ATE447400T1 - Kombination aus einem hypnotischen mittel und einer substituierten bis-aryl- und heteroaryl- verbindung und ihre therapeutische anwendung - Google Patents

Kombination aus einem hypnotischen mittel und einer substituierten bis-aryl- und heteroaryl- verbindung und ihre therapeutische anwendung

Info

Publication number
ATE447400T1
ATE447400T1 AT06789813T AT06789813T ATE447400T1 AT E447400 T1 ATE447400 T1 AT E447400T1 AT 06789813 T AT06789813 T AT 06789813T AT 06789813 T AT06789813 T AT 06789813T AT E447400 T1 ATE447400 T1 AT E447400T1
Authority
AT
Austria
Prior art keywords
aryl
combination
therapeutic use
heteroaryl compound
substituted bis
Prior art date
Application number
AT06789813T
Other languages
English (en)
Inventor
Gary T Emmons
Sathapana Kongsamut
Craig N Karson
Corrine M Legoff
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Application granted granted Critical
Publication of ATE447400T1 publication Critical patent/ATE447400T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT06789813T 2005-08-19 2006-08-16 Kombination aus einem hypnotischen mittel und einer substituierten bis-aryl- und heteroaryl- verbindung und ihre therapeutische anwendung ATE447400T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70965505P 2005-08-19 2005-08-19
PCT/US2006/032027 WO2007024600A2 (en) 2005-08-19 2006-08-16 Combination of a hypnotic agent and substituted bis aryl and heteroaryl compound and therapeutic application thereof

Publications (1)

Publication Number Publication Date
ATE447400T1 true ATE447400T1 (de) 2009-11-15

Family

ID=37772166

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06789813T ATE447400T1 (de) 2005-08-19 2006-08-16 Kombination aus einem hypnotischen mittel und einer substituierten bis-aryl- und heteroaryl- verbindung und ihre therapeutische anwendung

Country Status (17)

Country Link
US (1) US7618650B2 (de)
EP (1) EP1928442B1 (de)
JP (1) JP2009504761A (de)
KR (1) KR20080038416A (de)
CN (1) CN101242819A (de)
AR (1) AR055609A1 (de)
AT (1) ATE447400T1 (de)
AU (1) AU2006283703A1 (de)
BR (1) BRPI0614943A2 (de)
CA (1) CA2617980A1 (de)
DE (1) DE602006010219D1 (de)
ES (1) ES2336142T3 (de)
MX (1) MX2008001778A (de)
RU (1) RU2008110498A (de)
SG (1) SG140147A1 (de)
TW (1) TW200815009A (de)
WO (1) WO2007024600A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2889811B1 (fr) * 2005-08-19 2009-10-09 Sanofi Aventis Sa Association d'un agent hypnotique a duree d'action longue et d'un agent hypnotique a duree d'action courte, composition pharmaceutique la contenant et son application en therapeutique.
WO2007058660A1 (en) * 2005-11-18 2007-05-24 Accu-Break Technologies, Inc. Segmented pharmaceutical dosage forms
JP2012505892A (ja) 2008-10-15 2012-03-08 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｍｍｐ−１３阻害剤として有用な縮合ヘテロアリールジアミド化合物
US8785489B2 (en) 2008-10-17 2014-07-22 Boehringer Ingelheim International Gmbh Heteroaryl substituted indole compounds useful as MMP-13 inhibitors
CN102018681A (zh) * 2010-12-10 2011-04-20 荣港生技医药科技（北京）有限公司 一种美乐托宁缓释剂、其制备方法及其应用
US20130060052A1 (en) * 2011-01-17 2013-03-07 Takeda Pharmaceutical Company Limited Orally dispersible tablet
HRP20202008T1 (hr) 2013-03-14 2021-02-19 Epizyme, Inc. Inhibitori arginin-metiltransferaze i njihove uporabe
US9120757B2 (en) 2013-03-14 2015-09-01 Epizyme, Inc. Arginine methyltransferase inhibitors and uses thereof
CN116715633B (zh) * 2022-04-27 2025-08-12 杭州新元素药业股份有限公司 可用于降尿酸的化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1115336C (zh) * 1996-10-21 2003-07-23 神经研究公司 1－苯基－苯并咪唑类化合物及其作为baga－a受体调节剂的用途
US20040258750A1 (en) * 1999-06-28 2004-12-23 Gerard Alaux Timed dual release dosage forms comprising a short acting hypnotic or a salt thereof
SK16372002A3 (sk) * 2000-04-24 2003-04-01 Teva Pharmaceutical Industries Ltd. Zolpidem hemitartrát
GT200600042A (es) * 2005-02-10 2006-09-27 Aventis Pharma Inc Compuestos de bis arilo y heteroarilo sustituido como antagonistas selectivos de 5ht2a

Also Published As

Publication number Publication date
EP1928442A2 (de) 2008-06-11
ES2336142T3 (es) 2010-04-08
JP2009504761A (ja) 2009-02-05
SG140147A1 (en) 2008-03-28
US7618650B2 (en) 2009-11-17
TW200815009A (en) 2008-04-01
BRPI0614943A2 (pt) 2011-04-26
AU2006283703A1 (en) 2007-03-01
WO2007024600A3 (en) 2007-05-24
AR055609A1 (es) 2007-08-29
CA2617980A1 (en) 2007-03-01
WO2007024600A2 (en) 2007-03-01
CN101242819A (zh) 2008-08-13
RU2008110498A (ru) 2009-09-27
US20080138413A1 (en) 2008-06-12
EP1928442B1 (de) 2009-11-04
DE602006010219D1 (de) 2009-12-17
KR20080038416A (ko) 2008-05-06
MX2008001778A (es) 2008-04-07

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