SG11201902998SA - PROMOTER OF Hspa5 GENE - Google Patents

PROMOTER OF Hspa5 GENE

Info

Publication number
SG11201902998SA
SG11201902998SA SG11201902998SA SG11201902998SA SG11201902998SA SG 11201902998S A SG11201902998S A SG 11201902998SA SG 11201902998S A SG11201902998S A SG 11201902998SA SG 11201902998S A SG11201902998S A SG 11201902998SA SG 11201902998S A SG11201902998S A SG 11201902998SA
Authority
SG
Singapore
Prior art keywords
promoter
hspa5 gene
present
provides
cells
Prior art date
Application number
SG11201902998SA
Other languages
English (en)
Inventor
Kenji Masuda
Koichi Nonaka
Hiroki Tanemura
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of SG11201902998SA publication Critical patent/SG11201902998SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • C12N2015/8518—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic expressing industrially exogenous proteins, e.g. for pharmaceutical use, human insulin, blood factors, immunoglobulins, pseudoparticles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y306/00—Hydrolases acting on acid anhydrides (3.6)
    • C12Y306/04—Hydrolases acting on acid anhydrides (3.6) acting on acid anhydrides; involved in cellular and subcellular movement (3.6.4)
    • C12Y306/0401—Non-chaperonin molecular chaperone ATPase (3.6.4.10)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG11201902998SA 2016-10-03 2017-10-02 PROMOTER OF Hspa5 GENE SG11201902998SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016195564 2016-10-03
PCT/JP2017/035773 WO2018066492A1 (ja) 2016-10-03 2017-10-02 Ｈｓｐａ５遺伝子のプロモーター

Publications (1)

Publication Number Publication Date
SG11201902998SA true SG11201902998SA (en) 2019-05-30

Family

ID=61831803

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201912370RA SG10201912370RA (en) 2016-10-03 2017-10-02 PROMOTER OF Hspa5 GENE
SG11201902998SA SG11201902998SA (en) 2016-10-03 2017-10-02 PROMOTER OF Hspa5 GENE

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201912370RA SG10201912370RA (en) 2016-10-03 2017-10-02 PROMOTER OF Hspa5 GENE

Country Status (10)

Country Link
US (2) US11555204B2 (ja)
EP (1) EP3521428A4 (ja)
JP (2) JP7382138B2 (ja)
KR (1) KR102553990B1 (ja)
CN (1) CN109790539A (ja)
AU (1) AU2017340716A1 (ja)
CA (1) CA3039037C (ja)
SG (2) SG10201912370RA (ja)
TW (1) TWI812596B (ja)
WO (1) WO2018066492A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202020160A (zh) 2018-08-09 2020-06-01 日商第一三共股份有限公司 Hspa8 基因之啟動子
TW202146432A (zh) * 2020-04-03 2021-12-16 日商第一三共股份有限公司 新基因表現單元
WO2023210607A1 (ja) * 2022-04-26 2023-11-02 第一三共株式会社 Ｅｎｏ１遺伝子のプロモーター

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196523A (en) 1985-01-01 1993-03-23 The University Of Southern California Control of gene expression by glucose, calcium and temperature
JP3051411B2 (ja) 1989-03-14 2000-06-12 持田製薬株式会社 新規ｄｎａならびにそれを含有する発現プラスミド
SE468050C (sv) 1991-03-15 1998-02-11 Pharmacia & Upjohn Ab Rekombinant derivat av human faktor VIII
US7049132B1 (en) 1999-06-28 2006-05-23 University Of Southern California Stress-responsive induction of a therapeutic agent and methods of use
EP1284290A1 (en) 2001-08-08 2003-02-19 Aventis Behring GmbH Increase of the expression levels of factor VIII by insertion of spliceable nucleotide sequences into factor VIII cDNA
CN1454900A (zh) 2002-04-29 2003-11-12 上海复旦深慧基因科技有限公司 一种新的葡萄糖及胰岛素应答元件
WO2008073303A2 (en) 2006-12-07 2008-06-19 Switchgear Genomics Transcriptional regulatory elements of biological pathways, tools, and methods
CN101861391A (zh) 2007-08-10 2010-10-13 韦恩州立大学 通过翻译调控基因表达系统检测和调节细胞死亡的组合物和方法
US8815779B2 (en) 2009-09-16 2014-08-26 SwitchGear Genomics, Inc. Transcription biomarkers of biological responses and methods
EP3026117B1 (en) 2010-07-07 2018-09-12 Daiichi Sankyo Company, Limited Dna element having the activity of enhancing foreign gene expression
EP2787080B1 (en) 2011-11-28 2018-03-21 Daiichi Sankyo Company, Limited Promoter derived from human gene
SG10201803758XA (en) * 2013-02-01 2018-06-28 Selexis Sa Enhanced Transgene Expression and Processing

Also Published As

Publication number Publication date
CA3039037A1 (en) 2018-04-12
EP3521428A4 (en) 2020-06-24
US20190241907A1 (en) 2019-08-08
CA3039037C (en) 2021-08-31
TW201819631A (zh) 2018-06-01
JPWO2018066492A1 (ja) 2019-07-18
AU2017340716A2 (en) 2019-09-05
JP7382138B2 (ja) 2023-11-16
WO2018066492A1 (ja) 2018-04-12
SG10201912370RA (en) 2020-02-27
EP3521428A1 (en) 2019-08-07
AU2017340716A1 (en) 2019-05-02
JP2022136096A (ja) 2022-09-15
TWI812596B (zh) 2023-08-21
CN109790539A (zh) 2019-05-21
US11555204B2 (en) 2023-01-17
KR102553990B1 (ko) 2023-07-10
US20230257767A1 (en) 2023-08-17
KR20190056378A (ko) 2019-05-24

Similar Documents

Publication Publication Date Title
MX2017006127A (es) Metodos y composiciones para produccion de proteina de clara de huevo.
MX2020006117A (es) Integracion dirigida de acidos nucleicos.
ZA202201361B (en) Methods and compositions comprising purified recombinant polypeptides
WO2016022377A3 (en) Methods for modulating the glycosylation profile of recombinant proteins using dissolved oxygen
NZ722504A (en) Expression and purification of crm197 and related proteins
MX2014001383A (es) Colageno 7 y metodos relacionados.
BR112016020517A2 (pt) método de produção de lipídeo através da utilização de ss-cetoacil-acp sintase
MX2021001460A (es) Metodos y composiciones para secrecion de polipeptidos heterologos.
NZ742660A (en) Variants of chymosin with improved milk-clotting properties
MX2016008249A (es) Celulas eucariotas novedosas y metodos para la expresion recombinante de un producto de interes.
MX2016009149A (es) Variantes mejoradas de enzimas.
MX2016008258A (es) Celulas eucariotas novedosas y metodos para la expresion recombinante de un producto de interes.
MX2017000014A (es) Metodo para producir acido graso de cadena media con el uso de beta-cetoacil-proteina portadora de acilo (acp) sintasa.
MY169049A (en) Microorganisms for producing putrescine and process for producing putrescine using them
MX2015010078A (es) Uso de polipeptidos con actividad proteasa en alimentos para animales.
MY182519A (en) Method for producing lipid using acyl-acp thioesterase
SG11201902998SA (en) PROMOTER OF Hspa5 GENE
EP3448884C0 (en) MANIPULATED MAMMALIAN CELLS FOR THE PRODUCTION OF RECOMBINANT PROTEINS
MX2021014862A (es) Composiciones de proteina anti-vegf y metodos para producir la misma.
MY195726A (en) Steviol Glycoside Transport
MY194277A (en) Omega-hydroxylase-related fusion polypeptide variants with improved properties
MX2018009676A (es) Proceso.
MX2018003445A (es) Expresion de proteinas que contienen fc.
MX2021009154A (es) Selectividad eficaz de proteinas recombinantes.
MX2017015827A (es) Produccion de manool.