SG11202003273PA - Anti-cd3 antibody and pharmaceutical composition for cancer treatment comprising same - Google Patents

Anti-cd3 antibody and pharmaceutical composition for cancer treatment comprising same

Info

Publication number
SG11202003273PA
SG11202003273PA SG11202003273PA SG11202003273PA SG11202003273PA SG 11202003273P A SG11202003273P A SG 11202003273PA SG 11202003273P A SG11202003273P A SG 11202003273PA SG 11202003273P A SG11202003273P A SG 11202003273PA SG 11202003273P A SG11202003273P A SG 11202003273PA
Authority
SG
Singapore
Prior art keywords
antibody
same
pharmaceutical composition
cancer treatment
cancer
Prior art date
Application number
SG11202003273PA
Other languages
English (en)
Inventor
Ki Su Kim
Jun Hong Jeong
Ae Rin Yoon
Eun Jung Song
Hye Ji Choi
Ok Jae Lim
Yun Jung Lee
Hyung Kwon Lim
Jong Wha Won
Original Assignee
Green Cross Corp
Mogam Inst Biomedical Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp, Mogam Inst Biomedical Res filed Critical Green Cross Corp
Publication of SG11202003273PA publication Critical patent/SG11202003273PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11202003273PA 2017-10-20 2018-10-22 Anti-cd3 antibody and pharmaceutical composition for cancer treatment comprising same SG11202003273PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020170136564A KR101973060B1 (ko) 2017-10-20 2017-10-20 항-cd3 항체 및 이를 포함하는 암 치료용 약학적 조성물
PCT/KR2018/012492 WO2019078697A2 (fr) 2017-10-20 2018-10-22 Anticorps anti-cd3 et composition pharmaceutique destinée au traitement du cancer, contenant ledit anticorps

Publications (1)

Publication Number Publication Date
SG11202003273PA true SG11202003273PA (en) 2020-05-28

Family

ID=66173409

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202003273PA SG11202003273PA (en) 2017-10-20 2018-10-22 Anti-cd3 antibody and pharmaceutical composition for cancer treatment comprising same

Country Status (13)

Country Link
US (2) US11498965B2 (fr)
EP (1) EP3699192A4 (fr)
JP (1) JP7024072B2 (fr)
KR (1) KR101973060B1 (fr)
CN (1) CN111315779B (fr)
AU (1) AU2018353787B2 (fr)
BR (1) BR112020007770A2 (fr)
CA (1) CA3077007C (fr)
EA (1) EA202090944A1 (fr)
IL (1) IL274007A (fr)
MX (1) MX2020003947A (fr)
SG (1) SG11202003273PA (fr)
WO (1) WO2019078697A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020236797A1 (fr) * 2019-05-21 2020-11-26 Novartis Ag Domaines de cd58 variants et leurs utilisations
CA3196933A1 (fr) * 2020-09-29 2022-04-07 Innovent Biologics (Suzhou) Co., Ltd. Anticorps anti-cd3 et ses utilisations

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003243138A1 (en) * 2002-03-26 2003-10-13 Trubion Pharmaceuticals, Inc. Activation of tumor-reactive lymphocytes via antibodies or genes recognizing cd3 or 4-1bb
AU2006301492B2 (en) 2005-10-11 2011-06-09 Amgen Research (Munich) Gmbh Compositions comprising cross-species-specific antibodies and uses thereof
CN103842383B (zh) * 2011-05-16 2017-11-03 健能隆医药技术(上海)有限公司 多特异性fab融合蛋白及其使用方法
ME03440B (fr) * 2011-05-21 2020-01-20 Macrogenics Inc Molécules de liaison des cd3 capables de se lier aux cd3 humaines et non humaines
JOP20200236A1 (ar) * 2012-09-21 2017-06-16 Regeneron Pharma الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
EP3693385A1 (fr) * 2013-07-05 2020-08-12 Genmab A/S Anticorps anti-cd3 humanisés ou chimères
EP2839842A1 (fr) * 2013-08-23 2015-02-25 MacroGenics, Inc. Bianticorps monovalents bi-spécifiques capables de se lier aux CD123 et CD3 et leurs utilisations
ES2811923T3 (es) * 2013-12-17 2021-03-15 Genentech Inc Anticuerpos anti-CD3 y métodos de uso
JP2017520575A (ja) * 2014-07-01 2017-07-27 ファイザー・インク 二重特異的ヘテロ二量体ダイアボディおよびその使用
EP2982693A1 (fr) * 2014-08-07 2016-02-10 Affimed Therapeutics AG Domaine de liaison CD3
CN109069635B (zh) 2016-02-04 2023-09-26 斯克利普斯研究所 人源化抗cd3抗体、偶联物及其用途
KR102329635B1 (ko) * 2017-04-24 2021-11-22 재단법인 목암생명과학연구소 Her3 및 cd3에 결합하는 이중특이적 항체

Also Published As

Publication number Publication date
AU2018353787B2 (en) 2022-02-24
KR101973060B1 (ko) 2019-04-26
EP3699192A4 (fr) 2021-10-20
US20200317779A1 (en) 2020-10-08
WO2019078697A2 (fr) 2019-04-25
JP7024072B2 (ja) 2022-02-22
WO2019078697A8 (fr) 2020-04-09
EA202090944A1 (ru) 2020-07-16
US11498965B2 (en) 2022-11-15
CA3077007A1 (fr) 2019-04-25
MX2020003947A (es) 2020-08-03
CN111315779A (zh) 2020-06-19
WO2019078697A3 (fr) 2019-07-04
BR112020007770A2 (pt) 2020-10-20
JP2021501571A (ja) 2021-01-21
CA3077007C (fr) 2023-04-18
US20230192851A1 (en) 2023-06-22
AU2018353787A1 (en) 2020-05-21
CN111315779B (zh) 2024-06-21
IL274007A (en) 2020-05-31
EP3699192A2 (fr) 2020-08-26

Similar Documents

Publication Publication Date Title
HUE054316T2 (hu) Gyógyászati készítmény rák kezelésére
HK1257056A1 (zh) 抗dll3抗體藥物綴合物以及使用方法
EP3524268A4 (fr) Utilisation d'une combinaison d'un anticorps anti-pd-1 et d'un inhibiteur de vegfr dans la préparation d'un médicament pour le traitement de cancers
HK1247848A1 (zh) 抗pd-1和抗m-csf抗體在治療癌症中的聯合應用
IL311136A (en) Anti-CD3 antibody for use in the treatment or prevention of cancer and molecules containing the antibody
IL260474B (en) Antibodies specific to cadherin-17 and cytotoxic cells for cancer treatment
IL266486A (en) Pharmaceutical preparations and methods for cancer treatment
EP3502142A4 (fr) Anticorps bispécifique et conjugué d'anticorps pour thérapie tumorale et leurs utilisations
IL274008A (en) Anti-MSLN antibody and a pharmaceutical preparation containing it for the treatment of cancer
IL272669A (en) Combination therapy with a combination of anti-CSF1R and anti-PD-1 antibodies for pancreatic cancer
EP3708173C0 (fr) Composition pharmaceutique comprenant du mirna-3140 pour le traitement du cancer
IL275525A (en) A pharmaceutical preparation for the treatment of cancer
ZA201802618B (en) Anti-cd43 antibody and use thereof for cancer treatment
IL274007A (en) Anti-CD3 antibody and a pharmaceutical preparation containing it for the treatment of cancer
PT3290051T (pt) Composição farmacêutica para o tratamento e/ou prevenção de cancro
EP3563856A4 (fr) Composition pharmaceutique destinée au traitement du cancer, et utilisation correspondante
EP3647325A4 (fr) Composition pharmaceutique comprenant un anticorps pcsk-9 et son utilisation
EP3406626A4 (fr) Peptide pour traitement du cancer, et composition pharmaceutique contenant celui-ci
IL249860A0 (en) Pharmaceutical preparations, methods for their preparation and their use for the treatment of cancer
EP3372233A4 (fr) Composition pharmaceutique pour le traitement et/ou la prévention du cancer
EP3441465A4 (fr) Composition médicamenteuse pour traitement du cancer mettant en oeuvre un anticorps anti-mct5
HK1254918A1 (zh) Etar抗體,其藥物組合物及其應用
GB201718925D0 (en) Pharmaceutical composition suitable for gastric cancer treatment and/or prevention
EP3498284A4 (fr) Composition pharmaceutique pour le traitement et/ou la prévention du cancer
GB201713936D0 (en) Pharmaceutical combinations for the treatment of cancer