SG11201908691PA - Compounds and methods for the treatment of parasitic diseases - Google Patents

Compounds and methods for the treatment of parasitic diseases

Info

Publication number
SG11201908691PA
SG11201908691PA SG11201908691PA SG11201908691PA SG 11201908691P A SG11201908691P A SG 11201908691PA SG 11201908691P A SG11201908691P A SG 11201908691PA SG 11201908691P A SG11201908691P A SG 11201908691PA
Authority
SG
Singapore
Prior art keywords
international
massachusetts
cambridge
treatment
compounds
Prior art date
Application number
Other languages
English (en)
Inventor
Eamon Comer
Nobutaka Kato
Marshall Morningstar
Bruno Melillo
Original Assignee
Broad Inst Inc
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Broad Inst Inc, Harvard College filed Critical Broad Inst Inc
Publication of SG11201908691PA publication Critical patent/SG11201908691PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11201908691P 2017-03-20 2018-03-20 Compounds and methods for the treatment of parasitic diseases SG11201908691PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762473771P 2017-03-20 2017-03-20
PCT/US2018/023270 WO2018175385A1 (en) 2017-03-20 2018-03-20 Compounds and methods for the treatment of parasitic diseases

Publications (1)

Publication Number Publication Date
SG11201908691PA true SG11201908691PA (en) 2019-10-30

Family

ID=63586520

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201908691P SG11201908691PA (en) 2017-03-20 2018-03-20 Compounds and methods for the treatment of parasitic diseases

Country Status (17)

Country Link
US (2) US11174260B2 (es)
EP (1) EP3600286B1 (es)
JP (1) JP7306997B2 (es)
KR (1) KR20190129968A (es)
CN (1) CN110650738B (es)
AU (1) AU2018240031B2 (es)
BR (1) BR112019019494A2 (es)
CA (1) CA3057087A1 (es)
CO (1) CO2019011546A2 (es)
ES (1) ES2966369T3 (es)
IL (1) IL269390B (es)
MX (1) MX2019011271A (es)
MY (1) MY197171A (es)
PH (1) PH12019502150A1 (es)
SG (1) SG11201908691PA (es)
WO (1) WO2018175385A1 (es)
ZA (1) ZA201906213B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201908691PA (en) 2017-03-20 2019-10-30 Broad Inst Inc Compounds and methods for the treatment of parasitic diseases
CN110168093B (zh) * 2017-09-12 2023-08-15 中科蓝华(广州)生物医药技术有限公司 一种转染细胞内寄生虫的试剂盒及其应用
WO2020041384A1 (en) * 2018-08-20 2020-02-27 The Broad Institute, Inc. 3-phenyl-2-cyano-azetidine derivatives, inhibitors of rna-guided nuclease activity
US20220033404A1 (en) * 2018-09-18 2022-02-03 Washington University Treatment of infections of toxoplasma gondii and closely related parasites
EP3908587B1 (en) 2019-01-09 2024-05-22 Eisai R&D Management Co., Ltd. Method for synthesis of diazabicyclo[6.2.0]decane related compounds
US20230009323A1 (en) * 2019-10-25 2023-01-12 The Broad Institute, Inc. Compounds and methods for the treatment of cryptosporidiosis
WO2022067060A1 (en) * 2020-09-24 2022-03-31 The Broad Institute, Inc. Apicomplexan parasite inhibition

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3176017A (en) * 1963-02-26 1965-03-30 American Home Prod Aroylalkyl derivatives of diazabicyclo-nonanes and-decanes
US3542780A (en) 1967-07-25 1970-11-24 American Home Prod 2-amidino-1,2,3,4-tetrahydropyrazine(1,2-a)indoles
US3531485A (en) 1967-08-14 1970-09-29 American Home Prod Aryl-substituted diazabicycloalkanes
YU2101A (sh) 1998-07-14 2005-06-10 Bayer Aktiengesellschaft Antiparazitski derivati artemisinina (endoperoksidi)
UA77515C2 (en) 2002-04-04 2006-12-15 Diazabicyclo alkane derivatives possessing neuroldnin-nk1 receptor antagonistic activity
EP1698375B1 (en) 2003-12-25 2014-04-02 Ono Pharmaceutical Co., Ltd. Azetidine ring compounds and drugs comprising the same
CN105164124B (zh) * 2012-11-19 2017-03-15 诺华股份有限公司 用于治疗寄生虫疾病的化合物和组合物
SG10201703094UA (en) 2012-12-20 2017-06-29 Ucb Biopharma Sprl Therapeutically active pyrazolo-pyrimidine derivatives
UY35772A (es) 2013-10-14 2015-05-29 Bayer Cropscience Ag Nuevos compuestos plaguicidas
GB2533536B (en) 2013-10-24 2021-05-19 Toyota Motor Co Ltd Cathode active material for sodium batteries, and sodium battery
JP6591429B2 (ja) 2013-11-11 2019-10-16 ザ・ブロード・インスティテュート・インコーポレイテッド マラリアの治療のための化合物及び方法
US20160326157A1 (en) 2014-01-06 2016-11-10 President And Fellows Of Harvard College Monobactams and methods of their synthesis and use
LT3122745T (lt) 2014-03-24 2019-04-10 Novartis Ag Monobaktamo organiniai junginiai, skirti bakterinių infekcijų gydymui
SI3210973T1 (sl) 2014-10-24 2021-04-30 Takeda Pharmaceutical Company Limited Heteroarilne spojine za zdravljenje oftalmičnih bolezni
WO2016172631A2 (en) 2015-04-24 2016-10-27 President And Fellows Of Harvard College Substrate selective inhibitors of insulin-degrading enzyme (ide) and uses thereof
SG11201908691PA (en) 2017-03-20 2019-10-30 Broad Inst Inc Compounds and methods for the treatment of parasitic diseases
US20220033404A1 (en) 2018-09-18 2022-02-03 Washington University Treatment of infections of toxoplasma gondii and closely related parasites
WO2020219610A1 (en) 2019-04-23 2020-10-29 Washington University Compounds and methods for the treatment of parasitic diseases

Also Published As

Publication number Publication date
RU2019132950A3 (es) 2021-06-29
US11174260B2 (en) 2021-11-16
KR20190129968A (ko) 2019-11-20
MX2019011271A (es) 2020-01-20
CN110650738B (zh) 2023-05-09
EP3600286A4 (en) 2020-12-02
CN110650738A (zh) 2020-01-03
RU2019132950A (ru) 2021-04-21
US20200095253A1 (en) 2020-03-26
CA3057087A1 (en) 2018-09-27
CO2019011546A2 (es) 2020-02-28
ZA201906213B (en) 2022-03-30
US11866441B2 (en) 2024-01-09
IL269390A (en) 2019-11-28
JP2020514381A (ja) 2020-05-21
MY197171A (en) 2023-05-28
US20220162211A1 (en) 2022-05-26
WO2018175385A1 (en) 2018-09-27
EP3600286B1 (en) 2023-08-16
ES2966369T3 (es) 2024-04-22
JP7306997B2 (ja) 2023-07-11
BR112019019494A2 (pt) 2020-04-28
EP3600286A1 (en) 2020-02-05
IL269390B (en) 2022-08-01
AU2018240031B2 (en) 2022-07-14
AU2018240031A1 (en) 2019-10-10
PH12019502150A1 (en) 2020-07-06

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