SG11202010385RA - 2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative of novel compound for directly inhibiting asm activity, and use thereof - Google Patents
2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative of novel compound for directly inhibiting asm activity, and use thereofInfo
- Publication number
- SG11202010385RA SG11202010385RA SG11202010385RA SG11202010385RA SG11202010385RA SG 11202010385R A SG11202010385R A SG 11202010385RA SG 11202010385R A SG11202010385R A SG 11202010385RA SG 11202010385R A SG11202010385R A SG 11202010385RA SG 11202010385R A SG11202010385R A SG 11202010385RA
- Authority
- SG
- Singapore
- Prior art keywords
- triazole
- propane
- amino
- novel compound
- diol derivative
- Prior art date
Links
- BWPMQDZKOHOPNN-UHFFFAOYSA-N 2-amino-2-(2H-triazol-4-yl)propane-1,3-diol Chemical class NC(CO)(CO)C=1N=NNC=1 BWPMQDZKOHOPNN-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/03—Organic compounds
- A23L29/045—Organic compounds containing nitrogen as heteroatom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4192—1,2,3-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020180050215A KR102017324B1 (en) | 2018-04-30 | 2018-04-30 | Novel ASM direct inhibition compound 2-amino-2-(1,2,3-triazol-4-yl)propane-1,3-diol derivatives and uses thereof |
| PCT/KR2019/005019 WO2019212196A1 (en) | 2018-04-30 | 2019-04-25 | 2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative of novel compound for directly inhibiting asm activity, and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202010385RA true SG11202010385RA (en) | 2020-11-27 |
Family
ID=67951278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202010385RA SG11202010385RA (en) | 2018-04-30 | 2019-04-25 | 2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative of novel compound for directly inhibiting asm activity, and use thereof |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20210188784A1 (en) |
| EP (1) | EP3789380A4 (en) |
| JP (1) | JP7178029B2 (en) |
| KR (1) | KR102017324B1 (en) |
| CN (1) | CN112351974B (en) |
| AU (1) | AU2019264073B2 (en) |
| BR (1) | BR112020022141A2 (en) |
| CA (1) | CA3097685C (en) |
| IL (1) | IL278139B2 (en) |
| MX (1) | MX2020011490A (en) |
| PH (1) | PH12020551751A1 (en) |
| RU (1) | RU2759856C1 (en) |
| SG (1) | SG11202010385RA (en) |
| WO (1) | WO2019212196A1 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7312184B2 (en) | 2017-10-23 | 2023-07-20 | エピトラッカー インコーポレイテッド | Fatty acid analogues and their use in treating symptoms associated with metabolic syndrome |
| JP2021525249A (en) | 2018-05-23 | 2021-09-24 | エピトラッカー インコーポレイテッドＥｐｉｔｒａｃｋｅｒ， Ｉｎｃ． | Compositions and Methods for Diagnosis and Treatment of Conditions Related to Aging and Long-Term Quality |
| JP7404382B2 (en) * | 2019-03-04 | 2023-12-25 | エピトラッカー インコーポレイテッド | Fatty acid analogs and their use in the treatment of cognitive dysfunction, behavioral symptoms and chronic pain |
| KR20220039625A (en) * | 2020-09-22 | 2022-03-29 | 경북대학교 산학협력단 | Use of triazol compounds as ghrelin receptor agonists |
| EP4349866A1 (en) * | 2021-05-27 | 2024-04-10 | Isu Abxis Co., Ltd. | Antibody specifically binding to asm protein |
| WO2023043024A1 (en) * | 2021-09-15 | 2023-03-23 | Nextgen Bioscience | Pharmaceutical composition for preventing or treating interstitial fibrosis and tubular atrophy as a functional antagonist for s1pr1 and s1pr4 |
| KR102541579B1 (en) * | 2021-09-15 | 2023-06-13 | 주식회사 넥스트젠바이오사이언스 | Pharmaceutical composition for preventing or treating focal segmental glomerulosclerosis acting as a functional inhibitor for S1PR1 and S1PR4 |
| JP7465041B1 (en) | 2022-03-23 | 2024-04-10 | ネクストジェン バイオサイエンス カンパニー リミテッド | Pharmaceutical composition for preventing or treating inflammatory bowel disease acting as a functional antagonist of S1PR1 and S1PR4 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0722077D0 (en) * | 2007-11-09 | 2007-12-19 | Smithkline Beecham Corp | Compounds |
| US8518942B2 (en) * | 2008-08-06 | 2013-08-27 | Buck Institute For Research On Aging | Caspase inhibitors and uses thereof |
| NZ592748A (en) * | 2008-10-17 | 2013-01-25 | Akaal Pharma Pty Ltd | 2-Amino-(oxadiazol-3-yl)-benzofuran derivatives and their use as S1P receptor modulators |
| KR101521117B1 (en) | 2013-05-07 | 2015-05-18 | 경북대학교 산학협력단 | Composition for preventing or treating neurodegenerative disorder comprising acid sphingomyelinase inhibitor |
| WO2015188368A1 (en) * | 2014-06-13 | 2015-12-17 | Merck Sharp & Dohme Corp. | Pyrrolo[2,3-c]pyridines as imaging agents for neurofibrilary tangles |
| KR101830244B1 (en) * | 2016-01-20 | 2018-02-21 | 서울대학교 산학협력단 | Novel heteroaromatic ring compound, preparation method thereof, and pharmaceutical composition for use in preventing or treating S1P receptor relating diseases containing the same as an active ingredient |
| KR20180036318A (en) * | 2016-09-30 | 2018-04-09 | 경북대학교 산학협력단 | Composition for preventing or treating neurodegenerative disease comprising derivatives of 2-amino-2-(1-dodecyl-1H-1,2,3-triazol-4-yl)propane-1,3-diol |
| KR102130999B1 (en) | 2016-11-04 | 2020-07-09 | 주식회사 케이티 | MAethods of scheduling request based on multi-beam in wireless networks and Apparatuses thereof |
| KR101811436B1 (en) * | 2017-04-28 | 2017-12-21 | 경북대학교 산학협력단 | Novel compound 2-amino-2-(1-(2-(2-hydroxyethoxy)ethyl)-1H-1,2,3-triazol-4-yl)propane-1,3-diol and use thereof |
-
2018
- 2018-04-30 KR KR1020180050215A patent/KR102017324B1/en active IP Right Grant
-
2019
- 2019-04-25 AU AU2019264073A patent/AU2019264073B2/en active Active
- 2019-04-25 MX MX2020011490A patent/MX2020011490A/en unknown
- 2019-04-25 RU RU2020138684A patent/RU2759856C1/en active
- 2019-04-25 US US17/048,672 patent/US20210188784A1/en active Pending
- 2019-04-25 EP EP19796973.6A patent/EP3789380A4/en active Pending
- 2019-04-25 SG SG11202010385RA patent/SG11202010385RA/en unknown
- 2019-04-25 IL IL278139A patent/IL278139B2/en unknown
- 2019-04-25 JP JP2020561831A patent/JP7178029B2/en active Active
- 2019-04-25 CN CN201980044399.4A patent/CN112351974B/en active Active
- 2019-04-25 CA CA3097685A patent/CA3097685C/en active Active
- 2019-04-25 WO PCT/KR2019/005019 patent/WO2019212196A1/en unknown
- 2019-04-25 BR BR112020022141-4A patent/BR112020022141A2/en unknown
-
2020
- 2020-10-21 PH PH12020551751A patent/PH12020551751A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112020022141A2 (en) | 2021-01-26 |
| CN112351974A (en) | 2021-02-09 |
| PH12020551751A1 (en) | 2021-07-26 |
| RU2759856C1 (en) | 2021-11-18 |
| AU2019264073A1 (en) | 2020-11-26 |
| JP7178029B2 (en) | 2022-11-25 |
| WO2019212196A1 (en) | 2019-11-07 |
| KR102017324B1 (en) | 2019-09-02 |
| US20210188784A1 (en) | 2021-06-24 |
| EP3789380A4 (en) | 2021-12-22 |
| IL278139B2 (en) | 2024-03-01 |
| JP2022514722A (en) | 2022-02-15 |
| MX2020011490A (en) | 2021-02-18 |
| CN112351974B (en) | 2024-01-26 |
| CA3097685A1 (en) | 2019-11-07 |
| EP3789380A1 (en) | 2021-03-10 |
| AU2019264073B2 (en) | 2022-03-31 |
| IL278139A (en) | 2020-12-31 |
| CA3097685C (en) | 2023-10-03 |
| IL278139B1 (en) | 2023-11-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SG11202010385RA (en) | 2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative of novel compound for directly inhibiting asm activity, and use thereof | |
| IL279256A (en) | Sulfonimidamide compounds as inhibitors of interleukin-1 activity | |
| EA201791444A1 (en) | 5-Fluoro-4-Imino-3- (Alkyl / Substituted Alkyl) -1- (arylsulfonyl) -3,4-DIHYDROPYRIMIDIN-2 (1H) -ON As Seed Treatment Means | |
| IL267961B1 (en) | Chemical compounds as inhibitors of interleukin-1 activity | |
| HK1248235A1 (en) | Benzimidazole and imadazopyridine carboximidamide compounds having activity as inhibitors of indoleamine 2,3-dioxygenase | |
| EP3372595A4 (en) | Oxime group-containing condensed heterocyclic compound or salts thereof and agricultural and horticultural insecticide containing said compound, and method for using same | |
| MX2018000050A (en) | Phenoxyhalogenphenylamidines and the use thereof as fungicides. | |
| PH12018501543A1 (en) | Fungicidal composition | |
| MX2022007436A (en) | Autotaxin inhibitors and uses thereof. | |
| MX2017001897A (en) | Condensed 11-member ring compound and agriculture and horticultural fungicide comprising same. | |
| EP3504185A4 (en) | Novel substituted n'-hydroxycarbamimidoyl-1,2,5-oxadiazole compounds as indoleamine 2,3-dioxygenase (ido) inhibitors | |
| MX2017014459A (en) | Thioether compounds as nitrification inhibitors. | |
| PH12017501135A1 (en) | Active compound combinations | |
| PH12017501136A1 (en) | Active compound combinations | |
| PH12017501110A1 (en) | Active compound combinations comprising a (thio)carboxamide derivative and fungicidal compound(s) | |
| PH12017501137A1 (en) | Active compound combinations | |
| EP3585774A4 (en) | Novel substituted sulfoximine compounds as indoleamine 2,3-dioxygenase (ido) inhibitors | |
| EP3661909A4 (en) | Novel substituted phenyl compounds as indoleamine 2,3-dioxygenase (ido) inhibitors | |
| EP3694502A4 (en) | Novel substituted cyclobutylbenzene compounds as indoleamine 2,3-dioxygenase (ido) inhibitors | |
| EP3560928A4 (en) | Fused imidazole compound having indoleamine 2,3-dioxygenase inhibitory activity | |
| EP3544965A4 (en) | Sulfoximine, sulfonimidamide, sulfondiimine and diimidosulfonamide compounds as inhibitors of indoleamine 2, 3-dioxygenase | |
| NZ765435A (en) | Polymorphs | |
| EP3600299A4 (en) | Novel substituted n'-hydroxycarbamimidoyl-1,2,5-oxadiazole compounds as indoleamine 2,3-dioxygenase (ido) inhibitors | |
| IL257168B (en) | Application of 7-carboxybenzo[1,2,3]thiadiazole amides as plant stimulants | |
| IT201700122788A1 (en) | PLANT FOR THE MANAGEMENT OF TRAYS |