SG148860A1 - Stereospecific reduction of sapogen-3-ones - Google Patents

Stereospecific reduction of sapogen-3-ones

Info

Publication number
SG148860A1
SG148860A1 SG200703083-6A SG2007030836A SG148860A1 SG 148860 A1 SG148860 A1 SG 148860A1 SG 2007030836 A SG2007030836 A SG 2007030836A SG 148860 A1 SG148860 A1 SG 148860A1
Authority
SG
Singapore
Prior art keywords
sapogen
ones
stereospecific reduction
stereospecific
reduction
Prior art date
Application number
SG200703083-6A
Other languages
English (en)
Inventor
Philip James Gunning
Peter David Tiffin
Original Assignee
Phytopharm Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0225106A external-priority patent/GB0225106D0/en
Priority claimed from GB0301505A external-priority patent/GB0301505D0/en
Application filed by Phytopharm Plc filed Critical Phytopharm Plc
Publication of SG148860A1 publication Critical patent/SG148860A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
SG200703083-6A 2002-10-28 2003-04-28 Stereospecific reduction of sapogen-3-ones SG148860A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0225106A GB0225106D0 (en) 2002-10-28 2002-10-28 Synthesis of 3 hydroxy-5 -steroids
GB0301505A GB0301505D0 (en) 2003-01-22 2003-01-22 Stereospecific synthesis of sapogenins

Publications (1)

Publication Number Publication Date
SG148860A1 true SG148860A1 (en) 2009-01-29

Family

ID=32178884

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200703083-6A SG148860A1 (en) 2002-10-28 2003-04-28 Stereospecific reduction of sapogen-3-ones

Country Status (17)

Country Link
US (1) US7718792B2 (ko)
EP (1) EP1558627B1 (ko)
JP (1) JP4607758B2 (ko)
KR (1) KR101092150B1 (ko)
AT (1) ATE459636T1 (ko)
AU (1) AU2003224308A1 (ko)
BR (1) BR0315746A (ko)
CA (1) CA2503899C (ko)
DE (1) DE60331572D1 (ko)
ES (1) ES2342274T3 (ko)
MX (1) MXPA05004494A (ko)
PL (1) PL210114B1 (ko)
PT (1) PT1558627E (ko)
RU (1) RU2326890C2 (ko)
SG (1) SG148860A1 (ko)
TW (1) TWI334781B (ko)
WO (1) WO2004037845A1 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0000228D0 (en) * 2000-01-06 2000-03-01 Phytopharm Plc Fluoro substituted sapogenins and their use
CN102727501A (zh) * 2002-03-27 2012-10-17 菲特法姆股份有限公司 皂角苷配基及其衍生物的用途
GB0409567D0 (en) * 2004-04-28 2004-06-02 Phytopharm Plc Chemical compounds
JP2011518846A (ja) * 2008-04-30 2011-06-30 インスティテュート オブ ラジエーション メディシン，アカデミー オブ ミリタリー メディカル サイエンシズ，ピーエルエー チモサポニンｂｉｉの合成
CN106810592A (zh) * 2016-11-29 2017-06-09 杭州裕美生物科技有限公司 一种4‑烯‑3,6‑二酮甾体的合成工艺

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150336A (en) * 1995-05-29 2000-11-21 Pfizer Inc. Steroidal glycosides

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB736818A (en) 1951-12-28 1955-09-14 Glidden Co Improvements in or relating to preparation of 3-keto steroids having cis junction of rings a and b
GB763301A (en) 1953-09-05 1956-12-12 Farmaceutici Italia Process for the reduction of í¸-3-keto-steroids to 5-ª -dihydro-steroids
DE2257132C3 (de) 1972-11-18 1982-05-13 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Reduktion von 3-Ketosteroiden
CA2139104A1 (en) * 1992-06-26 1994-01-06 Michael P. Deninno Steroidal glycosides for treating hypercholesterolemia
WO1995018143A1 (en) 1993-12-28 1995-07-06 Pfizer Inc. Hypocholesterolemic agents
AU2453295A (en) * 1994-09-20 1996-04-19 Pfizer Inc. Combination of a cholesterol absorption inhibitor and a cholesterol synthesis inhibitor
EP1066033B1 (en) 1998-03-26 2005-12-28 Phytopharm Plc Smilagenin and anzurogenin-d for the treatment of alzheimer's disease
GB9923076D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
GB0000228D0 (en) * 2000-01-06 2000-03-01 Phytopharm Plc Fluoro substituted sapogenins and their use
GB0107822D0 (en) * 2001-03-28 2001-05-23 Phytopharm Plc Sapogenin derivatives their synthesis and use methods based upon their use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150336A (en) * 1995-05-29 2000-11-21 Pfizer Inc. Steroidal glycosides

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EPI- SARSASAPOGENIN AND EPI-SMILAGENIN: TWO SAPOGENINS ISOLATED FROM THE RUMEN CONTENT OF SHEEP INTOXICATED BY BRACHIARIA DECUMBENS *
STEROLS. LVI. SARSASAPOGENIN DERIVATIVES. EPI- SARSASAPOGENIN *

Also Published As

Publication number Publication date
PL210114B1 (pl) 2011-12-30
EP1558627A1 (en) 2005-08-03
JP4607758B2 (ja) 2011-01-05
TW200406215A (en) 2004-05-01
TWI334781B (en) 2010-12-21
DE60331572D1 (de) 2010-04-15
US7718792B2 (en) 2010-05-18
ES2342274T3 (es) 2010-07-05
WO2004037845A1 (en) 2004-05-06
PT1558627E (pt) 2010-05-06
MXPA05004494A (es) 2005-07-26
EP1558627B1 (en) 2010-03-03
BR0315746A (pt) 2005-09-06
ATE459636T1 (de) 2010-03-15
CA2503899C (en) 2011-12-20
AU2003224308A1 (en) 2004-05-13
KR20050090379A (ko) 2005-09-13
CA2503899A1 (en) 2004-05-06
PL376791A1 (pl) 2006-01-09
US20060041119A1 (en) 2006-02-23
KR101092150B1 (ko) 2011-12-12
RU2326890C2 (ru) 2008-06-20
RU2005111593A (ru) 2006-05-10
JP2006507360A (ja) 2006-03-02

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