SG11201900096QA - Novel processes for preparation of soluble guanylate cyclase stimulators - Google Patents

Novel processes for preparation of soluble guanylate cyclase stimulators

Info

Publication number
SG11201900096QA
SG11201900096QA SG11201900096QA SG11201900096QA SG11201900096QA SG 11201900096Q A SG11201900096Q A SG 11201900096QA SG 11201900096Q A SG11201900096Q A SG 11201900096QA SG 11201900096Q A SG11201900096Q A SG 11201900096QA SG 11201900096Q A SG11201900096Q A SG 11201900096QA
Authority
SG
Singapore
Prior art keywords
international
preparation
massachusetts
pct
guanylate cyclase
Prior art date
Application number
SG11201900096QA
Other languages
English (en)
Inventor
Song Xue
Vishnu Vardhan Reddy Karnati
Robert C Livingston
Original Assignee
Ironwood Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ironwood Pharmaceuticals Inc filed Critical Ironwood Pharmaceuticals Inc
Publication of SG11201900096QA publication Critical patent/SG11201900096QA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11201900096QA 2016-07-07 2017-07-06 Novel processes for preparation of soluble guanylate cyclase stimulators SG11201900096QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662359453P 2016-07-07 2016-07-07
PCT/US2017/040810 WO2018009597A1 (en) 2016-07-07 2017-07-06 Novel processes for preparation of soluble guanylate cyclase stimulators

Publications (1)

Publication Number Publication Date
SG11201900096QA true SG11201900096QA (en) 2019-02-27

Family

ID=59416789

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201900096QA SG11201900096QA (en) 2016-07-07 2017-07-06 Novel processes for preparation of soluble guanylate cyclase stimulators

Country Status (16)

Country Link
US (3) US11319308B2 (ru)
EP (2) EP4249488A3 (ru)
JP (1) JP7112384B2 (ru)
KR (1) KR102487872B1 (ru)
CN (1) CN109563077A (ru)
AU (1) AU2017291827B2 (ru)
BR (1) BR112019000291A2 (ru)
CA (1) CA3029375A1 (ru)
CL (2) CL2019000016A1 (ru)
EA (1) EA201990237A1 (ru)
ES (1) ES2963563T3 (ru)
IL (1) IL263995B (ru)
MA (1) MA45603A (ru)
MX (2) MX2019000105A (ru)
SG (1) SG11201900096QA (ru)
WO (1) WO2018009597A1 (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10202100168XA (en) * 2016-07-07 2021-02-25 Cyclerion Therapeutics Inc Novel processes for preparation of soluble guanylate cyclase stimulators
MA45603A (fr) 2016-07-07 2019-05-15 Ironwood Pharmaceuticals Inc Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble
SG11202006311SA (en) 2018-01-10 2020-07-29 Cyclerion Therapeutics Inc Novel processes and intermediates for the preparation of soluble guanylate cyclase stimulators
WO2019161534A1 (en) * 2018-02-22 2019-08-29 Ironwood Pharmaceuticals, Inc. Novel processes and intermediates for preparation of soluble guanylate cyclase stimulators

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8969349B2 (en) 2010-05-26 2015-03-03 Sunovion Pharmaceuticals Inc. Substituted quinoxalines and quinoxalinones as PDE-10 inhibitors
WO2012003405A1 (en) 2010-06-30 2012-01-05 Ironwood Pharmaceuticals, Inc. Sgc stimulators
EP2797915B1 (en) * 2011-12-27 2016-07-13 Ironwood Pharmaceuticals, Inc. 2-benzyl-3-(oxazole/thiazole)-5-(pyrimidin-2-yl)-1(H)-pyrazole derivatives as stimulators of the soluble guanylate cyclase (sGC) for the treatment of e.g. hypertension or heart failure
EP2897953B8 (en) * 2012-09-19 2019-06-26 Cyclerion Therapeutics, Inc. Sgc stimulators
SI3660013T1 (sl) * 2013-03-15 2022-05-31 Cyclerion Therapeutics, Inc. SGC stimulatorji
EP3092231B1 (en) 2013-12-11 2018-06-27 Ironwood Pharmaceuticals, Inc. Sgc stimulators
EP3194382B1 (en) * 2014-09-17 2021-09-08 Cyclerion Therapeutics, Inc. Pyrazole derivatives as sgc stimulators
JP2017527604A (ja) * 2014-09-17 2017-09-21 アイアンウッド ファーマシューティカルズ インコーポレイテッド sGC刺激剤
EP3194395B1 (en) * 2014-09-17 2019-12-04 Cyclerion Therapeutics, Inc. Sgc stimulators
WO2016044445A2 (en) * 2014-09-17 2016-03-24 Ironwood Pharmaceuticals, Inc. sGC STIMULATORS
EA201891315A1 (ru) 2015-11-30 2018-12-28 Айронвуд Фармасьютикалз, Инк. Твердые дисперсии, содержащие стимулятор sgc
EP3481820B1 (en) 2016-07-07 2023-10-18 Cyclerion Therapeutics, Inc. Solid forms of an sgc stimulator
MA45603A (fr) 2016-07-07 2019-05-15 Ironwood Pharmaceuticals Inc Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble
SG10202100168XA (en) * 2016-07-07 2021-02-25 Cyclerion Therapeutics Inc Novel processes for preparation of soluble guanylate cyclase stimulators
CA3086207A1 (en) * 2017-12-19 2019-06-27 Cyclerion Therapeutics, Inc. Sgc stimulators
SG11202006311SA (en) * 2018-01-10 2020-07-29 Cyclerion Therapeutics Inc Novel processes and intermediates for the preparation of soluble guanylate cyclase stimulators

Also Published As

Publication number Publication date
US20220227748A1 (en) 2022-07-21
EP3481818B1 (en) 2023-09-06
WO2018009597A1 (en) 2018-01-11
EP4249488A2 (en) 2023-09-27
EA201990237A1 (ru) 2019-08-30
EP4249488A3 (en) 2023-12-20
EP3481818C0 (en) 2023-09-06
BR112019000291A2 (pt) 2019-04-16
US11773089B2 (en) 2023-10-03
MA45603A (fr) 2019-05-15
CN109563077A (zh) 2019-04-02
KR20190025986A (ko) 2019-03-12
CL2023000228A1 (es) 2023-09-29
CL2019000016A1 (es) 2019-05-03
EP3481818A1 (en) 2019-05-15
US20240059684A1 (en) 2024-02-22
ES2963563T3 (es) 2024-03-27
JP2019525913A (ja) 2019-09-12
MX2019000105A (es) 2019-04-22
KR102487872B1 (ko) 2023-01-12
IL263995A (en) 2019-02-28
IL263995B (en) 2021-02-28
US20210323951A1 (en) 2021-10-21
CA3029375A1 (en) 2018-01-11
MX2022001495A (es) 2022-03-11
AU2017291827B2 (en) 2021-10-21
US11319308B2 (en) 2022-05-03
AU2017291827A1 (en) 2019-02-07
JP7112384B2 (ja) 2022-08-03

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