SG11202002975YA - Treatment of focal segmental glomerulosclerosis with ccr2 antagonists - Google Patents

Treatment of focal segmental glomerulosclerosis with ccr2 antagonists

Info

Publication number
SG11202002975YA
SG11202002975YA SG11202002975YA SG11202002975YA SG11202002975YA SG 11202002975Y A SG11202002975Y A SG 11202002975YA SG 11202002975Y A SG11202002975Y A SG 11202002975YA SG 11202002975Y A SG11202002975Y A SG 11202002975YA SG 11202002975Y A SG11202002975Y A SG 11202002975YA
Authority
SG
Singapore
Prior art keywords
treatment
focal segmental
segmental glomerulosclerosis
ccr2 antagonists
ccr2
Prior art date
Application number
SG11202002975YA
Other languages
English (en)
Inventor
Zhenhua Miao
Thomas Schall
Rajinder Singh
Original Assignee
Chemocentryx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemocentryx Inc filed Critical Chemocentryx Inc
Publication of SG11202002975YA publication Critical patent/SG11202002975YA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Electrotherapy Devices (AREA)
SG11202002975YA 2017-10-11 2018-10-10 Treatment of focal segmental glomerulosclerosis with ccr2 antagonists SG11202002975YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762570778P 2017-10-11 2017-10-11
PCT/US2018/055244 WO2019075086A1 (en) 2017-10-11 2018-10-10 TREATMENT OF FOCAL SEGMENTAL GLOBEROSCLEROSIS WITH CCR2 ANTAGONISTS

Publications (1)

Publication Number Publication Date
SG11202002975YA true SG11202002975YA (en) 2020-04-29

Family

ID=66101688

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202002975YA SG11202002975YA (en) 2017-10-11 2018-10-10 Treatment of focal segmental glomerulosclerosis with ccr2 antagonists

Country Status (17)

Country Link
US (3) US10758540B2 (es)
EP (1) EP3694504A4 (es)
JP (1) JP2020536919A (es)
KR (1) KR20200070299A (es)
CN (1) CN111417389A (es)
AR (1) AR113440A1 (es)
AU (1) AU2018347361A1 (es)
BR (1) BR112020007183A2 (es)
CA (1) CA3078809A1 (es)
CL (1) CL2020000974A1 (es)
IL (1) IL273717A (es)
MX (1) MX2020003502A (es)
RU (1) RU2020113612A (es)
SG (1) SG11202002975YA (es)
TW (1) TW201922246A (es)
WO (1) WO2019075086A1 (es)
ZA (1) ZA202002049B (es)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112019010375A2 (pt) * 2016-11-23 2019-08-27 Chemocentryx Inc método de tratamento de glomeruloesclerose segmental focal
SG11202002975YA (en) * 2017-10-11 2020-04-29 Chemocentryx Inc Treatment of focal segmental glomerulosclerosis with ccr2 antagonists
HUE066335T2 (hu) 2018-10-05 2024-07-28 Annapurna Bio Inc Vegyületek és készítmények APJ receptor aktivitáshoz kapcsolódó állapotok kezelésére
TW202130350A (zh) 2019-12-17 2021-08-16 美商奇努克治療美國公司 用阿曲生坦（ＡＴＲＡＳＥＮＴＡＮ）治療ＩｇＡ腎病的方法
EP4146639A1 (en) 2020-05-06 2023-03-15 Ajax Therapeutics, Inc. 6-heteroaryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors
EP4267574A1 (en) 2020-12-23 2023-11-01 Ajax Therapeutics, Inc. 6-heteroaryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors
WO2022198264A1 (en) * 2021-03-23 2022-09-29 Dimerix Bioscience Pty Ltd Treatment of inflammatory diseases
TW202334139A (zh) 2021-11-09 2023-09-01 美商雅捷可斯治療公司 作為ｊａｋ２抑制劑之６－雜芳氧基苯并咪唑及氮雜苯并咪唑
TW202423432A (zh) * 2022-11-11 2024-06-16 日商亞克醫藥股份有限公司 化合物、內皮素a受體拮抗劑、血管收縮素ii第一型受體拮抗劑及醫藥組合物

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Also Published As

Publication number Publication date
CN111417389A (zh) 2020-07-14
BR112020007183A2 (pt) 2020-09-24
KR20200070299A (ko) 2020-06-17
JP2020536919A (ja) 2020-12-17
US20190134042A1 (en) 2019-05-09
CL2020000974A1 (es) 2020-08-14
EP3694504A4 (en) 2021-07-14
MX2020003502A (es) 2021-09-30
RU2020113612A3 (es) 2022-04-29
AR113440A1 (es) 2020-05-06
US20210000834A1 (en) 2021-01-07
AU2018347361A1 (en) 2020-04-30
IL273717A (en) 2020-05-31
ZA202002049B (en) 2021-10-27
US20220296601A1 (en) 2022-09-22
EP3694504A1 (en) 2020-08-19
US11382915B2 (en) 2022-07-12
RU2020113612A (ru) 2021-11-12
CA3078809A1 (en) 2019-04-18
US10758540B2 (en) 2020-09-01
WO2019075086A1 (en) 2019-04-18
TW201922246A (zh) 2019-06-16

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