SG11201809575TA - Biocatalysts and methods for hydroxylation of chemical compounds - Google Patents

Biocatalysts and methods for hydroxylation of chemical compounds

Info

Publication number
SG11201809575TA
SG11201809575TA SG11201809575TA SG11201809575TA SG11201809575TA SG 11201809575T A SG11201809575T A SG 11201809575TA SG 11201809575T A SG11201809575T A SG 11201809575TA SG 11201809575T A SG11201809575T A SG 11201809575TA SG 11201809575T A SG11201809575T A SG 11201809575TA
Authority
SG
Singapore
Prior art keywords
california
penobscot
rpm
international
air
Prior art date
Application number
SG11201809575TA
Other languages
English (en)
Inventor
Jovana Nazor
Robert Osborne
Jack Liang
Jonathan Vroom
Xiyun Zhang
David Entwistle
Rama Voladri
Ravi Garcia
Jeffrey Moore
Shane Grosser
Birgit Kosjek
Matthew Truppo
Original Assignee
Codexis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codexis Inc filed Critical Codexis Inc
Publication of SG11201809575TA publication Critical patent/SG11201809575TA/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/11—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (1.14.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/11—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (1.14.11)
    • C12Y114/11002—Procollagen-proline dioxygenase (1.14.11.2), i.e. proline-hydroxylase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
SG11201809575TA 2016-06-09 2017-04-19 Biocatalysts and methods for hydroxylation of chemical compounds SG11201809575TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662347724P 2016-06-09 2016-06-09
PCT/US2017/028370 WO2017213758A1 (fr) 2016-06-09 2017-04-19 Biocatalyseurs et procédés d'hydroxylation de composés chimiques

Publications (1)

Publication Number Publication Date
SG11201809575TA true SG11201809575TA (en) 2018-11-29

Family

ID=60572322

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201809575TA SG11201809575TA (en) 2016-06-09 2017-04-19 Biocatalysts and methods for hydroxylation of chemical compounds

Country Status (6)

Country Link
US (4) US10184117B2 (fr)
EP (1) EP3469088B1 (fr)
CN (1) CN109715817B (fr)
IL (1) IL263448B2 (fr)
SG (1) SG11201809575TA (fr)
WO (1) WO2017213758A1 (fr)

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CN109715817B (zh) * 2016-06-09 2022-12-09 科德克希思公司 用于化合物的羟基化的生物催化剂和方法
CN106834244B (zh) * 2016-11-04 2021-07-06 凯莱英医药集团（天津）股份有限公司 脯氨酸羟化酶及其应用
CN113046250B (zh) * 2019-12-27 2023-01-24 上海医药工业研究院 生产纽莫康定b0的基因工程菌及其制备方法和应用
CN113046251B (zh) * 2019-12-27 2023-01-24 上海医药工业研究院 生产纽莫康定b0的基因工程菌、其制备方法及应用
IL300533A (en) 2020-08-28 2023-04-01 Codexis Inc Transgenic variants of amylase
CN117098847A (zh) 2020-08-28 2023-11-21 科德克希思公司 工程化蛋白酶变体
CA3197584A1 (fr) * 2020-11-13 2022-05-19 The Regents Of The University Of Colorado A Body Corporate Stabilite et activite d'enzymes par immobilisation

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Also Published As

Publication number Publication date
EP3469088B1 (fr) 2023-09-06
EP3469088A1 (fr) 2019-04-17
IL263448B2 (en) 2023-10-01
CN109715817B (zh) 2022-12-09
US20190078061A1 (en) 2019-03-14
CN109715817A (zh) 2019-05-03
IL263448A (en) 2019-02-03
IL263448B1 (en) 2023-06-01
US11634695B2 (en) 2023-04-25
US10184117B2 (en) 2019-01-22
US10844358B2 (en) 2020-11-24
US20210032605A1 (en) 2021-02-04
US20230272354A1 (en) 2023-08-31
US20170355968A1 (en) 2017-12-14
EP3469088C0 (fr) 2023-09-06
EP3469088A4 (fr) 2020-04-01
WO2017213758A1 (fr) 2017-12-14

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