SG11201912651WA - New salt of n-(2,6-diethylphenyl)-8-({4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl}am ino)-1-methyl-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide, its preparation and formulations containing it - Google Patents
New salt of n-(2,6-diethylphenyl)-8-({4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl}am ino)-1-methyl-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide, its preparation and formulations containing itInfo
- Publication number
- SG11201912651WA SG11201912651WA SG11201912651WA SG11201912651WA SG11201912651WA SG 11201912651W A SG11201912651W A SG 11201912651WA SG 11201912651W A SG11201912651W A SG 11201912651WA SG 11201912651W A SG11201912651W A SG 11201912651WA SG 11201912651W A SG11201912651W A SG 11201912651WA
- Authority
- SG
- Singapore
- Prior art keywords
- diethylphenyl
- ino
- pyrazolo
- quinazoline
- piperidin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Inorganic Chemistry (AREA)
- Virology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17305826 | 2017-06-29 | ||
PCT/EP2018/067394 WO2019002454A1 (en) | 2017-06-29 | 2018-06-28 | NOVEL N- (2,6-DIETHYLPHENYL) -8 - ({4- [4- (DIMETHYLAMINO) PIPERIDIN-1-YL] -2-METHOXYPHENYL} AMINO) -1-METHYL-4,5-DIHYDRO-1H SALT -PYRAZOLO [4,3-H] QUINAZOLINE-3-CARBOXAMIDE, ITS PREPARATION AND FORMULATIONS CONTAINING THE SAME |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201912651WA true SG11201912651WA (en) | 2020-01-30 |
Family
ID=59313166
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201912651WA SG11201912651WA (en) | 2017-06-29 | 2018-06-28 | New salt of n-(2,6-diethylphenyl)-8-({4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl}am ino)-1-methyl-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide, its preparation and formulations containing it |
Country Status (19)
Country | Link |
---|---|
US (2) | US11160806B2 (ja) |
EP (1) | EP3645535B1 (ja) |
JP (1) | JP7141416B2 (ja) |
KR (1) | KR102609333B1 (ja) |
CN (1) | CN110896636B (ja) |
AR (1) | AR112040A1 (ja) |
AU (1) | AU2018293729B9 (ja) |
BR (1) | BR112019027924A2 (ja) |
CA (1) | CA3068357C (ja) |
CL (1) | CL2019003848A1 (ja) |
EA (1) | EA039764B1 (ja) |
ES (1) | ES2900048T3 (ja) |
IL (1) | IL271628B2 (ja) |
MA (1) | MA49498A (ja) |
PL (1) | PL3645535T3 (ja) |
SG (1) | SG11201912651WA (ja) |
TW (1) | TWI750393B (ja) |
UY (1) | UY37778A (ja) |
WO (1) | WO2019002454A1 (ja) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2303891B1 (en) | 2008-06-26 | 2016-02-17 | Les Laboratoires Servier | Pyrazolo-quinazolines as protein kinase activity modulators |
-
2018
- 2018-06-21 UY UY0001037778A patent/UY37778A/es unknown
- 2018-06-28 AR ARP180101781A patent/AR112040A1/es unknown
- 2018-06-28 MA MA049498A patent/MA49498A/fr unknown
- 2018-06-28 SG SG11201912651WA patent/SG11201912651WA/en unknown
- 2018-06-28 EA EA202090115A patent/EA039764B1/ru unknown
- 2018-06-28 KR KR1020207002339A patent/KR102609333B1/ko active IP Right Grant
- 2018-06-28 ES ES18732820T patent/ES2900048T3/es active Active
- 2018-06-28 WO PCT/EP2018/067394 patent/WO2019002454A1/en unknown
- 2018-06-28 BR BR112019027924-5A patent/BR112019027924A2/pt unknown
- 2018-06-28 US US16/624,488 patent/US11160806B2/en active Active
- 2018-06-28 JP JP2019572116A patent/JP7141416B2/ja active Active
- 2018-06-28 CN CN201880043442.0A patent/CN110896636B/zh active Active
- 2018-06-28 CA CA3068357A patent/CA3068357C/en active Active
- 2018-06-28 EP EP18732820.8A patent/EP3645535B1/en active Active
- 2018-06-28 PL PL18732820T patent/PL3645535T3/pl unknown
- 2018-06-28 TW TW107122235A patent/TWI750393B/zh active
- 2018-06-28 AU AU2018293729A patent/AU2018293729B9/en active Active
-
2019
- 2019-12-22 IL IL271628A patent/IL271628B2/en unknown
- 2019-12-26 CL CL2019003848A patent/CL2019003848A1/es unknown
-
2021
- 2021-09-30 US US17/490,318 patent/US20220016122A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
TWI750393B (zh) | 2021-12-21 |
EP3645535A1 (en) | 2020-05-06 |
JP2020525477A (ja) | 2020-08-27 |
CN110896636B (zh) | 2022-07-19 |
US20200246339A1 (en) | 2020-08-06 |
AU2018293729B9 (en) | 2022-07-14 |
CA3068357C (en) | 2022-04-19 |
JP7141416B2 (ja) | 2022-09-22 |
KR20200020905A (ko) | 2020-02-26 |
EA039764B1 (ru) | 2022-03-11 |
AU2018293729A1 (en) | 2020-01-23 |
TW201904971A (zh) | 2019-02-01 |
IL271628B2 (en) | 2023-07-01 |
AU2018293729B2 (en) | 2022-03-10 |
CA3068357A1 (en) | 2019-01-03 |
UY37778A (es) | 2019-01-31 |
AR112040A1 (es) | 2019-09-11 |
WO2019002454A1 (en) | 2019-01-03 |
EA202090115A1 (ru) | 2020-05-25 |
CL2019003848A1 (es) | 2020-07-10 |
US11160806B2 (en) | 2021-11-02 |
CN110896636A (zh) | 2020-03-20 |
ES2900048T3 (es) | 2022-03-15 |
PL3645535T3 (pl) | 2022-03-21 |
KR102609333B1 (ko) | 2023-12-01 |
MA49498A (fr) | 2021-05-26 |
BR112019027924A2 (pt) | 2020-08-18 |
IL271628A (en) | 2020-02-27 |
EP3645535B1 (en) | 2021-09-08 |
US20220016122A1 (en) | 2022-01-20 |
IL271628B1 (en) | 2023-03-01 |
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