SG144722A1 - Method and apparatus for detecting and imaging the presence of biological materials - Google Patents

Method and apparatus for detecting and imaging the presence of biological materials

Info

Publication number
SG144722A1
SG144722A1 SG200402988-0A SG2004029880A SG144722A1 SG 144722 A1 SG144722 A1 SG 144722A1 SG 2004029880 A SG2004029880 A SG 2004029880A SG 144722 A1 SG144722 A1 SG 144722A1
Authority
SG
Singapore
Prior art keywords
imaging
detecting
fluorophores
biological materials
excitation light
Prior art date
Application number
SG200402988-0A
Other languages
English (en)
Inventor
Linda S Powers
Christopher R Lloyd
Original Assignee
Microbiosystems Ltd Partnershi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbiosystems Ltd Partnershi filed Critical Microbiosystems Ltd Partnershi
Publication of SG144722A1 publication Critical patent/SG144722A1/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6486Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274Calibration, base line adjustment, drift correction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/1734Sequential different kinds of measurements; Combining two or more methods
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N2021/6417Spectrofluorimetric devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/33Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mathematical Physics (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biomedical Technology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SG200402988-0A 2004-04-02 2004-05-27 Method and apparatus for detecting and imaging the presence of biological materials SG144722A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/817,647 US7186990B2 (en) 2002-01-22 2004-04-02 Method and apparatus for detecting and imaging the presence of biological materials

Publications (1)

Publication Number Publication Date
SG144722A1 true SG144722A1 (en) 2008-08-28

Family

ID=34887789

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200402988-0A SG144722A1 (en) 2004-04-02 2004-05-27 Method and apparatus for detecting and imaging the presence of biological materials

Country Status (6)

Country Link
US (1) US7186990B2 (fr)
EP (1) EP1582860A1 (fr)
JP (1) JP2005292112A (fr)
CN (1) CN100561200C (fr)
CA (1) CA2466433A1 (fr)
SG (1) SG144722A1 (fr)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5914613A (en) 1996-08-08 1999-06-22 Cascade Microtech, Inc. Membrane probing system with local contact scrub
US6256882B1 (en) 1998-07-14 2001-07-10 Cascade Microtech, Inc. Membrane probing system
US6914423B2 (en) 2000-09-05 2005-07-05 Cascade Microtech, Inc. Probe station
US6965226B2 (en) 2000-09-05 2005-11-15 Cascade Microtech, Inc. Chuck for holding a device under test
DE20114544U1 (de) 2000-12-04 2002-02-21 Cascade Microtech, Inc., Beaverton, Oreg. Wafersonde
US7355420B2 (en) 2001-08-21 2008-04-08 Cascade Microtech, Inc. Membrane probing system
US7492172B2 (en) 2003-05-23 2009-02-17 Cascade Microtech, Inc. Chuck for holding a device under test
US7057404B2 (en) 2003-05-23 2006-06-06 Sharp Laboratories Of America, Inc. Shielded probe for testing a device under test
US7250626B2 (en) 2003-10-22 2007-07-31 Cascade Microtech, Inc. Probe testing structure
WO2005065258A2 (fr) 2003-12-24 2005-07-21 Cascade Microtech, Inc. Sonde de tranche a semi-conducteur possedant un circuit actif
US7187188B2 (en) 2003-12-24 2007-03-06 Cascade Microtech, Inc. Chuck with integrated wafer support
WO2006022823A1 (fr) 2004-07-29 2006-03-02 Centrus International, Inc. Détection de micro-organismes à l’aide d’un dispositif à fluorescence
US7420381B2 (en) 2004-09-13 2008-09-02 Cascade Microtech, Inc. Double sided probing structures
US7545969B2 (en) * 2004-12-16 2009-06-09 Alliant Techsystems Inc. Method and system for wide-area ultraviolet detection of forensic evidence
US7535247B2 (en) 2005-01-31 2009-05-19 Cascade Microtech, Inc. Interface for testing semiconductors
US7656172B2 (en) 2005-01-31 2010-02-02 Cascade Microtech, Inc. System for testing semiconductors
JP2006263044A (ja) * 2005-03-23 2006-10-05 Fuji Photo Film Co Ltd 蛍光検出システム
JP5289675B2 (ja) * 2005-12-14 2013-09-11 京セラディスプレイ株式会社 汚染物質の除去方法
US7764072B2 (en) 2006-06-12 2010-07-27 Cascade Microtech, Inc. Differential signal probing system
US7723999B2 (en) 2006-06-12 2010-05-25 Cascade Microtech, Inc. Calibration structures for differential signal probing
US7403028B2 (en) 2006-06-12 2008-07-22 Cascade Microtech, Inc. Test structure and probe for differential signals
DE102006000318A1 (de) 2006-07-03 2008-01-10 Novineon Healthcare Technology Partners Gmbh Vorrichtung zur Blutungsdetektion
US20080012578A1 (en) * 2006-07-14 2008-01-17 Cascade Microtech, Inc. System for detecting molecular structure and events
US7876114B2 (en) 2007-08-08 2011-01-25 Cascade Microtech, Inc. Differential waveguide probe
US7615761B2 (en) * 2007-09-10 2009-11-10 Coherent, Inc. Trace evidence detection using multiple laser light sources
EP2197350A2 (fr) * 2007-09-11 2010-06-23 Baxter International Inc. Système de capteur pour thérapie par perfusion
US8512975B2 (en) 2008-07-24 2013-08-20 Biomerieux, Inc. Method for detection and characterization of a microorganism in a sample using time dependent spectroscopic measurements
US7888957B2 (en) 2008-10-06 2011-02-15 Cascade Microtech, Inc. Probing apparatus with impedance optimized interface
WO2010062356A1 (fr) * 2008-10-31 2010-06-03 Biomerieux, Inc. Procédés pour la séparation, la caractérisation et/ou l'identification de microorganismes à l'aide de la spectroscopie
KR20110091719A (ko) * 2008-10-31 2011-08-12 바이오메리욱스, 인코포레이티드. 식별제를 사용한 미생물의 분리 및 특성규명 방법
BRPI0919861A2 (pt) * 2008-10-31 2017-04-04 Bio Merieux Inc metodos para a separacao, caracterizacao e/ou identificacao de micro-organismos por espectroscopia raman
CN102317789B (zh) 2008-10-31 2014-08-27 生物梅里埃公司 利用质谱法分离、表征和/或鉴定微生物的方法
US8647835B2 (en) 2008-10-31 2014-02-11 BIO MéRIEUX, INC. Methods for separation, characterization and/or identification of microorganisms using spectroscopy
EP2364356B1 (fr) * 2008-10-31 2019-06-19 Biomerieux, Inc Procédés pour détection et identification de micro-organismes
EP2364447B1 (fr) * 2008-10-31 2019-06-12 Biomerieux, Inc Procédé pour l' identification de micro-organismes
US8410806B2 (en) 2008-11-21 2013-04-02 Cascade Microtech, Inc. Replaceable coupon for a probing apparatus
US8319503B2 (en) 2008-11-24 2012-11-27 Cascade Microtech, Inc. Test apparatus for measuring a characteristic of a device under test
BRPI0922952B8 (pt) * 2008-12-16 2021-07-27 Bio Merieux Inc métodos de detectar e identificar um microorganismos em meios sólidos ou semi-sólidos
RU2559909C2 (ru) 2009-05-15 2015-08-20 Биомерьё, Инк. Автоматизированное устройство для обнаружения микробов
JP2012526996A (ja) 2009-05-15 2012-11-01 ビオメリュー・インコーポレイテッド 試料内の微生物因子の迅速な同定および/または特徴付けのためのシステムおよび方法
BR112012031252B1 (pt) * 2010-06-11 2020-06-30 B. Braun Avitum Ag aparelho para tratamento extracorpóreo de sangue
US20130230866A1 (en) * 2010-09-17 2013-09-05 Tohoku University Method for Determining Effectiveness of Medicine Containing Antibody as Component
JP2014501910A (ja) * 2010-10-27 2014-01-23 コーニンクレッカ フィリップス エヌ ヴェ 存在検出システム及び証明システム
US20120119110A1 (en) * 2010-11-16 2012-05-17 Research In Motion Limited Apparatus, and associated method, for detecting contamination of an object
EP2520923A1 (fr) 2011-05-06 2012-11-07 bioMérieux Bio-imaging method and system
JP6257523B2 (ja) 2011-12-22 2018-01-10 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company 感染性微生物の迅速な検出のための方法及び装置
EP2893029B1 (fr) 2012-09-04 2017-09-27 Becton, Dickinson and Company Pré-concentration bactérienne et technique de détection
US20140125809A1 (en) 2012-11-02 2014-05-08 Syntronics, Llc Digital ruvis camera
WO2015089514A2 (fr) * 2013-12-13 2015-06-18 Colorado State University Research Foundation Nano-estampille et lecteur associé à des fins d'applications anti-contrefaçon
US10039934B2 (en) * 2013-12-30 2018-08-07 PhotonEdge Inc. Multi-wavelength interleaved optical stimulation
WO2016022894A1 (fr) * 2014-08-07 2016-02-11 Teleflex Medical Incorporated Sonde à fibre optique de détection d'urine, et système pour néphrostomie percutanée
US9880159B2 (en) 2014-10-01 2018-01-30 Linda S. Powers Cartridge-based detection system
US9867250B1 (en) 2015-04-20 2018-01-09 The Arizona Board Of Regents On Behalf Of The University Of Arizona System having a configurable pico-second pulsed LED driver circuit and photomultiplier tube biasing and gating circuits for real-time, time-resolved transient recording of fluorescence
EP3559721B1 (fr) * 2016-12-23 2021-09-15 Bio-Rad Laboratories, Inc. Réduction d'un signal d'arrière-plan dans des images de transfert
JP7014794B2 (ja) * 2017-07-11 2022-02-01 浜松ホトニクス株式会社 試料観察装置及び試料観察方法
JP7007122B2 (ja) * 2017-07-11 2022-01-24 浜松ホトニクス株式会社 試料観察装置及び試料観察方法
CN110197174A (zh) * 2018-02-26 2019-09-03 刘风华 文物、字画和原产商品的数字化技术
US11269203B2 (en) 2020-01-23 2022-03-08 Hong Kong Applied Science And Technology Institute Company Limited Multifocal system with polarization-independent focusing
US11408825B2 (en) 2020-08-28 2022-08-09 Hong Kong Applied Science and Technology Research Institute Company Limited Forensic detector and the system thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968766A (en) * 1998-03-31 1999-10-19 B.E. Safe Method and apparatus for sensing the presence of microbes
US20030138875A1 (en) * 2002-01-22 2003-07-24 Powers Linda S. Method and apparatus for detecting the presence of microbes and determining their physiological status

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3580525A (en) * 1967-11-21 1971-05-25 Telefunken Patent Arrangement maintaining constant tape tension in magnetic tape recorders
US3850525A (en) 1973-07-09 1974-11-26 Beckman Instruments Inc Simultaneous multiple measurements in laser photometers
US4745285A (en) 1986-08-21 1988-05-17 Becton Dickinson And Company Multi-color fluorescence analysis with single wavelength excitation
US4900934A (en) 1987-07-15 1990-02-13 University Of Utah Apparatus for simultaneous visualization and measurement of fluorescence from fluorescent dye-treated cell preparations and solutions
US5208651A (en) 1991-07-16 1993-05-04 The Regents Of The University Of California Apparatus and method for measuring fluorescence intensities at a plurality of wavelengths and lifetimes
US5294799A (en) 1993-02-01 1994-03-15 Aslund Nils R D Apparatus for quantitative imaging of multiple fluorophores
US5418371A (en) 1993-02-01 1995-05-23 Aslund; Nils R. D. Apparatus for quantitative imaging of multiple fluorophores using dual detectors
US5424959A (en) 1993-07-19 1995-06-13 Texaco Inc. Interpretation of fluorescence fingerprints of crude oils and other hydrocarbon mixtures using neural networks
US5474910A (en) 1993-10-15 1995-12-12 Alfano; Robert R. Method and device for detecting biological molecules and/or microorganisms within a desired area or space
US5491343A (en) 1994-03-25 1996-02-13 Brooker; Gary High-speed multiple wavelength illumination source, apparatus containing the same, and applications thereof to methods of irradiating luminescent samples and of quantitative luminescence ratio microscopy
US5701012A (en) 1996-03-19 1997-12-23 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Fluorescent biological particle detection system
US5760406A (en) 1996-06-03 1998-06-02 Powers; Linda Method and apparatus for sensing the presence of microbes
US5866430A (en) 1996-06-13 1999-02-02 Grow; Ann E. Raman optrode processes and devices for detection of chemicals and microorganisms
US6139800A (en) 1997-06-23 2000-10-31 Luminex Corporation Interlaced lasers for multiple fluorescence measurement
US6124597A (en) 1997-07-07 2000-09-26 Cedars-Sinai Medical Center Method and devices for laser induced fluorescence attenuation spectroscopy

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968766A (en) * 1998-03-31 1999-10-19 B.E. Safe Method and apparatus for sensing the presence of microbes
US20030138875A1 (en) * 2002-01-22 2003-07-24 Powers Linda S. Method and apparatus for detecting the presence of microbes and determining their physiological status

Also Published As

Publication number Publication date
US7186990B2 (en) 2007-03-06
CN1677088A (zh) 2005-10-05
CA2466433A1 (fr) 2005-10-02
EP1582860A1 (fr) 2005-10-05
JP2005292112A (ja) 2005-10-20
US20040197771A1 (en) 2004-10-07
CN100561200C (zh) 2009-11-18

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