SG11202008177WA - Compstatin analogues and their medical uses - Google Patents
Compstatin analogues and their medical usesInfo
- Publication number
- SG11202008177WA SG11202008177WA SG11202008177WA SG11202008177WA SG11202008177WA SG 11202008177W A SG11202008177W A SG 11202008177WA SG 11202008177W A SG11202008177W A SG 11202008177WA SG 11202008177W A SG11202008177W A SG 11202008177WA SG 11202008177W A SG11202008177W A SG 11202008177WA
- Authority
- SG
- Singapore
- Prior art keywords
- medical uses
- compstatin analogues
- compstatin
- analogues
- medical
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/545—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/472—Complement proteins, e.g. anaphylatoxin, C3a, C5a
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP18158834 | 2018-02-27 | ||
EP18214949 | 2018-12-20 | ||
PCT/EP2019/054685 WO2019166411A1 (en) | 2018-02-27 | 2019-02-26 | Compstatin analogues and their medical uses |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202008177WA true SG11202008177WA (en) | 2020-09-29 |
Family
ID=65516661
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202008177WA SG11202008177WA (en) | 2018-02-27 | 2019-02-26 | Compstatin analogues and their medical uses |
Country Status (17)
Country | Link |
---|---|
US (1) | US11965039B2 (ru) |
EP (1) | EP3759120A1 (ru) |
JP (1) | JP2021515759A (ru) |
KR (1) | KR20200135797A (ru) |
CN (1) | CN112041330A (ru) |
AU (1) | AU2019228639A1 (ru) |
BR (1) | BR112020017385A2 (ru) |
CA (1) | CA3091993A1 (ru) |
CL (1) | CL2020002197A1 (ru) |
CO (1) | CO2020011027A2 (ru) |
IL (1) | IL276877A (ru) |
MX (1) | MX2020008902A (ru) |
PE (1) | PE20201254A1 (ru) |
RU (1) | RU2020128624A (ru) |
SG (1) | SG11202008177WA (ru) |
TW (1) | TW202000686A (ru) |
WO (1) | WO2019166411A1 (ru) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2019247467B2 (en) | 2018-04-06 | 2023-01-19 | The Trustees Of The University Of Pennsylvania | Compstatin analogs with increased solubility and improved pharmacokinetic properties |
KR20220066287A (ko) * | 2019-08-27 | 2022-05-24 | 제트피 에스피브이 3 케이/에스 | 콤프스타틴 유사체 및 이의 의약 용도 |
AU2021309548A1 (en) * | 2020-07-16 | 2023-02-23 | Zp Spv 3 K/S | Inhibitors of complement factor C3 and their medical uses |
MX2023008330A (es) | 2021-01-20 | 2024-01-18 | Viking Therapeutics Inc | Agonistas del receptor dual gip/glp-1 de molécula pequeña, composiciones farmacéuticas y preparación de las mismas para usarse en el tratamiento de trastornos metabólicos y hepáticos. |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000505068A (ja) | 1996-03-13 | 2000-04-25 | トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルベニア | 補体活性化を阻害する新規ペプチド類 |
DE69737479T4 (de) | 1996-08-30 | 2010-05-06 | Novo Nordisk A/S | Glp-1 derivate |
DE69732640T2 (de) | 1996-09-09 | 2006-01-12 | Zealand Pharma A/S | Festphasen-peptidsynthese |
AU4648197A (en) | 1997-09-17 | 1999-04-05 | Burnham Institute, The | Peptides and peptidomimetics for inhibiting complement activation |
US6451987B1 (en) | 1999-03-15 | 2002-09-17 | Novo Nordisk A/S | Ion exchange chromatography of proteins and peptides |
EP1956000B1 (en) | 1999-03-17 | 2016-10-05 | Novo Nordisk A/S | Acylating agents useful for acylating peptides |
AU2003275075A1 (en) | 2002-09-20 | 2004-04-08 | The Trustees Of The University Of Pennsylvania | Compstatin analogs with improved activity |
CN105582523B (zh) | 2005-10-08 | 2022-04-15 | 阿佩利斯制药公司 | 用于眼部病症的补体抑制素和其类似物 |
CA2971349C (en) | 2005-11-28 | 2020-09-08 | The Trustees Of The University Of Pennsylvania | Potent compstatin analogs |
US8442776B2 (en) | 2007-06-08 | 2013-05-14 | The Trustees Of The University Of Pennsylvania | Structure of compstatin-C3 complex and use for rational drug design |
US8946145B2 (en) * | 2009-05-01 | 2015-02-03 | The Trustees Of The University Of Pennsylvania | Modified compstatin with peptide backbone and C-terminal modifications |
CA2813049A1 (en) | 2010-09-23 | 2012-03-29 | The Trustees Of The University Of Pennsylvania | Modified compstatin with improved stability and binding properties |
DK2753636T3 (da) * | 2011-09-07 | 2020-02-03 | Univ Pennsylvania | Compstatinanaloger med forbedret farmakokinetiske egenskaber |
US20160194359A1 (en) | 2012-11-15 | 2016-07-07 | Apellis Pharmaceuticals, Inc. | Cell-reactive, long-acting, or targeted compstatin analogs and related compositions and methods |
WO2014100407A1 (en) | 2012-12-19 | 2014-06-26 | The Regents Of The University Of California | Compstatin analogs |
KR20220066287A (ko) * | 2019-08-27 | 2022-05-24 | 제트피 에스피브이 3 케이/에스 | 콤프스타틴 유사체 및 이의 의약 용도 |
-
2019
- 2019-02-26 BR BR112020017385-1A patent/BR112020017385A2/pt not_active Application Discontinuation
- 2019-02-26 JP JP2020545488A patent/JP2021515759A/ja active Pending
- 2019-02-26 US US16/976,439 patent/US11965039B2/en active Active
- 2019-02-26 AU AU2019228639A patent/AU2019228639A1/en not_active Abandoned
- 2019-02-26 CN CN201980015920.1A patent/CN112041330A/zh active Pending
- 2019-02-26 WO PCT/EP2019/054685 patent/WO2019166411A1/en active Search and Examination
- 2019-02-26 CA CA3091993A patent/CA3091993A1/en active Pending
- 2019-02-26 RU RU2020128624A patent/RU2020128624A/ru unknown
- 2019-02-26 KR KR1020207027897A patent/KR20200135797A/ko unknown
- 2019-02-26 PE PE2020001288A patent/PE20201254A1/es unknown
- 2019-02-26 EP EP19706665.7A patent/EP3759120A1/en active Pending
- 2019-02-26 SG SG11202008177WA patent/SG11202008177WA/en unknown
- 2019-02-26 MX MX2020008902A patent/MX2020008902A/es unknown
- 2019-02-27 TW TW108106905A patent/TW202000686A/zh unknown
-
2020
- 2020-08-23 IL IL276877A patent/IL276877A/en unknown
- 2020-08-26 CL CL2020002197A patent/CL2020002197A1/es unknown
- 2020-09-03 CO CONC2020/0011027A patent/CO2020011027A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
AU2019228639A1 (en) | 2020-09-17 |
WO2019166411A1 (en) | 2019-09-06 |
CA3091993A1 (en) | 2019-09-06 |
RU2020128624A (ru) | 2022-03-28 |
EP3759120A1 (en) | 2021-01-06 |
BR112020017385A2 (pt) | 2020-12-15 |
US20230192770A1 (en) | 2023-06-22 |
IL276877A (en) | 2020-10-29 |
MX2020008902A (es) | 2020-12-03 |
KR20200135797A (ko) | 2020-12-03 |
US11965039B2 (en) | 2024-04-23 |
TW202000686A (zh) | 2020-01-01 |
CN112041330A (zh) | 2020-12-04 |
CL2020002197A1 (es) | 2021-03-05 |
CO2020011027A2 (es) | 2020-12-10 |
PE20201254A1 (es) | 2020-11-16 |
JP2021515759A (ja) | 2021-06-24 |
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