SG11202001140UA - Adiponectin peptidomimetics for treating ocular disorders - Google Patents

Adiponectin peptidomimetics for treating ocular disorders

Info

Publication number
SG11202001140UA
SG11202001140UA SG11202001140UA SG11202001140UA SG11202001140UA SG 11202001140U A SG11202001140U A SG 11202001140UA SG 11202001140U A SG11202001140U A SG 11202001140UA SG 11202001140U A SG11202001140U A SG 11202001140UA SG 11202001140U A SG11202001140U A SG 11202001140UA
Authority
SG
Singapore
Prior art keywords
ocular disorders
treating ocular
adiponectin peptidomimetics
adiponectin
peptidomimetics
Prior art date
Application number
SG11202001140UA
Other languages
English (en)
Inventor
Henry Hsu
Original Assignee
Allysta Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allysta Pharmaceuticals Inc filed Critical Allysta Pharmaceuticals Inc
Publication of SG11202001140UA publication Critical patent/SG11202001140UA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/5759Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Dermatology (AREA)
SG11202001140UA 2015-05-01 2018-08-07 Adiponectin peptidomimetics for treating ocular disorders SG11202001140UA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562156127P 2015-05-01 2015-05-01
US15/676,968 US10537608B2 (en) 2015-05-01 2017-08-14 Adiponectin peptidomimetics for treating ocular disorders
PCT/US2018/045527 WO2019036223A1 (en) 2015-05-01 2018-08-07 PEPTIDOMIMETICS OF ADIPONECTIN FOR THE TREATMENT OF OCULAR DISORDERS

Publications (1)

Publication Number Publication Date
SG11202001140UA true SG11202001140UA (en) 2020-03-30

Family

ID=57218292

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202001140UA SG11202001140UA (en) 2015-05-01 2018-08-07 Adiponectin peptidomimetics for treating ocular disorders

Country Status (12)

Country Link
US (6) US10987401B2 (https=)
EP (3) EP4014985A1 (https=)
JP (1) JP7245649B2 (https=)
KR (2) KR20170141692A (https=)
CN (3) CN115919996A (https=)
AU (3) AU2016257724B2 (https=)
CA (3) CA3191203A1 (https=)
DK (1) DK3288577T3 (https=)
ES (1) ES2903448T3 (https=)
IL (1) IL272449A (https=)
SG (1) SG11202001140UA (https=)
WO (2) WO2016179007A1 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115919996A (zh) 2015-05-01 2023-04-07 雅利斯塔制药公司 用于治疗眼科疾病的脂联素拟肽
WO2018165218A1 (en) * 2017-03-09 2018-09-13 Allysta Pharmaceuticals, Inc Peptides for dry eye disease
CN107149676A (zh) * 2017-05-05 2017-09-12 杨硕 脂联素和脂联素/胰岛素混合液在改善及治疗眼表角膜上皮及神经损伤中的应用
WO2019061491A1 (en) * 2017-09-30 2019-04-04 Pro Sunfun Biotech Research And Development Co., Ltd. PEPTIDE FOR OCULAR CARE, COMPOSITION AND METHOD OF USE THEREOF
CN109912685B (zh) * 2017-12-13 2022-05-06 三凡生技研发股份有限公司 眼睛保护胜肽及其组合物及使用该胜肽的用途
CN112165954A (zh) * 2018-03-23 2021-01-01 阿奇生物外科有限公司 用于治疗眼病的sap和拟肽
JP7688471B2 (ja) * 2018-10-24 2025-06-04 アリスタ ファーマスーティカルス インク. アディポネクチンペプチド模倣組成物
JP7699426B2 (ja) * 2018-11-30 2025-06-27 ロート製薬株式会社 光線による障害からの細胞保護用眼科組成物
US11229549B2 (en) * 2019-09-18 2022-01-25 Vance M. Thompson Tear transplantation and multi-part contact lens with absorbent portion
JP7419499B2 (ja) 2019-09-18 2024-01-22 アルコン インク. 湿式充填のソフトヒドロゲル眼用インサート
US11213551B1 (en) 2021-04-05 2022-01-04 Korb Research, Llc. Ocular treatment compositions and methods of use thereof
WO2023069549A1 (en) * 2021-10-20 2023-04-27 Stealth Biotherapeutics Inc. Methods and compositions comprising peptidomimitics for treating, preventing, inhibiting, ameliorating or delaying the onset of ophthalmic conditions
WO2023069255A1 (en) * 2021-10-20 2023-04-27 Stealth Biotherapeutics Inc. Methods and compositions comprising peptidomimitics for treating, preventing, inhibiting, ameliorating or delaying the onset of ophthalmic conditions
WO2023107796A1 (en) * 2021-12-11 2023-06-15 The Regents Of The University Of California Ophthalmic formulations for macular degeneration
WO2024180472A1 (en) 2023-02-28 2024-09-06 Alcon Inc. Ocular inserts
KR102609115B1 (ko) * 2023-06-08 2023-12-05 주식회사 엔큐라젠 펩타이드를 포함하는 안구 질환의 치료용 조성물

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US5108921A (en) 1989-04-03 1992-04-28 Purdue Research Foundation Method for enhanced transmembrane transport of exogenous molecules
US5643575A (en) 1993-10-27 1997-07-01 Enzon, Inc. Non-antigenic branched polymer conjugates
US5824784A (en) 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
DE4437604A1 (de) 1994-10-21 1996-04-25 Basf Ag Konjugate aus einem Poly- oder Oligopeptid und einer niedermolekularen lipophilen Verbindung
US5932462A (en) 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
EE05214B1 (et) 1998-04-28 2009-10-15 Applied Research Systems ARS Holding N.V. Polool-IFN- β konjugaat, selle valmistamismeetod ja farmatseutiline kompositsioon
GB9814527D0 (en) 1998-07-03 1998-09-02 Cyclacel Ltd Delivery system
CA2473781A1 (en) * 2002-01-18 2003-07-31 Protemix Corporation Limited Glycoisoforms of adiponectin and uses thereof
MX2007013430A (es) * 2005-04-29 2008-03-19 Univ California Peptidos y peptidos mimeticos para tratar patologias caracterizadas por una respuesta inflamatoria.
WO2012142142A2 (en) * 2011-04-12 2012-10-18 Temple University - Of The Commonwealth System Higher Education Adiponectin receptor agonists and methods of use
KR101438744B1 (ko) * 2012-08-02 2014-09-15 전남대학교산학협력단 아디포넥틴을 유효성분으로 포함하는 안구건조증 또는 염증성 안구표면 질환의 예방 또는 치료용 조성물
RU2652063C2 (ru) * 2012-10-26 2018-04-24 Форсайт Вижн5, Инк. Офтальмологическая система для замедленного высвобождения лекарственного средства в глазу
CN115919996A (zh) * 2015-05-01 2023-04-07 雅利斯塔制药公司 用于治疗眼科疾病的脂联素拟肽

Also Published As

Publication number Publication date
CA3191203A1 (en) 2016-11-10
AU2016257724B2 (en) 2021-02-25
KR20200039749A (ko) 2020-04-16
WO2019036223A1 (en) 2019-02-21
US20230074446A1 (en) 2023-03-09
AU2018318008A1 (en) 2020-02-06
WO2016179007A1 (en) 2016-11-10
US20200085907A1 (en) 2020-03-19
US20220331393A1 (en) 2022-10-20
US11273197B2 (en) 2022-03-15
JP2018514592A (ja) 2018-06-07
CN115919996A (zh) 2023-04-07
CA2981822C (en) 2023-04-11
EP4014985A1 (en) 2022-06-22
US20210128671A1 (en) 2021-05-06
KR20170141692A (ko) 2017-12-26
EP3288577A1 (en) 2018-03-07
IL272449A (en) 2020-03-31
EP3288577A4 (en) 2018-12-26
DK3288577T3 (da) 2022-01-10
US20180078616A1 (en) 2018-03-22
JP7245649B2 (ja) 2023-03-24
US11464825B2 (en) 2022-10-11
ES2903448T3 (es) 2022-04-01
HK1246178A1 (zh) 2018-09-07
CA2981822A1 (en) 2016-11-10
EP3668530A4 (en) 2021-07-21
AU2016257724A1 (en) 2017-10-12
EP3668530A1 (en) 2020-06-24
AU2021203254A1 (en) 2021-06-17
US10537608B2 (en) 2020-01-21
EP3288577B1 (en) 2021-10-27
CN107530396B (zh) 2022-08-26
CN107530396A (zh) 2018-01-02
US10987401B2 (en) 2021-04-27
US20180161390A1 (en) 2018-06-14
CA3071670A1 (en) 2019-02-21
CN111032070A (zh) 2020-04-17

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