SG11202008579UA - Anti-phf-tau antibodies and uses thereof - Google Patents
Anti-phf-tau antibodies and uses thereofInfo
- Publication number
- SG11202008579UA SG11202008579UA SG11202008579UA SG11202008579UA SG11202008579UA SG 11202008579U A SG11202008579U A SG 11202008579UA SG 11202008579U A SG11202008579U A SG 11202008579UA SG 11202008579U A SG11202008579U A SG 11202008579UA SG 11202008579U A SG11202008579U A SG 11202008579UA
- Authority
- SG
- Singapore
- Prior art keywords
- phf
- tau antibodies
- tau
- antibodies
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/563—Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2835—Movement disorders, e.g. Parkinson, Huntington, Tourette
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Plant Pathology (AREA)
- Psychology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862638535P | 2018-03-05 | 2018-03-05 | |
PCT/IB2019/051748 WO2019171259A1 (fr) | 2018-03-05 | 2019-03-04 | Anticorps anti-phf-tau et leurs utilisations |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202008579UA true SG11202008579UA (en) | 2020-10-29 |
Family
ID=67767358
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202008579UA SG11202008579UA (en) | 2018-03-05 | 2019-03-04 | Anti-phf-tau antibodies and uses thereof |
Country Status (17)
Country | Link |
---|---|
US (2) | US10633435B2 (fr) |
EP (1) | EP3774888A4 (fr) |
JP (2) | JP7362636B2 (fr) |
KR (1) | KR20200130350A (fr) |
CN (1) | CN112105639A (fr) |
AU (1) | AU2019232631A1 (fr) |
BR (1) | BR112020018112A2 (fr) |
CA (1) | CA3093200A1 (fr) |
EA (1) | EA202092088A1 (fr) |
IL (1) | IL277075A (fr) |
JO (1) | JOP20200215A1 (fr) |
MA (1) | MA52235A (fr) |
MX (1) | MX2020009277A (fr) |
PH (1) | PH12020551373A1 (fr) |
SG (1) | SG11202008579UA (fr) |
TW (1) | TW201946654A (fr) |
WO (1) | WO2019171259A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL307170A (en) | 2021-03-26 | 2023-11-01 | Janssen Biotech Inc | Anti-tau antibodies and their uses |
WO2023092004A1 (fr) | 2021-11-17 | 2023-05-25 | Voyager Therapeutics, Inc. | Compositions et méthodes pour le traitement de troubles liés à tau |
TW202345899A (zh) * | 2022-03-11 | 2023-12-01 | 比利時商健生藥品公司 | 多特異性抗體及其用途(三) |
TW202346355A (zh) * | 2022-03-11 | 2023-12-01 | 比利時商健生藥品公司 | 多特異性抗體及其用途(二) |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
US7408027B1 (en) * | 1991-12-06 | 2008-08-05 | Max-Planck-Gesellschaft Zur Forderung Der Wissenchaften | Tools for the diagnosis and treatment of Alzheimer's disease |
JP3992729B2 (ja) * | 1993-12-21 | 2007-10-17 | インノジェネティクス・エヌ・ブイ | Phf−タウに特異的なモノクローナル抗体、これらを分泌するハイブリドーマ、これらの抗体による抗原認識及びこれらの応用 |
ES2274869T3 (es) * | 2000-01-24 | 2007-06-01 | Innogenetics N.V. | Diagnostico de tauopatias determinando la relacion tau/fosfotau. |
MXPA03010804A (es) | 2001-06-01 | 2004-11-22 | Cornell Res Foundation Inc | Anticuerpos modificados para antigeno de membrana especifico de la prostata y usos de los mismos. |
MXPA05000511A (es) | 2001-07-12 | 2005-09-30 | Jefferson Foote | Anticuepros super humanizados. |
US20050025763A1 (en) * | 2003-05-08 | 2005-02-03 | Protein Design Laboratories, Inc. | Therapeutic use of anti-CS1 antibodies |
EP2221315A1 (fr) | 2003-12-04 | 2010-08-25 | Xencor, Inc. | Procédés de génération de protéines variantes avec un contenu amélioré de fil hôte et compositions associées |
PT2662390T (pt) | 2004-06-21 | 2017-10-09 | Squibb & Sons Llc | Anticorpos contra recetor 1 do interferão alfa e as suas utilizações |
EP1749839A1 (fr) * | 2005-07-22 | 2007-02-07 | Novoplant GmbH | Polypeptides de liaison d'antigènes F4 (K88) fimbriae |
EP1973951A2 (fr) * | 2005-12-02 | 2008-10-01 | Genentech, Inc. | Polypeptides de liaison avec des sequences de diversite limitees |
AU2008343589A1 (en) | 2007-12-19 | 2009-07-09 | Centocor Ortho Biotech Inc. | Design and generation of human de novo pIX phage display libraries via fusion to pIX or pVII, vectors, antibodies and methods |
WO2010045340A1 (fr) | 2008-10-14 | 2010-04-22 | Centocor Ortho Biotech Inc. | Procédés d’humanisation et de maturation d’affinité d’anticorps |
JP2013508287A (ja) | 2009-10-14 | 2013-03-07 | ヤンセン バイオテツク,インコーポレーテツド | 抗体を親和性成熟する方法 |
ES2757857T3 (es) | 2010-09-27 | 2020-04-30 | Janssen Biotech Inc | Anticuerpos de unión a colágeno II humano |
ES2686550T3 (es) * | 2010-10-11 | 2018-10-18 | Biogen International Neuroscience Gmbh | Anticuerpos anti-tau humanos |
CN102457701B (zh) | 2010-11-02 | 2014-03-12 | 华为终端有限公司 | 图像显示处理方法及装置 |
CN103339150A (zh) | 2010-12-03 | 2013-10-02 | 代阿麦迪卡股份有限公司 | 抗缓激肽b2受体(bkb2r)单克隆抗体 |
RU2639537C2 (ru) * | 2011-10-07 | 2017-12-21 | Ац Иммуне С.А. | Фосфоспецифичные антитела, распознающие тау |
CA2859665C (fr) | 2011-12-20 | 2024-05-21 | Janssen Biotech, Inc. | Anticorps anti-phf-tau et leurs utilisations |
CA2952745A1 (fr) * | 2014-06-26 | 2015-12-30 | Janssen Vaccines & Prevention B.V. | Anticorps et fragments de liaison a l'antigene qui se lient specifiquement a la proteine tau associee aux microtubules |
WO2016112078A2 (fr) * | 2015-01-08 | 2016-07-14 | Janssen Biotech, Inc. | Anticorps tau/anti-phf et leurs utilisations |
UA126272C2 (uk) | 2015-06-05 | 2022-09-14 | Дженентек, Інк. | Антитіло проти тау-білка та спосіб його застосування |
WO2017181098A2 (fr) * | 2016-04-15 | 2017-10-19 | Visterra, Inc. | Molécules d'anticorps se liant au virus zika et leurs utilisations |
JOP20180117B1 (ar) * | 2016-07-12 | 2022-03-14 | H Lundbeck As | أجسام مضادة انتقائية لـ tau فائق المعالجة بفوسفوريلات وطرق لاستخدامها |
US11834494B2 (en) * | 2016-07-26 | 2023-12-05 | Washington University | Antibodies to zika virus and methods of use thereof |
-
2019
- 2019-03-04 AU AU2019232631A patent/AU2019232631A1/en active Pending
- 2019-03-04 US US16/291,303 patent/US10633435B2/en active Active
- 2019-03-04 MX MX2020009277A patent/MX2020009277A/es unknown
- 2019-03-04 CA CA3093200A patent/CA3093200A1/fr active Pending
- 2019-03-04 JO JOP/2020/0215A patent/JOP20200215A1/ar unknown
- 2019-03-04 EP EP19765110.2A patent/EP3774888A4/fr active Pending
- 2019-03-04 MA MA052235A patent/MA52235A/fr unknown
- 2019-03-04 CN CN201980030595.6A patent/CN112105639A/zh active Pending
- 2019-03-04 BR BR112020018112-9A patent/BR112020018112A2/pt unknown
- 2019-03-04 TW TW108107082A patent/TW201946654A/zh unknown
- 2019-03-04 WO PCT/IB2019/051748 patent/WO2019171259A1/fr unknown
- 2019-03-04 JP JP2020546389A patent/JP7362636B2/ja active Active
- 2019-03-04 US US16/978,022 patent/US20210002358A1/en active Pending
- 2019-03-04 KR KR1020207028358A patent/KR20200130350A/ko unknown
- 2019-03-04 EA EA202092088A patent/EA202092088A1/ru unknown
- 2019-03-04 SG SG11202008579UA patent/SG11202008579UA/en unknown
-
2020
- 2020-09-01 IL IL277075A patent/IL277075A/en unknown
- 2020-09-02 PH PH12020551373A patent/PH12020551373A1/en unknown
-
2023
- 2023-10-04 JP JP2023172494A patent/JP2024009870A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20190270793A1 (en) | 2019-09-05 |
US10633435B2 (en) | 2020-04-28 |
US20210002358A1 (en) | 2021-01-07 |
MA52235A (fr) | 2021-02-17 |
EP3774888A1 (fr) | 2021-02-17 |
JP2021515556A (ja) | 2021-06-24 |
JP7362636B2 (ja) | 2023-10-17 |
IL277075A (en) | 2020-10-29 |
EA202092088A1 (ru) | 2020-11-13 |
EP3774888A4 (fr) | 2021-12-29 |
TW201946654A (zh) | 2019-12-16 |
MX2020009277A (es) | 2021-01-08 |
JP2024009870A (ja) | 2024-01-23 |
WO2019171259A1 (fr) | 2019-09-12 |
AU2019232631A1 (en) | 2020-09-24 |
CN112105639A (zh) | 2020-12-18 |
JOP20200215A1 (ar) | 2020-09-03 |
BR112020018112A2 (pt) | 2020-12-22 |
CA3093200A1 (fr) | 2019-09-12 |
KR20200130350A (ko) | 2020-11-18 |
PH12020551373A1 (en) | 2021-08-16 |
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