SG11201808237UA - Substituted indole compound derivatives as dengue viral replication inhibitors - Google Patents
Substituted indole compound derivatives as dengue viral replication inhibitorsInfo
- Publication number
- SG11201808237UA SG11201808237UA SG11201808237UA SG11201808237UA SG11201808237UA SG 11201808237U A SG11201808237U A SG 11201808237UA SG 11201808237U A SG11201808237U A SG 11201808237UA SG 11201808237U A SG11201808237U A SG 11201808237UA SG 11201808237U A SG11201808237U A SG 11201808237UA
- Authority
- SG
- Singapore
- Prior art keywords
- leuven
- international
- compounds
- dengue viral
- turnhoutseweg
- Prior art date
Links
- 208000001490 Dengue Diseases 0.000 title abstract 5
- 206010012310 Dengue fever Diseases 0.000 title abstract 5
- 208000025729 dengue disease Diseases 0.000 title abstract 5
- 229940123627 Viral replication inhibitor Drugs 0.000 title abstract 2
- SIKJAQJRHWYJAI-UHFFFAOYSA-N benzopyrrole Natural products C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title abstract 2
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 title abstract 2
- -1 indole compound Chemical class 0.000 title abstract 2
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000003814 drug Substances 0.000 abstract 4
- 208000036142 Viral infection Diseases 0.000 abstract 3
- 238000002360 preparation method Methods 0.000 abstract 3
- 230000009385 viral infection Effects 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 150000002475 indoles Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 102220240796 rs553605556 Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
- C07F9/5728—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16163482 | 2016-04-01 | ||
| PCT/EP2017/057662 WO2017167952A1 (fr) | 2016-04-01 | 2017-03-31 | Dérivés d'indole substitués utilisés en tant qu'inhibiteurs de réplication du virus de la dengue |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201808237UA true SG11201808237UA (en) | 2018-10-30 |
Family
ID=55650310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201808237UA SG11201808237UA (en) | 2016-04-01 | 2017-03-31 | Substituted indole compound derivatives as dengue viral replication inhibitors |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US10730884B2 (fr) |
| EP (1) | EP3436004A1 (fr) |
| JP (2) | JP7007290B2 (fr) |
| KR (1) | KR102359766B1 (fr) |
| CN (1) | CN109069482B (fr) |
| AU (1) | AU2017240076A1 (fr) |
| BR (1) | BR112018068956A2 (fr) |
| CA (1) | CA3013408A1 (fr) |
| CL (1) | CL2018002784A1 (fr) |
| CO (1) | CO2018009996A2 (fr) |
| CR (1) | CR20180494A (fr) |
| EA (1) | EA201892200A1 (fr) |
| EC (1) | ECSP18073264A (fr) |
| IL (1) | IL261947A (fr) |
| MA (1) | MA44502A (fr) |
| MX (1) | MX2018011786A (fr) |
| PH (1) | PH12018502026A1 (fr) |
| SG (1) | SG11201808237UA (fr) |
| SV (1) | SV2018005750A (fr) |
| WO (1) | WO2017167952A1 (fr) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201116559D0 (en) | 2011-09-26 | 2011-11-09 | Univ Leuven Kath | Novel viral replication inhibitors |
| GB201305376D0 (en) | 2013-03-25 | 2013-05-08 | Univ Leuven Kath | Novel viral replication inhibitors |
| JOP20160086B1 (ar) | 2015-05-08 | 2021-08-17 | 2 Katholieke Univ Leuven Ku Leuven Research And Development | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| JO3633B1 (ar) | 2015-09-16 | 2020-08-27 | Katholieke Univ Leuven Ku Leuven Research & Development | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| JOP20160198B1 (ar) | 2015-09-16 | 2022-03-14 | Janssen Pharmaceuticals Inc | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| SG11201808270PA (en) | 2016-03-31 | 2018-10-30 | Janssen Pharmaceuticals Inc | Substituted indoline derivatives as dengue viral replication inhibitors |
| SI3436435T1 (sl) | 2016-03-31 | 2021-08-31 | Janssen Pharmaceuticals, Inc. | Substituirani derivati indolina kot zaviralci replikacije virusa denga |
| JP7007290B2 (ja) | 2016-04-01 | 2022-01-24 | ヤンセン ファーマシューティカルズ，インコーポレーテッド | デングウイルス複製阻害剤としての置換インドール化合物誘導体 |
| JOP20170069B1 (ar) | 2016-04-01 | 2021-08-17 | 1 Janssen Pharmaceuticals Inc | مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| JOP20180026A1 (ar) | 2017-03-31 | 2019-01-30 | Univ Leuven Kath | مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| JOP20180025B1 (ar) | 2017-03-31 | 2021-08-17 | Janssen Pharmaceuticals Inc | مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| AU2018274100B2 (en) | 2017-05-22 | 2022-06-23 | Janssen Pharmaceuticals, Inc. | Substituted indoline derivatives as dengue viral replication inhibitors |
| IL270727B2 (en) | 2017-05-22 | 2023-03-01 | Janssen Pharmaceuticals Inc | Transduced indulin derivatives as inhibitors of dengue virus replication |
| CN108947948B (zh) * | 2018-06-12 | 2021-07-20 | 湖南大学 | 一种n-芳基萘并呋喃酮亚胺类化合物及其合成方法 |
| CN108586404A (zh) * | 2018-06-12 | 2018-09-28 | 湖南大学 | 一种n-芳基萘并呋喃酮亚胺类化合物的合成方法 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0110832D0 (en) | 2001-05-03 | 2001-06-27 | Virogen Ltd | Antiviral compounds |
| JP2005520795A (ja) | 2001-12-12 | 2005-07-14 | コンフォーマ・セラピューティクス・コーポレイション | Ｈｓｐ９０阻害活性を有するプリン類似体 |
| GB0215293D0 (en) | 2002-07-03 | 2002-08-14 | Rega Foundation | Viral inhibitors |
| CA2577745C (fr) * | 2004-09-30 | 2012-11-27 | Tibotec Pharmaceuticals Ltd. | Pyrimidines bicycliques inhibant le vhc |
| CN101103026A (zh) | 2005-01-14 | 2008-01-09 | 健亚生物科技公司 | 用于治疗病毒感染的吲哚衍生物 |
| CA2597213A1 (fr) | 2005-02-09 | 2006-09-14 | Migenix Inc. | Compositions et methodes permettant de traiter ou de prevenir les infections par les flaviviridae |
| WO2009039248A2 (fr) * | 2007-09-18 | 2009-03-26 | Stanford University | Méthodes de traitement d'une infection par un virus de la famille des flaviviridae et compositions pour le traitement d'une infection par un virus de la famille des flaviviridae |
| BRPI0909985A2 (pt) | 2008-06-03 | 2015-08-25 | Siga Technologies Inc | Composição farmacêutica e método para o tratamento ou profilaxia de uma infecção viral ou doença associada à mesma |
| US8143259B2 (en) | 2008-08-19 | 2012-03-27 | Janssen Pharmaceutica, Nv | Cold menthol receptor antagonists |
| GB0910003D0 (en) | 2009-06-11 | 2009-07-22 | Univ Leuven Kath | Novel compounds for the treatment of neurodegenerative diseases |
| US8993604B2 (en) | 2009-06-30 | 2015-03-31 | Siga Technologies, Inc. | Treatment and prevention of dengue virus infections |
| PT2523951E (pt) | 2010-01-15 | 2015-09-14 | Gilead Sciences Inc | Inibidores de vírus flaviviridae |
| GB201116559D0 (en) | 2011-09-26 | 2011-11-09 | Univ Leuven Kath | Novel viral replication inhibitors |
| GB201305376D0 (en) | 2013-03-25 | 2013-05-08 | Univ Leuven Kath | Novel viral replication inhibitors |
| DK3060547T3 (en) | 2013-10-23 | 2018-01-15 | Janssen Sciences Ireland Uc | CARBOXAMIDE DERIVATIVES AND USE THEREOF AS MEDICINES FOR TREATMENT OF HEPATITS B |
| EP3988549A1 (fr) | 2014-01-31 | 2022-04-27 | Bristol-Myers Squibb Company | Macrocycles avec des groupes p2' hétérocycliques en tant qu'inhibiteurs du facteur xia |
| CA2958022A1 (fr) * | 2014-10-01 | 2016-04-07 | Janssen Pharmaceuticals, Inc | Indoles monosubstitues ou disubstitues utilises en tant qu'inhibiteurs de la replication du virus de la dengue |
| RS58461B1 (sr) | 2014-10-01 | 2019-04-30 | Janssen Pharmaceuticals Inc | Mono- ili di-supstituisani derivati indola kao inhibitori replikacije virusa denge |
| NO2721243T3 (fr) | 2014-10-01 | 2018-10-20 | ||
| JOP20150335B1 (ar) | 2015-01-16 | 2022-03-14 | Janssen Pharmaceuticals Inc | مشتقات اندول بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| AR103680A1 (es) | 2015-02-23 | 2017-05-24 | Lilly Co Eli | Inhibidores selectivos de bace1 |
| JOP20160086B1 (ar) | 2015-05-08 | 2021-08-17 | 2 Katholieke Univ Leuven Ku Leuven Research And Development | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| JO3633B1 (ar) | 2015-09-16 | 2020-08-27 | Katholieke Univ Leuven Ku Leuven Research & Development | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| JOP20160198B1 (ar) | 2015-09-16 | 2022-03-14 | Janssen Pharmaceuticals Inc | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| PT3370698T (pt) | 2015-11-03 | 2022-03-02 | Zoetis Services Llc | Compósitos de polímero sol-gel e utilizações dos mesmos |
| SI3436435T1 (sl) | 2016-03-31 | 2021-08-31 | Janssen Pharmaceuticals, Inc. | Substituirani derivati indolina kot zaviralci replikacije virusa denga |
| CN109715613B (zh) | 2016-03-31 | 2021-07-30 | 武田药品工业株式会社 | 杂环化合物 |
| SG11201808270PA (en) | 2016-03-31 | 2018-10-30 | Janssen Pharmaceuticals Inc | Substituted indoline derivatives as dengue viral replication inhibitors |
| WO2017167832A1 (fr) | 2016-04-01 | 2017-10-05 | Basf Se | Composés bicycliques |
| CN109328074A (zh) | 2016-04-01 | 2019-02-12 | 凯德药业股份有限公司 | 嵌合抗原和t细胞受体及使用的方法 |
| MY201207A (en) | 2016-04-01 | 2024-02-09 | Amgen Inc | Chimeric receptors to flt3 and methods of use thereof |
| CR20210084A (es) | 2016-04-01 | 2021-03-26 | Amgen Inc | Receptores quiméricos y métodos de uso de los mismos (divisional 2018-0480) |
| JP7007290B2 (ja) | 2016-04-01 | 2022-01-24 | ヤンセン ファーマシューティカルズ，インコーポレーテッド | デングウイルス複製阻害剤としての置換インドール化合物誘導体 |
| CA3018986A1 (fr) | 2016-04-01 | 2017-10-05 | Signal Pharmaceuticals, Llc | Composes aminopurine substitues, compositions correspondantes, et procedes de traitement les utilisant |
| JOP20170069B1 (ar) | 2016-04-01 | 2021-08-17 | 1 Janssen Pharmaceuticals Inc | مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| JOP20180025B1 (ar) | 2017-03-31 | 2021-08-17 | Janssen Pharmaceuticals Inc | مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| JOP20180026A1 (ar) | 2017-03-31 | 2019-01-30 | Univ Leuven Kath | مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| AU2018274100B2 (en) | 2017-05-22 | 2022-06-23 | Janssen Pharmaceuticals, Inc. | Substituted indoline derivatives as dengue viral replication inhibitors |
| IL270727B2 (en) | 2017-05-22 | 2023-03-01 | Janssen Pharmaceuticals Inc | Transduced indulin derivatives as inhibitors of dengue virus replication |
-
2017
- 2017-03-31 JP JP2018549980A patent/JP7007290B2/ja active Active
- 2017-03-31 AU AU2017240076A patent/AU2017240076A1/en not_active Abandoned
- 2017-03-31 SG SG11201808237UA patent/SG11201808237UA/en unknown
- 2017-03-31 US US16/088,198 patent/US10730884B2/en active Active
- 2017-03-31 MX MX2018011786A patent/MX2018011786A/es unknown
- 2017-03-31 BR BR112018068956A patent/BR112018068956A2/pt not_active Application Discontinuation
- 2017-03-31 CR CR20180494A patent/CR20180494A/es unknown
- 2017-03-31 KR KR1020187027650A patent/KR102359766B1/ko active IP Right Grant
- 2017-03-31 EP EP17714752.7A patent/EP3436004A1/fr active Pending
- 2017-03-31 EA EA201892200A patent/EA201892200A1/ru unknown
- 2017-03-31 MA MA044502A patent/MA44502A/fr unknown
- 2017-03-31 CN CN201780022068.1A patent/CN109069482B/zh active Active
- 2017-03-31 WO PCT/EP2017/057662 patent/WO2017167952A1/fr active Application Filing
- 2017-03-31 CA CA3013408A patent/CA3013408A1/fr not_active Abandoned
-
2018
- 2018-09-21 PH PH12018502026A patent/PH12018502026A1/en unknown
- 2018-09-21 CO CONC2018/0009996A patent/CO2018009996A2/es unknown
- 2018-09-26 IL IL261947A patent/IL261947A/en unknown
- 2018-09-28 SV SV2018005750A patent/SV2018005750A/es unknown
- 2018-09-28 CL CL2018002784A patent/CL2018002784A1/es unknown
- 2018-09-28 EC ECSENADI201873264A patent/ECSP18073264A/es unknown
-
2021
- 2021-10-15 JP JP2021169228A patent/JP2022009166A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CL2018002784A1 (es) | 2018-12-14 |
| JP2019511502A (ja) | 2019-04-25 |
| US20190276467A1 (en) | 2019-09-12 |
| AU2017240076A1 (en) | 2018-08-09 |
| KR20180130502A (ko) | 2018-12-07 |
| CO2018009996A2 (es) | 2018-09-28 |
| MX2018011786A (es) | 2019-05-20 |
| IL261947A (en) | 2018-10-31 |
| BR112018068956A2 (pt) | 2019-01-22 |
| MA44502A (fr) | 2019-02-06 |
| ECSP18073264A (es) | 2018-10-31 |
| JP2022009166A (ja) | 2022-01-14 |
| KR102359766B1 (ko) | 2022-02-07 |
| US10730884B2 (en) | 2020-08-04 |
| SV2018005750A (es) | 2018-11-15 |
| CR20180494A (es) | 2019-01-29 |
| CA3013408A1 (fr) | 2017-10-05 |
| CN109069482B (zh) | 2022-04-05 |
| CN109069482A (zh) | 2018-12-21 |
| WO2017167952A1 (fr) | 2017-10-05 |
| PH12018502026A1 (en) | 2019-02-11 |
| JP7007290B2 (ja) | 2022-01-24 |
| EP3436004A1 (fr) | 2019-02-06 |
| EA201892200A1 (ru) | 2019-03-29 |
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