SG11202011837UA - Diverse antigen binding domains, novel platforms and other enhancements for cellular therapy - Google Patents
Diverse antigen binding domains, novel platforms and other enhancements for cellular therapyInfo
- Publication number
- SG11202011837UA SG11202011837UA SG11202011837UA SG11202011837UA SG11202011837UA SG 11202011837U A SG11202011837U A SG 11202011837UA SG 11202011837U A SG11202011837U A SG 11202011837UA SG 11202011837U A SG11202011837U A SG 11202011837UA SG 11202011837U A SG11202011837U A SG 11202011837UA
- Authority
- SG
- Singapore
- Prior art keywords
- enhancements
- antigen binding
- binding domains
- cellular therapy
- diverse antigen
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 238000002659 cell therapy Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
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- C—CHEMISTRY; METALLURGY
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2319/00—Fusion polypeptide
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862679741P | 2018-06-01 | 2018-06-01 | |
PCT/US2019/035096 WO2019232503A1 (en) | 2018-06-01 | 2019-06-01 | Diverse antigen binding domains, novel platforms and other enhancements for cellular therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202011837UA true SG11202011837UA (en) | 2020-12-30 |
Family
ID=68697132
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202011837UA SG11202011837UA (en) | 2018-06-01 | 2019-06-01 | Diverse antigen binding domains, novel platforms and other enhancements for cellular therapy |
Country Status (15)
Country | Link |
---|---|
US (1) | US20210137977A1 (zh) |
EP (1) | EP3802822A4 (zh) |
JP (1) | JP2021525509A (zh) |
KR (1) | KR20210057705A (zh) |
CN (1) | CN113286879A (zh) |
AU (1) | AU2019279084A1 (zh) |
BR (1) | BR112020024246A2 (zh) |
CA (1) | CA3101510A1 (zh) |
CO (1) | CO2020016586A2 (zh) |
EA (1) | EA202092945A1 (zh) |
IL (1) | IL279100A (zh) |
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BR112019025667A2 (pt) | 2017-06-05 | 2020-09-01 | Mie University | proteína de ligação ao antígeno que reconhece o peptídeo derivado de mage-a4 |
JP2021500861A (ja) * | 2017-09-27 | 2021-01-14 | ユニバーシティ オブ サザン カリフォルニア | 共刺激のための新規のプラットフォーム、新規のcar設計、および養子細胞療法のための他の増強 |
WO2020127618A1 (en) * | 2018-12-21 | 2020-06-25 | F. Hoffmann-La Roche Ag | Tumor-targeted agonistic cd28 antigen binding molecules |
EP3733707A1 (en) * | 2019-04-30 | 2020-11-04 | Celyad S.A. | Car t-cells targeting bcma and uses thereof |
EP3842461A1 (en) * | 2019-12-23 | 2021-06-30 | Albert-Ludwigs-Universität Freiburg | Chimeric antigen receptors that bind to prostate specific membrane antigen |
AU2021205249A1 (en) * | 2020-01-08 | 2022-07-21 | Board Of Regents, The University Of Texas System | A method of engineering natural killer cells to target CD70-positive tumors |
US20230149462A1 (en) * | 2020-04-10 | 2023-05-18 | Juno Therapeutics, Inc. | Methods and uses related to cell therapy engineered with a chimeric antigen receptor targeting b-cell maturation antigen |
EP4138865A4 (en) * | 2020-04-24 | 2024-05-22 | Memorial Sloan Kettering Cancer Center | CHIMERIC ANTIGEN RECEPTORS DIRECTED TO CD19 AND USE THEREOF |
AR122014A1 (es) | 2020-05-06 | 2022-08-03 | Crispr Therapeutics Ag | Receptor de antígenos quimérico enmascarado específico para la proteína tirosina cinasa de tipo 7 (ptk7) y células inmunitarias que expresan el mismo |
US11919944B2 (en) | 2020-05-11 | 2024-03-05 | Augmenta Biosciences, Inc. | Antibodies for SARS-CoV-2 and uses thereof |
WO2022031882A1 (en) * | 2020-08-06 | 2022-02-10 | Stelexis Therapeutics, Llc | Il-8 antibodies and methods of use thereof |
CA3201008A1 (en) * | 2020-12-02 | 2022-06-09 | Shanghai Cellular Biopharmaceutical Group Ltd. | Bcma-targeted chimeric antigen receptors |
WO2022170126A2 (en) * | 2021-02-05 | 2022-08-11 | Adagio Therapeutics, Inc. | Compounds specific to coronavirus s protein and uses thereof |
CN115491358A (zh) * | 2021-06-17 | 2022-12-20 | 复星凯特生物科技有限公司 | 一种靶向b7-h3和folr1双打靶点car t的制备及应用 |
WO2023056312A1 (en) * | 2021-09-29 | 2023-04-06 | Modex Therapeutics | Antigen binding polypeptides, antigen binding polypeptide complexes and methods of use thereof |
US20230310605A1 (en) | 2021-10-28 | 2023-10-05 | Lyell Immunopharma, Inc. | Methods for culturing cells expressing ror1-binding protein |
CN114106199B (zh) * | 2021-11-19 | 2022-07-12 | 广州百暨基因科技有限公司 | 靶向adgre2的嵌合抗原受体及其应用 |
US20230322928A1 (en) * | 2022-03-07 | 2023-10-12 | Medimmune, Llc | Treatment methods using ctla-4 and pd-1 bispecific antibodies |
WO2023175069A1 (en) * | 2022-03-16 | 2023-09-21 | Medigene Immunotherapies Gmbh | Tcr constant region pairing library for pramevld tcrs |
WO2023175070A1 (en) * | 2022-03-16 | 2023-09-21 | Medigene Immunotherapies Gmbh | Tcr constant region pairing library |
GB202208119D0 (en) * | 2022-06-01 | 2022-07-13 | Univ Oslo Hf | Anti-steap1 car |
WO2024064958A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
WO2024064952A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells overexpressing c-jun |
WO2024077174A1 (en) | 2022-10-05 | 2024-04-11 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
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WO2013033626A2 (en) * | 2011-08-31 | 2013-03-07 | Trustees Of Dartmouth College | Nkp30 receptor targeted therapeutics |
EP3131927B8 (en) * | 2014-04-14 | 2020-12-23 | Cellectis | Bcma (cd269) specific chimeric antigen receptors for cancer immunotherapy |
WO2016174852A1 (ja) * | 2015-04-30 | 2016-11-03 | 株式会社デンソー | 蒸発器 |
CA2990177A1 (en) * | 2015-06-25 | 2016-12-29 | Icell Gene Therapeutics Llc | Chimeric antigen receptors (cars), compositions and methods thereof |
RU2022103665A (ru) * | 2015-10-23 | 2022-03-05 | Еурека Терапьютикс, Инк. | Химерные конструкции антитело/t-клеточный рецептор и их применения |
JP7208010B2 (ja) * | 2016-03-29 | 2023-01-18 | ユニバーシティ オブ サザン カリフォルニア | 癌を標的とするキメラ抗原受容体 |
WO2018102795A2 (en) * | 2016-12-02 | 2018-06-07 | University Of Southern California | Synthetic immune receptors and methods of use thereof |
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2019
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2020
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CO2020016586A2 (es) | 2021-01-29 |
US20210137977A1 (en) | 2021-05-13 |
KR20210057705A (ko) | 2021-05-21 |
BR112020024246A2 (pt) | 2021-03-02 |
EP3802822A4 (en) | 2022-03-09 |
IL279100A (en) | 2021-01-31 |
AU2019279084A1 (en) | 2020-12-17 |
CN113286879A (zh) | 2021-08-20 |
MX2020012927A (es) | 2021-03-25 |
CA3101510A1 (en) | 2019-12-05 |
EA202092945A1 (ru) | 2021-04-29 |
WO2019232503A1 (en) | 2019-12-05 |
TW202018083A (zh) | 2020-05-16 |
EP3802822A1 (en) | 2021-04-14 |
JP2021525509A (ja) | 2021-09-27 |
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