SG11201810725WA - Novel β-lactamase inhibitors - Google Patents

Novel β-lactamase inhibitors

Info

Publication number
SG11201810725WA
SG11201810725WA SG11201810725WA SG11201810725WA SG11201810725WA SG 11201810725W A SG11201810725W A SG 11201810725WA SG 11201810725W A SG11201810725W A SG 11201810725WA SG 11201810725W A SG11201810725W A SG 11201810725WA SG 11201810725W A SG11201810725W A SG 11201810725WA
Authority
SG
Singapore
Prior art keywords
lactamase inhibitors
novel
disclosed
lactamase
novelb
Prior art date
Application number
SG11201810725WA
Other languages
English (en)
Inventor
Boyu Hu
Charles Z Ding
Zhigang Huang
Ruibin Lin
Minliang Xiao
Jinsheng Xie
Shuhui Chen
Cheng Li
Original Assignee
Medshine Discovery Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medshine Discovery Inc filed Critical Medshine Discovery Inc
Publication of SG11201810725WA publication Critical patent/SG11201810725WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11201810725WA 2016-06-03 2017-06-02 Novel β-lactamase inhibitors SG11201810725WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201610394846 2016-06-03
PCT/CN2017/086999 WO2017206947A1 (zh) 2016-06-03 2017-06-02 新型β-内酰胺酶抑制剂

Publications (1)

Publication Number Publication Date
SG11201810725WA true SG11201810725WA (en) 2018-12-28

Family

ID=60477996

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201810725WA SG11201810725WA (en) 2016-06-03 2017-06-02 Novel β-lactamase inhibitors

Country Status (13)

Country Link
US (1) US10738051B2 (de)
EP (1) EP3466950B1 (de)
JP (1) JP6929881B2 (de)
KR (1) KR102392350B1 (de)
CN (1) CN109311881B (de)
AU (1) AU2017274131B2 (de)
CA (1) CA3026322C (de)
ES (1) ES2863725T3 (de)
MY (1) MY193239A (de)
RU (1) RU2741963C2 (de)
SG (1) SG11201810725WA (de)
WO (1) WO2017206947A1 (de)
ZA (1) ZA201808552B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2928152T3 (es) * 2017-12-01 2022-11-15 Qilu Pharmaceutical Co Ltd Forma cristalina de un inhibidor de beta-lactamasa y método de preparación de la misma
CN111511737B (zh) * 2018-01-29 2022-10-18 南京明德新药研发有限公司 用于治疗细菌感染的单环β-内酰胺化合物
EP3978506A4 (de) * 2019-05-30 2022-08-31 Zhuohe Pharmaceutical Group Co., Ltd Antibakterielle aminoglykosidderivate
WO2021121387A1 (zh) * 2019-12-19 2021-06-24 南京明德新药研发有限公司 化合物在制药中的应用
CN113292499B (zh) * 2020-02-24 2024-05-28 齐鲁制药有限公司 一种β-内酰胺酶抑制剂的新制备方法及其中间体

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100463403C (zh) * 2006-03-20 2009-02-18 腾讯科技(深圳)有限公司 一种基于点对点技术的图片共享系统和方法
JP4809097B2 (ja) * 2006-03-29 2011-11-02 ルネサスエレクトロニクス株式会社 受信回路及び受信方法
CN103649051B (zh) 2011-06-17 2016-04-13 阿斯利康(瑞典)有限公司 制备包括反-7-氧代-6-(磺基氧基)-1,6-二氮杂二环[3,2,1]辛烷-2-甲酰胺的杂环化合物及其盐的方法
US9505761B2 (en) * 2011-12-02 2016-11-29 Fedora Pharmaceuticals Inc. Bicyclic compounds and their use as antibacterial agents and beta-lactamase inhibitors
US8796257B2 (en) 2011-12-02 2014-08-05 Naeja Pharmaceutical Inc. Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors
TW201343646A (zh) * 2012-03-30 2013-11-01 Cubist Pharm Inc 異□唑β-內醯胺酶抑制劑
SG10201605368UA (en) 2012-05-30 2016-08-30 Meiji Seika Pharma Co Ltd NOVEL β-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME
US20150203503A1 (en) 2012-08-25 2015-07-23 Wockhardt Limited 1,6- diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections
UA111925C2 (uk) * 2012-12-11 2016-06-24 Федора Фармасьютікалз Інк. БІЦИКЛІЧНІ СПОЛУКИ ТА ЇХ ВИКОРИСТАННЯ ЯК АНТИБАКТЕРІАЛЬНИХ АГЕНТІВ ТА ІНГІБІТОРІВ β-ЛАКТАМАЗИ

Also Published As

Publication number Publication date
KR20190015350A (ko) 2019-02-13
EP3466950B1 (de) 2021-02-24
RU2018146128A3 (de) 2020-07-10
JP6929881B2 (ja) 2021-09-01
US10738051B2 (en) 2020-08-11
CN109311881B (zh) 2021-07-13
WO2017206947A1 (zh) 2017-12-07
ES2863725T3 (es) 2021-10-11
CA3026322C (en) 2023-08-15
EP3466950A4 (de) 2019-11-20
CN109311881A (zh) 2019-02-05
ZA201808552B (en) 2022-11-30
EP3466950A1 (de) 2019-04-10
MY193239A (en) 2022-09-27
CA3026322A1 (en) 2017-12-07
KR102392350B1 (ko) 2022-04-29
RU2741963C2 (ru) 2021-02-01
US20200010467A1 (en) 2020-01-09
AU2017274131A1 (en) 2019-01-24
AU2017274131B2 (en) 2020-10-08
JP2019517501A (ja) 2019-06-24
RU2018146128A (ru) 2020-07-10

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