SG11202004795RA - Method for assessing prognosis or risk stratification of liver cancer by using cpg methylation variation in gene - Google Patents
Method for assessing prognosis or risk stratification of liver cancer by using cpg methylation variation in geneInfo
- Publication number
- SG11202004795RA SG11202004795RA SG11202004795RA SG11202004795RA SG11202004795RA SG 11202004795R A SG11202004795R A SG 11202004795RA SG 11202004795R A SG11202004795R A SG 11202004795RA SG 11202004795R A SG11202004795R A SG 11202004795RA SG 11202004795R A SG11202004795R A SG 11202004795RA
- Authority
- SG
- Singapore
- Prior art keywords
- gene
- liver cancer
- risk stratification
- cpg methylation
- assessing prognosis
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20170156527 | 2017-11-22 | ||
| KR1020180137644A KR102052089B1 (ko) | 2017-11-22 | 2018-11-09 | 유전자의 CpG 메틸화 변화를 이용한 간암의 위험도를 평가하는 방법 |
| PCT/KR2018/014207 WO2019103421A2 (ko) | 2017-11-22 | 2018-11-19 | 유전자의 cpg 메틸화 변화를 이용한 간암의 예후 또는 위험도를 평가하는 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202004795RA true SG11202004795RA (en) | 2020-06-29 |
Family
ID=66675922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202004795RA SG11202004795RA (en) | 2017-11-22 | 2018-11-19 | Method for assessing prognosis or risk stratification of liver cancer by using cpg methylation variation in gene |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20210147943A1 (ja) |
| EP (2) | EP3715474A4 (ja) |
| JP (2) | JP7306723B2 (ja) |
| KR (3) | KR102052089B1 (ja) |
| CN (1) | CN111386352B (ja) |
| SG (1) | SG11202004795RA (ja) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102155044B1 (ko) * | 2019-10-08 | 2020-09-11 | 주식회사 레피다인 | 생물학적 시료의 간암 조직 기원 여부를 판별하는 방법 |
| IL280297B (en) * | 2021-01-19 | 2022-09-01 | Nucleix Ltd | Non-invasive cancer detection is based on DNA methylation changes |
| CN113621704B (zh) * | 2021-07-22 | 2023-08-29 | 武汉艾米森生命科技有限公司 | 肝癌的检测和诊断的试剂及试剂盒 |
| CN113981046A (zh) * | 2021-11-05 | 2022-01-28 | 朱运峰 | 一种基于定量pcr技术dna甲基化检测方法及其试剂盒 |
| WO2023082140A1 (zh) * | 2021-11-11 | 2023-05-19 | 华大数极生物科技(深圳)有限公司 | 一种用于诊断肝癌的核酸检测试剂盒 |
| CN118159669A (zh) * | 2021-11-11 | 2024-06-07 | 深圳华大基因股份有限公司 | 一种用于诊断肝癌的核酸及蛋白检测试剂盒 |
| CN113948150B (zh) * | 2021-12-21 | 2022-04-19 | 北京迈基诺基因科技股份有限公司 | Jmml相关基因甲基化水平评估方法、模型及构建方法 |
| CN114369663A (zh) * | 2022-01-18 | 2022-04-19 | 博尔诚（北京）科技有限公司 | 用于肝癌筛查的标志物、探针组合物及其应用 |
| CN116179694A (zh) * | 2022-11-02 | 2023-05-30 | 武汉艾米森生命科技有限公司 | 检测甲基化水平的试剂在制备前列腺癌诊断产品中的应用以及前列腺癌诊断试剂盒 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0700374D0 (en) * | 2007-01-09 | 2007-02-14 | Oncomethylome Sciences S A | NDRG family methylation markers |
| US20100221723A1 (en) * | 2007-08-14 | 2010-09-02 | The Trustees Of Columbia University In The City Of New York | Early detection of cancer by methylated dna in blood |
| KR20100041937A (ko) * | 2008-10-15 | 2010-04-23 | 재단법인서울대학교산학협력재단 | 암 전이 억제 물질의 스크리닝 방법 |
| JP6054750B2 (ja) | 2011-01-28 | 2016-12-27 | 国立研究開発法人国立がん研究センター | 肝細胞癌のリスク評価方法 |
| KR101313756B1 (ko) * | 2012-03-09 | 2013-10-01 | (주)지노믹트리 | 간암 특이적 과메틸화 ＣｐＧ 서열을 이용한 간암의 검출방법 |
| JP6269492B2 (ja) | 2012-09-19 | 2018-01-31 | シスメックス株式会社 | 肝細胞癌に関する情報の取得方法、ならびに肝細胞癌に関する情報を取得するためのマーカーおよびキット |
| JP6369857B2 (ja) | 2013-05-29 | 2018-08-08 | シスメックス株式会社 | 肝細胞癌に関する情報の取得方法、ならびに肝細胞癌に関する情報を取得するためのマーカーおよびキット |
| EP3034624A1 (en) * | 2014-12-18 | 2016-06-22 | Hospital Clínic de Barcelona | Method for the prognosis of hepatocellular carcinoma |
| EP3240912A4 (en) * | 2014-12-31 | 2018-07-25 | Case Western Reserve University | Methods and compositions for detecting esophageal neoplasias and/or metaplasias in the esophagus |
| KR20170071724A (ko) * | 2015-12-16 | 2017-06-26 | 연세대학교 산학협력단 | 간암 발생 특이적 유전자 발현에 관여하는 유전자 구조 내 cpg 섬의 dna 메틸화 변이를 이용한 간암의 예측 또는 진단 방법 |
| CA3008623C (en) * | 2015-12-17 | 2022-10-04 | Illumina, Inc. | Distinguishing methylation levels in complex biological samples |
| WO2017143296A2 (en) * | 2016-02-18 | 2017-08-24 | Gill Inderbir Singh | Prostate cancer aggressiveness biomarkers |
| US11851711B2 (en) * | 2017-09-29 | 2023-12-26 | Arizona Board Of Regents On Behalf Of The University Of Arizona | DNA methylation biomarkers for cancer diagnosing |
-
2018
- 2018-11-09 KR KR1020180137644A patent/KR102052089B1/ko active IP Right Grant
- 2018-11-19 SG SG11202004795RA patent/SG11202004795RA/en unknown
- 2018-11-19 US US16/766,504 patent/US20210147943A1/en not_active Abandoned
- 2018-11-19 CN CN201880075735.7A patent/CN111386352B/zh active Active
- 2018-11-19 JP JP2020546257A patent/JP7306723B2/ja active Active
- 2018-11-19 EP EP18881098.0A patent/EP3715474A4/en active Pending
- 2018-11-19 EP EP22196985.0A patent/EP4180540A1/en active Pending
-
2019
- 2019-06-12 KR KR1020190069625A patent/KR102103887B1/ko active IP Right Grant
- 2019-06-12 KR KR1020190069624A patent/KR102103886B1/ko active IP Right Grant
-
2022
- 2022-04-25 US US17/728,240 patent/US20220259676A1/en active Pending
- 2022-08-16 JP JP2022129672A patent/JP7452894B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3715474A4 (en) | 2022-02-09 |
| JP2021503956A (ja) | 2021-02-15 |
| CN111386352A (zh) | 2020-07-07 |
| US20210147943A1 (en) | 2021-05-20 |
| CN111386352B (zh) | 2024-04-16 |
| KR20190087344A (ko) | 2019-07-24 |
| JP2022164712A (ja) | 2022-10-27 |
| KR102052089B1 (ko) | 2019-12-05 |
| KR20190059215A (ko) | 2019-05-30 |
| KR102103886B1 (ko) | 2020-05-29 |
| EP4180540A1 (en) | 2023-05-17 |
| KR102103887B1 (ko) | 2020-05-29 |
| KR20190088924A (ko) | 2019-07-29 |
| JP7452894B2 (ja) | 2024-03-19 |
| EP3715474A2 (en) | 2020-09-30 |
| US20220259676A1 (en) | 2022-08-18 |
| JP7306723B2 (ja) | 2023-07-11 |
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