SG11202107732XA - Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells - Google Patents

Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells

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Publication number
SG11202107732XA
SG11202107732XA SG11202107732XA SG11202107732XA SG11202107732XA SG 11202107732X A SG11202107732X A SG 11202107732XA SG 11202107732X A SG11202107732X A SG 11202107732XA SG 11202107732X A SG11202107732X A SG 11202107732XA SG 11202107732X A SG11202107732X A SG 11202107732XA
Authority
SG
Singapore
Prior art keywords
dorsally
pluripotent stem
human pluripotent
oligodendrocyte progenitor
cells
Prior art date
Application number
SG11202107732XA
Other languages
English (en)
Inventor
Kento ONISHI
Nathan C Manley
Craig R Halberstadt
Erik M Whiteley
Original Assignee
Asterias Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asterias Biotherapeutics Inc filed Critical Asterias Biotherapeutics Inc
Publication of SG11202107732XA publication Critical patent/SG11202107732XA/en

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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • C—CHEMISTRY; METALLURGY
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
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    • C12N2500/00—Specific components of cell culture medium
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/113—Acidic fibroblast growth factor (aFGF, FGF-1)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/135—Platelet-derived growth factor [PDGF]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/03—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Developmental Biology & Embryology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
SG11202107732XA 2019-01-23 2020-01-23 Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells SG11202107732XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962796077P 2019-01-23 2019-01-23
PCT/US2020/014834 WO2020154533A1 (en) 2019-01-23 2020-01-23 Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells

Publications (1)

Publication Number Publication Date
SG11202107732XA true SG11202107732XA (en) 2021-08-30

Family

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Country Status (9)

Country Link
US (3) US11603518B2 (cg-RX-API-DMAC7.html)
EP (1) EP3914264A4 (cg-RX-API-DMAC7.html)
JP (2) JP7469317B2 (cg-RX-API-DMAC7.html)
KR (2) KR102910994B1 (cg-RX-API-DMAC7.html)
CN (2) CN120060141A (cg-RX-API-DMAC7.html)
AU (2) AU2020210757B2 (cg-RX-API-DMAC7.html)
CA (1) CA3127213A1 (cg-RX-API-DMAC7.html)
SG (1) SG11202107732XA (cg-RX-API-DMAC7.html)
WO (1) WO2020154533A1 (cg-RX-API-DMAC7.html)

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JP2022520722A (ja) 2022-04-01
US20260167925A1 (en) 2026-06-18
KR20210121112A (ko) 2021-10-07
KR102910994B1 (ko) 2026-01-12
CN113474451A (zh) 2021-10-01
EP3914264A4 (en) 2022-11-23
US11603518B2 (en) 2023-03-14
WO2020154533A1 (en) 2020-07-30
CA3127213A1 (en) 2020-07-30
JP2024096785A (ja) 2024-07-17
US20200231932A1 (en) 2020-07-23
AU2020210757A1 (en) 2021-08-05
US20230139899A1 (en) 2023-05-04
EP3914264A1 (en) 2021-12-01
KR20260020476A (ko) 2026-02-11
CN113474451B (zh) 2025-06-10
AU2026204574A1 (en) 2026-07-02
JP7469317B2 (ja) 2024-04-16
AU2020210757B2 (en) 2026-04-16
CN120060141A (zh) 2025-05-30

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