SG144722A1 - Method and apparatus for detecting and imaging the presence of biological materials - Google Patents
Method and apparatus for detecting and imaging the presence of biological materialsInfo
- Publication number
- SG144722A1 SG144722A1 SG200402988-0A SG2004029880A SG144722A1 SG 144722 A1 SG144722 A1 SG 144722A1 SG 2004029880 A SG2004029880 A SG 2004029880A SG 144722 A1 SG144722 A1 SG 144722A1
- Authority
- SG
- Singapore
- Prior art keywords
- imaging
- detecting
- fluorophores
- biological materials
- excitation light
- Prior art date
Links
- 239000012620 biological material Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 238000003384 imaging method Methods 0.000 title abstract 2
- 230000005284 excitation Effects 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 1
- 230000005670 electromagnetic radiation Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
- G01N21/274—Calibration, base line adjustment, drift correction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/55—Specular reflectivity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N2021/1734—Sequential different kinds of measurements; Combining two or more methods
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/33—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mathematical Physics (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biomedical Technology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/817,647 US7186990B2 (en) | 2002-01-22 | 2004-04-02 | Method and apparatus for detecting and imaging the presence of biological materials |
Publications (1)
Publication Number | Publication Date |
---|---|
SG144722A1 true SG144722A1 (en) | 2008-08-28 |
Family
ID=34887789
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG200402988-0A SG144722A1 (en) | 2004-04-02 | 2004-05-27 | Method and apparatus for detecting and imaging the presence of biological materials |
Country Status (6)
Country | Link |
---|---|
US (1) | US7186990B2 (fr) |
EP (1) | EP1582860A1 (fr) |
JP (1) | JP2005292112A (fr) |
CN (1) | CN100561200C (fr) |
CA (1) | CA2466433A1 (fr) |
SG (1) | SG144722A1 (fr) |
Families Citing this family (59)
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US5914613A (en) | 1996-08-08 | 1999-06-22 | Cascade Microtech, Inc. | Membrane probing system with local contact scrub |
US6256882B1 (en) | 1998-07-14 | 2001-07-10 | Cascade Microtech, Inc. | Membrane probing system |
US6914423B2 (en) | 2000-09-05 | 2005-07-05 | Cascade Microtech, Inc. | Probe station |
US6965226B2 (en) | 2000-09-05 | 2005-11-15 | Cascade Microtech, Inc. | Chuck for holding a device under test |
DE20114544U1 (de) | 2000-12-04 | 2002-02-21 | Cascade Microtech, Inc., Beaverton, Oreg. | Wafersonde |
US7355420B2 (en) | 2001-08-21 | 2008-04-08 | Cascade Microtech, Inc. | Membrane probing system |
US7492172B2 (en) | 2003-05-23 | 2009-02-17 | Cascade Microtech, Inc. | Chuck for holding a device under test |
US7057404B2 (en) | 2003-05-23 | 2006-06-06 | Sharp Laboratories Of America, Inc. | Shielded probe for testing a device under test |
US7250626B2 (en) | 2003-10-22 | 2007-07-31 | Cascade Microtech, Inc. | Probe testing structure |
WO2005065258A2 (fr) | 2003-12-24 | 2005-07-21 | Cascade Microtech, Inc. | Sonde de tranche a semi-conducteur possedant un circuit actif |
US7187188B2 (en) | 2003-12-24 | 2007-03-06 | Cascade Microtech, Inc. | Chuck with integrated wafer support |
WO2006022823A1 (fr) | 2004-07-29 | 2006-03-02 | Centrus International, Inc. | Détection de micro-organismes à l’aide d’un dispositif à fluorescence |
US7420381B2 (en) | 2004-09-13 | 2008-09-02 | Cascade Microtech, Inc. | Double sided probing structures |
US7545969B2 (en) * | 2004-12-16 | 2009-06-09 | Alliant Techsystems Inc. | Method and system for wide-area ultraviolet detection of forensic evidence |
US7535247B2 (en) | 2005-01-31 | 2009-05-19 | Cascade Microtech, Inc. | Interface for testing semiconductors |
US7656172B2 (en) | 2005-01-31 | 2010-02-02 | Cascade Microtech, Inc. | System for testing semiconductors |
JP2006263044A (ja) * | 2005-03-23 | 2006-10-05 | Fuji Photo Film Co Ltd | 蛍光検出システム |
JP5289675B2 (ja) * | 2005-12-14 | 2013-09-11 | 京セラディスプレイ株式会社 | 汚染物質の除去方法 |
US7764072B2 (en) | 2006-06-12 | 2010-07-27 | Cascade Microtech, Inc. | Differential signal probing system |
US7723999B2 (en) | 2006-06-12 | 2010-05-25 | Cascade Microtech, Inc. | Calibration structures for differential signal probing |
US7403028B2 (en) | 2006-06-12 | 2008-07-22 | Cascade Microtech, Inc. | Test structure and probe for differential signals |
DE102006000318A1 (de) | 2006-07-03 | 2008-01-10 | Novineon Healthcare Technology Partners Gmbh | Vorrichtung zur Blutungsdetektion |
US20080012578A1 (en) * | 2006-07-14 | 2008-01-17 | Cascade Microtech, Inc. | System for detecting molecular structure and events |
US7876114B2 (en) | 2007-08-08 | 2011-01-25 | Cascade Microtech, Inc. | Differential waveguide probe |
US7615761B2 (en) * | 2007-09-10 | 2009-11-10 | Coherent, Inc. | Trace evidence detection using multiple laser light sources |
EP2197350A2 (fr) * | 2007-09-11 | 2010-06-23 | Baxter International Inc. | Système de capteur pour thérapie par perfusion |
US8512975B2 (en) | 2008-07-24 | 2013-08-20 | Biomerieux, Inc. | Method for detection and characterization of a microorganism in a sample using time dependent spectroscopic measurements |
US7888957B2 (en) | 2008-10-06 | 2011-02-15 | Cascade Microtech, Inc. | Probing apparatus with impedance optimized interface |
WO2010062356A1 (fr) * | 2008-10-31 | 2010-06-03 | Biomerieux, Inc. | Procédés pour la séparation, la caractérisation et/ou l'identification de microorganismes à l'aide de la spectroscopie |
KR20110091719A (ko) * | 2008-10-31 | 2011-08-12 | 바이오메리욱스, 인코포레이티드. | 식별제를 사용한 미생물의 분리 및 특성규명 방법 |
BRPI0919861A2 (pt) * | 2008-10-31 | 2017-04-04 | Bio Merieux Inc | metodos para a separacao, caracterizacao e/ou identificacao de micro-organismos por espectroscopia raman |
CN102317789B (zh) | 2008-10-31 | 2014-08-27 | 生物梅里埃公司 | 利用质谱法分离、表征和/或鉴定微生物的方法 |
US8647835B2 (en) | 2008-10-31 | 2014-02-11 | BIO MéRIEUX, INC. | Methods for separation, characterization and/or identification of microorganisms using spectroscopy |
EP2364356B1 (fr) * | 2008-10-31 | 2019-06-19 | Biomerieux, Inc | Procédés pour détection et identification de micro-organismes |
EP2364447B1 (fr) * | 2008-10-31 | 2019-06-12 | Biomerieux, Inc | Procédé pour l' identification de micro-organismes |
US8410806B2 (en) | 2008-11-21 | 2013-04-02 | Cascade Microtech, Inc. | Replaceable coupon for a probing apparatus |
US8319503B2 (en) | 2008-11-24 | 2012-11-27 | Cascade Microtech, Inc. | Test apparatus for measuring a characteristic of a device under test |
BRPI0922952B8 (pt) * | 2008-12-16 | 2021-07-27 | Bio Merieux Inc | métodos de detectar e identificar um microorganismos em meios sólidos ou semi-sólidos |
RU2559909C2 (ru) | 2009-05-15 | 2015-08-20 | Биомерьё, Инк. | Автоматизированное устройство для обнаружения микробов |
JP2012526996A (ja) | 2009-05-15 | 2012-11-01 | ビオメリュー・インコーポレイテッド | 試料内の微生物因子の迅速な同定および/または特徴付けのためのシステムおよび方法 |
BR112012031252B1 (pt) * | 2010-06-11 | 2020-06-30 | B. Braun Avitum Ag | aparelho para tratamento extracorpóreo de sangue |
US20130230866A1 (en) * | 2010-09-17 | 2013-09-05 | Tohoku University | Method for Determining Effectiveness of Medicine Containing Antibody as Component |
JP2014501910A (ja) * | 2010-10-27 | 2014-01-23 | コーニンクレッカ フィリップス エヌ ヴェ | 存在検出システム及び証明システム |
US20120119110A1 (en) * | 2010-11-16 | 2012-05-17 | Research In Motion Limited | Apparatus, and associated method, for detecting contamination of an object |
EP2520923A1 (fr) | 2011-05-06 | 2012-11-07 | bioMérieux | Bio-imaging method and system |
JP6257523B2 (ja) | 2011-12-22 | 2018-01-10 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 感染性微生物の迅速な検出のための方法及び装置 |
EP2893029B1 (fr) | 2012-09-04 | 2017-09-27 | Becton, Dickinson and Company | Pré-concentration bactérienne et technique de détection |
US20140125809A1 (en) | 2012-11-02 | 2014-05-08 | Syntronics, Llc | Digital ruvis camera |
WO2015089514A2 (fr) * | 2013-12-13 | 2015-06-18 | Colorado State University Research Foundation | Nano-estampille et lecteur associé à des fins d'applications anti-contrefaçon |
US10039934B2 (en) * | 2013-12-30 | 2018-08-07 | PhotonEdge Inc. | Multi-wavelength interleaved optical stimulation |
WO2016022894A1 (fr) * | 2014-08-07 | 2016-02-11 | Teleflex Medical Incorporated | Sonde à fibre optique de détection d'urine, et système pour néphrostomie percutanée |
US9880159B2 (en) | 2014-10-01 | 2018-01-30 | Linda S. Powers | Cartridge-based detection system |
US9867250B1 (en) | 2015-04-20 | 2018-01-09 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | System having a configurable pico-second pulsed LED driver circuit and photomultiplier tube biasing and gating circuits for real-time, time-resolved transient recording of fluorescence |
EP3559721B1 (fr) * | 2016-12-23 | 2021-09-15 | Bio-Rad Laboratories, Inc. | Réduction d'un signal d'arrière-plan dans des images de transfert |
JP7014794B2 (ja) * | 2017-07-11 | 2022-02-01 | 浜松ホトニクス株式会社 | 試料観察装置及び試料観察方法 |
JP7007122B2 (ja) * | 2017-07-11 | 2022-01-24 | 浜松ホトニクス株式会社 | 試料観察装置及び試料観察方法 |
CN110197174A (zh) * | 2018-02-26 | 2019-09-03 | 刘风华 | 文物、字画和原产商品的数字化技术 |
US11269203B2 (en) | 2020-01-23 | 2022-03-08 | Hong Kong Applied Science And Technology Institute Company Limited | Multifocal system with polarization-independent focusing |
US11408825B2 (en) | 2020-08-28 | 2022-08-09 | Hong Kong Applied Science and Technology Research Institute Company Limited | Forensic detector and the system thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5968766A (en) * | 1998-03-31 | 1999-10-19 | B.E. Safe | Method and apparatus for sensing the presence of microbes |
US20030138875A1 (en) * | 2002-01-22 | 2003-07-24 | Powers Linda S. | Method and apparatus for detecting the presence of microbes and determining their physiological status |
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US3580525A (en) * | 1967-11-21 | 1971-05-25 | Telefunken Patent | Arrangement maintaining constant tape tension in magnetic tape recorders |
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US4745285A (en) | 1986-08-21 | 1988-05-17 | Becton Dickinson And Company | Multi-color fluorescence analysis with single wavelength excitation |
US4900934A (en) | 1987-07-15 | 1990-02-13 | University Of Utah | Apparatus for simultaneous visualization and measurement of fluorescence from fluorescent dye-treated cell preparations and solutions |
US5208651A (en) | 1991-07-16 | 1993-05-04 | The Regents Of The University Of California | Apparatus and method for measuring fluorescence intensities at a plurality of wavelengths and lifetimes |
US5294799A (en) | 1993-02-01 | 1994-03-15 | Aslund Nils R D | Apparatus for quantitative imaging of multiple fluorophores |
US5418371A (en) | 1993-02-01 | 1995-05-23 | Aslund; Nils R. D. | Apparatus for quantitative imaging of multiple fluorophores using dual detectors |
US5424959A (en) | 1993-07-19 | 1995-06-13 | Texaco Inc. | Interpretation of fluorescence fingerprints of crude oils and other hydrocarbon mixtures using neural networks |
US5474910A (en) | 1993-10-15 | 1995-12-12 | Alfano; Robert R. | Method and device for detecting biological molecules and/or microorganisms within a desired area or space |
US5491343A (en) | 1994-03-25 | 1996-02-13 | Brooker; Gary | High-speed multiple wavelength illumination source, apparatus containing the same, and applications thereof to methods of irradiating luminescent samples and of quantitative luminescence ratio microscopy |
US5701012A (en) | 1996-03-19 | 1997-12-23 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence | Fluorescent biological particle detection system |
US5760406A (en) | 1996-06-03 | 1998-06-02 | Powers; Linda | Method and apparatus for sensing the presence of microbes |
US5866430A (en) | 1996-06-13 | 1999-02-02 | Grow; Ann E. | Raman optrode processes and devices for detection of chemicals and microorganisms |
US6139800A (en) | 1997-06-23 | 2000-10-31 | Luminex Corporation | Interlaced lasers for multiple fluorescence measurement |
US6124597A (en) | 1997-07-07 | 2000-09-26 | Cedars-Sinai Medical Center | Method and devices for laser induced fluorescence attenuation spectroscopy |
-
2004
- 2004-04-02 US US10/817,647 patent/US7186990B2/en not_active Expired - Fee Related
- 2004-05-05 CA CA002466433A patent/CA2466433A1/fr not_active Abandoned
- 2004-05-20 JP JP2004151028A patent/JP2005292112A/ja active Pending
- 2004-05-26 EP EP04012456A patent/EP1582860A1/fr not_active Withdrawn
- 2004-05-27 SG SG200402988-0A patent/SG144722A1/en unknown
- 2004-06-10 CN CNB2004100492958A patent/CN100561200C/zh not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5968766A (en) * | 1998-03-31 | 1999-10-19 | B.E. Safe | Method and apparatus for sensing the presence of microbes |
US20030138875A1 (en) * | 2002-01-22 | 2003-07-24 | Powers Linda S. | Method and apparatus for detecting the presence of microbes and determining their physiological status |
Also Published As
Publication number | Publication date |
---|---|
US7186990B2 (en) | 2007-03-06 |
CN1677088A (zh) | 2005-10-05 |
CA2466433A1 (fr) | 2005-10-02 |
EP1582860A1 (fr) | 2005-10-05 |
JP2005292112A (ja) | 2005-10-20 |
US20040197771A1 (en) | 2004-10-07 |
CN100561200C (zh) | 2009-11-18 |
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