SG11202003273PA - Anti-cd3 antibody and pharmaceutical composition for cancer treatment comprising same - Google Patents

Anti-cd3 antibody and pharmaceutical composition for cancer treatment comprising same

Info

Publication number
SG11202003273PA
SG11202003273PA SG11202003273PA SG11202003273PA SG11202003273PA SG 11202003273P A SG11202003273P A SG 11202003273PA SG 11202003273P A SG11202003273P A SG 11202003273PA SG 11202003273P A SG11202003273P A SG 11202003273PA SG 11202003273P A SG11202003273P A SG 11202003273PA
Authority
SG
Singapore
Prior art keywords
antibody
same
pharmaceutical composition
cancer treatment
cancer
Prior art date
Application number
SG11202003273PA
Inventor
Ki Su Kim
Jun Hong Jeong
Ae Rin Yoon
Eun Jung Song
Hye Ji Choi
Ok Jae Lim
Yun Jung Lee
Hyung Kwon Lim
Jong Wha Won
Original Assignee
Green Cross Corp
Mogam Inst Biomedical Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp, Mogam Inst Biomedical Res filed Critical Green Cross Corp
Publication of SG11202003273PA publication Critical patent/SG11202003273PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11202003273PA 2017-10-20 2018-10-22 Anti-cd3 antibody and pharmaceutical composition for cancer treatment comprising same SG11202003273PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020170136564A KR101973060B1 (en) 2017-10-20 2017-10-20 Antibody against cd3 and pharmaceutical composition for treating cancer comprising the same
PCT/KR2018/012492 WO2019078697A2 (en) 2017-10-20 2018-10-22 Anti-cd3 antibody and pharmaceutical composition for cancer treatment comprising same

Publications (1)

Publication Number Publication Date
SG11202003273PA true SG11202003273PA (en) 2020-05-28

Family

ID=66173409

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202003273PA SG11202003273PA (en) 2017-10-20 2018-10-22 Anti-cd3 antibody and pharmaceutical composition for cancer treatment comprising same

Country Status (13)

Country Link
US (2) US11498965B2 (en)
EP (1) EP3699192A4 (en)
JP (1) JP7024072B2 (en)
KR (1) KR101973060B1 (en)
CN (1) CN111315779B (en)
AU (1) AU2018353787B2 (en)
BR (1) BR112020007770A2 (en)
CA (1) CA3077007C (en)
EA (1) EA202090944A1 (en)
IL (1) IL274007A (en)
MX (1) MX2020003947A (en)
SG (1) SG11202003273PA (en)
WO (1) WO2019078697A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020236797A1 (en) * 2019-05-21 2020-11-26 Novartis Ag Variant cd58 domains and uses thereof
TW202216784A (en) * 2020-09-29 2022-05-01 大陸商信達生物製藥(蘇州)有限公司 Anti-cd3 antibody and the use thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003243138A1 (en) 2002-03-26 2003-10-13 Trubion Pharmaceuticals, Inc. Activation of tumor-reactive lymphocytes via antibodies or genes recognizing cd3 or 4-1bb
EP1940881B1 (en) * 2005-10-11 2016-11-30 Amgen Research (Munich) GmbH Compositions comprising cross-species-specific antibodies and uses thereof
WO2012158818A2 (en) * 2011-05-16 2012-11-22 Fabion Pharmaceuticals, Inc. Multi-specific fab fusion proteins and methods of use
SG10201509588TA (en) * 2011-05-21 2015-12-30 Macrogenics Inc CD3-Binding Molecules Capable Of Binding To Human And Non-Human CD3
JOP20200236A1 (en) 2012-09-21 2017-06-16 Regeneron Pharma Anti-cd3 antibodies, bispecific antigen-binding molecules that bind cd3 and cd20, and uses thereof
KR102363220B1 (en) 2013-07-05 2022-02-15 젠맵 에이/에스 Humanized or chimeric cd3 antibodies
EP2839842A1 (en) * 2013-08-23 2015-02-25 MacroGenics, Inc. Bi-specific monovalent diabodies that are capable of binding CD123 and CD3 and uses thereof
WO2015095392A1 (en) * 2013-12-17 2015-06-25 Genentech, Inc. Anti-cd3 antibodies and methods of use
EP3164417A1 (en) 2014-07-01 2017-05-10 Pfizer Inc. Bispecific heterodimeric diabodies and uses thereof
EP2982693A1 (en) * 2014-08-07 2016-02-10 Affimed Therapeutics AG CD3 binding domain
JP6951826B2 (en) * 2016-02-04 2021-10-20 ザ スクリプス リサーチ インスティテュート Humanized anti-CD3 antibody, its complex, and its use
KR102329635B1 (en) 2017-04-24 2021-11-22 재단법인 목암생명과학연구소 Bispecific antibodies that bind HER3 and CD3

Also Published As

Publication number Publication date
AU2018353787B2 (en) 2022-02-24
KR101973060B1 (en) 2019-04-26
BR112020007770A2 (en) 2020-10-20
CA3077007A1 (en) 2019-04-25
MX2020003947A (en) 2020-08-03
CA3077007C (en) 2023-04-18
CN111315779B (en) 2024-06-21
US20200317779A1 (en) 2020-10-08
EA202090944A1 (en) 2020-07-16
IL274007A (en) 2020-05-31
WO2019078697A2 (en) 2019-04-25
US11498965B2 (en) 2022-11-15
EP3699192A2 (en) 2020-08-26
CN111315779A (en) 2020-06-19
AU2018353787A1 (en) 2020-05-21
US20230192851A1 (en) 2023-06-22
WO2019078697A8 (en) 2020-04-09
WO2019078697A3 (en) 2019-07-04
JP7024072B2 (en) 2022-02-22
EP3699192A4 (en) 2021-10-20
JP2021501571A (en) 2021-01-21

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