SG11202010385RA - 2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative of novel compound for directly inhibiting asm activity, and use thereof - Google Patents
2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative of novel compound for directly inhibiting asm activity, and use thereofInfo
- Publication number
- SG11202010385RA SG11202010385RA SG11202010385RA SG11202010385RA SG11202010385RA SG 11202010385R A SG11202010385R A SG 11202010385RA SG 11202010385R A SG11202010385R A SG 11202010385RA SG 11202010385R A SG11202010385R A SG 11202010385RA SG 11202010385R A SG11202010385R A SG 11202010385RA
- Authority
- SG
- Singapore
- Prior art keywords
- triazole
- propane
- amino
- novel compound
- diol derivative
- Prior art date
Links
- BWPMQDZKOHOPNN-UHFFFAOYSA-N 2-amino-2-(2H-triazol-4-yl)propane-1,3-diol Chemical class NC(CO)(CO)C=1N=NNC=1 BWPMQDZKOHOPNN-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/03—Organic compounds
- A23L29/045—Organic compounds containing nitrogen as heteroatom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4192—1,2,3-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020180050215A KR102017324B1 (ko) | 2018-04-30 | 2018-04-30 | 신규한 asm 활성 직접 억제 화합물 2-아미노-2-(1,2,3-트리아졸-4-일)프로판-1,3-디올 유도체 및 이의 용도 |
| PCT/KR2019/005019 WO2019212196A1 (ko) | 2018-04-30 | 2019-04-25 | 신규한 asm 활성 직접 억제 화합물 2-아미노-2-(1,2,3-트리아졸-4-일)프로판-1,3-디올 유도체 및 이의 용도 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202010385RA true SG11202010385RA (en) | 2020-11-27 |
Family
ID=67951278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202010385RA SG11202010385RA (en) | 2018-04-30 | 2019-04-25 | 2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative of novel compound for directly inhibiting asm activity, and use thereof |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20210188784A1 (zh) |
| EP (1) | EP3789380A4 (zh) |
| JP (1) | JP7178029B2 (zh) |
| KR (1) | KR102017324B1 (zh) |
| CN (1) | CN112351974B (zh) |
| AU (1) | AU2019264073B2 (zh) |
| BR (1) | BR112020022141A2 (zh) |
| CA (1) | CA3097685C (zh) |
| IL (1) | IL278139B2 (zh) |
| MX (1) | MX2020011490A (zh) |
| PH (1) | PH12020551751A1 (zh) |
| RU (1) | RU2759856C1 (zh) |
| SG (1) | SG11202010385RA (zh) |
| WO (1) | WO2019212196A1 (zh) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102701244B1 (ko) | 2017-10-23 | 2024-09-02 | 에피트래커, 인코포레이티드 | 지방산 유사체 및 대사 증후군 관련 병태 치료에서의 그의 용도 |
| CA3099482A1 (en) | 2018-05-23 | 2019-11-28 | Epitracker, Inc. | Compositions and methods for diagnosis and treatment of conditions related to the quality of aging and longevity |
| JP7404382B2 (ja) * | 2019-03-04 | 2023-12-25 | エピトラッカー インコーポレイテッド | 脂肪酸アナログ、ならびに認知機能障害、行動症状および慢性疼痛の処置におけるそれらの使用 |
| JP2023542964A (ja) * | 2020-09-22 | 2023-10-12 | 慶北大学校 産学連携財団 | グレリン受容体作用剤としてのトリアゾール化合物の用途 |
| TWI824534B (zh) * | 2021-05-27 | 2023-12-01 | 南韓商梨樹愛博思股份有限公司 | 與酸性鞘磷脂酶蛋白特異性結合的抗體 |
| KR102541579B1 (ko) * | 2021-09-15 | 2023-06-13 | 주식회사 넥스트젠바이오사이언스 | S1pr1 및 s1pr4에 대한 기능적 저해제로 작용하는 국소 분절 사구체경화증 예방 또는 치료용 약학적 조성물 |
| WO2023043024A1 (en) * | 2021-09-15 | 2023-03-23 | Nextgen Bioscience | Pharmaceutical composition for preventing or treating interstitial fibrosis and tubular atrophy as a functional antagonist for s1pr1 and s1pr4 |
| KR102541578B1 (ko) * | 2022-03-23 | 2023-06-13 | 주식회사 넥스트젠바이오사이언스 | S1pr1과 s1pr4에 대한 기능적 저해제로 작용하는 염증성 장질환의 예방 또는 치료용 약학적 조성물 |
| KR20240126916A (ko) * | 2023-02-14 | 2024-08-22 | 경북대학교 산학협력단 | Asm 단백질 또는 이의 단편을 포함하는 퇴행성 신경질환 또는 우울증 예방 또는 치료용 조성물 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0722077D0 (en) * | 2007-11-09 | 2007-12-19 | Smithkline Beecham Corp | Compounds |
| WO2010017408A1 (en) * | 2008-08-06 | 2010-02-11 | The Buck Institute For Age Research | Caspase inhibitors and uses thereof |
| CA2740484C (en) * | 2008-10-17 | 2021-09-21 | Akaal Pharma Pty Ltd | S1p receptors modulators and their use thereof |
| KR101521117B1 (ko) | 2013-05-07 | 2015-05-18 | 경북대학교 산학협력단 | Ａｓｍ 억제제를 유효성분으로 포함하는 퇴행성 신경질환의 예방 또는 치료용 조성물 |
| WO2015188368A1 (en) * | 2014-06-13 | 2015-12-17 | Merck Sharp & Dohme Corp. | Pyrrolo[2,3-c]pyridines as imaging agents for neurofibrilary tangles |
| KR101830244B1 (ko) * | 2016-01-20 | 2018-02-21 | 서울대학교 산학협력단 | 신규한 헤테로방향족 고리 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 s1p 수용체 관련 질환의 예방 또는 치료용 약학적 조성물 |
| KR20180036318A (ko) * | 2016-09-30 | 2018-04-09 | 경북대학교 산학협력단 | 2-아미노-2-(1-도데실-1h-1,2,3-트리아졸-4-일)프로판-1,3-디올 유도체를 유효성분으로 포함하는 퇴행성 신경질환 및 우울증 예방 또는 치료용 약학적 조성물 |
| KR102130999B1 (ko) | 2016-11-04 | 2020-07-09 | 주식회사 케이티 | 무선 통신에서 멀티 빔 기반 스케줄링 요청을 수행하는 방법 및 장치 |
| KR101811436B1 (ko) * | 2017-04-28 | 2017-12-21 | 경북대학교 산학협력단 | 신규 화합물 2-아미노-2-(1-(2-(2-히드록시에톡시)에틸)-1h-1,2,3-트리아졸-4-일)프로판-1,3-디올 유도체 및 이의 용도 |
-
2018
- 2018-04-30 KR KR1020180050215A patent/KR102017324B1/ko active IP Right Grant
-
2019
- 2019-04-25 BR BR112020022141-4A patent/BR112020022141A2/pt unknown
- 2019-04-25 CN CN201980044399.4A patent/CN112351974B/zh active Active
- 2019-04-25 WO PCT/KR2019/005019 patent/WO2019212196A1/ko unknown
- 2019-04-25 EP EP19796973.6A patent/EP3789380A4/en active Pending
- 2019-04-25 US US17/048,672 patent/US20210188784A1/en active Pending
- 2019-04-25 CA CA3097685A patent/CA3097685C/en active Active
- 2019-04-25 JP JP2020561831A patent/JP7178029B2/ja active Active
- 2019-04-25 AU AU2019264073A patent/AU2019264073B2/en active Active
- 2019-04-25 MX MX2020011490A patent/MX2020011490A/es unknown
- 2019-04-25 SG SG11202010385RA patent/SG11202010385RA/en unknown
- 2019-04-25 IL IL278139A patent/IL278139B2/en unknown
- 2019-04-25 RU RU2020138684A patent/RU2759856C1/ru active
-
2020
- 2020-10-21 PH PH12020551751A patent/PH12020551751A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20210188784A1 (en) | 2021-06-24 |
| PH12020551751A1 (en) | 2021-07-26 |
| IL278139B1 (en) | 2023-11-01 |
| EP3789380A1 (en) | 2021-03-10 |
| EP3789380A4 (en) | 2021-12-22 |
| CA3097685A1 (en) | 2019-11-07 |
| CN112351974A (zh) | 2021-02-09 |
| IL278139A (zh) | 2020-12-31 |
| JP2022514722A (ja) | 2022-02-15 |
| AU2019264073B2 (en) | 2022-03-31 |
| CA3097685C (en) | 2023-10-03 |
| MX2020011490A (es) | 2021-02-18 |
| WO2019212196A1 (ko) | 2019-11-07 |
| RU2759856C1 (ru) | 2021-11-18 |
| KR102017324B1 (ko) | 2019-09-02 |
| BR112020022141A2 (pt) | 2021-01-26 |
| JP7178029B2 (ja) | 2022-11-25 |
| CN112351974B (zh) | 2024-01-26 |
| IL278139B2 (en) | 2024-03-01 |
| AU2019264073A1 (en) | 2020-11-26 |
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