SG11201806214RA - Clinical assessment of m-protein response in multiple myeloma - Google Patents
Clinical assessment of m-protein response in multiple myelomaInfo
- Publication number
- SG11201806214RA SG11201806214RA SG11201806214RA SG11201806214RA SG11201806214RA SG 11201806214R A SG11201806214R A SG 11201806214RA SG 11201806214R A SG11201806214R A SG 11201806214RA SG 11201806214R A SG11201806214R A SG 11201806214RA SG 11201806214R A SG11201806214R A SG 11201806214RA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- pct
- clinical assessment
- mor202
- planegg
- Prior art date
Links
- 208000034578 Multiple myelomas Diseases 0.000 title abstract 2
- 206010035226 Plasma cell myeloma Diseases 0.000 title abstract 2
- 102000008100 Human Serum Albumin Human genes 0.000 abstract 1
- 108091006905 Human Serum Albumin Proteins 0.000 abstract 1
- 101710085938 Matrix protein Proteins 0.000 abstract 1
- 101710127721 Membrane protein Proteins 0.000 abstract 1
- 102100032965 Myomesin-2 Human genes 0.000 abstract 1
- 230000000116 mitigating effect Effects 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
- G01N33/561—Immunoelectrophoresis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57426—Specifically defined cancers leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Ecology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Electrochemistry (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16158714 | 2016-03-04 | ||
| PCT/EP2017/055011 WO2017149122A1 (en) | 2016-03-04 | 2017-03-03 | Clinical assessment of m-protein response in multiple myeloma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201806214RA true SG11201806214RA (en) | 2018-08-30 |
Family
ID=55745535
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201806214RA SG11201806214RA (en) | 2016-03-04 | 2017-03-03 | Clinical assessment of m-protein response in multiple myeloma |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US11618789B2 (enExample) |
| EP (1) | EP3423498A1 (enExample) |
| JP (4) | JP7362250B2 (enExample) |
| KR (1) | KR102427948B1 (enExample) |
| CN (1) | CN108699161B (enExample) |
| AU (2) | AU2017226960B2 (enExample) |
| CA (1) | CA3016098A1 (enExample) |
| IL (2) | IL305540B2 (enExample) |
| SG (1) | SG11201806214RA (enExample) |
| WO (1) | WO2017149122A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019209730A1 (en) | 2018-04-24 | 2019-10-31 | Helena Laboratories Corporation | Removal of interfering factors from serum protein electrophoresis profiles |
| BR112021004130A2 (pt) | 2018-09-11 | 2021-05-25 | Jiangsu Hengrui Medicine Co., Ltd. | anticorpo anti-cd38, fragmento de ligação ao antígeno do mesmo, e uso farmacêutico |
| WO2020187718A1 (en) | 2019-03-15 | 2020-09-24 | Morphosys Ag | Anti-cd38 antibodies and pharmaceutical compositions thereof for the treatment of autoantibody-mediated autoimmune disease |
| WO2023094696A1 (en) * | 2021-11-29 | 2023-06-01 | Morphosys Ag | Methods for reducing anti-cd38 mab drug interference in serological assays |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3912610A (en) * | 1974-07-23 | 1975-10-14 | Icl Scient | Method for electroquantitative determination of proteins |
| US4102990A (en) * | 1977-12-05 | 1978-07-25 | General Electric Company | Electrophoretic assay for antigen-antibody reaction based on particle-particle coupling |
| US4661586A (en) * | 1981-11-17 | 1987-04-28 | The Board Of Trustees Of The Leland Stanford Junior University | Monoclonal anti-idiotype antibodies |
| US4578350A (en) * | 1983-09-23 | 1986-03-25 | Syntex (U.S.A.) Inc. | Immunoassays employing protected labels |
| US6936464B1 (en) * | 1992-10-02 | 2005-08-30 | Cancer Research Technology Limited | Immune responses to fusion proteins |
| US20020164788A1 (en) | 1994-12-02 | 2002-11-07 | The Wellcome Foundation Limited | Humanized antibodies to CD38 |
| JP2003524587A (ja) | 1998-06-05 | 2003-08-19 | マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチ | 多発性骨髄腫を処置するための、ｃｄ３８に対する、遺伝子操作した抗体の使用 |
| EP1174440A1 (en) | 2000-07-19 | 2002-01-23 | U-BISys B.V. | A selectively-expressed epitope on the human CD38 molecule detected by a phage display library-derived human scFv antibody fragment |
| US7348139B1 (en) * | 2001-04-13 | 2008-03-25 | The Johns Hopkins University School Of Medicine | SOCS-1 gene methylation in cancer |
| US6902669B2 (en) | 2002-09-13 | 2005-06-07 | Fleetguard, Inc. | Filter cartridge with floating seal |
| EP1544215A1 (en) | 2003-12-17 | 2005-06-22 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Human anti-idiotypic antibody fragments that mimic HER-2/neu |
| CA2555185C (en) * | 2004-02-06 | 2020-03-24 | Morphosys Ag | Anti-cd38 human antibodies and uses therefor |
| JP2008504013A (ja) | 2004-02-06 | 2008-02-14 | モルフォシス・アクチェンゲゼルシャフト | 抗ｃｄ３８ヒト抗体及びその用途 |
| WO2006089133A2 (en) * | 2005-02-15 | 2006-08-24 | Duke University | Anti-cd19 antibodies and uses in oncology |
| EA015584B1 (ru) * | 2005-03-23 | 2011-10-31 | Генмаб А/С | Антитело к cd38 человека и его применение |
| AR053489A1 (es) | 2005-05-24 | 2007-05-09 | Morphosys Ag | Generacion perfilado de anticuerpos terapeuticos totalmente derivados de hucal gold humanos especificos para cd38 humano |
| JP5362359B2 (ja) | 2005-10-12 | 2013-12-11 | モルフォシス アーゲー | ヒトＣＤ３８に特異的な完全ヒトＨｕＣＡＬＧＯＬＤ由来の治療抗体の生成とプロファイリング |
| EP2046367A4 (en) * | 2006-06-07 | 2009-11-11 | Human Genome Sciences Inc | ALBUM INFUSION PROTEINS |
| US20080066739A1 (en) * | 2006-09-20 | 2008-03-20 | Lemahieu Edward | Methods and systems of delivering medication via inhalation |
| US9382327B2 (en) * | 2006-10-10 | 2016-07-05 | Vaccinex, Inc. | Anti-CD20 antibodies and methods of use |
| EP1914242A1 (en) | 2006-10-19 | 2008-04-23 | Sanofi-Aventis | Novel anti-CD38 antibodies for the treatment of cancer |
| EP2193145A4 (en) * | 2007-08-28 | 2011-05-18 | Abbott Biotech Ltd | COMPOSITIONS AND METHODS COMPRISING BINDING PROTEINS FOR ADALIMUMAB |
| US20110151494A1 (en) * | 2008-06-30 | 2011-06-23 | H. Lee Moffit Cancer & Research Institute | Methods and materials for monitoring myeloma using quantitative mass spectrometry |
| EP2580243B1 (en) | 2010-06-09 | 2019-10-16 | Genmab A/S | Antibodies against human cd38 |
| LT2621531T (lt) | 2010-09-27 | 2017-04-10 | Morphosys Ag | Anti-cd38 antikūnas ir lenalidomidas arba bortezomibas, skirti išsėtinės mielomos ir nhl (nehodžino limfoma) gydymui |
| JP2014504850A (ja) | 2010-09-30 | 2014-02-27 | メルク・シャープ・エンド・ドーム・コーポレイション | 抗ｈｅｒ３抗体の製造、特徴づけ及びその用途 |
| JOP20210044A1 (ar) | 2010-12-30 | 2017-06-16 | Takeda Pharmaceuticals Co | الأجسام المضادة لـ cd38 |
| DK2831237T3 (en) | 2012-03-30 | 2018-03-05 | Univ Oklahoma | HIGH-MOLECULAR HEPAROSAN POLYMERS AND METHODS OF PRODUCING AND USING THEREOF |
| HUE036518T2 (hu) | 2012-09-25 | 2018-07-30 | Morphosys Ag | Kombinációk és alkalmazásaik |
| ES2774976T3 (es) | 2013-04-29 | 2020-07-23 | Teva Pharmaceuticals Australia Pty Ltd | Anticuerpos anti-CD38 y fusiones con interferón alfa-2b atenuado |
| EP3063173B1 (en) | 2013-10-31 | 2020-07-29 | Sanofi | Specific anti-cd38 antibodies for treating human cancers |
| JP6673838B2 (ja) | 2014-02-14 | 2020-04-01 | セレクティスＣｅｌｌｅｃｔｉｓ | 免疫細胞と病的細胞の両方に存在する抗原を標的とするように操作された、免疫療法のための細胞 |
-
2017
- 2017-03-03 AU AU2017226960A patent/AU2017226960B2/en active Active
- 2017-03-03 JP JP2018545438A patent/JP7362250B2/ja active Active
- 2017-03-03 SG SG11201806214RA patent/SG11201806214RA/en unknown
- 2017-03-03 WO PCT/EP2017/055011 patent/WO2017149122A1/en not_active Ceased
- 2017-03-03 IL IL305540A patent/IL305540B2/en unknown
- 2017-03-03 CA CA3016098A patent/CA3016098A1/en active Pending
- 2017-03-03 KR KR1020187026496A patent/KR102427948B1/ko active Active
- 2017-03-03 CN CN201780014944.6A patent/CN108699161B/zh active Active
- 2017-03-03 EP EP17708766.5A patent/EP3423498A1/en active Pending
- 2017-03-03 US US16/080,870 patent/US11618789B2/en active Active
- 2017-03-03 IL IL260750A patent/IL260750B2/en unknown
-
2022
- 2022-02-03 JP JP2022015613A patent/JP7331168B2/ja active Active
-
2023
- 2023-02-14 US US18/168,930 patent/US20230203189A1/en not_active Abandoned
- 2023-08-08 JP JP2023129240A patent/JP7557023B2/ja active Active
-
2024
- 2024-03-07 AU AU2024201503A patent/AU2024201503A1/en active Pending
- 2024-08-13 US US18/802,877 patent/US20240392034A1/en active Pending
- 2024-09-11 JP JP2024157490A patent/JP2024169455A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20230203189A1 (en) | 2023-06-29 |
| CN108699161B (zh) | 2022-06-03 |
| CA3016098A1 (en) | 2017-09-08 |
| JP7557023B2 (ja) | 2024-09-26 |
| IL260750B1 (en) | 2023-10-01 |
| KR20180118151A (ko) | 2018-10-30 |
| JP2019513346A (ja) | 2019-05-30 |
| CN108699161A (zh) | 2018-10-23 |
| JP2022058881A (ja) | 2022-04-12 |
| KR102427948B1 (ko) | 2022-08-02 |
| IL305540B2 (en) | 2024-09-01 |
| WO2017149122A1 (en) | 2017-09-08 |
| US11618789B2 (en) | 2023-04-04 |
| AU2024201503A1 (en) | 2024-03-28 |
| IL305540A (en) | 2023-10-01 |
| IL260750B2 (en) | 2024-02-01 |
| IL260750A (enExample) | 2018-09-20 |
| US20190077875A1 (en) | 2019-03-14 |
| JP2024169455A (ja) | 2024-12-05 |
| IL305540B1 (en) | 2024-05-01 |
| US20240392034A1 (en) | 2024-11-28 |
| JP7362250B2 (ja) | 2023-10-17 |
| JP7331168B2 (ja) | 2023-08-22 |
| EP3423498A1 (en) | 2019-01-09 |
| JP2023157927A (ja) | 2023-10-26 |
| AU2017226960B2 (en) | 2024-03-21 |
| AU2017226960A1 (en) | 2018-08-09 |
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