SG11201910864UA - Nanopore sequencers - Google Patents

Nanopore sequencers

Info

Publication number
SG11201910864UA
SG11201910864UA SG11201910864UA SG11201910864UA SG11201910864UA SG 11201910864U A SG11201910864U A SG 11201910864UA SG 11201910864U A SG11201910864U A SG 11201910864UA SG 11201910864U A SG11201910864U A SG 11201910864UA SG 11201910864U A SG11201910864U A SG 11201910864UA
Authority
SG
Singapore
Prior art keywords
nanopore sequencers
sequencers
nanopore
Prior art date
Application number
SG11201910864UA
Other languages
English (en)
Inventor
Boyan Boyanov
Rohan N Akolkar
Jeffrey S Fisher
Jeffrey G Mandell
Liangliang Qiang
Steven M Barnard
Original Assignee
Illumina Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Inc filed Critical Illumina Inc
Publication of SG11201910864UA publication Critical patent/SG11201910864UA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48707Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721Investigating individual macromolecules, e.g. by translocation through nanopores
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06Lysis of microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3278Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction involving nanosized elements, e.g. nanogaps or nanoparticles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44756Apparatus specially adapted therefor
    • G01N27/44791Microapparatus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48707Physical analysis of biological material of liquid biological material by electrical means

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Dispersion Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SG11201910864UA 2017-06-20 2018-06-19 Nanopore sequencers SG11201910864UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762522628P 2017-06-20 2017-06-20
PCT/US2018/038337 WO2018236906A2 (en) 2017-06-20 2018-06-19 SEQUENCERS BY NANOPORES

Publications (1)

Publication Number Publication Date
SG11201910864UA true SG11201910864UA (en) 2020-01-30

Family

ID=64737819

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201910864UA SG11201910864UA (en) 2017-06-20 2018-06-19 Nanopore sequencers

Country Status (14)

Country Link
US (1) US11567060B2 (zh)
EP (1) EP3642619B1 (zh)
JP (2) JP7272967B2 (zh)
KR (1) KR102451194B1 (zh)
CN (2) CN111247428B (zh)
AU (2) AU2018288767B2 (zh)
BR (1) BR112019024400A2 (zh)
CA (2) CA3178751A1 (zh)
IL (1) IL270753A (zh)
NZ (1) NZ759293A (zh)
RU (1) RU2747714C1 (zh)
SG (1) SG11201910864UA (zh)
WO (1) WO2018236906A2 (zh)
ZA (1) ZA201907624B (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2156179B1 (en) * 2007-04-04 2021-08-18 The Regents of The University of California Methods for using a nanopore
GB202016874D0 (en) 2020-10-23 2020-12-09 Oxford Nanopore Tech Ltd Nanopore support structure and manufacture thereof
WO2022211951A1 (en) * 2021-03-31 2022-10-06 Illumina, Inc. Nanopore sensor devices
US20240319165A1 (en) * 2021-11-15 2024-09-26 Illumina, Inc. Nanopore systems and methods of fabrication
WO2024075637A1 (ja) * 2022-10-04 2024-04-11 国立大学法人大阪大学 イオン電流測定方法およびイオン電流測定用デバイス

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7163658B2 (en) 2003-04-23 2007-01-16 Rouvain Bension Rapid sequencing of polymers
EP2156179B1 (en) 2007-04-04 2021-08-18 The Regents of The University of California Methods for using a nanopore
GB0717150D0 (en) 2007-09-04 2007-10-17 Univ Warwick Apparatus and method
US8940142B2 (en) 2008-05-05 2015-01-27 The Regents Of The University Of California Functionalized nanopipette biosensor
US20100025238A1 (en) * 2008-07-31 2010-02-04 Medtronic Minimed, Inc. Analyte sensor apparatuses having improved electrode configurations and methods for making and using them
US8986928B2 (en) 2009-04-10 2015-03-24 Pacific Biosciences Of California, Inc. Nanopore sequencing devices and methods
WO2011106314A2 (en) 2010-02-25 2011-09-01 Advanced Liquid Logic, Inc. Method of making nucleic acid libraries
US9005425B2 (en) * 2010-03-05 2015-04-14 University Of Utah Research Foundation Detection of nucleic acid lesions and adducts using nanopores
WO2011130312A1 (en) 2010-04-13 2011-10-20 Electronic Biosciences, Llc Synthetic hybrid nanopore devices and uses thereof
EA022475B1 (ru) 2010-10-19 2016-01-29 Ооо "Центр Инновационных Технологий-Нано" Способ секвенирования днк
KR101923241B1 (ko) 2011-03-04 2018-11-28 더 리전트 오브 더 유니버시티 오브 캘리포니아 가역적인 이온 및 분자 감지 또는 이동을 위한 나노세공 장치
CN103842519B (zh) 2011-04-04 2018-02-06 哈佛大学校长及研究员协会 通过局部电位测量进行的纳米孔感测
US11053535B2 (en) * 2011-09-12 2021-07-06 The University Of North Carolina At Chapel Hill Devices with a fluid transport nanochannel intersected by a fluid sensing nanochannel and related methods
CN104379761B (zh) 2012-04-09 2017-03-01 纽约哥伦比亚大学理事会 纳米孔的制备方法和其用途
KR20140012506A (ko) 2012-07-20 2014-02-03 삼성전자주식회사 비대칭 전해질 농도를 이용하여 생물분자를 분석하는 방법
JP6276182B2 (ja) 2012-08-17 2018-02-07 クオンタムバイオシステムズ株式会社 試料の分析方法
GB201313121D0 (en) * 2013-07-23 2013-09-04 Oxford Nanopore Tech Ltd Array of volumes of polar medium
WO2015127387A1 (en) * 2014-02-21 2015-08-27 Northeastern University Fluorescence-based analysis of biopolymers using nanopores
GB201418512D0 (en) * 2014-10-17 2014-12-03 Oxford Nanopore Tech Ltd Electrical device with detachable components
RU2014149813A (ru) 2014-12-09 2016-07-10 Сергей Александрович Аникин Способ нанопорового секвенирования днк
RU2713396C2 (ru) 2015-06-03 2020-02-05 Иллюмина, Инк. Композиции, системы и способы секвенирования полинуклеотидов с применением соединительных структур, прикрепленных к полимеразам, расположенным вблизи нанопор
CN108348819B (zh) 2015-10-30 2023-04-25 环球测序技术公司 用于控制dna、rna和其他生物分子穿过纳米孔的方法和系统
JP6579948B2 (ja) * 2015-12-24 2019-09-25 株式会社日立ハイテクノロジーズ 生体ポリマを分析するための測定試薬及び分析デバイス

Also Published As

Publication number Publication date
AU2018288767B2 (en) 2022-05-26
CA3178751A1 (en) 2018-12-27
CA3064273A1 (en) 2018-12-27
AU2022204030A1 (en) 2022-06-30
EP3642619B1 (en) 2024-07-31
BR112019024400A2 (pt) 2020-06-09
IL270753A (en) 2020-01-30
KR102451194B1 (ko) 2022-10-05
CN115326901B (zh) 2024-03-01
US11567060B2 (en) 2023-01-31
CN111247428A (zh) 2020-06-05
RU2747714C1 (ru) 2021-05-13
JP2020524271A (ja) 2020-08-13
CN115326901A (zh) 2022-11-11
AU2018288767A1 (en) 2019-12-05
JP2022043254A (ja) 2022-03-15
EP3642619A4 (en) 2021-06-16
WO2018236906A2 (en) 2018-12-27
CN111247428B (zh) 2022-08-23
WO2018236906A3 (en) 2019-03-07
JP7272967B2 (ja) 2023-05-12
CA3064273C (en) 2023-02-21
ZA201907624B (en) 2024-04-24
US20200132664A1 (en) 2020-04-30
EP3642619A2 (en) 2020-04-29
JP7285910B2 (ja) 2023-06-02
KR20200013691A (ko) 2020-02-07
NZ759293A (en) 2023-05-26

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