SG11201809483UA - Production of steviol glycosides in recombinant hosts - Google Patents

Production of steviol glycosides in recombinant hosts

Info

Publication number
SG11201809483UA
SG11201809483UA SG11201809483UA SG11201809483UA SG11201809483UA SG 11201809483U A SG11201809483U A SG 11201809483UA SG 11201809483U A SG11201809483U A SG 11201809483UA SG 11201809483U A SG11201809483U A SG 11201809483UA SG 11201809483U A SG11201809483U A SG 11201809483UA
Authority
SG
Singapore
Prior art keywords
international
steviol
copenhagen
pct
glycosides
Prior art date
Application number
SG11201809483UA
Other languages
English (en)
Inventor
Iver Klavs Riishede Hansen
Veronique Douchin
Jens Houghton-Larsen
Esben Halkjaer Hansen
Angelika Semmler
Laura Occhipinti
Kim Olsson
Original Assignee
Evolva Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evolva Sa filed Critical Evolva Sa
Publication of SG11201809483UA publication Critical patent/SG11201809483UA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/56Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
SG11201809483UA 2016-05-16 2017-05-16 Production of steviol glycosides in recombinant hosts SG11201809483UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662337213P 2016-05-16 2016-05-16
PCT/EP2017/061774 WO2017198681A1 (en) 2016-05-16 2017-05-16 Production of steviol glycosides in recombinant hosts

Publications (1)

Publication Number Publication Date
SG11201809483UA true SG11201809483UA (en) 2018-11-29

Family

ID=58739035

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201809483UA SG11201809483UA (en) 2016-05-16 2017-05-16 Production of steviol glycosides in recombinant hosts

Country Status (9)

Country Link
US (2) US20190144907A1 (zh)
EP (1) EP3458598A1 (zh)
JP (1) JP2019519212A (zh)
CN (1) CN109477128A (zh)
AU (1) AU2017267214A1 (zh)
BR (1) BR112018073662A2 (zh)
CA (1) CA3023399A1 (zh)
SG (1) SG11201809483UA (zh)
WO (1) WO2017198681A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2906310T3 (es) 2016-08-12 2022-04-18 Amyris Inc Glicosiltransferasa dependiente de UDP para la producción de alta eficiencia de rebaudiósidos
ES2964976T3 (es) * 2016-10-14 2024-04-10 Conagen Inc Producción biosintética de glucósidos de esteviol y procesos para el mismo
EP3720968A1 (en) * 2017-12-05 2020-10-14 Evolva SA Production of steviol glycosides in recombinant hosts
US20210246156A1 (en) * 2018-06-08 2021-08-12 Purecircle Usa, Inc. High-purity steviol glycosides
CN110564658B (zh) * 2019-09-06 2021-08-17 广西大学 一株大肠杆菌工程菌及其全细胞催化生产甜菊醇的方法
CN112760301B (zh) * 2019-11-01 2023-01-17 中国科学院天津工业生物技术研究所 一种催化活性提高的糖基转移酶突变体及其应用
CN111235124B (zh) * 2020-01-19 2023-04-07 云南农业大学 珠子参糖基转移酶UGTPjm2及其在制备竹节参皂苷IVa上的应用
US11396646B2 (en) 2020-05-29 2022-07-26 QTG Development, Inc. Steviol glycosyltransferases and genes encoding the same
CN113308447B (zh) * 2021-05-31 2022-09-30 西南大学 拟南芥ugt74f2在催化苯乳酸合成苯乳酰葡萄糖中的应用
CN114736887A (zh) * 2022-03-25 2022-07-12 上海威高医疗技术发展有限公司 羧酸酯酶的用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009034080A (ja) * 2007-08-03 2009-02-19 Sanei Gen Ffi Inc 新規糖転移酵素、及びそれを利用した配糖体の製造
NZ708078A (en) * 2010-06-02 2017-01-27 Evolva Nutrition Inc Recombinant production of steviol glycosides
BR112014003037B1 (pt) * 2011-08-08 2022-04-05 Evolva Sa Hospedeiro recombinante e método para produzir um glicosídeo de esteviol
KR101791597B1 (ko) * 2011-11-23 2017-10-30 에볼바 에스아 모그로사이드 화합물을 효소에 의해 합성하기 위한 방법 및 재료
WO2014086842A1 (en) * 2012-12-04 2014-06-12 Evolva Sa Methods and materials for biosynthesis of mogroside compounds
EP2954058B1 (en) * 2013-02-06 2021-03-31 Evolva SA Methods for improved production of rebaudioside d and rebaudioside m
EP3039132A2 (en) * 2013-08-30 2016-07-06 Evolva SA A method for producing modified resveratrol
SG11201606673RA (en) * 2014-03-07 2016-09-29 Evolva Sa Methods for recombinant production of saffron compounds
CN107109358B (zh) * 2014-09-09 2022-08-02 埃沃尔瓦公司 在重组宿主中生产甜菊醇糖苷
CN104845990A (zh) * 2015-06-11 2015-08-19 山东大学 拟南芥糖基转移酶基因ugt73c7在提高植物抗病性中的应用

Also Published As

Publication number Publication date
BR112018073662A2 (pt) 2019-02-19
AU2017267214A1 (en) 2018-11-15
CN109477128A (zh) 2019-03-15
EP3458598A1 (en) 2019-03-27
WO2017198681A1 (en) 2017-11-23
JP2019519212A (ja) 2019-07-11
US20190144907A1 (en) 2019-05-16
US20220154234A1 (en) 2022-05-19
CA3023399A1 (en) 2017-11-23

Similar Documents

Publication Publication Date Title
SG11201809483UA (en) Production of steviol glycosides in recombinant hosts
SG11201811431VA (en) Multispecific antibodies against cd40 and cd137
SG11201803918VA (en) Production of steviol glycosides in recombinant hosts
SG11201809908TA (en) Stabilized glycopeptide antibiotic formulations
SG11201901506VA (en) Distributed systems for the efficient production and use of microbe-based compositions
SG11201909646TA (en) Trem2 antigen binding proteins and uses thereof
SG11201805838UA (en) Macrocyclic mcl1 inhibitors for treating cancer
SG11201908542QA (en) Gip receptor activating peptide
SG11201808856TA (en) Production of steviol glycosides in recombinant hosts
SG11201806624XA (en) Deposition of molybdenum thin films using a molybdenum carbonyl precursor
SG11201808457PA (en) Icos ligand variant immunomodulatory proteins and uses thereof
SG11201908325PA (en) Process for the preparation of glucuronide drug-linkers and intermediates thereof
SG11201803906PA (en) Control of cellular redox levels
SG11201810522UA (en) Anti-cd40 antibodies and their uses
SG11202000333UA (en) Bicyclic ketone compounds and methods of use thereof
SG11201908326YA (en) Methods of treating neurodegenerative diseases
SG11201811230RA (en) Compositions and methods for reducing ocular neovascularization
SG11201906853QA (en) Anti-rsv monoclonal antibody formulation
SG11201809830WA (en) Selective reduction of cysteine-engineered antibodies
SG11201901374WA (en) Antibiotic compounds
SG11201805649UA (en) Therapeutic anti-cd9 antibody
SG11201809875VA (en) Compositions and methods for treating spinal muscular atrophy
SG11201909856XA (en) Mesenchymal lineage precursor or stem cells with enhanced immunosuppression
SG11201808686VA (en) Synthesis of indazoles
SG11201902531QA (en) Liquid pharmaceutical composition