SG11202004795RA - Method for assessing prognosis or risk stratification of liver cancer by using cpg methylation variation in gene - Google Patents
Method for assessing prognosis or risk stratification of liver cancer by using cpg methylation variation in geneInfo
- Publication number
- SG11202004795RA SG11202004795RA SG11202004795RA SG11202004795RA SG11202004795RA SG 11202004795R A SG11202004795R A SG 11202004795RA SG 11202004795R A SG11202004795R A SG 11202004795RA SG 11202004795R A SG11202004795R A SG 11202004795RA SG 11202004795R A SG11202004795R A SG 11202004795RA
- Authority
- SG
- Singapore
- Prior art keywords
- gene
- liver cancer
- risk stratification
- cpg methylation
- assessing prognosis
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20170156527 | 2017-11-22 | ||
| KR1020180137644A KR102052089B1 (en) | 2017-11-22 | 2018-11-09 | A method for assessing risk of hepatocellular carcinoma using cpg methylation status of gene |
| PCT/KR2018/014207 WO2019103421A2 (en) | 2017-11-22 | 2018-11-19 | Method for assessing prognosis or risk stratification of liver cancer by using cpg methylation variation in gene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202004795RA true SG11202004795RA (en) | 2020-06-29 |
Family
ID=66675922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202004795RA SG11202004795RA (en) | 2017-11-22 | 2018-11-19 | Method for assessing prognosis or risk stratification of liver cancer by using cpg methylation variation in gene |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20210147943A1 (en) |
| EP (2) | EP3715474A4 (en) |
| JP (2) | JP7306723B2 (en) |
| KR (3) | KR102052089B1 (en) |
| CN (1) | CN111386352B (en) |
| SG (1) | SG11202004795RA (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102155044B1 (en) * | 2019-10-08 | 2020-09-11 | 주식회사 레피다인 | Method for Identifying Whether Biological Sample is Derived from Liver Cancer Tissue |
| IL280297B (en) * | 2021-01-19 | 2022-09-01 | Nucleix Ltd | Non-invasive cancer detection based on dna methylation changes |
| CN113621704B (en) * | 2021-07-22 | 2023-08-29 | 武汉艾米森生命科技有限公司 | Reagent and kit for detecting and diagnosing liver cancer |
| CN113981046A (en) * | 2021-11-05 | 2022-01-28 | 朱运峰 | DNA methylation detection method based on quantitative PCR technology and kit thereof |
| WO2023082140A1 (en) * | 2021-11-11 | 2023-05-19 | 华大数极生物科技(深圳)有限公司 | Nucleic acid detection kit for diagnosing liver cancer |
| CN118159669A (en) * | 2021-11-11 | 2024-06-07 | 深圳华大基因股份有限公司 | Nucleic acid and protein detection kit for diagnosing liver cancer |
| CN113948150B (en) * | 2021-12-21 | 2022-04-19 | 北京迈基诺基因科技股份有限公司 | JMML related gene methylation level evaluation method, model and construction method |
| CN114369663A (en) * | 2022-01-18 | 2022-04-19 | 博尔诚（北京）科技有限公司 | Marker and probe composition for liver cancer screening and application thereof |
| CN116179694A (en) * | 2022-11-02 | 2023-05-30 | 武汉艾米森生命科技有限公司 | Application of reagent for detecting methylation level in preparation of prostate cancer diagnosis product and prostate cancer diagnosis kit |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0700374D0 (en) * | 2007-01-09 | 2007-02-14 | Oncomethylome Sciences S A | NDRG family methylation markers |
| US20100221723A1 (en) * | 2007-08-14 | 2010-09-02 | The Trustees Of Columbia University In The City Of New York | Early detection of cancer by methylated dna in blood |
| KR20100041937A (en) * | 2008-10-15 | 2010-04-23 | 재단법인서울대학교산학협력재단 | Screening method for materials for inhibiting metastasis of cancer |
| JP6054750B2 (en) | 2011-01-28 | 2016-12-27 | 国立研究開発法人国立がん研究センター | Risk assessment method for hepatocellular carcinoma |
| KR101313756B1 (en) * | 2012-03-09 | 2013-10-01 | (주)지노믹트리 | Method for Detecting Liver Cancer Using Liver Cancer Specific Hypermethylated CpG Sequence |
| JP6269492B2 (en) | 2012-09-19 | 2018-01-31 | シスメックス株式会社 | Method for obtaining information on hepatocellular carcinoma, and marker and kit for obtaining information on hepatocellular carcinoma |
| JP6369857B2 (en) | 2013-05-29 | 2018-08-08 | シスメックス株式会社 | Method for obtaining information on hepatocellular carcinoma, and marker and kit for obtaining information on hepatocellular carcinoma |
| EP3034624A1 (en) * | 2014-12-18 | 2016-06-22 | Hospital Clínic de Barcelona | Method for the prognosis of hepatocellular carcinoma |
| EP3240912A4 (en) * | 2014-12-31 | 2018-07-25 | Case Western Reserve University | Methods and compositions for detecting esophageal neoplasias and/or metaplasias in the esophagus |
| KR20170071724A (en) * | 2015-12-16 | 2017-06-26 | 연세대학교 산학협력단 | Method for diagnosing or predicting hepatocellular carcinoma using dna methylation changes of intragenic cpg island involved in hepatocellular carcinoma specific gene expression |
| CA3008623C (en) * | 2015-12-17 | 2022-10-04 | Illumina, Inc. | Distinguishing methylation levels in complex biological samples |
| WO2017143296A2 (en) * | 2016-02-18 | 2017-08-24 | Gill Inderbir Singh | Prostate cancer aggressiveness biomarkers |
| US11851711B2 (en) * | 2017-09-29 | 2023-12-26 | Arizona Board Of Regents On Behalf Of The University Of Arizona | DNA methylation biomarkers for cancer diagnosing |
-
2018
- 2018-11-09 KR KR1020180137644A patent/KR102052089B1/en active IP Right Grant
- 2018-11-19 SG SG11202004795RA patent/SG11202004795RA/en unknown
- 2018-11-19 US US16/766,504 patent/US20210147943A1/en not_active Abandoned
- 2018-11-19 CN CN201880075735.7A patent/CN111386352B/en active Active
- 2018-11-19 JP JP2020546257A patent/JP7306723B2/en active Active
- 2018-11-19 EP EP18881098.0A patent/EP3715474A4/en active Pending
- 2018-11-19 EP EP22196985.0A patent/EP4180540A1/en active Pending
-
2019
- 2019-06-12 KR KR1020190069625A patent/KR102103887B1/en active IP Right Grant
- 2019-06-12 KR KR1020190069624A patent/KR102103886B1/en active IP Right Grant
-
2022
- 2022-04-25 US US17/728,240 patent/US20220259676A1/en active Pending
- 2022-08-16 JP JP2022129672A patent/JP7452894B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3715474A4 (en) | 2022-02-09 |
| JP2021503956A (en) | 2021-02-15 |
| CN111386352A (en) | 2020-07-07 |
| US20210147943A1 (en) | 2021-05-20 |
| CN111386352B (en) | 2024-04-16 |
| KR20190087344A (en) | 2019-07-24 |
| JP2022164712A (en) | 2022-10-27 |
| KR102052089B1 (en) | 2019-12-05 |
| KR20190059215A (en) | 2019-05-30 |
| KR102103886B1 (en) | 2020-05-29 |
| EP4180540A1 (en) | 2023-05-17 |
| KR102103887B1 (en) | 2020-05-29 |
| KR20190088924A (en) | 2019-07-29 |
| JP7452894B2 (en) | 2024-03-19 |
| EP3715474A2 (en) | 2020-09-30 |
| US20220259676A1 (en) | 2022-08-18 |
| JP7306723B2 (en) | 2023-07-11 |
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