SG11202002281YA - Nasal hepatitis b vaccine composition and method for producing same - Google Patents

Nasal hepatitis b vaccine composition and method for producing same

Info

Publication number
SG11202002281YA
SG11202002281YA SG11202002281YA SG11202002281YA SG11202002281YA SG 11202002281Y A SG11202002281Y A SG 11202002281YA SG 11202002281Y A SG11202002281Y A SG 11202002281YA SG 11202002281Y A SG11202002281Y A SG 11202002281YA SG 11202002281Y A SG11202002281Y A SG 11202002281YA
Authority
SG
Singapore
Prior art keywords
vaccine composition
producing same
hepatitis
nasal
nasal hepatitis
Prior art date
Application number
SG11202002281YA
Other languages
English (en)
Inventor
Taizou Kamishita
Takashi Miyazaki
Michinori Kohara
Takahiro Sanada
Yoichi Hiasa
Osamu Yoshida
Kyoko Kohara
Hideki Hasegawa
Original Assignee
Toko Yakuhin Kogyo Co Ltd
Tokyo Metropolitan Inst Medical Science
Japan As Represented By Director General Of Nat Institute Of Infectious Diseases
Univ Kagoshima
Univ Nat Corp Ehime Univ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toko Yakuhin Kogyo Co Ltd, Tokyo Metropolitan Inst Medical Science, Japan As Represented By Director General Of Nat Institute Of Infectious Diseases, Univ Kagoshima, Univ Nat Corp Ehime Univ filed Critical Toko Yakuhin Kogyo Co Ltd
Publication of SG11202002281YA publication Critical patent/SG11202002281YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • A61K39/292Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • A61K9/124Aerosols; Foams characterised by the propellant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Otolaryngology (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SG11202002281YA 2017-10-05 2018-10-04 Nasal hepatitis b vaccine composition and method for producing same SG11202002281YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017195262 2017-10-05
PCT/JP2018/037172 WO2019070019A1 (ja) 2017-10-05 2018-10-04 経鼻b型肝炎ワクチン組成物およびその製造方法

Publications (1)

Publication Number Publication Date
SG11202002281YA true SG11202002281YA (en) 2020-04-29

Family

ID=65994315

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202002281YA SG11202002281YA (en) 2017-10-05 2018-10-04 Nasal hepatitis b vaccine composition and method for producing same

Country Status (14)

Country Link
US (1) US11491219B2 (ko)
EP (1) EP3693006A4 (ko)
JP (2) JPWO2019070019A1 (ko)
KR (1) KR102673991B1 (ko)
CN (1) CN111344005A (ko)
AU (1) AU2018345493A1 (ko)
BR (1) BR112020005695A2 (ko)
CA (1) CA3075423A1 (ko)
IL (1) IL273168B1 (ko)
MX (1) MX2020003753A (ko)
PH (1) PH12020550211A1 (ko)
SG (1) SG11202002281YA (ko)
TW (1) TWI811248B (ko)
WO (1) WO2019070019A1 (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024048570A1 (ja) * 2022-08-30 2024-03-07 国立大学法人愛媛大学 経鼻投与用b型肝炎ワクチン組成物および該ワクチン組成物の経鼻投与システム

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5158761A (en) * 1989-04-05 1992-10-27 Toko Yakuhin Kogyo Kabushiki Kaisha Spray gel base and spray gel preparation using thereof
CN1171636C (zh) * 2001-06-06 2004-10-20 中国人民解放军第二军医大学 一种乙型肝炎dna疫苗
CU23031A1 (es) * 2002-01-24 2005-02-23 Ct Ingenieria Genetica Biotech Antigeno de superficie del virus de la hepatitis b como inmunopotenciador mucosal, formulaciones resultantes
CU23405A1 (es) 2003-10-20 2009-08-04 Ct Ingenieria Genetica Biotech Composiciones farmacéuticas para uso terapéutico
SI2011467T1 (sl) 2006-04-21 2021-01-29 Toko Yakuhin Kogyo Kabushiki Kaisha Posoda za tekočino in brezzračni sistem za razdeljevanje tekočine
DK2014305T3 (en) 2006-04-21 2017-10-16 Toko Yakuhin Kogyo Kk SPRAYABLE GEL-SHAPED SKIN / MOSPHONE ADHESIVE AND ADMINISTRATIVE SYSTEM FOR USING THE PREPARATION
AU2013367751B2 (en) * 2012-12-28 2018-02-08 Japan As Represented By Director General Of National Institute Of Infectious Diseases Nasal influenza vaccine composition
JP6322844B2 (ja) 2014-06-25 2018-05-16 東興薬品工業株式会社 医療用シリンジに用いられる点鼻用噴霧ノズル

Also Published As

Publication number Publication date
TWI811248B (zh) 2023-08-11
KR20200071742A (ko) 2020-06-19
JPWO2019070019A1 (ja) 2020-10-22
TW201922226A (zh) 2019-06-16
US11491219B2 (en) 2022-11-08
IL273168B1 (en) 2024-03-01
BR112020005695A2 (pt) 2020-10-06
US20200261568A1 (en) 2020-08-20
WO2019070019A1 (ja) 2019-04-11
EP3693006A4 (en) 2021-07-07
MX2020003753A (es) 2020-11-09
JP2023012539A (ja) 2023-01-25
PH12020550211A1 (en) 2021-02-15
RU2020115051A3 (ko) 2021-11-18
CN111344005A (zh) 2020-06-26
IL273168A (en) 2020-04-30
EP3693006A1 (en) 2020-08-12
AU2018345493A1 (en) 2020-04-02
RU2020115051A (ru) 2021-11-08
KR102673991B1 (ko) 2024-06-10
CA3075423A1 (en) 2019-04-11

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