SG11201901937WA - Pyridine compound - Google Patents

Pyridine compound

Info

Publication number
SG11201901937WA
SG11201901937WA SG11201901937WA SG11201901937WA SG11201901937WA SG 11201901937W A SG11201901937W A SG 11201901937WA SG 11201901937W A SG11201901937W A SG 11201901937WA SG 11201901937W A SG11201901937W A SG 11201901937WA SG 11201901937W A SG11201901937W A SG 11201901937WA
Authority
SG
Singapore
Prior art keywords
chuo
tokyo
limited
international
honcho
Prior art date
Application number
SG11201901937WA
Other languages
English (en)
Inventor
Hiroaki Inagaki
Yoshihiro Shibata
Hidenori Namiki
Hideaki Kageji
Kiyoshi Nakayama
Yasuyuki Kaneta
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of SG11201901937WA publication Critical patent/SG11201901937WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
SG11201901937WA 2016-09-29 2017-09-28 Pyridine compound SG11201901937WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016191725A JP2018052878A (ja) 2016-09-29 2016-09-29 ピリジン化合物
PCT/GB2017/052913 WO2018060714A1 (en) 2016-09-29 2017-09-28 Pyridine compound

Publications (1)

Publication Number Publication Date
SG11201901937WA true SG11201901937WA (en) 2019-04-29

Family

ID=60020249

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201901937WA SG11201901937WA (en) 2016-09-29 2017-09-28 Pyridine compound

Country Status (32)

Country Link
US (2) US10851092B2 (sl)
EP (2) EP3519398B1 (sl)
JP (2) JP2018052878A (sl)
KR (1) KR102520543B1 (sl)
CN (2) CN110036007B (sl)
AU (2) AU2017335242C1 (sl)
BR (1) BR112019006047A2 (sl)
CA (1) CA3035860A1 (sl)
CL (1) CL2019000844A1 (sl)
CO (1) CO2019004034A2 (sl)
CY (1) CY1123988T1 (sl)
DK (1) DK3519398T3 (sl)
EA (1) EA037103B1 (sl)
EC (1) ECSP19030134A (sl)
ES (1) ES2868748T3 (sl)
HR (1) HRP20210447T1 (sl)
HU (1) HUE054824T2 (sl)
IL (1) IL265630B (sl)
LT (1) LT3519398T (sl)
MA (2) MA46337B1 (sl)
MD (1) MD3519398T2 (sl)
MX (1) MX2019003747A (sl)
PE (1) PE20190805A1 (sl)
PH (1) PH12019500480A1 (sl)
PL (1) PL3519398T3 (sl)
PT (1) PT3519398T (sl)
RS (1) RS61640B1 (sl)
SG (1) SG11201901937WA (sl)
SI (1) SI3519398T1 (sl)
UA (1) UA123964C2 (sl)
WO (1) WO2018060714A1 (sl)
ZA (1) ZA201902232B (sl)

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KR20180073689A (ko) 2015-11-02 2018-07-02 블루프린트 메디신즈 코포레이션 Ret의 저해제
JP2018052878A (ja) * 2016-09-29 2018-04-05 第一三共株式会社 ピリジン化合物
US11472802B2 (en) 2018-01-18 2022-10-18 Array Biopharma Inc. Substituted pyrazolyl[4,3-c]pyridine compounds as RET kinase inhibitors
TWI802635B (zh) 2018-01-18 2023-05-21 美商亞雷生物製藥股份有限公司 作為ret激酶抑制劑之經取代吡咯并[2,3-d]嘧啶化合物
LT3773589T (lt) 2018-04-03 2024-02-12 Blueprint Medicines Corporation Ret inhibitorius, skirtas naudoti vėžiui gydyti, esant ret pakitimui
CN114364798A (zh) 2019-03-21 2022-04-15 欧恩科斯欧公司 用于治疗癌症的Dbait分子与激酶抑制剂的组合
KR20220098759A (ko) 2019-11-08 2022-07-12 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) 키나제 억제제에 대해 내성을 획득한 암의 치료 방법
US20230019999A1 (en) * 2019-11-18 2023-01-19 Chugai Seiyaku Kabushiki Kaisha Combination drug
CN113121524B (zh) 2019-12-31 2023-04-25 南京创济生物医药有限公司 杂环亚砜亚胺化合物及其中间体、制备方法和应用
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use
JP7461605B2 (ja) * 2020-02-20 2024-04-04 広州白雲山医薬集団股▲フン▼有限公司白雲山制薬総廠 キノリン系化合物
WO2021164741A1 (zh) * 2020-02-20 2021-08-26 南京明德新药研发有限公司 苯基双酰胺类化合物
WO2022238706A1 (en) 2021-05-14 2022-11-17 Bp Asset Viii, Inc. Ret inhibitor for the treatment of ret altered medullary thyroid cancer or ret altered non-small cell lung cancer
CA3234317A1 (en) 2021-10-22 2023-12-14 Wa Xian Methods and compositions for treating chronic inflammatory injury, metaplasia, dysplasia and cancers of epithelial tissues
CN115090331B (zh) * 2022-07-21 2023-05-16 扬州大学 超分子手性催化剂、其制备方法及其催化d-a反应的应用

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Publication number Priority date Publication date Assignee Title
TWI284639B (en) 2000-01-24 2007-08-01 Shionogi & Co A compound having thrombopoietin receptor agonistic effect
CN102060806A (zh) 2003-09-11 2011-05-18 iTherX药品公司 细胞因子抑制剂
US20090233950A1 (en) 2006-03-02 2009-09-17 Frederic Henri Jung Quinazoline derivatives
US20090076075A1 (en) 2006-03-02 2009-03-19 Frederic Henri Jung Quinoline derivatives
WO2007113565A1 (en) 2006-04-06 2007-10-11 Astrazeneca Ab Naphthyridine derivatives as anti-cancer agents
WO2007113548A1 (en) 2006-04-06 2007-10-11 Astrazeneca Ab Naphthyridine derivatives
FR2933700B1 (fr) 2008-07-08 2010-07-30 Sanofi Aventis Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique
TWI466874B (zh) * 2009-02-27 2015-01-01 Teijin Pharma Ltd A method for producing a heterocyclic derivative of a phenyl group substituted by a coupling method using a transition metal catalyst
US20130035326A1 (en) 2009-08-19 2013-02-07 Ambit Biosciences Corporation Biaryl compounds and methods of use thereof
SG178873A1 (en) 2009-08-25 2012-04-27 Abraxis Bioscience Llc Combination therapy with nanoparticle compositions of taxane and hedgehog inhibitors
JP2013527159A (ja) 2010-04-23 2013-06-27 キネタ・インコーポレイテツド 抗ウイルス性化合物
WO2012082817A1 (en) 2010-12-16 2012-06-21 Boehringer Ingelheim International Gmbh Biarylamide inhibitors of leukotriene production
EP2872493B1 (en) 2012-07-13 2018-11-14 Indiana University Research and Technology Corporation 5,6,7-trimethoxy 4-phenyl quinolin-2-one derivatives for treatment of spinal muscular atrophy
BR112015023618A2 (pt) * 2013-03-15 2017-07-18 Glaxosmithkline Ip Dev Ltd derivados de piridina como inibidores de quinase reorganizada durante a transfecção (ret)
MX2016002626A (es) 2013-08-30 2016-06-06 Ambit Biosciences Corp Compuestos de biarilacetamida y metodos de uso de los mismos.
GB201321146D0 (en) 2013-11-29 2014-01-15 Cancer Rec Tech Ltd Quinazoline compounds
JPWO2015163435A1 (ja) * 2014-04-24 2017-04-20 田辺三菱製薬株式会社 新規2−アミノ−ピリジン及び2−アミノ−ピリミジン誘導体及びその医薬用途
DK3191449T3 (da) * 2014-09-10 2020-08-03 Glaxosmithkline Ip Dev Ltd Forbindelser som ret- (rearranged during transfection) hæmmere
BR112017004900A2 (pt) * 2014-09-10 2017-12-12 Glaxosmithkline Ip Dev Ltd derivados de piridona como inibidores de quinase rearranjada durante transfecção (ret)
JP6899323B2 (ja) 2014-10-14 2021-07-07 ラ ホーヤ インスティテュート オブ アレルギー アンド イミュノロジー 低分子量タンパク質チロシンホスファターゼの阻害剤、及びその使用
CN104844589B (zh) 2014-12-26 2018-04-20 中国科学院合肥物质科学研究院 一种pi3k激酶抑制剂
US10202365B2 (en) * 2015-02-06 2019-02-12 Blueprint Medicines Corporation 2-(pyridin-3-yl)-pyrimidine derivatives as RET inhibitors
AU2016291676B2 (en) 2015-07-16 2020-04-30 Array Biopharma, Inc. Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors
JP2018052878A (ja) * 2016-09-29 2018-04-05 第一三共株式会社 ピリジン化合物

Also Published As

Publication number Publication date
CA3035860A1 (en) 2018-04-05
AU2021261899A1 (en) 2021-12-02
MA54910A (fr) 2022-04-13
PE20190805A1 (es) 2019-06-10
AU2017335242C1 (en) 2021-12-09
CN110036007A (zh) 2019-07-19
AU2017335242B2 (en) 2021-08-19
BR112019006047A2 (pt) 2019-06-25
MX2019003747A (es) 2019-09-19
SI3519398T1 (sl) 2021-07-30
MD3519398T2 (ro) 2021-05-31
KR102520543B1 (ko) 2023-04-10
CO2019004034A2 (es) 2019-07-10
PT3519398T (pt) 2021-03-24
JP2019534871A (ja) 2019-12-05
HUE054824T2 (hu) 2021-10-28
US20200039974A1 (en) 2020-02-06
EA201990833A1 (ru) 2019-10-31
CN110036007B (zh) 2021-10-15
KR20190086442A (ko) 2019-07-22
HRP20210447T1 (hr) 2021-07-23
US20210163464A1 (en) 2021-06-03
WO2018060714A1 (en) 2018-04-05
CY1123988T1 (el) 2022-05-27
US10851092B2 (en) 2020-12-01
LT3519398T (lt) 2021-05-10
CL2019000844A1 (es) 2019-06-07
ZA201902232B (en) 2022-12-21
ES2868748T3 (es) 2021-10-21
JP7098609B2 (ja) 2022-07-11
UA123964C2 (uk) 2021-06-30
IL265630B (en) 2021-10-31
MA46337A (fr) 2019-08-07
EP3519398B1 (en) 2021-02-24
IL265630A (en) 2019-05-30
AU2017335242A1 (en) 2019-05-02
JP2018052878A (ja) 2018-04-05
DK3519398T3 (da) 2021-03-29
EP3828178A1 (en) 2021-06-02
PH12019500480A1 (en) 2019-08-05
CN113788824A (zh) 2021-12-14
RS61640B1 (sr) 2021-04-29
EA037103B1 (ru) 2021-02-05
ECSP19030134A (es) 2019-08-30
EP3519398A1 (en) 2019-08-07
MA46337B1 (fr) 2021-04-30
PL3519398T3 (pl) 2021-06-28

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