SG11201810123SA - Treatment of intrahepatic cholestatic diseases - Google Patents

Treatment of intrahepatic cholestatic diseases

Info

Publication number
SG11201810123SA
SG11201810123SA SG11201810123SA SG11201810123SA SG11201810123SA SG 11201810123S A SG11201810123S A SG 11201810123SA SG 11201810123S A SG11201810123S A SG 11201810123SA SG 11201810123S A SG11201810123S A SG 11201810123SA SG 11201810123S A SG11201810123S A SG 11201810123SA
Authority
SG
Singapore
Prior art keywords
international
suite
newark
pct
treatment
Prior art date
Application number
SG11201810123SA
Other languages
English (en)
Inventor
Pol Boudes
Charles Mcwherter
Original Assignee
Cymabay Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cymabay Therapeutics Inc filed Critical Cymabay Therapeutics Inc
Publication of SG11201810123SA publication Critical patent/SG11201810123SA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SG11201810123SA 2016-05-31 2017-04-26 Treatment of intrahepatic cholestatic diseases SG11201810123SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662343688P 2016-05-31 2016-05-31
PCT/US2017/029620 WO2017209865A1 (en) 2016-05-31 2017-04-26 Treatment of intrahepatic cholestatic diseases

Publications (1)

Publication Number Publication Date
SG11201810123SA true SG11201810123SA (en) 2018-12-28

Family

ID=58699276

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201810123SA SG11201810123SA (en) 2016-05-31 2017-04-26 Treatment of intrahepatic cholestatic diseases

Country Status (25)

Country Link
US (5) US10272058B2 (hu)
EP (1) EP3463328B1 (hu)
JP (1) JP7079735B2 (hu)
KR (1) KR102408288B1 (hu)
CN (1) CN109195594A (hu)
AU (1) AU2017274293B2 (hu)
BR (1) BR112018074147A2 (hu)
CA (1) CA3024155C (hu)
DK (1) DK3463328T3 (hu)
ES (1) ES2921230T3 (hu)
HR (1) HRP20220903T1 (hu)
HU (1) HUE059838T2 (hu)
IL (1) IL263372B2 (hu)
LT (1) LT3463328T (hu)
MX (1) MX2018014915A (hu)
NZ (1) NZ748721A (hu)
PL (1) PL3463328T3 (hu)
PT (1) PT3463328T (hu)
RS (1) RS63345B1 (hu)
RU (1) RU2765460C2 (hu)
SG (1) SG11201810123SA (hu)
SI (1) SI3463328T1 (hu)
UA (1) UA122719C2 (hu)
WO (1) WO2017209865A1 (hu)
ZA (1) ZA201808360B (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10272058B2 (en) 2014-03-20 2019-04-30 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
MX367478B (es) 2014-03-20 2019-08-23 Cymaby Therapeutics Inc Tratamiento de enfermedades colestasicas intrahepaticas.
US10512622B2 (en) 2017-07-14 2019-12-24 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
US20200155650A1 (en) * 2018-11-16 2020-05-21 Cymabay Therapeutics, Inc. Combination treatment of NAFLD and NASH
IL304873A (en) * 2021-02-01 2023-10-01 Cymabay Therapeutics Inc Treatment of cholangiopathy with saldalafar

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7101993B1 (en) 1990-01-11 2006-09-05 Isis Pharmaceuticals, Inc. Oligonucleotides containing 2′-O-modified purines
US7015315B1 (en) 1991-12-24 2006-03-21 Isis Pharmaceuticals, Inc. Gapped oligonucleotides
US5739135A (en) 1993-09-03 1998-04-14 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US6222025B1 (en) 1995-03-06 2001-04-24 Isis Pharmaceuticals, Inc. Process for the synthesis of 2′-O-substituted pyrimidines and oligomeric compounds therefrom
US6166197A (en) 1995-03-06 2000-12-26 Isis Pharmaceuticals, Inc. Oligomeric compounds having pyrimidine nucleotide (S) with 2'and 5 substitutions
BR9707529A (pt) 1996-02-14 2000-01-04 Isis Pharmaceuticals Inc Oligunucleotìdeo especificamente hibridizável com dna ou rna.
US5883109A (en) 1996-07-24 1999-03-16 Bristol-Myers Squibb Company Method for lowering serum lipid levels employing an MTP inhibitor in combination with another cholesterol lowering drug
US6066653A (en) 1997-01-17 2000-05-23 Bristol-Myers Squibb Co. Method of treating acid lipase deficiency diseases with an MTP inhibitor and cholesterol lowering drugs
US7407943B2 (en) 2001-08-01 2008-08-05 Isis Pharmaceuticals, Inc. Antisense modulation of apolipoprotein B expression
US7511131B2 (en) 2002-11-13 2009-03-31 Genzyme Corporation Antisense modulation of apolipoprotein B expression
US7981915B2 (en) 2003-04-30 2011-07-19 Beth Israel Deaconess Medical Center Methods for modulating PPAR biological activity for the treatment of diseases caused by mutations in the CFTR gene
EP2100877B1 (en) 2003-09-19 2012-01-25 Janssen Pharmaceutica N.V. 4-((Phenoxyalkyl)thio)-phenoxyacetic acids and analogs
SI1725234T1 (sl) 2004-03-05 2013-04-30 The Trustees Of The University Of Pennsylvania Postopki zdravljenja nepravilnosti ali bolezni povezanih s hiperlipidemijo in hiperholesterolemijo z minimiziranjem stranskih uäśinkov
JO3006B1 (ar) 2005-09-14 2016-09-05 Janssen Pharmaceutica Nv املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك
EP2346498B1 (en) 2008-10-17 2018-12-26 Cymabay Therapeutics, Inc. Methods of reducing small, dense ldl particles
NZ789295A (en) * 2009-04-29 2024-02-23 Amarin Pharmaceuticals Ie Ltd Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
AU2011235301B2 (en) 2010-03-30 2013-07-18 Novartis Ag Uses of DGAT1 inhibitors
JOP20200043A1 (ar) 2011-05-10 2017-06-16 Amgen Inc طرق معالجة أو منع الاضطرابات المختصة بالكوليسترول
US20150139987A1 (en) 2013-11-20 2015-05-21 Cymabay Therapeutics, Inc. Treatment of homozygous familial hypercholesterolemia
US20160279085A1 (en) 2013-11-20 2016-09-29 Cymabay Therapeutics, Inc. Treatment of Severe Hyperlipidemia
US10272058B2 (en) 2014-03-20 2019-04-30 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
MX367478B (es) 2014-03-20 2019-08-23 Cymaby Therapeutics Inc Tratamiento de enfermedades colestasicas intrahepaticas.
KR102374499B1 (ko) 2014-04-11 2022-03-14 사이머베이 쎄라퓨틱스, 인코퍼레이티드 Nafld 및 nash 의 치료
WO2015200580A1 (en) 2014-06-26 2015-12-30 Cymabay Therapeutics, Inc. Treatment of severe hypertriglyceridemia
US10512622B2 (en) 2017-07-14 2019-12-24 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
PL3687523T3 (pl) 2017-09-26 2022-02-21 Cymabay Therapeutics, Inc. Leczenie świądu cholestatycznego za pomocą seladelparu
US20200155650A1 (en) 2018-11-16 2020-05-21 Cymabay Therapeutics, Inc. Combination treatment of NAFLD and NASH
MX2021005725A (es) 2018-11-16 2021-07-21 Cymabay Therapeutics Inc Tratamiento de la obesidad y sus complicaciones.

Also Published As

Publication number Publication date
US20210220305A1 (en) 2021-07-22
US20190255004A1 (en) 2019-08-22
ZA201808360B (en) 2020-02-26
US11596614B2 (en) 2023-03-07
IL263372B2 (en) 2023-06-01
PL3463328T3 (pl) 2022-10-03
US10478411B2 (en) 2019-11-19
US11000494B2 (en) 2021-05-11
US10272058B2 (en) 2019-04-30
MX2018014915A (es) 2019-04-24
CN109195594A (zh) 2019-01-11
SI3463328T1 (sl) 2022-08-31
EP3463328A1 (en) 2019-04-10
WO2017209865A1 (en) 2017-12-07
HRP20220903T1 (hr) 2022-10-14
KR102408288B1 (ko) 2022-06-10
US20200061006A1 (en) 2020-02-27
BR112018074147A2 (pt) 2019-03-06
KR20190015363A (ko) 2019-02-13
US10813895B2 (en) 2020-10-27
HUE059838T2 (hu) 2023-01-28
IL263372A (en) 2018-12-31
AU2017274293B2 (en) 2022-03-31
ES2921230T3 (es) 2022-08-22
RU2018146504A3 (hu) 2020-07-27
US20210000774A1 (en) 2021-01-07
UA122719C2 (uk) 2020-12-28
US20170340589A1 (en) 2017-11-30
RU2018146504A (ru) 2020-07-09
EP3463328B1 (en) 2022-06-15
AU2017274293A1 (en) 2018-12-13
CA3024155C (en) 2023-10-10
DK3463328T3 (da) 2022-07-04
JP2019518022A (ja) 2019-06-27
NZ748721A (en) 2022-04-29
RU2765460C2 (ru) 2022-01-31
PT3463328T (pt) 2022-07-07
CA3024155A1 (en) 2017-12-07
LT3463328T (lt) 2022-08-10
JP7079735B2 (ja) 2022-06-02
RS63345B1 (sr) 2022-07-29

Similar Documents

Publication Publication Date Title
SG11201903857UA (en) Antibodies to pd-1 and uses thereof
SG11201907034PA (en) Methods of treating influenza
SG11201809344QA (en) Process for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzaldehyde
SG11201810123SA (en) Treatment of intrahepatic cholestatic diseases
SG11201811431VA (en) Multispecific antibodies against cd40 and cd137
SG11201907840RA (en) Fused imidazo-piperidine jak inhibitors
SG11201804132UA (en) Eif4-a-inhibiting compounds and methods related thereto
SG11201804758QA (en) Aqueous pharmaceutical formulation comprising anti-pd-1 antibody avelumab
SG11201810579YA (en) Pyrimidin-2-ylamino-1h-pyrazols as lrrk2 inhibitors for use in the treatment of neurodegenerative disorders
SG11201909960UA (en) Methods for improving memory and cognition and for treating memory and cognitive disorders
SG11201808222RA (en) Methods of treatment of cholestatic diseases
SG11201906436VA (en) Novel heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same
SG11201907583TA (en) Methods for treating complement-mediated diseases and disorders
SG11201908326YA (en) Methods of treating neurodegenerative diseases
SG11201811559WA (en) Cancer treatment combinations
SG11201901063SA (en) Therapeutic agents for neurodegenerative diseases
SG11201810965YA (en) 1h-pyrazolo[4,3-b]pyridines as pde1 inhibitors
SG11202000333UA (en) Bicyclic ketone compounds and methods of use thereof
SG11201809882XA (en) Pharmaceutical combinations for treating cancer
SG11201810143PA (en) Exon skipping oligomers for muscular dystrophy
SG11201808525UA (en) Anti-complement factor bb antibodies and uses thereof
SG11201804704PA (en) Compositions and methods for decreasing tau expression
SG11201909807TA (en) Methods of manufacturing of niraparib
SG11201903012RA (en) Anti-c1s antibodies and methods of use thereof
SG11201906313SA (en) A polypeptide linker for preparing multispecific antibodies