyborane Chemical compound BOC SSVSTIGWSOEKDK-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Cephalosporin Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35231602P | 2002-01-28 | 2002-01-28 | |
| US38318802P | 2002-05-24 | 2002-05-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG157225A1 true SG157225A1 (en) | 2009-12-29 |
Family
ID=27669055
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG200605092-6A SG157225A1 (en) | 2002-01-28 | 2003-01-27 | Process for the manufacture of organic compounds |
| SG200605094-2A SG161742A1 (en) | 2002-01-28 | 2003-01-27 | Process for the manufacture of organic compounds |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG200605094-2A SG161742A1 (en) | 2002-01-28 | 2003-01-27 | Process for the manufacture of organic compounds |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US6835838B2 (enExample) |
| EP (1) | EP1472227B1 (enExample) |
| JP (1) | JP2005516064A (enExample) |
| KR (2) | KR20040077883A (enExample) |
| CN (2) | CN100378081C (enExample) |
| AU (4) | AU2003239294B2 (enExample) |
| BR (1) | BR0307236A (enExample) |
| CA (1) | CA2472340A1 (enExample) |
| CO (1) | CO5601045A2 (enExample) |
| EC (1) | ECSP045202A (enExample) |
| IL (1) | IL162817A0 (enExample) |
| MX (1) | MXPA04007308A (enExample) |
| NO (1) | NO327363B1 (enExample) |
| NZ (3) | NZ554366A (enExample) |
| PL (1) | PL371383A1 (enExample) |
| RU (1) | RU2360903C2 (enExample) |
| SG (2) | SG157225A1 (enExample) |
| WO (1) | WO2003064382A2 (enExample) |
| ZA (1) | ZA200405239B (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04000322A (es) | 2001-07-13 | 2005-09-08 | Astrazeneca Uk Ltd | Preparacion de compuestos de aminopirimidina. |
| CN1288136C (zh) * | 2001-11-14 | 2006-12-06 | 日产化学工业株式会社 | 光学活性氧代庚烯酸酯的制备方法 |
| DE60326819D1 (de) * | 2002-01-31 | 2009-05-07 | Novartis Ag | Verfahren zur herstellung von inhibitoren der hmg-coa-reduktase |
| CN100349871C (zh) * | 2002-09-20 | 2007-11-21 | 日产化学工业株式会社 | 制备3,5－二羟基－6－庚烯酸酯的方法 |
| CN101219992B (zh) * | 2003-02-12 | 2011-08-31 | 日产化学工业株式会社 | 匹伐他汀钙的晶形 |
| US7851624B2 (en) * | 2003-12-24 | 2010-12-14 | Teva Pharamaceutical Industries Ltd. | Triol form of rosuvastatin and synthesis of rosuvastatin |
| TWI328006B (en) * | 2003-12-26 | 2010-08-01 | Nissan Chemical Ind Ltd | Crystal form of quinoline compound and process for its production |
| CN1763015B (zh) * | 2004-10-22 | 2011-06-22 | 四川抗菌素工业研究所有限公司 | 一种罗舒伐他汀及其药用盐的制备方法及中间体 |
| GB0428328D0 (en) | 2004-12-24 | 2005-02-02 | Astrazeneca Uk Ltd | Chemical process |
| GB0514078D0 (en) * | 2005-07-08 | 2005-08-17 | Astrazeneca Uk Ltd | Chemical process |
| US8455640B2 (en) * | 2006-05-03 | 2013-06-04 | Msn Laboratories Limited | Process for statins and its pharmaceutically acceptable salts thereof |
| US8404841B2 (en) * | 2006-10-09 | 2013-03-26 | Msn Laboratories Limited | Process for the preparation of statins and their pharmaceutically acceptable salts thereof |
| TW200831469A (en) * | 2006-12-01 | 2008-08-01 | Astrazeneca Uk Ltd | Chemical process |
| EP2387561A4 (en) * | 2009-01-19 | 2012-07-25 | Msn Lab Ltd | IMPROVED PROCESS FOR THE PREPARATION OF HIGH-PURITY (3R, 5S) -7-β-CYCLOPROPYL-4- (4-FLUOROPHENYL) QUINOLIN-3-YL-3,5-DIHYDROXY-6 (E) -HEPTENOIC ACID, INCLUDING ITS PHARMACEUTICALLY ACCEPTABLE SALTS |
| RU2425034C1 (ru) * | 2010-01-11 | 2011-07-27 | Государственное образовательное учреждение высшего профессионального образования "Кубанский государственный технологический университет" (ГОУ ВПО "КубГТУ") | Способ получения производных (e)-4-(6,7-диметокси-2-метил-3-хинолил)-3-бутен-2-она |
| EP2526099B1 (en) | 2010-01-18 | 2016-03-30 | MSN Laboratories Limited | Improved process for the preparation of amide intermediates and their use thereof |
| EP2423195A1 (en) | 2010-07-26 | 2012-02-29 | LEK Pharmaceuticals d.d. | Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof |
| US9034901B2 (en) | 2010-08-25 | 2015-05-19 | Cadila Healthcare Limited | Pitavastatin calcium and process for its preparation |
| EP2638013A4 (en) * | 2010-11-12 | 2014-03-26 | Hetero Research Foundation | NEW POLYMORPHS OF CALCIUM PIVASTATIN |
| WO2012140490A2 (en) | 2011-04-11 | 2012-10-18 | Aurobindo Pharma Limited | Process for preparing quinoline derivative |
| CN103755568B (zh) * | 2013-12-10 | 2015-10-28 | 江西科技师范大学 | IeodomycinA和B立体选择性合成方法 |
| CN107949556B (zh) | 2015-08-05 | 2021-12-07 | 株式会社Api | 生产匹伐他汀钙的方法 |
| CN108976168B (zh) * | 2017-06-02 | 2020-09-25 | 浙江京新药业股份有限公司 | 一种匹伐他汀半钙盐晶型及其制备方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0520406A1 (en) * | 1991-06-24 | 1992-12-30 | Nissan Chemical Industries Ltd. | Diastereomer salt of optically active quinolinemevalonic acid |
| EP0521471A1 (en) * | 1991-07-01 | 1993-01-07 | Shionogi Seiyaku Kabushiki Kaisha | Pyrimidine derivatives as HMG-CoA reductase inhibitors |
| WO2008096257A1 (en) * | 2007-02-08 | 2008-08-14 | Aurobindo Pharma Limited | An improved process for preparation of rosuvastatin calcium |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4906624A (en) * | 1987-09-08 | 1990-03-06 | Warner-Lambert Company | 6-(((Substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
| NZ230121A (en) * | 1988-08-29 | 1993-08-26 | Squibb & Sons Inc | Pyridine and quinoline terminal groups for hmg-coenzyme a reductase inhibitors and pharmaceutical compositions for lowering blood serum cholesterol levels |
| JP3130342B2 (ja) * | 1991-10-04 | 2001-01-31 | 日産化学工業株式会社 | 動脈硬化性血管内膜肥厚抑制薬 |
| JP3554036B2 (ja) * | 1994-09-06 | 2004-08-11 | 宇部興産株式会社 | 光学活性な７−置換キノリル−３，５−ジヒドロキシ−ヘプト−６−エン酸エステル誘導体の製造方法 |
| CN1288136C (zh) * | 2001-11-14 | 2006-12-06 | 日产化学工业株式会社 | 光学活性氧代庚烯酸酯的制备方法 |
-
2003
- 2003-01-24 US US10/350,615 patent/US6835838B2/en not_active Expired - Lifetime
- 2003-01-27 CN CNB200510005170XA patent/CN100378081C/zh not_active Expired - Lifetime
- 2003-01-27 NZ NZ554366A patent/NZ554366A/en not_active IP Right Cessation
- 2003-01-27 WO PCT/EP2003/000804 patent/WO2003064382A2/en not_active Ceased
- 2003-01-27 SG SG200605092-6A patent/SG157225A1/en unknown
- 2003-01-27 KR KR10-2004-7011572A patent/KR20040077883A/ko not_active Ceased
- 2003-01-27 KR KR1020107017248A patent/KR20100091267A/ko not_active Ceased
- 2003-01-27 PL PL03371383A patent/PL371383A1/xx unknown
- 2003-01-27 BR BR0307236-3A patent/BR0307236A/pt not_active Application Discontinuation
- 2003-01-27 NZ NZ554367A patent/NZ554367A/en not_active IP Right Cessation
- 2003-01-27 EP EP03734696.2A patent/EP1472227B1/en not_active Expired - Lifetime
- 2003-01-27 CN CNA038028778A patent/CN1625550A/zh active Pending
- 2003-01-27 JP JP2003564005A patent/JP2005516064A/ja active Pending
- 2003-01-27 MX MXPA04007308A patent/MXPA04007308A/es active IP Right Grant
- 2003-01-27 IL IL16281703A patent/IL162817A0/xx unknown
- 2003-01-27 CA CA002472340A patent/CA2472340A1/en not_active Abandoned
- 2003-01-27 NZ NZ534136A patent/NZ534136A/en not_active IP Right Cessation
- 2003-01-27 RU RU2004126448/04A patent/RU2360903C2/ru not_active IP Right Cessation
- 2003-01-27 SG SG200605094-2A patent/SG161742A1/en unknown
- 2003-01-27 AU AU2003239294A patent/AU2003239294B2/en not_active Ceased
-
2004
- 2004-07-01 ZA ZA2004/05239A patent/ZA200405239B/en unknown
- 2004-07-14 US US10/891,357 patent/US7572917B2/en not_active Expired - Fee Related
- 2004-07-22 EC EC2004005202A patent/ECSP045202A/es unknown
- 2004-08-06 CO CO04076720A patent/CO5601045A2/es not_active Application Discontinuation
- 2004-08-27 NO NO20043586A patent/NO327363B1/no not_active IP Right Cessation
-
2006
- 2006-10-03 AU AU2006225206A patent/AU2006225206B2/en not_active Ceased
- 2006-10-03 AU AU2006225205A patent/AU2006225205B2/en not_active Ceased
-
2009
- 2009-07-02 US US12/497,001 patent/US20090299065A1/en not_active Abandoned
- 2009-08-12 AU AU2009208129A patent/AU2009208129A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0520406A1 (en) * | 1991-06-24 | 1992-12-30 | Nissan Chemical Industries Ltd. | Diastereomer salt of optically active quinolinemevalonic acid |
| EP0521471A1 (en) * | 1991-07-01 | 1993-01-07 | Shionogi Seiyaku Kabushiki Kaisha | Pyrimidine derivatives as HMG-CoA reductase inhibitors |
| WO2008096257A1 (en) * | 2007-02-08 | 2008-08-14 | Aurobindo Pharma Limited | An improved process for preparation of rosuvastatin calcium |
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