SG11201909240SA - Method for manufacturing diastereomer of citric acid derivative - Google Patents

Method for manufacturing diastereomer of citric acid derivative

Info

Publication number
SG11201909240SA
SG11201909240SA SG11201909240SA SG11201909240SA SG 11201909240S A SG11201909240S A SG 11201909240SA SG 11201909240S A SG11201909240S A SG 11201909240SA SG 11201909240S A SG11201909240S A SG 11201909240SA
Authority
SG
Singapore
Prior art keywords
citric acid
compound
diastereomer
manufacturing
aqueous solution
Prior art date
Application number
Other languages
English (en)
Inventor
Katsuya Hiraishi
Hiroyuki Soma
Fumie Jimma
Taro Adachi
Ippei Yamaoka
Naoyuki Endo
Original Assignee
Otsuka Pharma Factory Inc
Adabio Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Factory Inc, Adabio Co Ltd filed Critical Otsuka Pharma Factory Inc
Publication of SG11201909240SA publication Critical patent/SG11201909240SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/402,5-Pyrrolidine-diones
    • C07D207/4162,5-Pyrrolidine-diones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11201909240S 2017-04-28 2018-04-23 Method for manufacturing diastereomer of citric acid derivative SG11201909240SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017089725 2017-04-28
PCT/JP2018/016495 WO2018199040A1 (ja) 2017-04-28 2018-04-23 クエン酸誘導体のジアステレオマーの製造方法

Publications (1)

Publication Number Publication Date
SG11201909240SA true SG11201909240SA (en) 2019-11-28

Family

ID=63919139

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201909240S SG11201909240SA (en) 2017-04-28 2018-04-23 Method for manufacturing diastereomer of citric acid derivative

Country Status (13)

Country Link
US (1) US11155519B2 (ja)
EP (1) EP3617191B9 (ja)
JP (1) JP6826267B2 (ja)
KR (1) KR102299521B1 (ja)
CN (1) CN110546137B (ja)
AU (1) AU2018259992B2 (ja)
CA (1) CA3058886C (ja)
ES (1) ES2969457T3 (ja)
NZ (1) NZ757747A (ja)
PH (1) PH12019550273A1 (ja)
SG (1) SG11201909240SA (ja)
TW (1) TWI678360B (ja)
WO (1) WO2018199040A1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3372578A4 (en) * 2015-11-02 2019-11-13 Adabio Co.,Ltd. NOVEL CITRIC ACID DERIVATIVE
FR3091873B1 (fr) * 2019-01-17 2020-12-25 Guerbet Sa Complexe de gadolinium et d’un ligand chelateur derive de pcta diastereoisomeriquement enrichi et procede de preparation et de purification

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4842624B1 (ja) 1965-09-06 1973-12-13
JP2734265B2 (ja) 1991-12-12 1998-03-30 日本電気株式会社 エレクトレット・コンデンサ・マイクロフォン用増幅回路
JP4842624B2 (ja) 2005-11-25 2011-12-21 Ada Bio株式会社 オートファジー誘導用飲食品
JP5577129B2 (ja) 2010-03-26 2014-08-20 Ada Bio株式会社 ウイルス性肝炎患者における肝機能改善剤
CN105612194B (zh) 2013-10-11 2018-12-14 帝斯曼知识产权资产管理有限公司 聚合物和组合物
WO2016164437A1 (en) 2015-04-06 2016-10-13 The Penn State Research Foundation Luminescent compositions and applications thereof
EP3372578A4 (en) * 2015-11-02 2019-11-13 Adabio Co.,Ltd. NOVEL CITRIC ACID DERIVATIVE

Also Published As

Publication number Publication date
CN110546137A (zh) 2019-12-06
AU2018259992B2 (en) 2020-06-18
EP3617191A1 (en) 2020-03-04
EP3617191A4 (en) 2020-12-23
AU2018259992A1 (en) 2019-10-24
KR20190129965A (ko) 2019-11-20
CN110546137B (zh) 2023-10-31
US11155519B2 (en) 2021-10-26
JP6826267B2 (ja) 2021-02-03
JPWO2018199040A1 (ja) 2019-12-26
US20200055821A1 (en) 2020-02-20
TW201841887A (zh) 2018-12-01
CA3058886A1 (en) 2018-11-01
KR102299521B1 (ko) 2021-09-07
EP3617191B1 (en) 2023-12-20
PH12019550273A1 (en) 2021-01-04
CA3058886C (en) 2021-11-09
WO2018199040A1 (ja) 2018-11-01
NZ757747A (en) 2022-04-29
ES2969457T3 (es) 2024-05-20
TWI678360B (zh) 2019-12-01
EP3617191B9 (en) 2024-03-27

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