SG11202104699TA - Use of il-1 beta antibodies in the treatment or prevention of myelodysplastic syndrome - Google Patents

Use of il-1 beta antibodies in the treatment or prevention of myelodysplastic syndrome

Info

Publication number
SG11202104699TA
SG11202104699TA SG11202104699TA SG11202104699TA SG11202104699TA SG 11202104699T A SG11202104699T A SG 11202104699TA SG 11202104699T A SG11202104699T A SG 11202104699TA SG 11202104699T A SG11202104699T A SG 11202104699TA SG 11202104699T A SG11202104699T A SG 11202104699TA
Authority
SG
Singapore
Prior art keywords
prevention
treatment
myelodysplastic syndrome
beta antibodies
antibodies
Prior art date
Application number
SG11202104699TA
Other languages
English (en)
Inventor
Andreas Bruederle
Connie Wong
K Gary Vanasse
Mikael Rinne
Jean Regard
Anshu Marathe
Haiying Sun
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SG11202104699TA publication Critical patent/SG11202104699TA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/245—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11202104699TA 2018-12-21 2019-12-18 Use of il-1 beta antibodies in the treatment or prevention of myelodysplastic syndrome SG11202104699TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862783568P 2018-12-21 2018-12-21
PCT/IB2019/001435 WO2020128636A1 (en) 2018-12-21 2019-12-18 Use of il-1 beta antibodies in the treatment or prevention of myelodysplastic syndrome

Publications (1)

Publication Number Publication Date
SG11202104699TA true SG11202104699TA (en) 2021-07-29

Family

ID=70050161

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202104699TA SG11202104699TA (en) 2018-12-21 2019-12-18 Use of il-1 beta antibodies in the treatment or prevention of myelodysplastic syndrome

Country Status (14)

Country Link
US (2) US20200369762A1 (ja)
EP (1) EP3898675A1 (ja)
JP (1) JP2022516850A (ja)
KR (1) KR20210107730A (ja)
CN (1) CN113227137A (ja)
AU (1) AU2019406840A1 (ja)
BR (1) BR112021011351A2 (ja)
CA (1) CA3119584A1 (ja)
CL (1) CL2021001619A1 (ja)
IL (1) IL283518A (ja)
MX (1) MX2021007488A (ja)
SG (1) SG11202104699TA (ja)
TW (1) TW202039555A (ja)
WO (1) WO2020128636A1 (ja)

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US20230057071A1 (en) * 2019-12-20 2023-02-23 Novartis Ag Combination of anti tim-3 antibody mbg453 and anti tgf-beta antibody nis793, with or without decitabine or the anti pd-1 antibody spartalizumab, for treating myelofibrosis and myelodysplastic syndrome

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Also Published As

Publication number Publication date
BR112021011351A2 (pt) 2021-11-16
JP2022516850A (ja) 2022-03-03
WO2020128636A8 (en) 2021-07-01
KR20210107730A (ko) 2021-09-01
WO2020128636A1 (en) 2020-06-25
EP3898675A1 (en) 2021-10-27
CA3119584A1 (en) 2020-06-25
IL283518A (en) 2021-07-29
US20200369762A1 (en) 2020-11-26
CL2021001619A1 (es) 2022-02-11
US20230088070A1 (en) 2023-03-23
TW202039555A (zh) 2020-11-01
AU2019406840A1 (en) 2021-06-03
MX2021007488A (es) 2021-08-05
CN113227137A (zh) 2021-08-06

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