SG11201804856VA - C-terminal lysine conjugated immunoglobulins - Google Patents

C-terminal lysine conjugated immunoglobulins

Info

Publication number
SG11201804856VA
SG11201804856VA SG11201804856VA SG11201804856VA SG11201804856VA SG 11201804856V A SG11201804856V A SG 11201804856VA SG 11201804856V A SG11201804856V A SG 11201804856VA SG 11201804856V A SG11201804856V A SG 11201804856VA SG 11201804856V A SG11201804856V A SG 11201804856VA
Authority
SG
Singapore
Prior art keywords
international
rule
pct
applicant
english
Prior art date
Application number
SG11201804856VA
Inventor
Jared Spidel
Earl Albone
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of SG11201804856VA publication Critical patent/SG11201804856VA/en

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    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
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    • C07K2317/55—Fab or Fab'

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Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization M1111101110101011111 HO 11111 0111010110111100 11111 00 111110111011# 11 International Bureau 0.. .... .. (10) International Publication Number (43) International Publication Date ..... ..or::,„, 22 June 2017(22.06.2017) WIPO I PCT WO 2017/106643 Al (51) International Patent Classification: KP, C07K 16/00 (2006.01) MD, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, (21) International Application Number: RU, PCT/US2016/067165 TH, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, (22) International Filing Date: ZA, ZM, ZW. 16 December 2016 (16.12.2016) (84) Designated States (unless otherwise indicated, for every (25) Filing Language: English kind GM, of regional protection available): ARIPO (BW, GH, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, (26) Publication Language: English TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, (30) Priority Data: TJ, 62/269,138 18 December 2015 (18.12.2015) US DK, LV, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, (71) Applicant: MORPHOTEK, INC. [US/US]; 210 Welsh SM, Pool Road, Exton, PA 19341 (US). GW, KM, ML, MR, NE, SN, TD, TG). TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, (72) Inventors: SPIDEL, Jared; 100 Wildbrier Road, Down- Declarations under Rule 4.17: ingtown, PA 19335 (US). ALBONE, Earl; 2105 Whitpain — as to Hills, Blue Bell, PA 19422 (US). applicant's entitlement to apply for and be granted a patent (Rule 4.1700) (74) Agents: ZACHARAKIS, Maria, Laccotripe et al.; Mc- as to the applicant's entitlement to claim the priority of the Carter & English, LLP, 265 Franklin Street, Boston, MA application (Rule 4.17(iii)) earlier 02110 (US). Published: (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, — with international search report (Art. 21(3)) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, _ before the expiration of the time limit for amending the BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, claims and to be republished in the event of receipt of DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, amendments (Rule 48.2(h)) HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, 1-1 M 7r © 11 IN 11 © \" (54) Title: C-TERMINAL LYSINE CONJUGATED IMMUNOGLOBULINS C ) „,.. (57) : Provided herein are conjugated immunoglobulins and methods for generating conjugated immunoglobulins using a microbial transglutaminase.
SG11201804856VA 2015-12-18 2016-12-16 C-terminal lysine conjugated immunoglobulins SG11201804856VA (en)

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IL302017A (en) 2020-10-25 2023-06-01 Araris Biotech Ag Means and methods for producing antibody-linker conjugates
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