SG11202004786QA - Dried implant composition and injectable aqueous implant formulation - Google Patents

Dried implant composition and injectable aqueous implant formulation

Info

Publication number
SG11202004786QA
SG11202004786QA SG11202004786QA SG11202004786QA SG11202004786QA SG 11202004786Q A SG11202004786Q A SG 11202004786QA SG 11202004786Q A SG11202004786Q A SG 11202004786QA SG 11202004786Q A SG11202004786Q A SG 11202004786QA SG 11202004786Q A SG11202004786Q A SG 11202004786QA
Authority
SG
Singapore
Prior art keywords
implant
injectable aqueous
dried
formulation
composition
Prior art date
Application number
SG11202004786QA
Other languages
English (en)
Inventor
Daniel Suppiger
Paul Buxton
Nino Kurz
Original Assignee
Geistlich Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geistlich Pharma Ag filed Critical Geistlich Pharma Ag
Publication of SG11202004786QA publication Critical patent/SG11202004786QA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0003—Not used, see subgroups
    • A61C8/0004—Consolidating natural teeth
    • A61C8/0006—Periodontal tissue or bone regeneration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0035—Gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0041—X-rays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/362—Skin, e.g. dermal papillae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3625—Vascular tissue, e.g. heart valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20—Targets to be treated
    • A61L2202/21—Pharmaceuticals, e.g. medicaments, artificial body parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Inorganic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Dentistry (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Surgery (AREA)
  • Cardiology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Preparations (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Dental Prosthetics (AREA)
SG11202004786QA 2017-12-14 2018-12-14 Dried implant composition and injectable aqueous implant formulation SG11202004786QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17207341 2017-12-14
PCT/EP2018/085018 WO2019115792A1 (en) 2017-12-14 2018-12-14 Dried implant composition and injectable aqueous implant formulation

Publications (1)

Publication Number Publication Date
SG11202004786QA true SG11202004786QA (en) 2020-07-29

Family

ID=60781545

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202004786QA SG11202004786QA (en) 2017-12-14 2018-12-14 Dried implant composition and injectable aqueous implant formulation

Country Status (14)

Country Link
US (2) US10695461B2 (ja)
EP (2) EP3713615B1 (ja)
JP (2) JP2021506376A (ja)
KR (2) KR102274968B1 (ja)
CN (2) CN113018513B (ja)
AU (1) AU2018383017B2 (ja)
BR (1) BR112020011536B1 (ja)
CA (1) CA3083685C (ja)
ES (2) ES2900259T3 (ja)
IL (1) IL275206B2 (ja)
MX (1) MX2020006214A (ja)
SG (1) SG11202004786QA (ja)
TW (1) TWI806941B (ja)
WO (2) WO2019115792A1 (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2020005846A (es) 2017-12-14 2020-09-07 Geistlich Pharma Ag Material de sustitucion osea.
CN114761048B (zh) 2019-06-14 2023-05-02 盖斯特里希医药公司 骨替代材料的胶原基质或颗粒共混物
ES2939083T3 (es) 2019-06-14 2023-04-18 Geistlich Pharma Ag Formulación acuosa de implante inyectable que contiene ácido ascórbico
KR20220110203A (ko) * 2019-12-04 2022-08-05 데이텀 덴탈 엘티디. 비수술적 치주질환 치료를 위한 콜라겐-하이드록시아파타이트 장치
CN115252898B (zh) * 2022-08-19 2023-08-18 江苏西宏生物医药有限公司 一种长效微粒ⅰ型与ⅴ型胶原蛋白复合植入剂

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4865602A (en) 1986-11-06 1989-09-12 Collagen Corporation Gamma irradiation of collagen/mineral mixtures
GB8813033D0 (en) 1988-06-02 1988-07-06 Geistlich Soehne Ag Chemical compound
ATE208217T1 (de) * 1992-02-28 2001-11-15 Cohesion Tech Inc Injektierbare, keramische verbindungen sowie verfahren zur deren herstellung und anwendung
GB9400163D0 (en) 1994-01-06 1994-03-02 Geistlich Soehne Ag Membrane
US20020025921A1 (en) * 1999-07-26 2002-02-28 Petito George D. Composition and method for growing, protecting, and healing tissues and cells
US20030026770A1 (en) * 2001-07-25 2003-02-06 Szymaitis Dennis W. Periodontal regeneration composition and method of using same
US7582309B2 (en) * 2002-11-15 2009-09-01 Etex Corporation Cohesive demineralized bone compositions
US20070026030A1 (en) * 2005-07-27 2007-02-01 Berkeley Advanced Biomaterials, Inc. Method of preparing rheological materials for bone and cartilage repair
CN101564553B (zh) * 2009-06-05 2012-08-29 陕西瑞盛生物科技有限公司 人源化活性煅烧骨的制备方法
WO2011126294A2 (ko) * 2010-04-06 2011-10-13 동국대학교 산학협력단 콜라겐 하이드로겔 제조용 멀티 시린지
US9107983B2 (en) 2010-10-27 2015-08-18 Warsaw Orthopedic, Inc. Osteoconductive matrices comprising statins
EP2640429B1 (en) * 2010-11-15 2016-12-21 Zimmer Orthobiologics, Inc. Bone void fillers
EP2654816B1 (en) 2010-12-22 2015-02-11 Geistlich Pharma AG Bone substitute material
DE102011008604A1 (de) 2011-01-14 2012-07-19 Tutogen Medical Gmbh Herstellung eines Transplantats aus tierischer Dermis mit Natriumsulfidlösung
US9474718B2 (en) * 2013-05-15 2016-10-25 Europesearch S.R.L. Collagen powder, composition and use
EP2826495A1 (en) * 2013-07-19 2015-01-21 Geistlich Pharma AG Biomimetic collagen-hydroxyapatite composite material
CN104274861A (zh) * 2014-07-25 2015-01-14 上海国睿生命科技有限公司 一种牙髓牙本质再生的可注射组织工程构建方法
EP3175869A1 (en) * 2015-12-04 2017-06-07 Geistlich Pharma AG Resorbable crosslinked formstable membrane
CN105311681B (zh) * 2015-12-07 2018-12-25 杭州华迈医疗器械有限公司 一种可注射的骨修复用复合材料及其制备方法
CN105816919B (zh) * 2016-05-23 2019-06-11 烟台正海生物科技股份有限公司 一种含有天然纳米羟基磷灰石的复合材料及其制备方法

Also Published As

Publication number Publication date
US20200345893A1 (en) 2020-11-05
US10695461B2 (en) 2020-06-30
JP2021506376A (ja) 2021-02-22
ES2897211T3 (es) 2022-02-28
EP3713615A1 (en) 2020-09-30
MX2020006214A (es) 2020-08-31
AU2018383017A1 (en) 2020-06-11
JP2023022260A (ja) 2023-02-14
KR102274968B1 (ko) 2021-07-09
CN113018513A (zh) 2021-06-25
CA3083685A1 (en) 2019-06-20
BR112020011536A2 (pt) 2020-11-17
WO2019115792A1 (en) 2019-06-20
CA3083685C (en) 2022-08-30
BR112020011536B1 (pt) 2021-12-21
WO2019115795A1 (en) 2019-06-20
KR20210086725A (ko) 2021-07-08
KR102330140B1 (ko) 2021-11-23
KR20200091459A (ko) 2020-07-30
EP3713614A1 (en) 2020-09-30
EP3713614B1 (en) 2021-09-29
TW201927277A (zh) 2019-07-16
CN113018513B (zh) 2022-05-13
AU2018383017B2 (en) 2024-04-11
EP3713615B1 (en) 2021-10-27
CN111511415A (zh) 2020-08-07
US11633519B2 (en) 2023-04-25
RU2020119258A (ru) 2022-01-14
US20190209735A1 (en) 2019-07-11
IL275206B (en) 2022-12-01
IL275206A (en) 2020-07-30
ES2900259T3 (es) 2022-03-16
IL275206B2 (en) 2023-04-01
RU2020119258A3 (ja) 2022-04-29
TWI806941B (zh) 2023-07-01
CN111511415B (zh) 2021-04-20

Similar Documents

Publication Publication Date Title
IL275206A (en) Dry implant composition and aqueous injection formulation of the implant
IL271275A (en) Preparations containing coronas and their uses
IL273571A (en) Azterion derivatives and their uses
IL281938A (en) Stable compositions of semaglutide and uses thereof
GB201711635D0 (en) Immunogenic composition
GB202002129D0 (en) stable freshening compositions and products comprising the same
IL290166A (en) Collagen preparations 7 and its use
GB2574954B (en) Tissue scaffold and scaffold composition
SG11202002224XA (en) Composition and uses thereof
PL3307275T3 (pl) Postacie użytkowe antybiotyków do wstrzykiwania i ich zastosowanie
EP3568203C0 (en) COMPOUNDS AND COMPOSITIONS
SI3381457T1 (sl) Fiziološka aktivna sestava, ki vsebuje N-acetilglukozamin za zdravljenje bolečin v hrbtu
IL273967A (en) Aqueous preparations containing bilastin and methotrexate
GB201707700D0 (en) Dried composition
SG11202004167XA (en) Immunogenic compositions and uses therefor
ZA202001677B (en) Composition comprising a structured aqueous phase and sericin
GB2607546B (en) Functional composition and uses thereof
PT3694557T (pt) Excipientes modificadores de libertação à base de amido e composições farmacêuticas derivadas dos mesmos
IL268137A (en) Composition comprising immediate release and extended release capecitabine
GB201812952D0 (en) Compositions and uses thereof
GB201714849D0 (en) Composition and components
PT3532111T (pt) Composição bioativa óssea e suas utilizações
GB201713920D0 (en) Pharmaceutical compositions and uses thereof
IL252660B (en) Compounds characterized by an inverse freezing property and their uses
GB201715730D0 (en) Chitin-chitosanhydrogel compositions and their uses