RU2360903C2 - Способ получения органических соединений - Google Patents
Способ получения органических соединений Download PDFInfo
- Publication number
- RU2360903C2 RU2360903C2 RU2004126448/04A RU2004126448A RU2360903C2 RU 2360903 C2 RU2360903 C2 RU 2360903C2 RU 2004126448/04 A RU2004126448/04 A RU 2004126448/04A RU 2004126448 A RU2004126448 A RU 2004126448A RU 2360903 C2 RU2360903 C2 RU 2360903C2
- Authority
- RU
- Russia
- Prior art keywords
- formula
- optionally substituted
- aralkyl
- cycloalkyl
- substituted alkyl
- Prior art date
Links
- 0 CO[Tl]1(O*)Oc2ccc(cccc3)c3c2-c(c2ccccc2cc2)c2O1 Chemical compound CO[Tl]1(O*)Oc2ccc(cccc3)c3c2-c(c2ccccc2cc2)c2O1 0.000 description 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Quinoline Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35231602P | 2002-01-28 | 2002-01-28 | |
| US60/352,316 | 2002-01-28 | ||
| US38318802P | 2002-05-24 | 2002-05-24 | |
| US60/383,188 | 2002-05-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2004126448A RU2004126448A (ru) | 2005-06-27 |
| RU2360903C2 true RU2360903C2 (ru) | 2009-07-10 |
Family
ID=27669055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2004126448/04A RU2360903C2 (ru) | 2002-01-28 | 2003-01-27 | Способ получения органических соединений |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US6835838B2 (enExample) |
| EP (1) | EP1472227B1 (enExample) |
| JP (1) | JP2005516064A (enExample) |
| KR (2) | KR20100091267A (enExample) |
| CN (2) | CN1625550A (enExample) |
| AU (4) | AU2003239294B2 (enExample) |
| BR (1) | BR0307236A (enExample) |
| CA (1) | CA2472340A1 (enExample) |
| CO (1) | CO5601045A2 (enExample) |
| EC (1) | ECSP045202A (enExample) |
| IL (1) | IL162817A0 (enExample) |
| MX (1) | MXPA04007308A (enExample) |
| NO (1) | NO327363B1 (enExample) |
| NZ (3) | NZ554366A (enExample) |
| PL (1) | PL371383A1 (enExample) |
| RU (1) | RU2360903C2 (enExample) |
| SG (2) | SG161742A1 (enExample) |
| WO (1) | WO2003064382A2 (enExample) |
| ZA (1) | ZA200405239B (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL159741A0 (en) | 2001-07-13 | 2004-06-20 | Astrazeneca Uk Ltd | Preparation of aminopyrimidine compounds |
| PT1466905E (pt) | 2001-11-14 | 2011-07-14 | Nissan Chemical Ind Ltd | Processo para a produção de éster do ácido oxo-heptenóico opticamente activo |
| DE60326819D1 (de) * | 2002-01-31 | 2009-05-07 | Novartis Ag | Verfahren zur herstellung von inhibitoren der hmg-coa-reduktase |
| EP1539698B1 (en) * | 2002-09-20 | 2010-10-20 | Nissan Chemical Industries, Ltd. | Method for producing a 3,5-dihydroxy-6-heptenoate |
| EP3299359A1 (en) | 2003-02-12 | 2018-03-28 | Nissan Chemical Industries, Ltd. | Crystalline and amorphous forms of pitavastatin hemicalcium salt |
| US7851624B2 (en) * | 2003-12-24 | 2010-12-14 | Teva Pharamaceutical Industries Ltd. | Triol form of rosuvastatin and synthesis of rosuvastatin |
| TWI328006B (en) * | 2003-12-26 | 2010-08-01 | Nissan Chemical Ind Ltd | Crystal form of quinoline compound and process for its production |
| CN1763015B (zh) * | 2004-10-22 | 2011-06-22 | 四川抗菌素工业研究所有限公司 | 一种罗舒伐他汀及其药用盐的制备方法及中间体 |
| GB0428328D0 (en) | 2004-12-24 | 2005-02-02 | Astrazeneca Uk Ltd | Chemical process |
| GB0514078D0 (en) * | 2005-07-08 | 2005-08-17 | Astrazeneca Uk Ltd | Chemical process |
| WO2007125547A2 (en) * | 2006-05-03 | 2007-11-08 | Manne Satyanarayana Reddy | Novel process for statins and its pharmaceutically acceptable salts thereof |
| SI2086945T1 (sl) * | 2006-10-09 | 2016-05-31 | Msn Laboratories Private Limited | Novi postopek za pripravo statinov in njihovih farmacevtsko sprejemljivih soli |
| TW200831469A (en) * | 2006-12-01 | 2008-08-01 | Astrazeneca Uk Ltd | Chemical process |
| WO2010089770A2 (en) * | 2009-01-19 | 2010-08-12 | Msn Laboratories Limited | Improved process for the preparation of highly pure (3r,5s)-7-[2-cyclopropyl-4-(4-fluorophenyl) quinolin-3-yl]-3,5-dihydroxy-6(e)-heptenoic acid and pharmaceutically acceptable salts thereof |
| RU2425034C1 (ru) * | 2010-01-11 | 2011-07-27 | Государственное образовательное учреждение высшего профессионального образования "Кубанский государственный технологический университет" (ГОУ ВПО "КубГТУ") | Способ получения производных (e)-4-(6,7-диметокси-2-метил-3-хинолил)-3-бутен-2-она |
| WO2011086584A2 (en) | 2010-01-18 | 2011-07-21 | Msn Laboratories Limited | Improved process for the preparation of amide intermediates and their use thereof |
| EP2423195A1 (en) | 2010-07-26 | 2012-02-29 | LEK Pharmaceuticals d.d. | Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof |
| US9034901B2 (en) | 2010-08-25 | 2015-05-19 | Cadila Healthcare Limited | Pitavastatin calcium and process for its preparation |
| EP2638013A4 (en) * | 2010-11-12 | 2014-03-26 | Hetero Research Foundation | NEW POLYMORPHS OF CALCIUM PIVASTATIN |
| WO2012140490A2 (en) | 2011-04-11 | 2012-10-18 | Aurobindo Pharma Limited | Process for preparing quinoline derivative |
| CN103755568B (zh) * | 2013-12-10 | 2015-10-28 | 江西科技师范大学 | IeodomycinA和B立体选择性合成方法 |
| JP6704916B2 (ja) | 2015-08-05 | 2020-06-03 | 株式会社エーピーアイ コーポレーション | ピタバスタチンカルシウムの製造方法 |
| CN108976168B (zh) * | 2017-06-02 | 2020-09-25 | 浙江京新药业股份有限公司 | 一种匹伐他汀半钙盐晶型及其制备方法 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0306929A2 (en) * | 1987-09-08 | 1989-03-15 | Warner-Lambert Company | 6-[[(Substituted)pyridin-3-YL]alkyl]-and alkenyl]-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
| EP0356788A2 (en) * | 1988-08-29 | 1990-03-07 | E.R. SQUIBB & SONS, INC. | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors |
| EP0520406A1 (en) * | 1991-06-24 | 1992-12-30 | Nissan Chemical Industries Ltd. | Diastereomer salt of optically active quinolinemevalonic acid |
| EP0521471A1 (en) * | 1991-07-01 | 1993-01-07 | Shionogi Seiyaku Kabushiki Kaisha | Pyrimidine derivatives as HMG-CoA reductase inhibitors |
| RU2114620C1 (ru) * | 1991-10-04 | 1998-07-10 | Ниссан Кемикал Индастриз Лтд. | Ингибитор атеросклеротического утолщения внутренней оболочки сосудов |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3554036B2 (ja) * | 1994-09-06 | 2004-08-11 | 宇部興産株式会社 | 光学活性な７−置換キノリル−３，５−ジヒドロキシ−ヘプト−６−エン酸エステル誘導体の製造方法 |
| PT1466905E (pt) * | 2001-11-14 | 2011-07-14 | Nissan Chemical Ind Ltd | Processo para a produção de éster do ácido oxo-heptenóico opticamente activo |
| EP2125754B1 (en) * | 2007-02-08 | 2012-04-11 | Aurobindo Pharma Limited | Process for preparation of rosuvastatin calcium |
-
2003
- 2003-01-24 US US10/350,615 patent/US6835838B2/en not_active Expired - Lifetime
- 2003-01-27 EP EP03734696.2A patent/EP1472227B1/en not_active Expired - Lifetime
- 2003-01-27 MX MXPA04007308A patent/MXPA04007308A/es active IP Right Grant
- 2003-01-27 JP JP2003564005A patent/JP2005516064A/ja active Pending
- 2003-01-27 CN CNA038028778A patent/CN1625550A/zh active Pending
- 2003-01-27 NZ NZ554366A patent/NZ554366A/en not_active IP Right Cessation
- 2003-01-27 RU RU2004126448/04A patent/RU2360903C2/ru not_active IP Right Cessation
- 2003-01-27 PL PL03371383A patent/PL371383A1/xx unknown
- 2003-01-27 CN CNB200510005170XA patent/CN100378081C/zh not_active Expired - Lifetime
- 2003-01-27 NZ NZ554367A patent/NZ554367A/en not_active IP Right Cessation
- 2003-01-27 AU AU2003239294A patent/AU2003239294B2/en not_active Ceased
- 2003-01-27 KR KR1020107017248A patent/KR20100091267A/ko not_active Ceased
- 2003-01-27 IL IL16281703A patent/IL162817A0/xx unknown
- 2003-01-27 KR KR10-2004-7011572A patent/KR20040077883A/ko not_active Ceased
- 2003-01-27 SG SG200605094-2A patent/SG161742A1/en unknown
- 2003-01-27 BR BR0307236-3A patent/BR0307236A/pt not_active Application Discontinuation
- 2003-01-27 CA CA002472340A patent/CA2472340A1/en not_active Abandoned
- 2003-01-27 NZ NZ534136A patent/NZ534136A/en not_active IP Right Cessation
- 2003-01-27 SG SG200605092-6A patent/SG157225A1/en unknown
- 2003-01-27 WO PCT/EP2003/000804 patent/WO2003064382A2/en not_active Ceased
-
2004
- 2004-07-01 ZA ZA2004/05239A patent/ZA200405239B/en unknown
- 2004-07-14 US US10/891,357 patent/US7572917B2/en not_active Expired - Fee Related
- 2004-07-22 EC EC2004005202A patent/ECSP045202A/es unknown
- 2004-08-06 CO CO04076720A patent/CO5601045A2/es not_active Application Discontinuation
- 2004-08-27 NO NO20043586A patent/NO327363B1/no not_active IP Right Cessation
-
2006
- 2006-10-03 AU AU2006225206A patent/AU2006225206B2/en not_active Ceased
- 2006-10-03 AU AU2006225205A patent/AU2006225205B2/en not_active Ceased
-
2009
- 2009-07-02 US US12/497,001 patent/US20090299065A1/en not_active Abandoned
- 2009-08-12 AU AU2009208129A patent/AU2009208129A1/en not_active Abandoned
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0306929A2 (en) * | 1987-09-08 | 1989-03-15 | Warner-Lambert Company | 6-[[(Substituted)pyridin-3-YL]alkyl]-and alkenyl]-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
| EP0356788A2 (en) * | 1988-08-29 | 1990-03-07 | E.R. SQUIBB & SONS, INC. | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors |
| EP0520406A1 (en) * | 1991-06-24 | 1992-12-30 | Nissan Chemical Industries Ltd. | Diastereomer salt of optically active quinolinemevalonic acid |
| EP0521471A1 (en) * | 1991-07-01 | 1993-01-07 | Shionogi Seiyaku Kabushiki Kaisha | Pyrimidine derivatives as HMG-CoA reductase inhibitors |
| US5260440A (en) * | 1991-07-01 | 1993-11-09 | Shionogi Seiyaku Kabushiki Kaisha | Pyrimidine derivatives |
| RU2114620C1 (ru) * | 1991-10-04 | 1998-07-10 | Ниссан Кемикал Индастриз Лтд. | Ингибитор атеросклеротического утолщения внутренней оболочки сосудов |
Non-Patent Citations (1)
| Title |
|---|
| SORIENTE A. et al. TETRAHEDRON: ASYMMETRY, vol.12, 2001-04, p.959-963. MIKIO SUZUKI et al. BIOORGANIC & MEDICINAL CHEMISTRY, vol.9, no.10, 2001-10, p.2727-2743. * |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20180128 |