SG140147A1 - Combination of a hypnotic agent and substituted bis aryl and heteroaryl compound and therapeutic application thereof - Google Patents

Combination of a hypnotic agent and substituted bis aryl and heteroaryl compound and therapeutic application thereof

Info

Publication number
SG140147A1
SG140147A1 SG200801326A SG200801326A SG140147A1 SG 140147 A1 SG140147 A1 SG 140147A1 SG 200801326 A SG200801326 A SG 200801326A SG 200801326 A SG200801326 A SG 200801326A SG 140147 A1 SG140147 A1 SG 140147A1
Authority
SG
Singapore
Prior art keywords
combination
therapeutic application
heteroaryl compound
substituted bis
hypnotic agent
Prior art date
Application number
SG200801326A
Other languages
English (en)
Inventor
Gary T Emmons
Sathapana Kongsamut
Craig N Karson
Corrine M Legoff
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of SG140147A1 publication Critical patent/SG140147A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
SG200801326A 2005-08-19 2006-08-16 Combination of a hypnotic agent and substituted bis aryl and heteroaryl compound and therapeutic application thereof SG140147A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US70965505P 2005-08-19 2005-08-19

Publications (1)

Publication Number Publication Date
SG140147A1 true SG140147A1 (en) 2008-03-28

Family

ID=37772166

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200801326A SG140147A1 (en) 2005-08-19 2006-08-16 Combination of a hypnotic agent and substituted bis aryl and heteroaryl compound and therapeutic application thereof

Country Status (17)

Country Link
US (1) US7618650B2 (es)
EP (1) EP1928442B1 (es)
JP (1) JP2009504761A (es)
KR (1) KR20080038416A (es)
CN (1) CN101242819A (es)
AR (1) AR055609A1 (es)
AT (1) ATE447400T1 (es)
AU (1) AU2006283703A1 (es)
BR (1) BRPI0614943A2 (es)
CA (1) CA2617980A1 (es)
DE (1) DE602006010219D1 (es)
ES (1) ES2336142T3 (es)
MX (1) MX2008001778A (es)
RU (1) RU2008110498A (es)
SG (1) SG140147A1 (es)
TW (1) TW200815009A (es)
WO (1) WO2007024600A2 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2889811B1 (fr) * 2005-08-19 2009-10-09 Sanofi Aventis Sa Association d'un agent hypnotique a duree d'action longue et d'un agent hypnotique a duree d'action courte, composition pharmaceutique la contenant et son application en therapeutique.
BRPI0520797B8 (pt) * 2005-11-18 2021-05-25 Accu Break Tech Inc forma de dosagem farmacêutica comprimida em bicamadas
JP2012505892A (ja) 2008-10-15 2012-03-08 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Mmp−13阻害剤として有用な縮合ヘテロアリールジアミド化合物
CA2738929A1 (en) 2008-10-17 2010-04-22 Boehringer Ingelheim International Gmbh Heteroaryl substituted indole compounds useful as mmp-13 inhibitors
CN102018681A (zh) * 2010-12-10 2011-04-20 荣港生技医药科技(北京)有限公司 一种美乐托宁缓释剂、其制备方法及其应用
US20130060052A1 (en) * 2011-01-17 2013-03-07 Takeda Pharmaceutical Company Limited Orally dispersible tablet
US9120757B2 (en) 2013-03-14 2015-09-01 Epizyme, Inc. Arginine methyltransferase inhibitors and uses thereof
BR112015022785A2 (pt) 2013-03-14 2017-07-18 Epizyme Inc composto; composição farmacêutica; kit ou artigo farmacêutico embalado; método de inibição de uma arginina metil transferase (rmt); método de modulação da expressão genética; método de modulação da transcrição; e método de tratamento de um distúrbio mediado por rmt

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ334868A (en) * 1996-10-21 2001-02-23 Neurosearch As 1-Phenyl-benzimidazole compounds and their use as BAGA-a receptor modulators
US20040258750A1 (en) * 1999-06-28 2004-12-23 Gerard Alaux Timed dual release dosage forms comprising a short acting hypnotic or a salt thereof
AU5721301A (en) * 2000-04-24 2001-11-07 Teva Pharma Zolpidem hemitartrate
GT200600042A (es) * 2005-02-10 2006-09-27 Aventis Pharma Inc Compuestos de bis arilo y heteroarilo sustituido como antagonistas selectivos de 5ht2a

Also Published As

Publication number Publication date
CA2617980A1 (en) 2007-03-01
TW200815009A (en) 2008-04-01
US20080138413A1 (en) 2008-06-12
ES2336142T3 (es) 2010-04-08
KR20080038416A (ko) 2008-05-06
ATE447400T1 (de) 2009-11-15
WO2007024600A3 (en) 2007-05-24
CN101242819A (zh) 2008-08-13
MX2008001778A (es) 2008-04-07
DE602006010219D1 (de) 2009-12-17
EP1928442A2 (en) 2008-06-11
RU2008110498A (ru) 2009-09-27
AU2006283703A1 (en) 2007-03-01
AR055609A1 (es) 2007-08-29
JP2009504761A (ja) 2009-02-05
WO2007024600A2 (en) 2007-03-01
US7618650B2 (en) 2009-11-17
EP1928442B1 (en) 2009-11-04
BRPI0614943A2 (pt) 2011-04-26

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